Patents Assigned to University
  • Publication number: 20150112048
    Abstract: The present invention provides novel ginsenoside derivative compounds and the use thereof in protection against ischemia/reperfusion injury.
    Type: Application
    Filed: October 17, 2013
    Publication date: April 23, 2015
    Applicant: Macau University of Science and Tehnology
    Inventors: Jingrong WANG, Pei LUO, Hua ZHOU, Wai In CHAN, Liang LIU, Zhihong JIANG
  • Publication number: 20150107599
    Abstract: Post vitrectomy head stabilization devices are disclosed. The post vitrectomy head stabilization devices include a head strap connected to a head support rod, a chin strap connected to a chin support rod and a torso belt connected to the head support rod and connected to the chin support rod. The post vitrectomy head stabilization devices of the present disclosure advantageously allow a user to maintain a face down head position while the user's torso adopts an upright position such as when the user is standing, walking or seated.
    Type: Application
    Filed: October 18, 2013
    Publication date: April 23, 2015
    Applicant: Saint Louis University
    Inventor: Michael T. Railey
  • Publication number: 20150111764
    Abstract: Micropatterns of glycan-bearing brush polymers generated by the initiation of oligomerization of acrylate and methacrylate monomers from thiol-terminated surfaces. Chain lengths are controlled in situ by varying exposure time, and these multivalent glycan scaffolds detect glycan binding proteins at sub-micromolar concentrations.
    Type: Application
    Filed: October 22, 2013
    Publication date: April 23, 2015
    Applicant: New York University
    Inventors: Adam B. Braunschweig, Shudan Bian, Sylwia Zieba
  • Publication number: 20150111492
    Abstract: An integrated contactless signal transfer apparatus makes use of the rule of filter design to transfer signal from a chip to the transmission lines of a PCB. The integrated contactless signal transfer apparatus includes a substrate, a chip disposed on the substrate, a first resonator unit disposed on the chip for receiving a first signal with a first frequency generated from the chip, a PCB positioned at a distance opposite to the substrate, and a second resonator unit disposed on the PCB. The first signal passes through the first resonator unit to generate a contactless coupling between the first and second resonator units, so the second resonator unit generates a second signal. The second signal has a second frequency substantially equal to the first frequency.
    Type: Application
    Filed: November 29, 2013
    Publication date: April 23, 2015
    Applicant: National Chiao Tung University
    Inventors: Shyh-Jong CHUNG, Hsiao-Ning WANG
  • Publication number: 20150108673
    Abstract: A micro-contact imprinting apparatus for transferring patterns of a stamp to a substrate.
    Type: Application
    Filed: October 18, 2013
    Publication date: April 23, 2015
    Applicant: The Chinese University of Hong Kong
    Inventors: Shih-Chi Chen, Jianwei Chen, Jiyi Cheng
  • Publication number: 20150111858
    Abstract: A prodrug can have a structure of Formula 10 or derivative thereof or stereoisomer thereof or pharmaceutically acceptable salt thereof. The prodrug can be included in a pharmaceutical composition for use in treatment of fungus, cancer, dermatitis, superficial mycoses; inflammation, tinea pedis, tinea cruris, and tinea corporis, Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis, candidiasis (moniliasis), Candida albicans, tinea (pityriasis) vesicolor, Malassezia furfur, acute myeloid leukemia, acute lymphoid leukemia, chronic myelogenous leukemia, lymphoma or multiple myeloma.
    Type: Application
    Filed: October 21, 2013
    Publication date: April 23, 2015
    Applicant: The University of Kansas
    Inventors: Mehmet Tanol, Scott J. Weir
  • Publication number: 20150112652
    Abstract: This invention provides a computational approach to identifying potential antibacterial drug targets based on a genome sequence and its annotation. Starting from a fully sequenced genome, open reading frame assignments are made which determine the metabolic genotype for the organism. The metabolic genotype, and more specifically its stoichiometric matrix, are analyzed using flux balance analysis to assess the effects of genetic deletions on the fitness of the organism and its ability to produce essential biomolecules required for growth.
    Type: Application
    Filed: December 13, 2013
    Publication date: April 23, 2015
    Applicant: The Regents of the University of California
    Inventor: Bernhard O. Palsson
  • Publication number: 20150112626
    Abstract: A method for verifying manufacturing measurements used for predicting outputs by virtual analysis instruments in a factory, which has production equipment and a virtual analysis instrument, comprises steps: using model-building data of the virtual analysis instrument to build a verification model via a PCA method, and obtaining control limits of the verification model; inputting a plurality of pre-verification measurements into the verification model to calculate verification statistic, and using the verification statistic and the control limits to exclude at least one failure value from the pre-verification measurements to generate the validated measurements; and finally inputting the validated measurements into the virtual analysis instrument for predicting the outputs to determine that the manufacturing measurements are valid, and using the production equipment to undertake production according to predictions of the virtual analysis instrument.
