Abstract: The present invention provides methods for adsorbing a protein onto a conductive solid substrate, comprising the application of an external potential to the solid substrate greater than +500 mV vs. the Ag/AgCl/Cl?SAT reference electrode, in the presence of a solution comprising the protein, wherein the solution has a pH within + 2 units of the isoelectric point of the protein, and wherein the protein adsorbs to the conductive solid substrate upon application of the external potential. Some embodiments are directed to a process of protein adsorption on a solid surface mediated by an applied potential that can be affected significantly by altering a number of variables such as protein concentration, flexibility, charge, molecular weight, pH, and charge of substrate.

Abstract: The present invention provides an apparatus and method for microdissecting a biological sample. In particular, apparatuses of the invention include a cell collecting device 100 that is operated by a pneumatic device 200. In one particular embodiment, apparatuses of the invention are used for collecting and transferring cell sample to and from cell collecting device 100.

Abstract: Provided herein are methods of decreasing leukocyte extravasation from a lymph or blood vessel into a tissue in a mammal, methods of decreasing fluid leakage from a lymph or blood vessel in a mammal in need thereof, methods of decreasing formation of atherosclerotic plaques in a mammal in need thereof, and methods of treating atherosclerosis in a mammal that include administering to the mammal an oligonucleotide that decreases Mitogen-activated protein kinase kinase kinase kinase 4 (Map4k4) mRNA expression in an endothelial cell. Also provided are methods of identifying a candidate agent useful for decreasing leukocyte extravasation or decreasing fluid leakage from a lymph or blood vessel in a mammal, and compositions containing an oligonucleotide that decreases Map4k4 mRNA expression in an endothelial cell and additional therapeutic agents.

Abstract: The present invention relates to a method for manufacturing a module type microfluidic chip comprising: (a) printing electrode patterns on a substrate using a conductive ink and inkjet printing; (b) cutting the printed electrode patterns; and (c) assembling the cut electrode patterns to manufacture the module type microfluidic paper chip. Unlike the traditional method for manufacturing printed circuit substrate using a patterning agent or device, the method of the present invention only incorporates a simple printing process using an inkjet printer, and thus patterning can be simplified and various types of chips can be manufactured depending on the assembly type of electrode patterns. Accordingly, inexpensive, economical, and highly utilizable microfluidic chips can be provided using the method of the present invention.

Abstract: Superconducting cables employ one or more superconducting tapes wound around a former. A compact superconducting cable is configured using a former having a small diameter, e.g., less than 10 millimeters. A flexible superconducting cable is configured with a former made of a flexible material. Superconducting tape conductors are wound around the former, with the superconducting layer in compression on the inside of the wind turns of the wind, to prevent irreversible damage to the superconductor. A layer of solder is on the superconducting tape(s) or solder sheaths are wound between tape conductors in each layer. The one or more solder layers or sheaths are melted to cause the solder to flow within the structure, to bond some or all of the superconducting tape conductors together and form a mechanically strong cable with an enhanced level of electrical connectivity between tapes in the cable.

Abstract: A transurethral catheter kit containing a balloon catheter and a syringe assembly adapted for inflation of the balloon, The syringe assembly includes a syringe and a nozzle incorporating a narrow bore proximal to a pressure relief valve. The narrow bore serves to resist the flow of fluid between the syringe and the balloon, thereby avoiding a rapid pressure increase in the balloon that can result in damage to tissues or premature activation of the pressure relief valve. Also provided is a method for correctly placing a transurethral balloon catheter in a patient using the kit.

Abstract: Various embodiments of the present disclosure pertain to methods of making magnetic carbon nanoribbons. Such methods generally include: (1) forming carbon nanoribbons by splitting carbon nanomaterials; and (2) associating graphene nanoribbons with magnetic materials, precursors of magnetic materials, or combinations thereof. Further embodiments of the present disclosure also include a step of reducing the precursors of magnetic materials to magnetic materials. In various embodiments, the associating occurs before, during or after the splitting of the carbon nanomaterials. In some embodiments, the methods of the present disclosure further comprise a step of (3) functionalizing the carbon nanoribbons with functionalizing agents. In more specific embodiments, the functionalizing occurs in situ during the splitting of carbon nanomaterials. In further embodiments, the carbon nanoribbons are edge-functionalized.

Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) and Toll-like receptor agonist (TLR) through a linker and a multifunctional connector group or molecule.

Abstract: The objective of the present invention is in the field of cleaning agent in particular detergents. In particular, it relates to a novel detergent formulation for an automatic dishwashing. The formulation provides excellent cleaning and finishing; it is environmentally friendlier than traditional compositions and allows for a more energy efficient automatic dishwashing process.

Abstract: Disclosed herein are compositions and methods for the treatment and/or protection of airway cells and/or tissue from damage due to injury to the lungs or complications of underlying respiratory, cardiovascular or infectious diseases, or any combination thereof.

