Abstract: A replacement knee implant has a femoral implant and a tibial implant, each of which are inset in a bone surface. The tibial implant is generally elongated with one end rounded and an opposite end conforming to the shape of the tibia, and is made of a metal alloy or a ceramic. The upper surface is dished while the lower surface is planar and can be parallel or sloped relative to the upper surface, and can have a keel for fixation. The femoral implant for implementation in a femoral condyle is rounded such that, when implemented, the femoral implant is flush at the anterior and posterior sides and protruding away from the femur between the anterior and posterior ends. The femoral implant can have an elongated keel for extending into the femur, and can be made from a highly cross-linked polyethylene.

Abstract: Devices and methods for blocking signal transmission through neural tissue. One step of a method includes placing a therapy delivery device into electrical communication with the neural tissue. The therapy delivery device includes an electrode contact having a high charge capacity material. A multi-phase direct current (DC) can be applied to the neural tissue without damaging the neural tissue. The multi-phase DC includes a cathodic DC phase and anodic DC phase that collectively produce a neural block and reduce the charge delivered by the therapy delivery device. The DC delivery can be combined with high frequency alternating current (HFAC) block to produce a system that provides effective, safe, long term block without inducing an onset response.

Abstract: One embodiment includes an image acquisition circuit that accesses a pre-treatment and a post-treatment image of a region of tissue demonstrating non-small cell lung cancer (NSCLC), a segmentation and registration circuit that annotates the tumor represented in the images, and that registers the pre-treatment image with the post-treatment image; a feature extraction circuit that selects a set of pre-treatment and a set of post-treatment quantitative vessel tortuosity (QVT) features from the registered image; a delta-QVT circuit that generates a set of delta-QVT features by computing a difference between the set of post-treatment QVT features and the set of pre-treatment QVT features; and a classification circuit that generates a probability that the region of tissue will respond to immunotherapy based on the difference, and that classifies the region of tissue as a responder or non-responder. Embodiments may generate an immunotherapy treatment plan based on the classification.

Abstract: An isolated protein that is highly abundant in the seed of wheat varieties with desirable breadmaking qualities is provided. Associated promoters and promoter active fragments are also provided. Further provided are plants or plant parts with improved or enhanced breadmaking properties, and methods of producing such plants, wherein the abundance of the isolated protein is increased or enhanced. Such plants and/or plant parts may be used in the production of plant products, for example bread and read products.

Abstract: Disclosed are a method for transferring data in a wireless communication system that supports device-to-device communication, and an apparatus therefor. Specifically, a method for performing, by a device, data transfer in a wireless communication system that supports device-to-device communication, comprises the steps of: broadcasting, at a first sub-carrier, a ready-to-forward (RTF) signal for advertising that the device holds data to transfer; receiving, at a second sub-carrier, a forward-request (FR) signal for requesting transfer of the data from another device; and broadcasting the data after a predetermined time, wherein the first sub-carrier and the second sub-carrier are determined on the basis of sequence numbers of the data, respectively.

Abstract: Embodiments herein relate to a membrane bioreactor for strengthening membrane fouling control and method thereof. The embodiments may solve problems associated with existing techniques in the field of water treatment. The membrane bioreactor may include a reactor wall, a membrane element, a collecting pipe, a water collecting pipe, a vacuum table, a suction pump, a cleaning unit, an air compressor, an aeration pipe, an aeration head, an inlet pipe, and a drain pipe. The existing techniques related to membrane fouling control has problems such as complexity to operate, difficulties to clean online, and uses of chemicals, which may cause secondary pollution. The embodiments relate to a device that includes a set of automatic mechanical transmission units.

Abstract: A method for preparing a chitosan complex film comprises: (1) reacting polyvinyl alcohol-124 with butanedioic anhydride to obtain a modified polyvinyl alcohol; (2) formulating the modified polyvinyl alcohol-124 into a 0.4 wt % aqueous solution, then adding the aqueous solution containing 0.4 wt % of modified polyvinyl alcohol-124 dropwise into an acetic acid solution at a concentration of 0.4 wt % chitosan to obtain a mixed solution; (3) adjusting the pH value of the mixed solution with a 0.01 wt % NaOH solution to pH 5.5, and removing surface bubbles after standing for one hour to obtain a casting solution; (4) pouring the casting solution into a culture dish, placing the culture dish into an oven at 60° C. and drying to a constant weight to obtain the chitosan complex film. The materials used in the method are inexpensive, and the reaction is not complicated, so the cost of the product is not high.

Abstract: Starch spherulites are produced by debranching of amylopectin-containing starch into short linear ?-1,4-linked glucans (e.g., short-chain amylose, SCA). The debranched linear glucans are directly converted into spherulites by heating the debranched starch mixture followed by cooling and crystallization to form well-developed spherulites. The spherulites exhibit controlled enzyme digestibility.

Abstract: An optical waveguide detector is provided, which includes: a silicon waveguide layer and a germanium waveguide layer. The germanium waveguide layer includes a first heavily germanium-doped area and a germanium-undoped area. A first surface of the germanium waveguide layer includes a surface of the first heavily germanium-doped area, and the first surface is a surface of the germanium waveguide layer away from the silicon waveguide layer in the first direction. A width of the first heavily germanium-doped area is less than or equal to half a width of the first surface, and a thickness of the first heavily germanium-doped area is greater than or equal to 5 nm and less than or equal to 200 nm. According to embodiments, a bandwidth of the optical waveguide detector can be effectively increased.

