Abstract: Provided are a PCR method and a PCR kit each of which has higher detection accuracy and is more convenient. A PCR method of the present invention subjects a sample to a PCR reaction, the sample containing: a primer set including a first primer and a second primer; a template amplified by the primer set; a first probe which loses at least one bulge structure in a case where a double strand is formed by the first probe and the first primer and which forms the at least one bulge structure by being dissociated from the double strand formed by the first probe and the first primer; and a bulge structure-binding molecule which emits a signal by binding to the at least one bulge structure.

Abstract: The present invention provides a method for authenticating distributed peripherals on a computer network using an array of physically unclonable functions (PUF). As each PUF is unique, each PUF is able to generate a plurality of challenge response pairs that are unique to that PUF. The integrated circuits of the PUF comprise a plurality of cells, where a parameter (such as a voltage) of each cell may be measured (possibly averaged over many readings). The plurality of cells in the PUF may be arranged in a one, two or more dimensional matrix. A protocol based on an addressable PUF generator (APG) allows the protection of a network having distributed peripherals such as Internet of things (IoT), smart phones, lap top and desk top computers, or ID cards. This protection does not require the storage of a database of passwords, or secret keys. and thereby is immune to traditional database hacking attacks.

Abstract: The present application provides solvent-free methods for decarboxylation of amino acids via imine formation with a ketone, enone, enal, aldehyde co-reagent or combination thereof, under heated conditions, with optional recovery of the co-reagent and/or co-reagent byproduct.

Abstract: The invention is directed to utilization of a series of cross-linked 1,4-benzenediamine-co-alkyldiamine polymers and the use of the polymers to remove mercury from a hydrocarbon in fluid form.

Abstract: The invention provides a compound of formula I: or a salt thereof, wherein R1, R2, R3, R4 and ring A have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as anti-cancer agents.

Abstract: An imaging system uses polarized light to illuminate the target and then uses a polarization filter to remove the light that is reflected from the target without modification. The target can include one or more anisotropic objects that scatter the light and alter the polarization state of the reflected light and causing it to be selectively transmitted to the imaging device which can record the transmitted light through the filter. The illuminating light can be circularly polarized and the filter can remove the circularly polarized light. The target can include asymmetric nanoparticles, such as nanorods that alter the amplitude or phase of the scattered light enabling pass through the filter to be detected by the imaging device.

Abstract: Disclosed are proteinaceous molecules and their use in conditions associated with PKC-? overexpression, such as cancer. More particularly, the present invention discloses proteinaceous molecules and their use in altering at least one of (i) formation; (ii) proliferation; (iii) maintenance; (iv) epithelial to mesenchymal cell transition; or (v) mesenchymal to epithelial cell transition of a PKC-? overexpressing cell.

Abstract: An object of the present invention is to provide, as a simple method, a surface nitriding treatment method of a titanium material, forming a hardened nitrided layer excellent in abrasion resistance on the surface of a titanium material in a shorter time. In order to achieve the object, the present invention adopts a surface nitriding treatment method of a titanium material, wherein a hardened nitrided layer is formed on the surface of the titanium material, by blowing nitrogen gas at a flow rate of 10 L/min or more to the surface of the titanium material while the titanium material is being heated to 800° C. to 1000° C. in an inert gas atmosphere.

Abstract: A mixture for an injectable scaffold may include a self-assembling core and an additive. The additive may include an angiogenic agent, a small molecule drug, and/or an anti-inflammatory agent. The scaffold can be applied to sites where bone growth is desired.

Abstract: A method to coat oxide-based color pigments with an ultrasound-assisted coating of nanofiber or other nanostructures in order to enhance heat-fastness and color performance to said color pigments is presented. In particular, the present invention provides a method to coat oxide-based color pigments with nano-coating materials, including but not limited to, alumina and/or silica at different dosage levels, with nanospike, nanoneedle, nanoplate, and/or nanoflower morphology towards enhancing the heat-fastness and color performance of said color pigments.

