Abstract: The present invention relates to a rotating catheter tip for optical coherence tomography based on the use of an optical fiber that does not rotate, that is enclosed in a catheter, which has a tip rotates under the influence of a fluid drive system to redirect light from the fiber to a surrounding vessel and the light reflected or backscattered from the vessel back to the optical fiber.

Abstract: Disclosed is a silicon-carbon composite for a negative active material of a lithium secondary battery, including carbon nanofibers and silicon particles, wherein the silicon particles are coated with amorphous silica. In the silicon-carbon composite of the invention, silicon is provided in the form of a composite with carbon fibers and the surface of silicon particles is coated with amorphous silica, thereby reducing volume expansion upon lithium ion insertion and exhibiting superior ionic conductivity and electrical conductivity to thus maintain high capacity, and also, amorphous silica-coated silicon is positioned inside the carbon fibers having a one-dimensional structure, thus ensuring a large specific surface area and a stable composite structure.

Abstract: A light collector includes a light guide having a refractive index larger than a refractive index of air and a reflecting surface configured to reflect light output from a conic surface of the light guide back to the light guide. The light guide is made of transparent material through which light passes. The light guide has an entering portion from which light enters and an exiting portion from which the light exits. The light guide has a circular cone shape and has a cross-sectional area that decreases in a direction from the entering portion to the exiting portion.

Abstract: Various embodiments disclose devices and methods for fabricating microporous particulate filters with regularly spaced pores wherein sheet membrane substrates are exposed to energetic particle radiation through a mask and the damaged regions removed in a suitable developer. The required depth of field is achieved by using energetic particles to minimize diffraction and an energetic particle source with suitably small diameter.

Abstract: The present invention relates to the discovery of (SNPs) significantly associated with Huntington's disease (HD). The present invention utilizes RNA silencing technology (e.g. RNAi) against such SNPs optimally combined with select additional SNP targeting silencing agents, thereby resulting in an effective treatment of significantly-sized patient populations. Silencing agents having enhanced discriminatory properties are also featured.

Abstract: Provided are effective and highly safe agents, medicaments and the like for ameliorating various disorders caused by brain hypofunction. Also provided is a preventing or ameliorating agent for brain hypofunction containing N-acetyl-D-mannosamine, a pharmaceutical composition for preventing, ameliorating or treating disorders due to brain hypofunction, containing an effective amount of N-acetyl-D-mannosamine and a pharmaceutically acceptable carrier, and a food comprising N-acetyl-D-mannosamine added thereto.

Abstract: The present invention relates to peptides having one or more stable, internally-constrained HBS ?-helices, where the peptide is capable of interacting with Ras and related proteins.

Abstract: A boxing game machine includes a punch bag, a frame, a rocker, a catch, a latch and a spring. The rocker is pivotally connected to the frame between an idle position and an active position. The punch bag is secured to an end of the rocker. The catch is secured to another end of the cocker and formed with a radial edge. The latch is movably supported on the frame and formed with an edge for sliding into contact with radial edge of the catch so that the latch engages with the catch. The spring biases the latch into engagement with the catch to keep the rocker in the idle position.

Abstract: The present invention provides a composition comprising a hyaluronic acid derivative having a crosslinking group(s) and a hydrophilic polysaccharide derivative having a hydrophobic group(s), wherein the hyaluronic acid derivative having a crosslinking group(s) is prepared by crosslinkage formation reaction in hyaluronic acid or a derivative thereof having a crosslinkable group(s) in the presence of the hydrophilic polysaccharide derivative wherein the hydrophilic polysaccharide derivative may have a crosslinkable group(s).

Abstract: A vacuum sealed directional microphone and methods for fabricating said vacuum sealed directional microphone. A vacuum sealed directional microphone includes a rocking structure coupled to two vacuum sealed diaphragms which are responsible for collecting incoming sound and deforming under sound pressure. The rocking structure's resistance to bending aids in reducing the deflection of each diaphragm under large atmospheric pressure. Furthermore, the rocking structure exhibits little resistance about its pivot thereby enabling it to freely rotate in response to small pressure gradients characteristic of sound. The backside cavities of such a device can be fabricated without the use of the deep reactive ion etch step thereby allowing such a microphone to be fabricated with a CMOS compatible process.

