Patents Examined by Alexander S Noguerola
  • Patent number: 11169109
    Abstract: An electrochemical detection chip includes a first substrate and a second substrate opposite to each other, a plurality of driving electrodes, first detection electrodes and second detection electrodes. The plurality of driving electrodes are arranged on a side of the first substrate facing toward the second substrate and are arranged independently. The first detection electrodes and the second detection electrodes are arranged at a plurality of positions on a side of the second substrate facing toward the first substrate that are directly opposite at least a part of the plurality of driving electrodes, and are spaced apart from each other.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: November 9, 2021
    Assignees: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Fengchun Pang, Peizhi Cai, Yue Geng, Le Gu, Chuncheng Che
  • Patent number: 11169071
    Abstract: In a method for analyzing samples involving the use of a device for analyzing samples, the device for analyzing samples includes at least a movement part through which a sample moves, and a measurement unit that is formed in a middle of the movement part and that measures a value of an ion current when the sample passes through the movement part. The analysis method includes at least a measurement step for measuring the value of the ion current when the sample passes through the movement part, and a determination step for determining a change over time in a quantity of ions from the value of the ion current measured in the measurement step. The quantity of ions includes a quantity of ions that have leaked from the sample during movement of the sample through the movement part.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: November 9, 2021
    Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, OSAKA UNIVERSITY, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
    Inventors: Hirotoshi Yasaki, Takao Yasui, Noritada Kaji, Yoshinobu Baba, Tomoji Kawai, Satoyuki Kawano, Kentaro Doi, Takeshi Yanagida, Mao Fukuyama
  • Patent number: 11162916
    Abstract: Various embodiments for methods and systems that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic of the sample containing the analyte and deriving one of a batch slope, sampling time, or combinations thereof to attain accurate glucose concentration.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: November 2, 2021
    Assignee: Lifescan IP Holdings, LLC
    Inventors: Michael Malecha, Antony Smith, David McColl
  • Patent number: 11162060
    Abstract: A novel Self-Locking Optoelectronic Tweezers (SLOT) for single microparticle manipulation across a large area is provided. DEP forces generated from ring-shape lateral phototransistors are utilized for locking single microparticles or cells in the dark state. The locked microparticles or cells can be selectively released by optically deactivating these locking sites.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: November 2, 2021
    Assignee: The Regents of the University of California
    Inventors: Yajia Yang, Yufei Mao, Pei-Yu E. Chiou, Chi On Chui
  • Patent number: 11156580
    Abstract: The present disclosure relates to an electrode of an electrochemical measuring system and includes a housing having a chamber in which an electrolyte is arranged, and a potential-forming element which is at least partially arranged in the chamber such that the electrolyte at least partially wets the potential-forming element. A discharge line is made of coinage metal or of an alloy comprising a coinage metal and contacts the potential-forming element. A closure element closes the housing and guides discharge line therethrough. An adhesion promoter which comprises a glass and/or a glass-ceramic material and is arranged between the closure element and the discharge line.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: October 26, 2021
    Assignee: Endress+Hauser Conducta GmbH+Co. KG
    Inventors: Michael Hanko, Conny Fraas, Matthäus Speck
  • Patent number: 11156581
    Abstract: A biosensor that can perform analysis based on a sample noninvasively collected from a human body is provided. The biosensor comprises an identification substance (38) that binds to a substance to be detected (40), and an electrode (16) charged with a charge of the identification substance (38), comprises an inhibitor (39) that inhibits a substance not to be detected (42) from attaching to at least one of the identification substance (38) and the electrode (16), and detects a change in a charge density of the electrode (16) caused by binding of the substance to be detected (40) to the identification substance (38).
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: October 26, 2021
    Assignee: The University of Tokyo
    Inventors: Toshiya Sakata, Taira Kajisa, Yuya Miyazawa, Yuta Uematsu
  • Patent number: 11150217
    Abstract: A method of directly measuring SO2 and other trace gases by configuring an electrochemical cell (ECC) sonde; and an ECC sonde pump inlet filter to remove ozone and other trace gases. Further, calibration and operation procedures for the SO2 and other trace gas ECC sondes are disclosed.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: October 19, 2021
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventors: James Flynn, Gary A. Morris
  • Patent number: 11143645
    Abstract: A test strip for electrochemical testing of a blood analyte includes a plurality of test sites for the electrochemical testing of analytes on a single test strip. Each test site includes a first receiving port, the first receiving port for receiving a blood sample, the first receiving port at a first end of the test strip. The test site further includes a first electrode and a second electrode, the first and second electrodes proximate to the first receiving port. Each test site further includes a first contact and a second contact, the first and second contacts at a second end of the test strip, the first and second contacts interconnected with the first and second electrodes, respectively.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: October 12, 2021
    Assignee: POLYMER TECHNOLOGY SYSTEMS, INC.
