Patents Assigned to University
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Publication number: 20240404623Abstract: Methods and systems for phenotyping based on a neural network model are provided. Training the model includes generating a dataset of individual-specific variant graphs associated representing dependencies among variants in individuals' genomes based on biomedical domain knowledge labelled according to target phenotype values to be predicted, and training the model using the training dataset to generate a phenotype prediction from an input individual-specific variant graph. Measure the contribution of a genetic variant to a phenotype of a target individual includes generating an individual-specific variant graph for the individual, modifying the individual-specific variant graph to remove a genetic variant, providing the initial and the modified individual-specific variant graphs as input to the phenotyping neural network model to generate two phenotype predictions, and calculating a difference between the two predictions, providing a measure of the contribution of the genetic variant to the phenotype.Type: ApplicationFiled: May 30, 2024Publication date: December 5, 2024Applicant: The Royal Institution for the Advancement of Learning/McGill UniversityInventors: John TRAKADIS, Lin Qi, Sameer SARDAAR
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Publication number: 20240401134Abstract: Among the various aspects of the present disclosure is the provision of methods and systems for detecting cell states in a biological sample. An aspect of the present disclosure provides for a method of determining cell type or cell states. In some embodiments, the method comprises providing or having been provided a sample comprising DNA or RNA and generating a methylation profile for the DNA or RNA in the sample or providing or having been provided a methylation profile of the DNA or RNA in the sample.Type: ApplicationFiled: October 18, 2020Publication date: December 5, 2024Applicants: Washington University, The Board Of Trustees Of The Leland Stanford Junior UniversityInventors: Aadel Chaudhuri, Irfan Alahi, Aaron Newman
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Publication number: 20240399907Abstract: A system may mitigate leakage currents in charging stations for electric vehicles. The system may include a bank of one or more parallel capacitors per phase electrically coupled to an AC voltage source, wherein a neutral point of the one or more parallel capacitors is electrically coupled to a DC ground; a bank of one or more inductors per phase electrically coupled to the one or more parallel capacitors, wherein each inductor is in series with and downstream from one capacitor; a rectifier electrically coupled to and downstream from the one or more parallel inductors, wherein the rectifier converts the AC voltage source to a DC voltage for supply to a battery; a DC bus electrically coupled to the rectifier; and a controller, wherein the controller is configured to mitigate leakage currents by controlling a voltage of at least one of the bank of one or more parallel capacitors.Type: ApplicationFiled: January 17, 2024Publication date: December 5, 2024Applicants: The Trustees of Columbia University in the City of New York, Longmax Corporation Ltd.Inventors: William-Michael Eull, Liwei Zhou, Weizhong Wang, Gangqi Cen, Matthias Preindl
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Publication number: 20240403386Abstract: A method for an anomaly detection is provided. The method may include acquiring a score predictor trained using normal time-series data, wherein the score predictor is a deep learning model configured to output a conditional score for previous time-series data and the conditional score represents a gradient of data density, extracting data for a specific time and data segments corresponding to a period before the specific time from target time-series data, and predicting a conditional score for the data segments through the trained score predictor and conducting an anomaly determination for the data for the specific time using the predicted conditional score.Type: ApplicationFiled: May 30, 2024Publication date: December 5, 2024Applicants: SAMSUNG SDS CO, LTD., UIF (University Industry Foundation), Yonsei UniversityInventors: Hak Soo LIM, Min-Jung KIM, Se Won PARK, No Seong PARK
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Publication number: 20240401264Abstract: A method of making an antimicrobial textile comprising TiO2 nanoparticles is described. The TiO2 nanoparticles are immobilized by first treating a textile with a base, and then contacting with TiO2 nanoparticles in a solution of an alcohol and acid. The textile may be subsequently irradiated with UV light prior to use. The antimicrobial textile shows high effectiveness against the growth and proliferation of microorganisms transmitted within indoor environments.Type: ApplicationFiled: August 13, 2024Publication date: December 5, 2024Applicant: Imam Abdulrahman Bin Faisal UniversityInventors: Khaled SALAMA, Reem Y AL JINDAN
