Abstract: Control of electrical conductivity is provided via electrically conductive magnetic domain walls between magnetic domains. The magnetic domains are identical except for their magnetic configuration. Altering a configuration of the magnetic domains (e.g., by thermal treatment, application of a magnetic field, etc.) can alter the electrical resistance of a device. Such devices can be used as non-volatile information storage devices or as sensors.

Abstract: The present invention provides novel methods and compositions useful for a fast and efficient chemical conjugation method of making hetero-arm polymers based on thiourea-catechol coupling. This novel conjugation method are useful in a wide variety of applications relating to the modification, ligation, and conjugation of large or small molecules to each other as well as to solid surface, including the making of adhesive materials such as hydrogels.

Abstract: Medical apparatus are disclosed for optoacoustic monitoring of an indwelling unit of the apparatus, where the indwelling unit includes one or more optical components capable of directing pulsed light into an overlying tissue. The apparatus also include one or more acoustic components in contact with an exterior surface of the tissue to detect induced pressure waves producing an acoustic output analyzed with an optoacoustic unit to monitor and confirm proper placement of the indwelling unit. Methods for using the apparatus are also disclosed.

Abstract: Thermally activated delayed fluorescent compounds and uses thereof are described. The thermally activated delayed fluorescent compounds are an analogs of 9,10-dihydro-9,9-dimethylacridine compounds.

Abstract: Apparatus, methods, and other embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The varying parameters may include flip angle, echo time, RF amplitude, and other parameters. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals, and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals. The reference signals may be stored in a dictionary. Singular value decomposition may be applied to the dictionary and the acquired signals before comparing the acquired signals to the reference signals.

Abstract: In some embodiments, the effect of uniformly dispersing carbon nanotubes in the material is achieved by including Ag in the carbon nanotubes to suppress the aggregation of carbon nanotubes when the electrical contacts are prepared.

Abstract: An overcoat that imparts a superhydrophobic surface to a painted surface of an object is a suspension of hydrophobic particles in a polymeric binder and a plasticizer in a solvent or mixed solvent. The particles are a metal oxide that is surface functionalized with a fluorinated alkyl silane or an alkyl silane. Surfaces coated using this paint display contact angles in excess of 150° and resist abrasion while retaining superhydrophobicity.

Abstract: A flipped fitting method that performs a flipped curve fitting on a maximum of 256 MRI images obtained at different echo times using an EPI image which obtains a plurality of MRI images at a plurality of different echo times within a TR period after application of an excitation RF pulse. Then, T2* values are fitted based on a sufficient amount of acquired TE images, such that it is possible to provide much more accurate T2* values than these provided by underestimated or overestimated fitting by the existing method which is based on only 12 images and to obtain rapid and accurate data without nerve stimulation or acoustic noise. Further, the flipped fitting method is more suitable and accurate for showing the real T2* values.

Abstract: An electrometer includes a sensing module and a control module. The sensing module includes an electrostatic sensing element. The electrostatic sensing element includes two opposite ends. Each end of the electrostatic sensing element is electrically connected to the control module. When an object with electrostatic charge is near but does not touch the electrostatic sensing element, the resistance of the electrostatic sensing element can be changed. The control module electrically connect to the electrostatic sensing element, the control module measures the resistance variation ?R of the electrostatic sensing element and converts the resistance variation ?R into the static electricity potential.

Abstract: The present invention relates to a polymer scaffold design and method for treating segmental long bone defects without amputation that permits permanent regrowth of bone in the area of the segmental defect, without external fixation or other problems inherent in current systems. The polymer scaffold is preferably made from a poly(ester urea) polymer and includes an outer shell, sized to fit over a segmental defect in a bone, and a collagen containing material. In some embodiments, the collagen containing material is placed in a polymer insert sized to fit within the segmental bone defect and within said outer shell. In some embodiments, the outer shell may contain struts running longitudinal struts along the inside surface of the outer shell. In some of these embodiments, the insert will have a corresponding set of grooves sized to receive the struts.

