Abstract: A print head comprising nested chambers for in-situ reactant formation is disclosed. The print head comprises a first chamber nested within a second chamber. The first chamber comprises a first nozzle, the second chamber comprises a second nozzle. The first nozzle is substantially coaxial with the second nozzle. A susceptor to convert electromagnetic energy to heat is within the first chamber. The susceptor comprises one or more openings extending between the upper portion and the lower portion. The susceptor may be heated by induction heating or by optical heating to vaporize a precursor substance within the first chamber. The vapor may react with a reactive gas flowing through the first chamber or expand through a nozzle into a second chamber where the vapor may react with the reactive gas, forming nanoparticles. Patterned films may be written onto a two-dimensional or three-dimensional surfaces.

Abstract: A fluid modulator includes a fluid manifold, fluid valve, and pressure/flow controller. The manifold may include a primary tee, exhaust tee, secondary tee, loop conduit, and joining tube. The valve may include a common port, normally-open output port connected to the secondary tee, and normally-closed output port connected to the primary tee. The controller may be configured to provide auxiliary fluid to the common port. In embodiments, the primary tee, exhaust tee, and secondary tee are configured with the primary tee and secondary tee situated at ends of the fluid manifold and the exhaust tee disposed therebetween. In other embodiments, the exhaust tee, the primary tee, and the secondary tee are distributed in a linear fashion with the exhaust tee and secondary tee situated at ends of the fluid manifold and the primary tee disposed therebetween. An embodiment with a single, unitary 5-port fluid manifold is also disclosed.

Abstract: The present invention provides N-acetyl derivatives of sialic acids, including N-acetyl derivatives of Neu5Ac and Neu5Gc. Methods for preparing related precursors and a variety of sialosides are also disclosed.

Abstract: A high voltage pulse generation device includes n transformer cores configuring a transformer, n being a natural number of 2 or more, each of the n transformer cores being configured to form a magnetic circuit along a first plane and to have a width in a first direction parallel to the first plane larger than a width in a second direction parallel to the first plane and perpendicular to the first direction; n primary electric circuits of the transformer connected in parallel to each other, each of the n primary electric circuits including at least one primary coil, and m pulse generation units connected in parallel to the at least one primary coil, m being a natural number equal to or more than 2; and a secondary electric circuit of the transformer including a secondary coil and connected to a pair of discharge electrodes.

Abstract: The present disclosure is generally directed to a plasma sheet source and methods of using same. The plasma sheet source includes a cylindrical electrode having a conductive cylindrical core surrounded by a dielectric material, a plurality of channels configured to direct gas from a gas inlet to the electrode, and a plasma outlet positioned below the electrode. Gas is introduced to the plasma sheet source and directed toward the electrode, which when powered by pulsed direct current, produces plasma as the gas ionizes. The produced plasma is then directed out of the plasma outlet to a specimen for treatment of the specimen. Notably, the plasma exiting the plasma outlet is in the form of a plasma sheet that is at approximately room temperature.

Abstract: A curable composite material containing nanodiamonds, denture bases and other dental prosthetics made from the composite material and methods for treating dental stomatitis using these prosthetics.

Abstract: The present disclosure belongs to the technical field of monitoring landslide mass geological disasters, and discloses a multi-state triggered system and method for remote automatic monitoring and early warning of a landslide mass. The multi-state triggered system for remote automatic monitoring and early warning of a landslide mass includes: a landslide mass monitoring module, a data preprocessing module, a communication module, a central control module, a displacement monitoring module, a stability evaluation module, an abnormality early warning module, a power supply module, a data storage module and a display update module. In the present disclosure, through the displacement monitoring module and the stability evaluation module, long-term automatic monitoring of the landslide mass can be realized, and the displacement change of the landslide mass can be grasped so as to evaluate the stability of the landslide mass.

Abstract: An internal solitary wave (ISW) early warning method for an offshore platform based on a baroclinic mode includes the following steps: S1: providing a hydrophone and a bottom-founded transmitting transducer in a sea area of an offshore platform, and acquiring an actually measured sound pressure; S2: solving a hydrodynamic equation to obtain a baroclinic mode of the sea area of the offshore platform; S3: constructing a seawater sound velocity equation according to the baroclinic mode; S4: transforming the seawater sound velocity equation to obtain a relational expression between an amplitude of the baroclinic mode and a seawater sound velocity; S5: solving, according to the actually measured sound pressure, and the relational expression between the amplitude of the baroclinic mode and the seawater sound velocity, the amplitude of the baroclinic mode with a genetic algorithm (GA); and S6: performing monitoring and early warning on an ISW.

Abstract: A thin film laminate structure, an integrated device including the same, and a method of manufacturing the thin film laminate structure are provided. The thin film laminate structure includes two or more dielectric layers, wherein at least one of the dielectric layers of the thin film laminate structure includes a compound represented by Formula 1 and having a perovskite-type crystal structure having a B/B? composition ratio different from that of a remainder of the dielectric layers: AB1-xB?xO3??<Formula 1> wherein, in Formula 1, A, B, B?, and x are the same as defined in the specification.

Abstract: A method for designing a multi-layer optical structure includes: obtaining candidate multi-layer optical structures through a sequence generator; obtaining a candidate spectrum for each candidate multi-layer optical structure; obtaining a difference between the candidate spectrum and a target spectrum; updating sequence generator parameters through reinforcement learning training and iteratively performing the obtainings and the updating in response to a first termination condition being not met; and selecting one of all obtained candidate structures to be a target multi-layer optical structure in response to the first termination condition being met. The difference between a spectrum of the target multi-layer optical structure and the target spectrum is minimized through the process. The method of the present application can perform the designs robustly and effectively.

