Abstract: Methods, structures, devices and systems are disclosed for implementing compact (e.g., nanoscale) coaxial lasers with coaxial cavity geometries which can be used to construct various coaxial cavity lasers that can operate in single mode, at room-temperature, and produce continuous-wave lasing. The described laser systems can also operate at low-temperatures, and provide thresholdless lasing using a spectrally broadband semiconductor gain medium. The cavity of the compact lasers includes a central metal core and a hollow ring surrounding the central metal core, formed within a housing with an open terminal and a closed terminal. The open terminal is positioned to both receive pump light and output laser light, and the closed terminal includes a metal cap that encloses the central metal rod and one side of the hollow ring. The described nano cavities also include a ring-shaped gain medium section, and ring-shaped lower and upper plug sections.

Abstract: This patent generally relates to developing treatment plans for use in external beam radiation therapy, and more particularly to a method, a system and a computer readable media that contains programming for the development of external beam radiation therapy treatment plans. Embodiments of the invention include (1) automatically setting beam angles based on a beam angle automation algorithm, (2) judiciously designing planning structures and (3) automatically adjusting the objectives of the objective function based on a parameter automation algorithm.

Abstract: The present invention relates to a life attenuated Bordetella pertussis vaccine which is deficient for tracheal cytotoxin (TCT), pertussis toxin (PTX), and dermonecrotic toxin (DNT) for prophylaxis or treatment of an allergen-driven airway pathology.

Abstract: The present invention relates to affinity biosensing using polarization of light scattering of aggregated noble metallic nanostructures to determine concentration of an analyte in a test sample. This new sensing system utilizes the changes in polarized plasmonic scattering from nanostructures as the nanostructures aggregate due to binding of the analyte to a binding partner attached to the surface of the metallic nanostructure.

Abstract: Three resonance-based universal power converter topologies are disclosed. One includes a partially resonant parallel L-C link and incorporates intermediate cross-over switching circuits between the link stage and each of the input and output stages (which are constructed using unidirectional switches), thereby permitting the partially resonant circuit to be operated bi-directionally. A second includes a partially resonant series LC link in parallel with the input and output networks. A third includes a partially resonant series LC link in series between the input and output networks. The input and output networks can be formed from either bidirectional switches or a combination of unidirectional switches and intermediate cross-over switching circuits, permitting the partially resonant circuit to be operated bi-directionally.

Abstract: A BOTDA system that combined optical pulse coding techniques and coherent detection includes a narrow linewidth laser, two polarization-maintaining couplers, microwave generator, two electro-optic modulators (EOMs), fiber under test, an optical circulator, a 3 dB coupler, a polarization scrambler, a pulse generator, a balance photodetector, an electrical spectrum analyzer, digital signal processing unit and a frequency shifter. The optical pulse coding techniques and coherent detection are simultaneously used in the invented system, which can be enhance the signal-to-noise ration (SNR), the measuring accuracy and the sensing distance of BOTDA. Moreover, the proposed system has the capacity of break interrogation.

Abstract: The present invention relates to a nisin derivative comprising amino acid substitutions in the peptide sequence encoding the hinge region of the protein, wherein the derivative exhibits an increased anti-microbial activity.

Abstract: A method of calibrating a first threshold voltage that is a reference of X-ray detection for each unit cell of a plurality of unit cells of an X-ray detector may comprise detecting an X-ray by using a plurality of second threshold voltages for each of a plurality of X-rays having spectra at different energy levels; determining a correspondence relationship between energies having a maximum intensity in the spectra of X-rays and third threshold voltages at which a maximum number of photons having a same energy intensity are detected; and/or calibrating the first threshold voltage based on the determined correspondence relationship.

Abstract: Provided are a novel fullerene derivative which can adsorb quickly and efficiently an allergen which may cause a pollen allergy without releasing the allergen again, does not contain a metal or the like which may cause a harmful effect to a human body, and is easily applicable, impregnable, or chemically bondable onto surface of various materials: and a process for producing the same. The fullerene derivative is characterized in that a halogen group and many hydroxyl groups are bonded directly to a fullerene nucleus. In the case that the halogen group is chlorine, the fullerene derivative can be synthesized by a partial hydroxylation of a chlorinated fullerene or a partial chlorination of a hydroxylated fullerene.

Abstract: A Nisin derivative or variant, comprising an amino acid substitution at amino acid position 29 in the amino acid sequence. The Nisin derivative exhibits enhanced antimicrobial activity when compared to wild type Nisin. The Nisin derivative has an application as a natural food additive and as a therapeutic agent.