Abstract: A hybrid solar cell includes a photovoltaic (PV) cell having an upper grid and lower contact plate with an anode and cathode region in between. A thermoelectric (TE) cell has a top and bottom segmented connector layer with TE elements having pairs of n-doped elements and p-doped elements connected together electrically in series and thermally in parallel by segments of the top or bottom segmented connector layer. An electrically insulating and thermally conducting layer is between the plate and the TE cell. A direct electrical connection is between the cathode region provided by the upper grid or lower plate and segments contacting the n-doped elements, and a direct electrical connection is between the anode region provided by the grid or plate and segments contacting the p-doped elements for the PV cell to power the TE cell and the TE cell to provide active cooling for the PV cell.

Abstract: An electrolyte for Li-ion and other secondary electrochemical cells includes an FSI anion and at least one of methyltriethylphosphonium; trimethylisobutylphosphonium; methyltributylphosphonium; and trihexyltetradecylphosphonium. The electrolyte uniquely enables stable cell cycling even when water is present in the electrolyte at levels as high as 5000 ppm. Methyltriethylphosphonium and trimethylisobutylphosphonium-containing electrolytes are particularly effective in this water-stabilizing capacity.

Abstract: This invention discloses uses for etonogestrel in preparing anti-prostate cancer products. This invention provides uses for etonogestrel in preparing anti-prostate cancer products. From carrying out cancer drug repositioning for the FDA- and CFDA-approved drug etonogestrel, experiments for this invention show, based on screening of non-anti-cancer drugs for various cancer cell lines (tissue types) and mutation sites, that etonogestrel has a new use as an anti-prostate cancer medication, thus achieving a new purpose for an old drug.

Abstract: Disclosed herein are anti-CD47 antibody molecules, their manufacture and use in treating disorders associated with CD47 expression, for example, certain hematological cancers and solid tumors.

Abstract: The present disclosure relates to a microwave reforming apparatus for gas reforming, and provides a new technology of converting carbon dioxide which is a main greenhouse gas generated during combustion, pyrolysis/gasification, and operation of fossil fuels, methane, and dispersions thereof into high-quality fuels. A microwave reforming apparatus according to the present disclosure uses a carbon receptor and thus can solve the conventional problem of price of catalyst and also enables compactification of a device, rapid startup and response time in several seconds, and application of various kinds of product gases including polymer hydrocarbon. Also, the microwave reforming apparatus according to the present disclosure uses its own internal reaction heat at the time of reforming and thus can maintain the optimum operating conditions for a wide range of flow rate and gas properties.

Abstract: In some aspects, the present disclosure provides compositions comprising an N4-based MMC ligand, a cell targeting group, and a fluorophore or a therapeutic compound comprising a formula: wherein the variables are as defined herein. In some embodiments, these compositions may be used in the imaging techniques or in the treatment of a disease or disorder such as cancer.

Abstract: A gallium nitride (GaN) based light emitting diode (LED), wherein light is extracted through a nitrogen face (N-face) of the LED and a surface of the N-face is roughened into one or more hexagonal shaped cones. The roughened surface reduces light reflections occurring repeatedly inside the LED, and thus extracts more light out of the LED. The surface of the N-face is roughened by an anisotropic etching, which may comprise a dry etching or a photo-enhanced chemical (PEC) etching.

Abstract: Compounds of formula (I) having 1-sulfonamido-4-aryloxy as a basic backbone. A preliminary activity test showed that the compounds provide excellent interference of a binding of Nrf2 by Keap1, thereby activating Nrf2. The compounds have a potential anti-inflammatory activity and can be used to treat a plurality of inflammation-associated diseases, including chronic obstructive pulmonary disease (COPD), Alzheimer's disease, Parkinson's disease, atherosclerosis, chronic kidney disease (CKD), diabetes, gastroenteritis, rheumatoid arthritis, and the like.

Abstract: The present invention provides an embodiment of an electronic device, including: an ultrasonic transmitting transducer, arranged to transmit a first ultrasonic signal, at a first time point, to an object to be tested at a first time point, wherein the first ultrasonic signal is reflected by the object to be tested to serve as a second ultrasonic signal; first, second and third ultrasonic receiving transducers, arranged to receive the second ultrasonic signal; and a processor, arranged to use Short-Time Fourier Transform to calculate a second time point, a third time point, and a fourth time point at which the first, second and third ultrasonic receiving transducers receive the second ultrasonic signal, and arranged to calculate the relative positions of the object to be tested and the ultrasonic transmitting transducer according to the second time point, the third time point, and the fourth time point.

Abstract: The present invention relates generally to the use of a class of surfactants for emulsion and droplet polymerase chain reaction (“PCR”) mixtures. The class of surfactants consists of those having the chemical formula R—(OCH2CH2)n—OH, wherein R is an alkyl group consisting of 12 to 18 carbons and n is 2 to 25. The present invention also relates to methods, devices, systems, and kits incorporating the above-described class of surfactants.

Abstract: A system and method for detection, reduction of combustion resonance and engine control is provided. The system senses ion current within one or each cylinder of a multi-cylinder engine and determines combustion resonance from the ion current signal. In addition, the system may determine an engine control strategy to reduce combustion resonance based on the feedback from the ion current signal.