Abstract: The present invention provides a mutant strain of Corynebacterium glutamicum with efficient expression of exogenous proteins, which can solve the technical problem of low protein expression quantity of using Corynebacterium glutamicum as an exogenous protein expression host. The mutant strain of Corynebacterium glutamicum is deposited in the China General Microbiological Culture Collection Center (CGMCC), and the deposit number is CGMCC No. 20138. The mutant strain of Corynebacterium glutamicum in the present invention, verified by the expression of exogenous proteins, shows a significantly enhanced expression of both intracellular and secreted proteins when compared with its initial strain.

Abstract: A method for making a recombinant gene includes searching a database using a nucleotide sequence of a coding region, a nucleotide sequence that encodes an amino acid sequence, or an amino acid sequence, of a gene, for one or more nucleotide sequences having homology; selecting one or more nucleotide sequences other than nucleotide sequences only derived from a genome from the selected nucleotide sequences; for ones of the selected one or more nucleotide sequences comprising an upstream or downstream nucleotide sequence, analyzing whether the upstream or downstream nucleotide sequence is a functional sequence to select one or more first functional sequences; for ones of the selected one or more nucleotide sequences comprising no upstream or downstream nucleotide sequence, analyzing whether a gene information has any description indicating a functional sequence to select one or more second functional sequences; scoring the selected functional sequences; and selecting one or more functional sequences.

Abstract: A barrier system is provided for use in reducing infections associated with post-operative surgical incision and/or a percutaneous medical device, such as a catheter, that is disposed within the surgical incision. Such a barrier system may include: a barrier device having a skin-contacting surface and a catheter-receiving surface; and an adhesive composition configured for adhering to skin, the barrier device, and/or the catheter so as to form a barrier at or adjacent to an incision in the skin where the catheter is percutaneously inserted through the skin. A tensioning anchor and associated system of two or more tensioning anchors is provided for post-operative wound closure. A method for applying and removing the barrier device and tensioning anchors is also provided.

Abstract: Described herein are devices incorporating Casimir cavities, which modify the quantum vacuum mode distribution within the cavities. The Casimir cavities can create energy differences within layers or device to drive energy from or to a portion of a layer disposed adjacent to or contiguous with the Casimir cavity by modifying the quantum vacuum mode distribution incident on one portion of the layer to be different from the quantum vacuum mode distribution incident on another portion of the layer. Additionally, Casimir cavities in which the cavity layer comprises a conductor that can be used to carry a flow of electrical power induced by the presence of the Casimir cavity.

Abstract: An F-18 labeled chiral pure derivative of hydroxyfuran, a preparation method and use thereof were provided. (4R, 5R)[18F]FAA provided by the present disclosure is a chiral pure radioactive compound, and three other chiral pure [18F]FAA structural formulae are also provided by the present disclosure. The present disclosure provides a chiral pure radioactive probe (4R, 5R)[18F]FAA, which shows unique tumor diagnostic efficiency and similar distribution to AA, and can be used for early diagnosis of tumors, pathological studies, assessment of disease progression, and evaluation for efficacy.

Abstract: A security inspection apparatus and a method of controlling the same are described. An example security inspection apparatus includes a bottom plate configured to carry an inspected object and a two-dimensional multi-input multi-output array panel, including at least one two-dimensional multi-input multi-output sub-array. Each two-dimensional multi-input multi-output sub-array includes transmitting antennas and receiving antennas arranged such that equivalent phase centers are arranged in a two-dimensional array. The security inspection apparatus includes a control circuit configured to control the transmitting antennas to transmit a detection signal in a form of an electromagnetic wave to the inspected object in a preset order, and to control the receiving antennas to receive an echo signal from the inspected object.

Abstract: Systems and methods for anomaly detection in accordance with embodiments of the invention are illustrated. One embodiment includes a method for training a system for detecting anomalous samples. The method draws data samples from a data distribution of true samples and an anomaly distribution and draws a latent sample from a latent space. The method further includes steps for training a generator to generate data samples based on the drawn data samples and the latent sample, and training a cyclic discriminator to distinguish between true data samples and reconstructed samples. A reconstructed sample is generated by the generator based on an encoding of a data sample. The method identifies a set of one or more true pairs, a set of one or more anomalous pairs, and a set of one or more generated pairs. The method trains a joint discriminator to distinguish true pairs from anomalous and generated pairs.

Abstract: The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method comprises administering to the central nervous system of an individual in need of such treatment a therapeutically effective amount of an agent capable of increasing the expression and/or activity of miR-128.

Abstract: Provided herein are non-naturally occurring, broadly reactive, pan-epitopic antigens derived from H3 influenza virus that are immunogenic and are capable of eliciting a broadly reactive immune response, such as a broadly reactive neutralizing antibody response, against H3 virus following introduction into a subject. Also provided are non-naturally, broadly reactive occurring immunogens, vaccines, virus-like particles (VLPs) and compositions comprising the immunogens and vaccines. Methods of generating an immune response in a subject by administering the immunogens, vaccines, VLPs, or compositions thereof are provided. In particular, the immunogens comprise the hemagglutinin (HA) protein of H3 influenza virus strains.

Abstract: Disclosed herein are methods and systems for transient-based decoding of neural signals. In one aspect, a device such as a brain-computer interface (BCI), includes at least one processor configured to receive a plurality of neural signals from a subject. The at least one processor can detect, from the plurality of neural signals, first neural activity unique to a first defined temporal window corresponding to an onset phase of an intended action of the subject. The at least one processor can detect, from the plurality of neural signals, second neural activity unique to a second defined temporal window, occurring after the first temporal window and corresponding to an offset phase of the intended action. The at least one processor can generate at least one output indicative of the intended action, responsive to detecting at least one of the first neural activity or the second neural activity.