    Type: Application
    Filed: December 17, 2013
    Publication date: April 23, 2015
    Applicant: National Tsing Hua University
    Inventor: Jia-Lin Liu
  • Publication number: 20150111226
    Abstract: The present invention provides a method of peptide histochemical diagnosis to detect the peptide binding protein in the cancer tissue. This peptide binding specifically to tumor cells is linked to the dextran coated iron oxide nanoparticle. The peptide linked dextran coated iron oxide nanoparticle can be used to bind to the formalin-fixed and paraffin-embedded tumor surgical specimens, and the method of present invention can be used to evaluate the efficacy of peptide-targeted chemotherapy for treatment of cancer patients.
    Type: Application
    Filed: January 27, 2014
    Publication date: April 23, 2015
    Applicant: National Taiwan University
    Inventors: Chin-Tarng Lin, Han-Chung Wu
  • Publication number: 20150110862
    Abstract: Sweet gum (Liquidambar styraciflua L., family Hamamelidaceae) fruit extract was discovered to possess potent activities against multiple targets of the PI3K (phosphatidylinositide 3-kinase) pathway, especially the PI3K/Akt and mTOR pathways. At a very low concentration of 1.85 ?g/ml (IC50), sweet gun extract showed the ability of simultaneously blocking the pathways of PI3K/Akt (upstream), mTOR (mammalian target of rapamycin) (downstream), as well as its downstream protein products S6K and S6. It was also able to block 5-HETE, a lipoxygenase product that contributes to inflammation and activation of PI3K/Akt. The sweet gum fruit extract was prepared with 50% methanol (47:1; raw to extract) and concentrated to an organic fraction (210:1 raw to extract) referred as LIS-100 via reverse-phase column chromatography using a bioassay directed fractionation approach.
    Type: Application
    Filed: January 6, 2015
    Publication date: April 23, 2015
    Applicants: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Board of Regents
    Inventors: Zhijun Liu, Peiying Yang, Robert A. Newman
  • Publication number: 20150110704
    Abstract: The present invention provides a method for preparing carbon nanotube fibers with improved spinning properties using a surfactant and carbon nanotube fibers prepared by the method. According to the method for preparing carbon nanotube fibers of the present invention, the addition of a surfactant during the preparation of carbon nanotubes interrupts and delays the agglomeration of catalyst particles, which reduces the size of the catalyst particles and uniformly disperses the catalyst particles that play a key role in the formation of carbon nanotube fibers, thus increasing the strength and conductivity of carbon nanotube fibers and improving the spinning properties. While convention methods prepare carbon nanotube fibers by injecting a catalytic material for the synthesis of carbon nanotubes in a high-pressure supercritical state to be uniformly dispersed, the present invention uses a dispersant and thus does not require the injection in a high-pressure supercritical state.
    Type: Application
    Filed: December 26, 2012
    Publication date: April 23, 2015
    Applicant: Soongsil University Research Consortium Techno- Park
    Inventors: Young Jin Jeong, Jun Young Song, So Young Kim, So Ra Yoon, Yeon Su Jung
  • Publication number: 20150110750
    Abstract: The present invention relates to the field of autologous fibroblasts. More specifically, the present invention provides methods and compositions comprising autologous fibroblasts and uses thereof to alter skin identity. In certain embodiments, volar fibroblasts can be expanded for the ability to induce volar skin at the stump site in amputees. In other embodiments, fibroblasts from haired scalp can be expanded to ameliorate alopecias.
    Type: Application
    Filed: April 30, 2013
    Publication date: April 23, 2015
    Applicants: The John Hopkins University, The Government of the United States of America, as represented by the Secretary of the Army
    Inventors: Luis Andres Garza, Sewon Kang, Jon H. Meyerle
  • Publication number: 20150110807
    Abstract: Polypeptides that bind to DC-SIGN and/or its homologues and methods for using such peptides for the treatment of various disorders are described. DC-SIGN and its homologues are receptors that bind IgG antibodies or Fc fragments and mediate intravenous immunoglobulin (IVIG)-related reversal of inflammation associated with various immune disorders.
    Type: Application
    Filed: December 10, 2012
    Publication date: April 23, 2015
    Applicants: The Rockefeller University, Sloan-Kettering Institute for Cancer Research
    Inventors: Jeffrey Ravetch, Andrew Pincetic, Ping Wang, Sam Danishefsky
  • Publication number: 20150108982
    Abstract: A pulse restoration circuit includes: a voltage restorator configured to include an OP amplifier and input an input voltage to an input terminal of the OP amplifier; a rising time restorator configured to be connected to the other input terminal of the OP amplifier; and a falling time restorator configured to be connected to an output terminal of the OP amplifier, whereby it is possible to improve a reduction in performance of the medical image electronics transmitting an analog signal via the cable and a PET detector of a PET-MRI convergence system among the medical image electronics by correcting a distortion phenomenon of an output signal depending on a cable length into the original signal using the pulse restoration circuit.
    Type: Application
    Filed: December 5, 2012
    Publication date: April 23, 2015
    Applicant: Industry-University Cooperation Foundation Sogang University
    Inventors: Yong Choi, Jihoon Kang, Kyubom Kim
  • Patent number: 9011817
    Abstract: Embodiments of the present disclosure provide for compounds and methods of making compounds such as those shown in FIGS. 1.1A and 1.1B having formula 2, 3, 4, 5, 11, and 12 and formula 2?, 4?, and 11?, as well as uses for the compounds for imaging, and the like.
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: April 21, 2015
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Mohammad Namavari, Sanjiv Sam Gambhir, Beverly S. Mitchell
  • Patent number: 9011866
    Abstract: An immunotherapeutic strategy is disclosed that combines antigen-encoding DNA vaccine compositions combined with siRNA directed to pro-apoptotic genes, primarily Bak and Bax, the products of which are known to lead to apoptotic death. Gene gun delivery (particle bombardment) of siRNA specific for Bak and/or Bax to antigen-expressing DCs prolongs the lives of such DCs and lead to enhanced generation of antigen-specific CD8+ T cell-mediated immune responses in vivo. Similarly, antigen-loaded DC's transfected with siRNA targeting Bak and/or Bax serve as improved immunogens and tumor immunotherapeutic agents.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: April 21, 2015
    Assignee: The Johns Hopkins University
    Inventors: Tzyy-Choou Wu, Chien-Fu Hung
  • Patent number: 9012368
    Abstract: A system and method for systematically generating potential metal-organic framework (MOFs) structures given an input library of building blocks is provided herein. One or more material properties of the potential MOFs are evaluated using computational simulations. A range of material properties (surface area, pore volume, pore size distribution, powder x-ray diffraction pattern, methane adsorption capability, and the like) can be estimated, and in doing so, illuminate unidentified structure-property relationships that may only have been recognized by taking a global view of MOF structures. In addition to identifying structure-property relationships, this systematic approach to identify the MOFs of interest is used to identify one or more MOFs that may be useful for high pressure methane storage.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: April 21, 2015
    Assignee: Northwestern University
    Inventors: Christopher E. Wilmer, Michael Leaf, Randall Q. Snurr, Omar K. Farha, Joseph T. Hupp
  • Patent number: 9012471
    Abstract: The present invention provides, inter alia, dihydropyridone compounds and compositions, including analogs of a vesicular monoamine transporter type 2 (VMAT2) antagonist. The present invention also provides methods of using such compounds/analogs for modulating glucose levels, and/or preventing, treating, or ameliorating the effects of diabetes and hyper-glycemia.
    Type: Grant
    Filed: April 10, 2009
    Date of Patent: April 21, 2015
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Paul Harris, Antonella Maffei, Yuli Xie, Donald Landry
  • Patent number: 9012127
    Abstract: The invention includes a novel light-activated polymerizable composition, wherein reversible crosslinks may be converted into irreversible crosslinks using a fully controllable physical and/or chemical process. The invention further includes methods of photofixing a light sensitive material or patterning an article comprising a light sensitive material.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: April 21, 2015
    Assignee: The Regents of the University of Colorado, a Body Corporate
    Inventors: Christopher Bowman, Christopher J. Kloxin, Brian J. Adzima
  • Patent number: 9012134
    Abstract: The invention provides methods of isolating CD127lo/? immunosuppressive regulatory T cells which can be greatly enriched for FoxP3, methods of expanding the isolated cells, pharmaceutical compositions of such cells, and methods of their use in the treatment of autoimmune and other immune system mediated disorders.
    Type: Grant
    Filed: May 31, 2007
    Date of Patent: April 21, 2015
    Assignee: The Regents of the University of California
    Inventors: Jeffrey A. Bluestone, Weihong Liu, Amy Putnam