Patents Assigned to Viacyte, Inc.
  • Method of enriching for pancreatic endoderm cells
    Patent number: 9506034
    Abstract: The present disclosure relates to compositions and methods comprising cell surface markers for hES-derived cells, in particular, endoderm lineage cells including pancreatic endoderm-type cells, derived from hES cells.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: November 29, 2016
    Assignee: ViaCyte, Inc.
    Inventors: Olivia Kelly, Anne Bang
  • DEFINITIVE ENDODERM CELLS AND HUMAN PLURIPOTENT STEM CELLS
    Publication number: 20160340645
    Abstract: Disclosed herein are methods of identifying one or more differentiation factors that are useful for differentiating cells in a cell population comprising definitive endoderm cells into cells which are capable of forming tissues and/or organs that are derived from the gut tube.
    Type: Application
    Filed: May 2, 2016
    Publication date: November 24, 2016
    Applicant: ViaCyte, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Emmanuel E. Baetge
  • PDX1-expressing dorsal and ventral foregut endoderm
    Patent number: 9499795
    Abstract: Disclosed herein are cell cultures comprising dorsal and/or ventral PDX1-positive foregut endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified dorsal and/or ventral PDX1-positive foregut endoderm cells as well as methods for enriching, isolating and purifying dorsal and/or ventral PDX1-positive foregut endoderm cells from other cell types. Methods of identifying differentiation factors capable of promoting the differentiation of dorsal and/or ventral PDX1-positive foregut endoderm cells, are also disclosed.
    Type: Grant
    Filed: August 9, 2013
    Date of Patent: November 22, 2016
    Assignee: ViaCyte, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Emmanuel E. Baetge
  • Small molecules supporting pluripotent cell growth and methods thereof
    Patent number: 9458426
    Abstract: The present invention relates to compositions and methods for maintaining undifferentiated pluripotent stem cell cultures.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: October 4, 2016
    Assignee: VIACYTE, INC.
    Inventors: Thomas C Schulz, Allan J Robins
  • Loading system for an encapsulation device
    Patent number: 9433557
    Abstract: The present invention provides, in at least one embodiment, a loading device, system and method that loads aggregate cells into an encapsulation device for implanting into a patient. The loading system uses negative pressure from a low pressure pump in a closed system to improve safety and cell viability while allowing for even loading of the encapsulation device.
    Type: Grant
    Filed: February 21, 2011
    Date of Patent: September 6, 2016
    Assignee: VIACYTE, INC.
    Inventors: Chad Green, Laura Martinson, Val Anthony Bellora, Richard Alexander Grant, Evert Kroon, Emmanuel Edward Baetge
  • CRYOPRESERVATION, HIBERNATION AND ROOM TEMPERATURE STORAGE OF ENCAPULATED PANCREATIC ENDODERM CELL AGGREGATES
    Publication number: 20160250262
    Abstract: Disclosed herein are methods for cryopreserving, hibernation and room temperature storage of PEC aggregates, implantable semipermeable devices and the VC combination product.
    Type: Application
    Filed: September 4, 2015
    Publication date: September 1, 2016
    Applicant: ViaCyte, Inc.
    Inventors: Alan Agulnick, Laura Martinson, Evert Kroon, Michael Scott, Chad Green
  • Agents and methods for inhibiting human pluripotent stem cell growth
    Patent number: 9365830
    Abstract: The present invention relates to compositions and methods for inhibiting or suppressing undifferentiated or pluripotent stem cell growth and proliferation in a differentiated or differentiating cell population or culture.
    Type: Grant
    Filed: December 8, 2010
    Date of Patent: June 14, 2016
    Assignee: VIACYTE, INC.