Abstract: Systems and methods to perform privacy-aware computer-vision-based human activity monitoring with real-time haptic feedback. The system and method described in this disclosure employing a registration process for consenting human subjects before their activities are monitored. The registration process involves the corroboration of human motion captured in different modalities, i.e., computer-vision-based via the programmable computer-vision-based motion sensor and accelerometer-based via the wearable device. The tracked human activities are assessed in real-time and upon detection of activities that violated predefined rules, haptic feedback is delivered in real-time to the tracked human subject via the wearable device worn by the caregiver.

Abstract: The guava seed (Psidium guajava) nanoparticles as an antibacterial agent are prepared from guava seeds that have been washed, dried, and ground to powder of less than 1 mm diameter. The powder is reduced to nanoparticle size (less than 100 nm diameter) by adding the powder to a solution of concentrated hydrochloric acid (38% w/w) and stirring the mixture at 3000 rpm at room temperature. The resulting nanoparticles are filtered through a Millipore membrane filter and dried. Agar well diffusion studies showed significant antibacterial activity against various Gram positive and negative species commonly implicated in food contamination. Further testing showed the guava seed nanoparticles have significant antioxidant and radical scavenging content, suggesting that guava seed nanoparticles may serve as an antibacterial agent.

Abstract: The present disclosure provides methods for the treatment of a mammal having a neurological condition, disease, or injury. The methods involve increasing the number of functional GABAergic interneurons at or near the site of the neurological disease, injury, or condition.

Abstract: A computer-implemented method for determining position of a mobile device using magnetic beacons including detecting, by a sensor in the mobile device, a magnetic signal having a unique signature associated with a given magnetic beacon; storing location and an associated signature for each of a plurality of magnetic beacons in a data store of the mobile device, where each of the magnetic beacons is assigned a different signature; extracting the unique signature from the magnetic signal; comparing the extracted signature to each of the signatures stored in the data store; identifying a given magnetic beacon from the plurality of magnetic beacons, where signature for the given beacon matches the extracted signature; and retrieving the location for the given magnetic beacon for the data store and correlating location of the mobile device with the location of the given magnetic beacon.

Abstract: An photosensitive device, the sensor comprising: a plurality of photosensitive units distributed in an array, each photosensitive unit configured to receive and convert light signal, wherein the photosensitive unit comprises a detecting element and a polarizer, the detecting element comprises a carbon nanotube structure comprising a plurality of carbon nanotubes oriented along the same direction, and the polarizer is configured to generate polarized light to irradiate a part surface of the carbon nanotube structure; a measuring device configured to measure temperature differences or potential differences generated in the carbon nanotube structure by irradiating; a data processor configured to analyze and calculate the potential differences or the temperature differences to obtain the wavelength of the light signal.

Abstract: The invention describes antibodies having a high affinity for aggregated forms of ?-synuclein and a low affinity for monomeric forms of ?-synuclein. The antibodies are useful in the diagnosis of neurodegenerative diseases.

Abstract: The present invention relates to a device for measuring the antimicrobial activity of a gas and a method for measuring the antimicrobial activity of a gas. The present invention can be used as a standardized device for measuring the antimicrobial activity of a gas or as a standardized method for measuring the antimicrobial activity of a gas as the present invention is capable of constantly maintaining the concentration of a gas and identifying the growth and development of microorganisms objectively through a color change of a microorganism culture medium containing a pH indicator.

Abstract: The present invention provides novel inhibitors of TAK1 having formula (I) and methods of using such compounds to treat various diseases.

Abstract: Provided herein are novel small-molecules that have use in the inhibition of Eis, which mediates kanamycin resistance in Mycobacterium tuberculosis. The presently-disclosed subject matter further includes a pharmaceutical composition including a small molecule inhibitor, as described herein, and a suitable pharmaceutical carrier. Methods of treating tuberculosis comprising administering to an individual an effective amount of the disclosed small molecule inhibitors to mediate kanamycin A resistance and treat tuberculosis are also provided.

Abstract: Devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore are provided. The devices and methods also determine (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.