Abstract: A method of automatically detecting microaneurysm based on multi-sieving convolutional neural network (CNN), includes the following steps of: A1), partitioning an image to be detected using random fern and obtaining an auxiliary channel image of the image according to a first partition result; and A2), inputting the auxiliary channel image obtained from step A1) and the image to a multi-sieving CNN training model to perform a detection and obtaining a microaneurysm detection result of the image. The process of establishing the training model includes: B1), using a current microaneurysm diagnostic report as samples and partitioning a lesion image in the microaneurysm diagnostic report using the random fern, and establishing the auxiliary channel image according to a second partition result; B2), comparing the obtained auxiliary channel image with a lesion-marked image of pixels, clarifying the samples according to a comparing result and performing the multi-sieving CNN training.

Abstract: An auxiliary portable photographing device for use in a mobile phone includes an image collection module, a data transmission module and a second power module; the image collection module includes a lens optical unit, an imaging unit and a collection controller connected together; the lens optical unit adopts a lens system of a multistage barrel; the imaging unit adopts a CMOS system; the data transmission module includes an AD converter, a register and a transmission controller connected together; the interface is detachably connected with the connector to achieve detachable connection. The image data collection method performs photographing by the lens optical unit and imaging unit, and the picture photographed is transmitted to the mobile phone to be processed, optimized and displayed. The photographing device is light and portable as compared to conventional portable cameras, and provides better image data as compared to cameras built in the mobile phones.

Abstract: The present invention disclosed a method for improving the adsorption capacity of a fixed bed and its application in organic waste gas treatment field. The steps are: (1) adsorption: organic waste gas is passed through the adsorption column containing the adsorbent to allow the organic waste to be adsorbed; when VOCs concentration at the outlet end of the adsorption column reached a preset value, the adsorption is halted; (2) desorption: adsorbent that has absorbed VOCs was desorbed by water vapor of 110° C. or higher, or hot nitrogen of 150° C. or higher; the desorbed VOCs enter into a condenser and is recovered in liquid state; (3) pre-adsorption of water: spray water inside the adsorption column after the desorption to adjust the water content of the adsorbent to 8-35%, no other treatment is necessary before the next batch of VOCs adsorption.

Abstract: A peristaltic micropump includes one or more flexible channels configured to transfer one or more pumped fluids, and an actuator configured to engage the one or more flexible channels and rotate about a central axis. The actuator includes a plurality of rolling elements and a driving element configured such that the driving element operably rotates about the central axis and each rolling element operably rolls about a respective axis that is not parallel to the central axis. The plurality of rolling elements is disposed between the one or more flexible channels and the driving element. The driving element includes a cage configured to capture the plurality of rolling elements such that the plurality of rolling elements is located at different radii from a center of the cage.

Abstract: The present disclosure relates to 5G or pre-5G communication systems that support higher data rates after 4G communication systems such as the LTE system. In the future, high-mobility terminals and low-mobility terminals will coexist in the massive connectivity environment of a mobile communication system. In such an environment, there is proposed a method of performing random access in different ways depending on the type of a terminal. More specifically, a method for a terminal may include: determining the mobility type of the terminal; and transmitting one of random access packets of different classes to the base station according to the determined mobility type.

Abstract: An integrated system for detecting safety and/or efficacy issues related to potential drug compounds by combining tissue maturation, imaging and electrophysiology measurements, at high throughput, with high signal to noise ratio. Testing includes cardiotoxicity screening, drug screening, and screening for cardiogenic factors via on-line physiological measurements.

Abstract: The present invention relates to compositions and methods for detecting motor neuron-specific miRNAs in a population of cells or subject. More particularly, the invention relates to detecting motor neuron-specific miRNAs to detect and treat motor neuron diseases associated with dysregulation of motor neuron-specific miRNAs, such as Amyotrophic Lateral Sclerosis (ALS).

Abstract: Aspects of the disclosure provide a method and system for power amplifier characterization and digital predistortion. The method includes receiving a test signal including K samples with a sampling rate fS, generating a synthetic test signal including the test signal and a sequence of (N?1) delayed versions of the test signal, generating an under-sampled signal including M samples by sampling, at a sampling rate fS/N, an output signal of a device-under-test (DUT) with the synthetic test signal as an input of the DUT, the M samples of the under-sampled signal including N segments each including K/N samples, and generating a reconstructed signal including the M samples of the under-sampled signal.

Abstract: The present invention provides proteins/genes, which are essential for survival, and consequently, for virulence of Streptococcus pneumoniae in vivo, and thus are ideal vaccine candidates for a vaccine preparation against pneumococcal infection. Further, also antibodies against said protein(s) are included in the invention.

Abstract: Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.