Abstract: A solid electrolyte including a layered metal oxide represented by the formula (1), (La1-xAx)(Sr1-yBy)3(Co1-zCz)3O10-???(1) [wherein A represents a rare earth element other than La; B represents Mg, Ca, or Ba; C represents Ti, V, Cr, or Mn; 0?x<1, 0?y<1, 0?z<1; and ? represents an oxygen deficiency amount].

Abstract: Disclosed are optical sensing devices and methods for detecting samples using the same. The optical sensing device comprises a source unit configured to generate a polychromatic light beam containing p-polarized and s-polarized components; an interferometric unit configured to split the light beam into a probe beam passing a first path and a reference beam passing a second path and to recombine the probe beam output from the first path and the reference beam output from the second path; a sensing unit disposed in the first path to introduce a first SPR effect associated with a target sample to the probe beam; and a detection unit configured to detect target sample characteristics by obtaining an intensity spectrum of the recombined light beam. The introduction of a polychromatic light source in the optical sensing device increases the detection dynamic range and the detection sensitivity.

Abstract: A scanning apparatus, is used to effect multiple images of a tumor in which a contrast agent has been localized as a detectable marker over a selected time to map the change in the imaged marker. The rate of change in the imaged marker and/or contrast intensity of the dyed tissues is used to assess tumor aggressiveness and as an early predictor of response to cancer therapy. In particular, following the marking of tumor or cancerous tissues by the initial localization of an imageable contrast agent, the rate of change in the volume and/or area of the imaged marker is used to provide an indication of tumor interstitial fluid pressure (TIFP).

Abstract: A hybrid cement clinker incorporates specific ranges of clinker phases and falls within specific modulus values as set forth and described in this document.

Abstract: The present invention relates to methods and compositions for enhancing folding and stability of biological molecules. In particular, the present invention relates to methods and compositions for identifying biological molecules with enhanced stability. The present invention further relates to host cells that confer enhanced stability to biological molecules expressed therein.

Abstract: A controllable lighting system may include a plurality of light source groups, a group controller for each light source group, a master controller, and a network communication system. Each group controller may be configured to control the light sources in its light source group based on a group control command. The master controller may be configured to receive a master control command relating to the light sources and to issue a group control command to each of the group controllers that collectively effectuate compliance with the master control command. The network communication system may be configured to communicate the group control commands from the master controller to the group controllers.

Abstract: The present invention relates to a focus-adjustable device and a system thereof, wherein the focus-adjustable device is fabricated by forming a single closed flow channel in the internal of a transparent substrate, so as to make the substrate and the single closed flow channel together form a specific lens structure similar to the Fresnel lens. In the present invention, when a light illuminates on one side of the substrate, the light would be concentrated at a specific focus point distancing from the other side of the substrate after being deflected by the specific lens structure. Moreover, a fluid having a specific refractive index can be filled into the single closed flow channel by a flow channel opening, so as to carry out the purpose of adjusting the focus of the specific lens structure; or to make the light parallelly pass through the specific lens structure without any deflection.

Abstract: Method of ablating the surface of a substrate including providing a dry substrate and an electrolyte source, ablating the surface of the dry substrate to at least partially remove a native oxide layer, and immersing the ablated dry substrate in the electrolyte source, in which the dry substrate is ablated prior to being introduced into the electrolyte source. Also provided is a method of ablating the surface of a substrate that includes providing a dry substrate and an electrolyte, depositing a portion of the electrolyte on the substrate at a thickness of less than 10 microns and ablating the surface of the substrate with the electrolyte applied thereon. System for use in the ablation of the surface of a substrate are also provided.

Abstract: Methods, compositions and kits for determining the developmental potential of one or more embryos or pluripotent cells and/or the presence of chromosomal abnormalities in one or more embryos or pluripotent cells are provided. These methods, compositions and kits find use in identifying embryos and oocytes in vitro that are most useful in treating infertility in humans.

Abstract: In some embodiments, the present invention provides amphiphilic nanosheets that comprise lamellar crystals with at least two regions: a first hydrophilic region, and a second hydrophobic region. In some embodiments, the amphiphilic nanosheets of the present invention also comprise a plurality of functional groups that are appended to the lamellar crystals. In some embodiments, the functional groups are hydrophobic functional groups that are appended to the second region of the lamellar crystals. In some embodiments, the lamellar crystals comprise ?-zirconium phosphates. Additional embodiments of the present invention pertain to methods of making the aforementioned amphiphilic nanosheets. Such methods generally comprise appending one or more functional groups to a stack of lamellar crystals; and exfoliating the stack of lamellar crystals for form the amphiphilic nanosheets.