Abstract: The present invention provides a substrate for a semiconductor device and a semiconductor device using the same. The substrate for a semiconductor device comprises a ceramic supporting base plate formed by a polycrystalline aluminum nitride (AlN) sintered body; at least one silicon oxide layer formed on the base plate by a sol-gel method wherein the at least one silicon oxide layer has an average roughness less than the base plate to block polycrystalline orientation of the base plate and has a total thickness in a range of 10˜5000 nm, the silicon oxide layer is only formed from the sol-gel method and is not single crystalline; a first buffer layer comprising aluminum nitride (AlN) on the at least one silicon oxide layer with a thickness of 0.1˜10 ?m; and a gallium nitride layer formed on the first buffer layer and having a single-crystal crystalline structure.

Abstract: A foldable parabolic solar collector includes a first panel having a semi-parabolic reflective inner surface, a central tube to which the first panel is fixed, and a second panel having a semi-parabolic reflective inner surface. The second panel is pivotably mounted to the central tube with the reflective inner surface of the second panel facing the reflective inner surface of the first panel. A receiver tube carries a heat transfer fluid. A tracking motor rotates the central tube. A torque sensor lies in between the tracking motor and the central tube and is configured to measure torque between the tracking motor and the central tube. A servomotor pivots the second panel about the central tube between an open position and a closed position when it is determined by a controller that the torque between the tracking motor and the central tube exceeds a predetermined torque threshold.

Abstract: A method and a system for generating adaptive fast forward of egocentric videos are provided here. The method may include the following steps: obtaining a video footage containing a sequence of image frames captured by a non-stationary capturing device; estimating a moving direction of the non-stationary capturing device for a plurality of frames in the sequence of image frames; and generating a shortened video footage having fewer frames than said video footage, by sampling the sequence of image frames, wherein the sampling is carried out by selecting specific image frames and that minimize an overall cost associated with a deviation from a specific direction related to the moving direction, calculated for each of said plurality of image frames.

Abstract: A data access method based on a cloud computing platform, and a user terminal, are provided. The method is performed by a user terminal, and the method includes obtaining an access request for a data ciphertext of the cloud computing platform, the access request including a decryption key, and the decryption key including a user precise identity identifier and a user attribute identifier. The method further includes decrypting the data ciphertext into a data plaintext, in response to the user precise identity identifier belonging to an identity identifier set included in an access structure of the data ciphertext and/or in response to the user attribute identifier belonging to a user attribute identifier set included in the access structure of the data ciphertext.

Abstract: In some aspects, the present disclosure provides novel ligands, which may be used to make novel MRI contrast agents for the detection of zinc. In further aspects, by the present disclosure also provides methods of using as imaging agents and compositions thereof.

Abstract: This disclosure relates to particles comprising recombinant proteins, pharmaceutical composition comprising the particles, and therapeutic uses related thereto. In certain embodiments, the particles are made by the process of producing recombinant proteins and conjugating the recombinant proteins to form nanoparticles with a linking reagent comprising disulfide bonds. Typically the recombinant protein has a polypeptide of viral, fungal, or bacterial origin such as secreted effector proteins AvrA and YopJ. In certain embodiments, the disclosure relates to treating or preventing autoimmune diseases, cancer, or inflammatory diseases, or conditions such as inflammatory bowel disease (IBD).

Abstract: The present invention relates to a non-volatile ferroelectric memory device including a semiconductor active layer, a plurality of memory cells connected in series on the semiconductor active layer, and a control circuit for performing a read operation and a program operation on the selected memory cell among the plurality of memory cells, each of the memory cells comprising a para-dielectric layer on the semiconductor active layer; a dielectric stack including a ferroelectric layer stacked on the para-dielectric layer and a charge trap site for generating a negative capacitance effect of the ferroelectric layer by charges disposed and trapped at an interface between the ferroelectric layer and the para-dielectric layer; and a control gate electrode on the ferroelectric layer.

Abstract: Using processes disclosed herein, materials and structures are created and used. For example, processes can include melting boron nitride or amorphous carbon into an undercooled state followed by quenching. Exemplary new materials disclosed herein can be ferromagnetic and/or harder than diamond. Materials disclosed herein may include dopants in concentrations exceeding thermodynamic solubility limits. A novel phase of solid carbon has structure different than diamond and graphite.

Abstract: The present invention relates to a method and a system for compressing data from a smart meter. The method comprises: LZ-encoding electricity load data collected by the smart meter whenever the smart meter collects the electricity load data; storing the LZ-encoded electricity load data in a temporary database through a smart grid communication channel; reading the electricity load data from the temporary database every preset second duration, wherein the read electricity load data is electricity load data stored in the temporary database within the second duration before a corresponding reading time point; and LZ-decoding the read electricity load data, SAX-compressing the LZ-decoded electricity load data, and storing the SAX-compressed electricity load data in a data center. The present invention has high compression rate, reduces the transmission burden for communication lines and storage burden for the data center, and improves the efficiency of smart electricity data analysis and mining.