    Inventors: Gary L. Hughes, Aniruddha Patwardhan
  • Patent number: 11143617
    Abstract: In various embodiments a molecular circuit is disclosed. The circuit comprises a negative electrode, a positive electrode spaced apart from the negative electrode, and a binding probe molecule conductively attached to both the positive and negative electrodes to form a circuit having a conduction pathway through the binding probe. In various examples, the binding probe is an antibody, the Fab domain of an antibody, a protein, a nucleic acid oligomer hybridization probe, or an aptamer. The circuit may further comprise molecular arms used to wire the binding probe to the electrodes. In various embodiments, the circuit functions as a sensor wherein electrical signals, such as changes to voltage, current, impedance, conductance, or resistance in the circuit, are measured as targets interact with the binding probe. In various embodiments, the circuit provides a means to measure the presence, absence, or concentration of an analyte in a solution.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: October 12, 2021
    Assignee: ROSWELL BIOTECHNOLOGIES, INC.
    Inventors: Barry L. Merriman, Venkatesh Alagarswamy Govindaraj, Paul Mola, Tim Geiser, Gina Costa
  • Patent number: 11136612
    Abstract: A reagent used for a glucose sensor for electrochemical, quantitative determination of glucose, includes a flavin adenine dinucleotide glucose dehydrogenase, single-walled carbon nanotubes, and a dispersant.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: October 5, 2021
    Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Hitoshi Muguruma, Atsunori Hiratsuka, Hisanori Iwasa, Jun Takagi, Hiroyasu Kadoya
  • Patent number: 11131644
    Abstract: A biosensor and a biological detection method are provided. The biosensor includes a substrate, a plurality of first and second electrodes in a strip shape, a material layer and a capture antibody. The substrate has a sampling region and a measuring region connected to the sampling region. The first and second electrodes are disposed on the substrate in the measuring region, and the first and second electrodes are arranged alternately with each other, wherein the first electrodes are connected in parallel with each other, and the second electrodes are connected in parallel with each other.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: September 28, 2021
    Assignee: Industrial Technology Research Institute
    Inventors: Hui-Chu Hsieh, Wen-Pin Hsieh, Nien-Jen Chou, Hui-Ju Shen, Hui-Ling Peng, Jing-Tsyr Lin
  • Patent number: 11131648
    Abstract: According to one aspect of the invention, a potentiometric sensor having a cathode and an anode. The cathode is configured to provide a summary voltage representative of at least two voltage points. The anode is configured to provide a first voltage. The cathode is in communication with the anode by a first electrolyte forming an open circuit having an open circuit potential. Within the first electrolyte is a concentration of a target ion. The open circuit potential mathematically corresponds to the concentration of the target ion.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: September 28, 2021
    Assignee: U.S. Department of Energy
    Inventors: Guoping Cao, Shelly X. Li, Steven Herrmann, Brenda Serrano-Rodriguez
  • Patent number: 11124890
    Abstract: Provided herein is a method for measuring a concentration of a metal ion in an electrodeposition solution. The method of the present disclosure can substantially reduce the interference of organic additives and different electrode conditions on voltammetric metal ion concentration measurements.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: September 21, 2021
    Assignee: Hong Kong Applied Science and Technology Research Institute Company Limited
    Inventors: Yaofeng Sun, Shaoqin Xie, Liya Zheng
  • Patent number: 11125715
    Abstract: A sensor element of a gas sensor includes a solid electrolyte body which has oxygen-ion conductivity, a measuring electrode that is exposed to a measured gas, a reference gas electrode that is exposed to a reference gas, and a porous protection layer. The measuring electrode is mounted on an outer surface of the solid electrolyte body. The reference electrode is mounted on an inner surface of the solid electrolyte body. The protection layer covers a surface of the measuring electrode. A plurality of open portions are formed to penetrate through the measuring electrode. A part of the protection layer is joined to the solid electrolyte body, via the plurality of open portions.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: September 21, 2021
    Assignee: DENSO CORPORATION
    Inventors: Akira Saito, Kiyomi Kobayashi
  • Patent number: 11125711
    Abstract: The present disclosure relates to a reference electrode including an electrical conductor, an electrically conductive salt bridge provided for contact with a measuring fluid, and a medium electrically conductively connecting the electrical conductor and the salt bridge to each other, wherein the medium and the electrical conductor are completely isolated with respect to the measuring fluid. The salt bridge comprises a polymer matrix and a conducting salt, the conducting salt is formed from a cation and an anion, and the cation and/or the anion are at least partially kept from leaching in the polymer matrix. The present disclosure further relates to an electrochemical sensor, a method for producing the reference electrode and a method for regenerating and/or conditioning the reference electrode.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: September 21, 2021
    Assignee: Endress+Hauser Conducta GbmH+Co. KG
    Inventor: Matthaeus Speck
  • Patent number: 11125718
    Abstract: A method for operating a nitrogen oxide sensor comprising: sensing a first measurement signal of the nitrogen oxide sensor, the first measurement signal representing a detected voltage between a reference electrode and an external electrode; sensing a second measurement signal representing a measured gas content in a measuring chamber of the nitrogen oxide sensor; comparing the first measurement signal with a predefined first threshold value; and if the first threshold value is exceeded, assigning the second measurement signal to an emission of NH3.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: September 21, 2021
    Assignee: VITESCO TECHNOLOGIES GMBH
    Inventor: Hong Zhang
  • Patent number: 11119068
    Abstract: The present invention provides, in some embodiments, an isotachophoresis (ITP) apparatus, a kit comprising same and method of use thereof for the focusing analytes of interest from large sample volumes.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: September 14, 2021
    Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Moran Bercovici, Govind Kaigala, