Abstract: A laser irradiation device for irradiating laser to a tissue includes: a decrease form determination unit configured to determine a decrease form of laser power according to a laser irradiation time; a decrease rate determination unit configured to determine a decrease rate of the determined decrease form; a laser light source unit configured to emit laser in the determined decrease form and the determined decrease rate; and a laser irradiation unit configured to receive laser emitted from the laser light source unit and irradiate the received laser. A constant photoreaction can be induced by constantly maintaining a temperature in a site to be irradiated with laser.

Abstract: A set of target peptides are presented by HLA class I molecules on the surface of hepatocellular carcinoma (HCC) ceils and/or esophageal cancer cells. They are envisioned to among other things (a) stimulate an immune response to the proliferative disease, e.g., HCC and/or esophageal cancer, (b) function as immunotherapeutics in adoptive T-cell therapy or as a vaccine, (c) facilitate antibody recognition of tumor boundaries in surgical pathology samples, (d) act as biomarkers for early detection and/or diagnosis of the disease, and (e) act as targets in the generation anti-body-like molecules which recognize the target-peptide/MHC complex.

Abstract: Certain embodiments are directed to methods and compositions for preventing or treating bacterial infections. In certain embodiments the compositions comprise thioredoxin inhibitors, and/or thioredoxin-like inhibitors.

Abstract: This invention relates to a creel structure integrated on the fiber placement head of the automated placement equipment, comprising: fiber placement head mounting base, fixed yarn box component fixed and mounted on fiber placement head mounting base, and revolving yarn box component mounted on fiber placement head mounting base, the said revolving yarn box component is coupled with the fiber placement head mounting base through revolving shaft. This creel structure can avoid intervention that arise due to equipment maintenance and spindle replacement, making equipment maintenance and spindle replacement more convenient and swift.

Abstract: The invention provides pluripotent cells that are used therapeutically for regenerating tissues but avoid rejection by subjects that receive them. In particular, the invention provides hypo-immunogenic pluripotent cells that avoid host immune rejection. The cells lack major immune antigens that trigger immune responses and are engineered to avoid phagocytic endocytosis. The invention further provides universally acceptable “off-the-shelf” pluripotent cells and derivatives thereof for generating or regenerating specific tissues and organs.

Abstract: An assembled self-recovery circular concrete-filled steel-tube composite joint includes a circular steel-tube column and H-shaped steel beams, where steel bars penetrate through the circular steel-tube column; the circular steel-tube column includes an upper steel-tube column section, a central inserted-connection column section and a lower steel-tube column section; the upper steel-tube column section is connected to the central inserted-connection column section through an upper sleeve connector, and the central inserted-connection column section is connected to the lower steel-tube column section through a lower sleeve connector; and the H-shaped steel beams are connected to the circular steel-tube column through the upper sleeve connector and the lower sleeve connector. According to the assembled self-recovery circular concrete-filled steel-tube composite joint, all members are machined in a factory and are connected on site through bolts.

Abstract: Modified alginates are described herein along with hydrogels comprising the same. A modified alginate may be prepared by reacting alginate and an aromatic compound (e.g., an aromatic amine) and/or pH sensitive compound. The modified alginates, hydrogels, and/or methods described herein may be used to coat and/or encapsulate at least a portion of a bioactive substance, optionally for oral delivery in humans and other animals.

Abstract: A method and system for recommending online content based upon the predictive value of reviews provided by third party reviewers correlated to the identity of those reviewers. The correlated data is used to predict how a target user would rate an unrated item, and to make recommendations to the target user.

Abstract: Methods are disclosed herein for producing human hepatocytes from human induced pluripotent stem cells. Also provided are transgenic rats for the expansion of human hepatocytes, such as those produced using the methods disclosed herein.

Abstract: The present disclosure discloses a manufacturing method for a high-resolution array organic film, and use thereof The high-resolution array organic film manufacturing method performs, by means of electrochemical deposition, polymerization of electrically active monomers on a high-resolution display screen array substrate to deposit and form a high-resolution array organic film. Also disclosed is a use of the manufactured high-resolution array organic film in manufacturing of OLED display screens. By employing electrochemical deposition to deposit the high-resolution array film on the high-resolution array substrate, the present disclosure provides a high-resolution film forming technique having simple operation, a low cost, film controllability, and precision up to 10 ?M.

Abstract: Embodiments described herein improve fuel economy by controlling a vehicle powertrain based on a predicted vehicle velocity. The vehicle velocity is predicted based on vehicle-to-vehicle data when a prediction horizon is a longer prediction horizon and the vehicle velocity is predicted based on historical drive cycle data when the prediction horizon is a shorter prediction horizon. A time duration of the shorter prediction horizon is shorter than the time duration of the longer prediction horizon. A plurality of drive cycles are established for both the longer and the shorter prediction horizons using a neural network. A shorter prediction horizon drive cycle uses nonlinear autoregressive exogenous model neural networks and the longer prediction horizon drive cycle uses two layer feedforward neural networks. The predicted vehicle velocity is determined from a similar drive cycle of the plurality of drive cycles of either the shorter and/or the longer prediction horizon drive cycles.

Abstract: This invention relates to a fiber placement head integrating tow converging mechanism, comprising: fiber placement head mounting base; fixed yarn box component and revolving yarn box component arranged at the side end of the fiber placement head mounting base, tow passage formed between the revolving mounting face of the said fiber placement head mounting base and the relative face of the revolving yarn box component; tow conveying components respectively arranged on the sides of the fixed yarn box component and revolving yarn box component; and tow converging mechanism for guiding and converging tows conveyed by tow conveying components. Through appropriate design of guide pulley and tow passage, the fiber placement head realizes the guiding and converging of multiple tows, avoiding intervening among the tows.

Abstract: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of tumor amongst all human cancers due to late diagnosis and resistant to treatment with chemotherapy and radiation. Preclinical and clinical studies have revealed that ErbB family for example epidermal growth factor receptor (EGFR) is a validated molecular target for pancreatic cancer prevention and therapy. The ErbB signaling cascade is regulated by a member of the ADAM (a disintegrin and metalloprotease) family, namely ADAM17, by enzymatic cleavage of precursor ligands into soluble cytokines and growth factors. Mouse genetic studies have demonstrated that ADAM17 is required for PDAC development. In this study, we evaluated the anti-tumor effects of A9(B8) IgG—the first specific ‘human and mouse cross-reactive’ ADAM17 inhibitory antibody on pancreatic malignant transformation. We found that inhibition of ADAM17 with A9(B8) IgG efficiently suppressed the shedding of ADAM17 substrates both in vivo and in vitro.

Abstract: Method to generate microfractures by chemical reaction in low carbonate mineral content shale reservoirs in which sulfate acid or persulfate compound (such as ammonium persulfate ((NH4)2S2O8) at a relatively high content) injected into conventional fracturing fluid can react with shale carbonate components resulting in the precipitation reaction of gypsum crystal (CaSO4.2H2O) to occur because an insoluble calcium sulfate (CaSO4) solid is formed. It has been found that expansion stress generated by rapid crystallization in the shale nanoscale pore space can intensively crack shale rocks without additional energy input. Not only does this lead to the formation of much denser secondary microfracture networks, it also can increase SRV by the micrometer-scale gypsum crystals prohibiting these secondary microfracture networks from closure under a normal stress, thereby, improve the efficiency of hydraulic fracturing and hydrocarbon production.

Abstract: A method and system is disclosed for identifying a location of an event in a power distribution network. The method includes receiving voltage and current flowing downstream and upstream of the distribution feeder from at least two distribution-level phasor measurement units (PMUs) installed on a distribution feeder in the power distribution network; calculating changes in forward nodal voltages along the distribution feeder using measurements from at least one PMU of the at least two distribution-level PMUs; calculating changes in backward nodal voltages along the distribution feeder using the measurements from another PMU of the at least two distribution-level PMUs; comparing the calculated changes in the forward nodal voltages to the calculated changes in the backward nodal voltages; and determining the location of the event based on the comparison of the calculated changes of the forward nodal voltages to the calculated changes backward nodal voltages.

Abstract: A method of making Co3O4 nanorods by thermal decomposition of a cobalt salt is described. A method of using Co3O4 nanorods as an electrocatalyst component to a porous carbon electrode is also described. The carbon electrode may be made of carbonized filter paper. Together, this carbon-supported Co3O4 electrode may be used for water electrolysis.

Abstract: Cross-linked polymer resins and related salts, solvates, tautomers or stereoisomers are described herein. The cross-linked polymer resins may comprise monomer units of N,N-diallyl aminoalkylphosphonate, a hydrophobic pendant, a tetraallylpiperazinium cross-linker, and sulfur dioxide. A method for producing the cross-linked polymer resins is described. The cross-linked polymer resins may be used as adsorbent materials for the removal of heavy metal ions and contaminant dyes from aqueous solutions. Used cross-linked polymer resins may be removed from solution, cleaned, and reused while maintaining adsorption capacity.

Abstract: The invention relates to methods of evaluating the quality of a batch of an herbal composition, the method comprising subjecting a test batch of the herbal composition to one or more biological analysis methods and comparing the results derived from the test batch to the results of a known batch of herbal composition which has a known in vivo effect.

Abstract: A structure, method, and computer program product for a diabetes control system provides, but is not limited thereto, the following: open-loop or closed-loop control of diabetes that adapts to individual physiologic characteristics and to the behavioral profile of each person. An exemplary aspect to this adaptation is biosystem (patient or subject) observation and modular control. Consequently, established is the fundamental architecture and the principal components for a modular system, which may include algorithmic observers of patients' behavior and metabolic state, as well as interacting control modules responsible for basal rate, insulin boluses, and hypoglycemia prevention.

Abstract: A microfluidic photoreactor for treating excess bilirubin in blood, having: a microfluidic channel module; an illumination module comprising one or more illumination sources disposed about the microfluidic channel module and configured to illuminate blood passing through at least one microfluidic channel of the microfluidic channel module; and a heat exchanger module coupled to the at least one microfluidic channel module, wherein the heat exchanger module is configured to extract heat from the at least one microfluidic channel. A system including a microfluidic photoreactor and a method of treating excess bilirubin in blood.