Abstract: A programmable logic circuit architecture using resistive memory elements. The proposed circuit architecture uses the conventional island-based Field Programmable Gate Array (FPGA) architecture, but with novel integration of CMOS-compatible resistive memory elements that can be programmed efficiently. In the proposed architecture, the programmable interconnects of FPGA are redesigned to use only resistive memory elements and metal wires. Then, the interconnects can be entirely fabricated over logic blocks to save area while keeping their architectural functions unchanged, and the programming transistors can be shared among resistive memory elements to save area. Finally, on-demand buffer insertion is proposed as the buffering solution to achieve more speedup.

Abstract: The present invention relates to a method for a method for predicting the development of renal dysfunction in a subject following physical trauma, hypotension, sepsis and/or septic shock syndrome, wherein the method comprises the steps of: —a. determining the level of an anti-inflammatory cytokine present in a sample taken from the subject after physical trauma, after a hypotensive event, after sepsis, and/or after septic shock syndrome; b. predicting the development in the subject of renal dysfunction on the basis of the level of an anti-inflammatory cytokine determined in step a).

Abstract: Pleckstrin homology domain binding compounds, pharmaceutical compositions including such compounds, and methods for their use are described herein.

Abstract: The present invention relates to compounds and methods for the prevention or treatment of infections by negative strand RNA viruses, such as influenza virus and measles virus, wherein said compounds delay or inhibit viral replication by modulating the level or activity of a polypeptide involved in the synthesis or degradation of sphingosine-1-phosphate (S1P) in a cell, tissue, or subject. The methods involve administration of one or more compounds which modulate the level of gene expression, where the gene encodes a polypeptide involved in regulating the metabolic level of S1P, or modulate the level or activity of a polypeptide involved in regulating the metabolic level of S1P, such as sphingosine kinase (SK) and S1P lyase (SPL). Exemplary methods are directed towards reducing the level of SW by reducing the level or activity of one or more SKs, increasing the level or activity of one or more SPLs, or a combination of both steps.

Abstract: Organometallic compounds, organic light-emitting devices, and lighting devices employing the same are provided. The organometallic compound has a chemical structure represented by formula (I) or (II): wherein n is 1 or 2; each R1 is independent and can be hydrogen, C1-8 alkyl, C1-8 alkoxy, C5-10 aryl, or C2-8 heteroaryl; each R2 is independent and can be hydrogen, C1-8 fluoroalkyl, or C1-8 alkyl; A is N, or CH; B is N, or CH; D is N, or C—R3, wherein R3 is H, or C1-8 alkyl; and R1 is not hydrogen when R2 is hydrogen.

Abstract: A wideband driver amplifier with embedded passive filtering and gain peaking is described. The wideband driver amplifier comprises a voltage to current circuit, a passive band-selection filter, and a current to voltage circuit. The driver amplifier features an Embedded CLC-Ladder band-selection filter and thereby immune to process variations.

Abstract: It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial, for example, to tissues in regions of low oxygen tension. This discovery provides useful treatments to regulate a subject's blood pressure and blood flow, for example, by the administration of nitrite salts. Provided herein are methods of administering a pharmaceutically-acceptable nitrite salt to a subject, for treating, preventing or ameliorating a condition selected from: (a) ischemia-reperfusion injury (e.g., hepatic or cardiac or brain ischemia-reperfusion injury); (b) pulmonary hypertension (e.g., neonatal pulmonary hypertension); or (c) cerebral artery vasospasm.

Abstract: Methods, compositions and kits for determining the developmental potential of one or more embryos or pluripotent cells and/or the presence of chromosomal abnormalities in one or more embryos or pluripotent cells are provided. These methods, compositions and kits find use in identifying embryos and oocytes in vitro that are most useful in treating infertility in humans.

Abstract: Plasmonic graphene is fabricated using thermally assisted self-assembly of plasmonic nanostructure on graphene. Silver nanostructures were deposited on graphene as an example.

Abstract: A wireless transmitter for resolving gain mismatch of TV band is disclosed. In one embodiment, a wireless transmitter comprises a two-stage 14-path harmonic-rejection mixer to manage harmonic rejection ratio in lower sub-bands, and a two-stage 6-path harmonic-rejection mixer to manage harmonic rejection ratio in upper sub-bands. The gain mismatch is resolved by selecting gain ratios of the first and the second stage of the two-stage 14-path harmonic-rejection mixer and the two-stage 6-path harmonic-rejection mixer.

Abstract: This invention relates to asphalt compositions. More specifically, this invention relates to asphalt compositions including asphalt, heavy oil ash, and sulfur. The invention provides a heavy oil ash asphalt composition that includes a base asphalt, sulfur, and heavy oil ash resulting in improved properties, as well as a method of making the composition. The heavy oil asphalt compositions can be used for asphalt based roofing compositions, damp-proofing compositions, and water proofing materials.