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Publication number: 20240399181Abstract: A method for predictive fire control, comprising identifying a plurality of wildfire risk points on a power grid, calculating a route for an unmanned aerial vehicle (UAV) to intersect with a maximum number of points as a function of a range of the UAV, controlling the UAV to traverse the route, monitoring one or more sensors for an indication of a wildfire event and controlling the UAV to release a fire retardant on the fire.Type: ApplicationFiled: May 31, 2024Publication date: December 5, 2024Applicant: The Texas A&M University SystemInventors: Amarachi Tochi Umunnakwe, Katherine Rogers Davis
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Publication number: 20240403685Abstract: A method of performing a quantum gate operation using a quantum system wherein the quantum system comprises two or more neutral atoms, wherein each atom of the two or more neutral atoms is configured to transition between atomic states comprising: a first hyperfine ground state of the atom, a second hyperfine ground state of the atom, a Rydberg state and at least one intermediate excited state, wherein the quantum system further comprises an interaction between the Rydberg states of the two or more neutral atoms, and wherein the method comprises: generating a pulse sequence and providing the generated pulse sequence to the two or more neutral atoms to transition the atoms between said atomic states, wherein the pulse sequence takes into account at least part of the hyperfine structure of the at least one intermediate atomic state.Type: ApplicationFiled: June 13, 2024Publication date: December 5, 2024Applicant: University of StrathclydeInventors: Gerard Pelegri, Andrew Daley, Jonathan Pritchard
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Publication number: 20240399581Abstract: A robot system comprising a robot arm, a robot controller for controlling the robot arm and a safety system monitoring the robot arm, where the safety system is configured to bring the robot arm into a safe mode based on at least one safety function evaluated by the safety system. The robot controller is configured to specify at least one user-defined safety parameter range; provide the user-defined safety parameter range to the safety system; generate at least one user-defined safety parameter based on at least one user-defined safety function; provide the user-defined safety parameter to the safety system; where the safety system comprises a safety range safety monitoring function configured to: evaluating if the at least one user-defined safety parameter is within the user-defined safety range; and bringing the robot arm into a safe mode in case the user-defined safety parameter is outside the user-defined safety range.Type: ApplicationFiled: August 16, 2024Publication date: December 5, 2024Applicant: Universal Robots A/SInventors: Anders Billesø BECK, David Brandt, Jakob Schultz Ormhøj
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Publication number: 20240400542Abstract: Sulfonyl-triazole compounds and related sulfonyl-heterocycle compounds are described. The compounds can form covalent adducts with reactive nucleophilic amino acid residues, e.g., reactive tyrosines and reactive lysines, in kinases to form modified kinases and/or alter the biological activity of the kinases. Kinases targetable by the compounds include cyclin-dependent kinase 2 (CDK2), diacylglycerol kinases (DGKs), and phosphofructokinase (PFK). Pharmaceutical compositions including the compounds and methods of inhibiting kinases are also described.Type: ApplicationFiled: August 19, 2022Publication date: December 5, 2024Applicant: University of Virginia Patent FoundationInventors: Ku-Lung Hsu, Kun Yuan, Minhaj Shaikh, Xiaoding Jiang, Tao Huang, Adam Libby
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Publication number: 20240405158Abstract: A method for fabricating epitaxial light control features, without reactive ion etching or wet etching, when active layers are included. The epitaxial light control features comprise light extraction or guiding structures integrated on an epitaxial layer of a light emitting device such as a light emitting diode. The light extraction or guiding structures are fabricated on the epitaxial layer using an epitaxial lateral overgrowth (ELO) technique. The epitaxial light control features can have many different shapes and can be fabricated with standard processing techniques, making them highly manufacturable at costs similar to standard processing techniques.Type: ApplicationFiled: October 28, 2022Publication date: December 5, 2024Applicant: The Regents of the University of CaliforniaInventors: Srinivas Gandrothula, Shuji Nakamura, Steven P. DenBaars
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Publication number: 20240401099Abstract: Provided herein, among other things, is a conjugate comprising a polymerase and a nucleoside triphosphate, where the polymerase and the nucleoside triphosphate are covalently linked via a linker that comprises a cleavable linkage. A set of such conjugates, where the conjugates correspond to G, A, T (or U) and C is also provided. Methods for synthesizing a nucleic acid of a defined sequence are also provided. The conjugates can also be used for sequencing applications.Type: ApplicationFiled: December 28, 2023Publication date: December 5, 2024Applicant: The Regents of the University of CaliforniaInventors: Daniel Arlow, Sebastian Palluk
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Publication number: 20240399663Abstract: A hybrid manufacturing method and a device made thereby. The method includes: laser writing a border on a receiving surface of a substrate, the border defining an internal zone inside the border and an external zone outside the border, the border being a part of the substrate that is changed in its material properties by the laser writing; depositing a material in the internal zone, the material being deposited in an uncured state on the receiving surface, wherein a flow of the material from the internal zone towards the external zone is impeded by the border; and at least partially curing the material in the internal zone, the at least partially cured material forming a layer.Type: ApplicationFiled: September 21, 2022Publication date: December 5, 2024Applicants: Nanyang Technological University, Panasonic Factory Solutions Asia Pacific Pte. Ltd.Inventors: Cheng Yang Nicholas THAM, Daryl Chin Yew LIM, Adam Zhe Kuan LIM, Lewei HE, Chidanand HEGDE, Mun Ji LOW, Murukeshan VADAKKE MATHAM
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Publication number: 20240402354Abstract: Embeddings of spherical triangles onto a planar surface permit locations on a sphere to be represented as cells on the planar surface. Embeddings define paths based on one or more sets of great circles which can in turn be based on rotations of an icosahedron. Distances between locations as well as locations can be determined as integer values unlike conventional latitude/longitude-based systems that require floating point arithmetic. Some locations correspond to cells on different paths defined by one or more sets of great circles. Distance between two locations can be estimated as a minimum of distances associated with the cell locations on the different paths. Methods for processing data defined with respect to an origin point in three-dimensional space include establishing a set of concentric spherical shells with the origin point as their origin and establishing a discrete global grid on the concentric spherical shells.Type: ApplicationFiled: June 5, 2024Publication date: December 5, 2024Applicant: Southern Oregon UniversityInventor: Kevin Sahr
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Publication number: 20240401225Abstract: Provided are a P-type ZrCoSb-based half-Heusler single crystal alloy and a preparation method thereof. The method for preparing the P-type ZrCoSb-based half-Heusler single crystal alloy includes: subjecting alloy raw materials to smelting under a first protective atmosphere to obtain a half-Heusler polycrystalline alloy ingot, the alloy raw materials corresponding to a chemical composition of the P-type ZrCoSb-based half-Heusler single crystal alloy; and subjecting the half-Heusler polycrystalline alloy ingot to vertical Bridgman directional crystallization under a second protective atmosphere to obtain the P-type ZrCoSb-based half-Heusler single crystal alloy. The P-type ZrCoSb-based half-Heusler single crystal alloy has the chemical composition of ZrCoSb1-xSnx, x in the ZrCoSb1-xSnx being in a range of 0.1?x?0.3; and the P-type ZrCoSb-based half-Heusler single crystal alloy has an MgAgAs-type crystal structure.Type: ApplicationFiled: October 16, 2023Publication date: December 5, 2024Applicants: Dalian University of Technology, NingBo Inst. of Dalian University of TechnologyInventors: Huijun KANG, Rongchun CHEN, Tongmin WANG, Enyu GUO, Zongning CHEN, Tingju LI, Zhiqiang CAO, Yiping LU, Jinchuan JIE, Yubo ZHANG
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Publication number: 20240400585Abstract: The present invention relates to novel trityl-nitroxide radicals as polarizing agents for Dynamic Nuclear Polarization (DNP).Type: ApplicationFiled: September 12, 2022Publication date: December 5, 2024Applicants: Commissariat a l'Energie Atomique et aux Energies Alternatives, University of Iceland, Universite Grenoble AlpesInventors: Gaël DE PAEPE, Rania HARRABI, Frédéric MENTINK-VIGIER, Snorri Th. SIGURDSSON, Thomas HALBRITTER