Abstract: Provided herein are novel small-molecules that have use in the inhibition of Eis, which mediates kanamycin resistance in Mycobacterium tuberculosis. The presently-disclosed subject matter further includes a pharmaceutical composition including a small molecule inhibitor, as described herein, and a suitable pharmaceutical carrier. Methods of treating tuberculosis comprising administering to an individual an effective amount of the disclosed small molecule inhibitors to mediate kanamycin A resistance and treat tuberculosis are also provided.

Abstract: Devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore are provided. The devices and methods also determine (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.

Abstract: This invention discloses devices and methods for high throughput skin sensitization detection. The devices comprise a microfabricated chamber comprising a region having one or more input channels and an outlet, and a face suitable for mounting a skin tissue and in fluidic communication with the region. The devices can be used in the methods for determining a prognosis of sensitization in an animal subject and identifying compounds that do not cause sensitization and thus are suitable for preparing cosmetic compositions.

Abstract: A triazole bridged flavonoid dimer compound library was efficiently constructed via the cycloaddition reaction of a series of flavonoid-containing azides (Az 1-15) and alkynes (Ac 1-17). These triazole bridged flavonoid dimers and their precursor alkyne- and azide-containing flavonoids were screened for their ability to modulate multidrug resistance (MDR) in P-gp-overexpressed cell line (LCC6MDR), MRP1-overexpressed cell line (2008/MRP1) and BCRP-overexpressed cell line (HEK293/R2 and MCF7-MX100). Generally, they displayed very promising MDR reversal activity against P-gp-, MRP1- and BCRP-mediated drug resistance. Moreover, they showed different levels of selectivity for various transporters. Overall, they can be divided into mono-selective, dual-selective and multi-selective modulators for the P-gp, MRP1 and BCRP transporters.

Abstract: System and method for monitoring the condition of electricity conductor support systems, i.e. towers, in a power network distribution system employing a tower structure integrity sensor assemblage. The system allows for identifying particular portions of a structural system for maintenance attention. The tower sensors allow identification of structural failures of electricity transmission towers.

Abstract: Various methods and systems are provided for cryogenic heat transfer by nanoporous surfaces. In one embodiment, among others, a system includes a cryogenic fluid in a flow path of the system; and a system component in the flow path that includes a nanoporous surface layer in contact with the cryogenic fluid. In another embodiment, a method includes providing a cryogenic fluid; and initiating chilldown of a cryogenic system by directing the cryogenic fluid across a nanoporous surface layer disposed on a surface of a system component.

Abstract: Systems and methods to perform privacy-aware computer-vision-based human activity monitoring with real-time haptic feedback. The system and method described in this disclosure employing a registration process for consenting human subjects before their activities are monitored. The registration process involves the corroboration of human motion captured in different modalities, i.e., computer-vision-based via the programmable computer-vision-based motion sensor and accelerometer-based via the wearable device. The tracked human activities are assessed in real-time and upon detection of activities that violated predefined rules, haptic feedback is delivered in real-time to the tracked human subject via the wearable device worn by the caregiver.

Abstract: An electrometer includes a sensing module and a control module. The sensing module includes an electrostatic sensing element. The electrostatic sensing element includes two opposite ends. Each end of the electrostatic sensing element is electrically connected to the control module. When an object with electrostatic charge is near but does not touch the electrostatic sensing element, the resistance of the electrostatic sensing element can be changed. The control module electrically connect to the electrostatic sensing element, the control module measures the resistance variation ?R of the electrostatic sensing element and converts the resistance variation ?R into the static electricity potential.

Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.

Abstract: The measuring cup includes numerous embodiments configured for a user to precisely determine the cup contents without need to lift the cup to one's eye level or to lower the eye level to the level of the cup contents. The various embodiments include folding cups; cups having transparent passages in the wall; cups having adjustably positionable bottoms; cups having level indicator rods in the cup interior extending upward from the cup bottom; cups having one or more filaments extending across the cup interior; cups having rigid level indicators spanning the cup interior; cups having adjustably positionable level indicator tabs therein; cups having buoyant level indicator tabs adjustably positionable in the cup interior; and cups having removable clip-on scales extending down along the interior of the cup wall, the scales having a plurality of attachment points for the removable attachment of a level indicator tab at a desired attachment point.

Abstract: Provided are compositions and methods for treating a condition or disorder mediated by fascin activity in a subject in need thereof which method comprises administering to the subject a therapeutically effective amount of at least one compound of any one of Formula I-a to I-n, II, II-a, II-b or III or a pharmaceutically acceptable salt thereof.