Abstract: The invention discloses an erythropoietin receptor modified electrode, which is a glassy carbon electrode with erythropoietin receptor as recognition element fixed onto the electrode surface via ZnO sol-gel. The modified electrode can be prepared easily, and its performance is stable. After 50-day storage in the dark at 4° C., its response current remained approximately 77% of the original value. An electrochemical biosensor using this modified electrode as working electrode, a platinum electrode as counter electrode, a saturated calomel electrode as reference electrode, and 2 mmol/L K3[Fe(CN)6]—K4[Fe(CN)6]phosphate buffer as the test base solution, can detect erythropoietin (EPO) and/or recombinant human erythropoietin (rhEPO) in a fast, specific, and sensitive manner, with a linear range of 5 pg/L-500 ng/L and a limit of detection of 0.5 pg/L. In particular, according to peak potential differences, the biosensor allows accurate discrimination of EPO and rhEPO.

Abstract: The present invention provides methods of treating a ?-arrestin2 mediated and/or GPR120 mediated response in a subject. The ?-arrestin2 mediated and/or GPR120 mediated response can be inflammation, including diabetes, inflammation associated with obesity and obesity. The methods can comprise administering to a subject a therapeutically effective amount of a compound predicted to bind a ?-arrestin2 molecule and/or GPR120, wherein the compound selectively activates a ?-arrestin2-dependent signaling pathway of GPR120.

Abstract: Provided are a compound of Formula 1 and an organic light-emitting device including the compound of Formula 1: The compounds of Formula 1 are particularly useful as fluorescent dopants in the emission layer of the organic light-emitting device.

Abstract: Methods are provided for making ceramic preforms having two-dimensional interconnected channels therein. The methods include (i) positioning a sacrificial material having a selected profile within a bed of ceramic powder; (ii) compacting the bed of ceramic powder to form a compacted mass; (iii) heating the compacted mass to thermally transform the sacrificial materials into a fluid without cracking the compacted mass; and (iv) removing the fluid from the compacted mass, thereby leaving a two-dimensional network of interconnected channels having the selected profile of the sacrificial material within the compacted mass. Ceramic preforms are also provided which include a compacted mass of ceramic powder and two-dimensional interconnected channels therein.

Abstract: In one aspect, the invention relates to substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: An image processing device acquiring pseudo projection data by calculation when a virtual metallic body having a predetermined X-ray absorption coefficient is set in a photographic region of X-ray CT photography in a pseudo manner based on projection data, and the image processing device reconstructing the pseudo projection data to acquire pseudo CT image data. The image processing device acquires luminance (virtual metallic body luminance) of a virtual metallic body in the pseudo CT image data, and specifies a position of a metal equivalent region having luminance corresponding to the virtual metallic body luminance in normal CT image data. The image processing device acquires correction projection data by performing correction processing to the luminance of the metal equivalent region in the normal projection data, and the image processing device reconstructs the correction projection data to acquire correction CT image data.

Abstract: Data that are stored in cells of a multi-bit-per cell memory, according to a systematic or non-systematic ECC, are read and corrected (systematic ECC) or recovered (non-systematic ECC) in accordance with estimated probabilities that one or more of the read bits are erroneous. In one method of the present invention, the estimates are a priori. In another method of the present invention, the estimates are based only on aspects of the read bits that include significances or bit pages of the read bits. In a third method of the present invention, the estimates are based only on values of the read bits. Not all the estimates are equal.

Abstract: A method of dynamic resource allocation for a virtual machine cluster is to calculate the resource usage weight of the respective virtual machine, the resource usage weight of the respective physical machine, and the average resource usage weight of the physical machines, to pick the physical machine with the greatest resource usage weight as the migration source machine, to pick the physical machine with the least resource usage weight as the migration object machine, and to move the virtual machine in the migration source machine with the resource usage weight thereof being closest to the migration difference value to the migration object machine to achieve the effect of load balancing.

Abstract: A portable human balance training device for improving the human proprioceptive system, athletic performance, athletic speed, athletic agility, athletic vertical leap, athletic eye/hand coordination, spatial awareness, left/right brain organization and increasing the muscular development of a user. The balancing device has an elongated suspended support structure spanning the length of the device. The balancing device also has an end support structure at each end for suspending and stabilizing the support structure. A flexible line is mounted to the end supports and spans the length of the support structure. The user places all or part of their body weight on the suspended support band and attempts to balance.

Abstract: The present invention relates generally to dynamic and/or adjustable support devices, methods of providing dynamic and/or adjustable support to target tissues, and kits comprising these devices. These devices may have particular utility in providing support to the urethra. The dynamic support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one expandable member capable of assuming an unexpanded configuration and an expanded configuration. The adjustable support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one shape-changing portion that is capable of assuming first and second configurations, each with different shapes. Additionally, the dynamic support devices may comprise features of the adjustable support devices, and vice versa.