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Publication number: 20240404653Abstract: A processing workflow centered on machine-learning algorithms that identifies a number of chemical features that can best distinguish the presence or absence of a chemical source. These chemical features are a chemical fingerprint that is unique to each source. The analysis workflow is rapid (e.g., fingerprints can be generated in minutes). The analysis workflow has wide-ranging applications such as detecting markers of pollution sources in rivers and fish tissues, forest pathogen outbreaks, and hard-to-diagnose diseases.Type: ApplicationFiled: August 12, 2024Publication date: December 5, 2024Applicant: Oregon State UniversityInventor: Gerrad Jones
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Publication number: 20240403675Abstract: Techniques for stochastic control of at least one load is provided. Electric power generators provide alternating current (AC) to a plurality of consumer premises (CP). Each CP has one or more loads configured to be electrically powered by the AC. The stochastic control is performed at each consumer premises in a distributed manner. The stochastic control is used to maintain or increase the frequency of the AC provided by an AC electrical power distribution grid when such AC frequency falls below a nominal AC frequency of the AC electrical power distribution grid.Type: ApplicationFiled: April 17, 2024Publication date: December 5, 2024Applicant: University of Central Florida Research Foundation, Inc.Inventors: Guanyu Tian, Qun Zhou Sun
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VR-BASED STANDARDIZED TRAINING SYSTEM FOR MULTI-PERSON ONLINE COOPERATED FIRST-AID NURSING OF TRAUMA
Publication number: 20240404418Abstract: The present application provides a VR-based standardized training system for multi-person online cooperated first-aid nursing of trauma, which is used for providing medical staff with an efficient and convenient-to-update and maintain standardized training environment for multi-person online cooperated first-aid nursing of trauma by introducing the VR technology, so as to significantly improve the training effect of the first aid of trauma of the medical staff.Type: ApplicationFiled: April 26, 2024Publication date: December 5, 2024Applicant: Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & TechnologyInventors: Jing CHENG, Huibing CHEN, La XIE, Yaru XIAO, Xiangping LIU, Jie WU, Zheying LI, Hui WU, Jingjing FU -
Publication number: 20240405915Abstract: An optimization-based decoder with improved performance and cyclic redundancy check is provided. An optimization problem is generated and solved. The optimization problem includes a function implementing constraints on variables. Main variables correspond to nodes of the encoding graph, including input variables corresponding to output nodes and output variables corresponding to input nodes. Ancillary variables correspond to an additional output a logical operations in the encoding graph. Constraints are configured to generate cost penalties, for instance when the main and ancillary variables of a candidate solution disagree with conditions of the encoding graph, and to correspond with the cross-entropy between each codeword symbol and the corresponding input variable. A candidate solution is obtained by solving the optimization problem, wherein the output variables in the candidate solution correspond to decoded symbols.Type: ApplicationFiled: June 5, 2024Publication date: December 5, 2024Applicant: The Royal Institution for the Advancement of Learning / McGill UniversityInventors: Huayi ZHOU, Ryan Meng Yong SEAH, Marwan JALALEDDINE, Warren Jeffrey GROSS
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Publication number: 20240398552Abstract: A nasal tissue implant for reconstruction and tissue engineering of nasal tissue in a subject includes a tissue scaffold component comprising a biocompatible polymeric material having a plurality of open pores configured to support cell growth. The tissue scaffold component conforms to a portion of the subject's nasal region and defines at least a portion of the subject's nasal anatomy. A method of making an implantable nasal tissue implant for reconstructing a portion of a nasal anatomy of a human or other animal subject is also provided that includes laser sintering or three-dimensional (3D) printing a biocompatible polymeric material to form a tissue scaffold component comprising a biocompatible polymeric material having a plurality of open pores configured to support cell growth. Again, the tissue scaffold component substantially conforms to a nasal region specific to the human or other animal subject.Type: ApplicationFiled: August 15, 2024Publication date: December 5, 2024Applicants: The Regents of The University of Michigan, Georgia Tech Research CorporationInventors: David A. ZOPF, Scott J. Hollister