Abstract: A patient safety system (PSS) (100) uses optical tracking in a linear accelerator treatment room to prevent gross setup errors. A patient (150) undergoes a computed tomography (CT) treatment-simulation scan while a CT ball bearing (BB) is on patient's surface. The CT BB is replaced with an infrared reflective marker (IRRM) (160) before radiotherapy treatment starts. Coordinates of the CT BB relative to an isocenter of the treatment room are used as reference for tracking. The coordinate system of an optical tracking system is converted to a coordinate system of the treatment room. The PSS evaluates setup accuracy for a radiotherapy session by comparing real-time position of the single IRRM determined by the optical tracking technology with a predicted reference position, and displays results on a graphical user interface. The PSS stops radiation when a deviation between real-time coordinates and predicted coordinates of the IRRM (160) exceeds a predefined threshold.

Abstract: A broadband connection structure is disclosed. The broadband connection structure includes a carrier and a chip. The carrier includes a first resonator. The chip includes a second resonator and configured on the carrier using a flip-chip method. The first resonator is connected to the second resonator via a magnetic field and an electric field existing therebetween to transmit a broadband signal between the carrier and the chip. A broadband connection method is also disclosed.

Abstract: The present invention provides a method of SNP detection by using gene detection in bead-based microfluidics comprising following steps: (a) preparing a microbead with a duplex DNA; (b) inserting a dye into the duplex DNA; (c) delivering the microbead into a microchannel with a temperature gradient region; (d) heating the temperature gradient region to denature the duplex DNA; (e) monitoring a fluorescence intensity of the duplex DNA during the step (d) to obtain a melting curve; and (f) determining the SNP by a melting curve analysis method; wherein the duplex DNA is synthesized by a target single-strand DNA and an allele-specific probe. Furthermore, the present invention offers a temperature gradient region to enhance the measurement accuracy. The continuous-flow mechanism in this region is validated and optimized.

Abstract: Systems and methods for high and ultra-high vacuum physical vapor deposition with in-situ magnetic field are disclosed herein. An exemplary method for depositing a film in an evacuated vacuum chamber can include introducing a sample into the vacuum chamber. The sample can be rotated. A magnetic field can be applied that rotates synchronously with the rotating sample. Atoms can be deposited onto the sample while the sample is rotating with the magnetic field to deposit a film while the magnetic field induces magnetic anisotropy in the film.

Abstract: A metal air flow battery includes an electrochemical reaction unit and an oxygen exchange unit. The electrochemical reaction unit includes an anode electrode, a cathode electrode, and an ionic conductive membrane between the anode and the cathode, an anode electrolyte, and a cathode electrolyte. The oxygen exchange unit contacts the cathode electrolyte with oxygen separate from the electrochemical reaction unit. At least one pump is provided for pumping cathode electrolyte between the electrochemical reaction unit and the oxygen exchange unit. A method for producing an electrical current is also disclosed.

Abstract: Disclosed is a method and system for prediction of an optimized crystal structure using an evolutionary algorithm that includes inputting characterization information of a chemical structure and input parameters, generating a first generation of crystal structures from the characterization information using symmetrical initialization, optimizing the chemical structure of the first generation of crystal structures according to the input parameters, inputting the optimized first generation of crystal structures into a niching algorithm, producing a child group of crystal structures from the parent group of crystal structures using a variation operator, and adding the child group of crystal structures to an optimal group of crystal structures to form a next generation, with the niching algorithm selecting an optimal group of crystal structures and a parent group of crystal structures from the first generation of crystal structures, with an antiseed created for population diversity and every structure produced by

Abstract: Release base papers with improved surface properties and more efficient manufacturing potential are made using cellulose nanofibrils (CNF) along with high freeness, less refined pulp. Release papers serve as the backing for common adhesive labels, for industrial film coatings, and also for certain food processing uses. The CNF may be added to the furnish and processed to paper, or the CNF may be added as a coating onto a partially dried web of paper. The CNF may optionally be combined with a starch and a starch crosslinker.

Abstract: The present invention provides methods of treating and pharmaceutical compositions useful for treating a mood disorder or depressive symptoms associated with pain, inducing analgesia and treating pain in a subject by administering a pharmaceutically effective amount of an agent capable of one or more of increasing GluA1 level, expression, concentration, or biological activity, increasing calcium permeable AMPA (? amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor (CPAR) level, expression, concentration, or biological activity or potentiating a CPAR current. The agent may be an AMPA potentiator or ampakine. The agent may increase AMPA receptor currents by slowing the deactivation of open channels and may be, for instance, 2-pyrrolidinone, 4-[2-(phenylsulfonylamino)ethylthio]-2,6-difluorophenoxyacetamide (PEPA) or LY451646. The agent may also be a protein, RNA or DNA product.

Abstract: The present invention relates to a composition containing a fruit extract of Lonicera caerulea L. var. edulis as an active ingredient for the prevention and treatment of ischemic cerebrovascular disease. The fruit extract of Lonicera caerulea L. var. edulis according to the present invention has a nerve cell-protecting effect, thereby remarkably reducing neurobehavioral impairments and infarct volume due to ischemic cerebrovascular disease. Therefore, it can be provided as a pharmaceutical composition for the prevention or treatment of ischemic cerebrovascular disease, and as a health food for the prevention or improvement of ischemic cerebrovascular disease.