Abstract: The present invention provides a Hemoglobin A1c-specific aptamer and a Hemoglobin-specific aptamer. The aptamers were selected in vitro using SELEX and a microfluidic chip system. The aptamers established low free energy, thus were more stable than conventional antibodies. The high specificity of the aptamers to Hemoglobin A1c or Hemoglobin allows them to be effectively used in diagnosis of diabetes and/or anemia.

Abstract: Cost, electronic circuitry limitations, and communication channel behaviour yield communication systems with strict bandwidth constraints. Hence, maximally utilizing available bandwidth is crucial, for example in wireless networks, to supporting ever increasing numbers of users and their demands for increased data volumes, low latency, and high download speeds. Accordingly, it would be beneficial for such networks to support variable bandwidth allocations such that smaller frequency sub-bands are allocated to users, as their number increases, but the individual users/nodes insert more data-carrying signals in order to compensate pensate for the loss of operating bandwidth arising from the accommodation of more users. It would further be beneficial for transmitters and receivers according to embodiments of such a network architecture to be based upon low cost design methodologies allowing their deployment within a wide range of applications including high volume, low cost consumer electronics for example.

Abstract: Methods for the preparation of mono- and bis-end-functionalized ?-conjugated polymers. In the methods, chalcogens are selectively installed at the polymer terminus or termini.

Abstract: Disclosed herein are a spectrum sensing apparatus and method for a cognitive radio (CCR) network in a non-Gaussian noise environment and an FC apparatus and CCR system using the same. The cooperative cognitive radio (CCR) system includes M cognitive radios (CRs), and a fusion center (FC). Each of the M CRs samples a baseband signal obtained by down-converting a radio signal detected in the corresponding frequency spectrum, and generates spectrum sensing information (SSI) indicating that a PU signal has been detected based on the results of the sampling. The FC determines a joint threshold ?FC that can maximize an expected average throughput of a secondary user (SU) signal in a given communication environment including a maximum interference condition, calculates a joint test statistic from received M pieces of SSI, and determines whether the PU signal is present by comparing the calculated joint test statistic with the joint threshold.

Abstract: Disclosed is a method to construct a device that includes a plurality of nanowires (NWs) each having a core and at least one shell. The method includes providing a plurality of radially encoded NWs where each shell contains one of a plurality of different shell materials; and differentiating individual ones of the NWs from one another by selectively removing or not removing shell material within areas to be electrically coupled to individual ones of a plurality of mesowires (MWs). Also disclosed is a nanowire array that contains radially encoded NWs, and a computer program product useful in forming a nanowire array.

Abstract: This disclosure provides systems and methods for sequencing nucleic acids using nucleotide analogues and translocation of tags from incorporated nucleotide analogues through a nanopore. In aspects, this disclosure is related to composition, method, and system for sequencing a nucleic acid using tag molecules and detection of translocation through a nanopore of tags released from incorporation of the molecule.

Abstract: A pneumatic driving module is for mounting on and driving a vehicle. The vehicle includes at least one wheel that includes a rim. The pneumatic driving module includes a storage tank, an air delivery unit and an air-driving mechanism. The storage tank is for storing compressed air therein. The air delivery unit includes a tube fluidly communicating with the storage tank for discharging the compressed air stored in the storage tank. The air-driving mechanism fluidly communicates with the tube, and is configured to be mounted directly to the wheel for providing dynamic energy associated with the compressed air to the rim to drive rotation of the wheel.

Abstract: In some embodiments, the present disclosure pertains to methods of capturing a gas from an environment by associating the environment (e.g., a pressurized environment) with a porous carbon material that comprises a plurality of pores and a plurality of nucleophilic moieties. In some embodiments, the associating results in sorption of gas components (e.g., CO2 or H2S) to the porous carbon materials. In some embodiments, the methods of the present disclosure also include a step of releasing captured gas components from porous carbon materials. In some embodiments, the releasing occurs without any heating steps by decreasing environmental pressure. In some embodiments, the methods of the present disclosure also include a step of disposing released gas components and reusing porous carbon materials. Additional embodiments of the present disclosure pertain to porous carbon materials that are used for gas capture.

Abstract: A method for three-dimensional data acquisition, adapted to acquire three-dimensional data of an object, includes the following steps. A laser light is projected onto a plurality of regions on the surface of the object so as to form a plurality of features within each of the regions. For each of the regions, the object and the features are captured from a first direction and a second direction simultaneously so as to generate a first object image corresponding to the first direction and a second object image corresponding to the second direction. For each of the regions, the first object image and the second object image are processed so as to obtain the two-dimensional coordinates of the features therein. The three-dimensional data of the object is obtained according to the two-dimensional data of the features in the first object image and the second object image corresponding to each of the regions.

Abstract: This disclosure provides a method for determining if a patient is likely to, or not likely to, experience ovarian cancer utilizing SP17 as a biomarker. It also provides methods and therapies to treat patients identified as at risk for ovarian cancer or alternatively, as identified as having a poorer prognosis.