    Inventors: Thomas Schulz, Allan Robins
  • Methods and compositions for feeder-free pluripotent stem cell media containing human serum
    Patent number: 9267110
    Abstract: The present invention provides compositions and methods for the culture and maintenance of pluripotent stem cells. More particularly, the present invention provides for compositions and methods for culturing, maintaining, growing and stabilizing primate pluripotent stem cells in a feeder-free defined media further comprising human serum, or a soluble attachment component of the human serum, for promoting cell attachment.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: February 23, 2016
    Assignee: VIACYTE, INC.
    Inventors: Allan J Robins, Thomas C Schulz
  • Methods for making anterior foregut endoderm
    Patent number: 9222069
    Abstract: Disclosed herein are cell cultures comprising PDX1-positive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified PDX1-positive endoderm cells as well as methods for enriching, isolating and purifying PDX1-positive endoderm cells from other cell types. Methods of identifying differentiation factors capable of promoting the differentiation of endoderm cells, such as PDX1-positive foregut endoderm cells and PDX1-negative definitive endoderm cells, are also disclosed.
    Type: Grant
    Filed: January 2, 2014
    Date of Patent: December 29, 2015
    Assignee: ViaCyte, Inc.
    Inventors: Kevin Allen D'Amour, Alan D. Agulnick, Susan Eliazer, Emmanuel E. Baetge
  • TOOLS AND INSTRUMENTS FOR USE WITH IMPLANTABLE ENCSAPSULATION DEVICES
    Publication number: 20150297294
    Abstract: Embodiments herein describe tools and instruments for holding, transferring, delivering, deploying an implantable device and methods and means of aseptically storing and shipping the implantable device including but not limited to a device case for protecting, housing and filling the device, a surgical sizer for preparing the implantable site, a deployer for transferring the implantable device from the device case and delivering or deploying the implantable device at the prepared implantable site.
    Type: Application
    Filed: April 16, 2014
    Publication date: October 22, 2015
    Applicant: ViaCyte, Inc.
    Inventors: Vincent So, Erik Olson, Michael Scott, Chad Green, Giacomo Strollo, Gustavo Prado, Craig McGreevy, Laura Martinson, Donald Koenig
  • Encapsulation of pancreatic cells derived from human pluripotent stem cells
    Patent number: 9132226
    Abstract: The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: September 15, 2015
    Assignee: ViaCyte, Inc.
    Inventors: Laura Martinson, Chad Green, Evert Kroon, Emmanuel Edward Baetge
  • Cell encapsulation device
    Patent number: D747467
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: January 12, 2016
    Assignee: VIACYTE, INC.
    Inventor: Chad Green
  • Cell encapsulation device
    Patent number: D747468
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: January 12, 2016
    Assignee: VIACYTE, INC.
    Inventor: Chad Green
  • Cell encapsulation device
    Patent number: D747798
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: January 19, 2016
    Assignee: VIACYTE, INC.
    Inventor: Chad Green
  • Cell encapsulation device
    Patent number: D750769
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: March 1, 2016
    Assignee: VIACYTE, INC.
    Inventor: Chad Green
  • Cell encapsulation device
    Patent number: D750770
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: March 1, 2016
    Assignee: VIACYTE, INC.
    Inventor: Chad Green
  • Cell encapsulation device
    Patent number: D755986
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: May 10, 2016
    Assignee: VIACYTE, INC.
    Inventors: Chad Green, Vincent So, Laura Martinson, Michael Scott
  • Case for an encapsulation device
    Patent number: D760399
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: June 28, 2016
    Assignee: VIACYTE, INC.
    Inventors: Vincent So, Erik Olson, Michael Scott, Chad Green, Giacomo Strollo, Gustavo Prado, Craig McGreevy
  • Sizing tool for an encapsulation device
    Patent number: D761423
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: July 12, 2016
    Assignee: VIACYTE, INC.
    Inventors: Vincent So, Michael Scott, Gustavo Prado
  • Deployment tool for an encapsulation device
    Patent number: D761424
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: July 12, 2016
    Assignee: VIACYTE, INC.
    Inventors: Vincent So, Michael Scott, Chad Green, Gustavo Prado, Laura Martinson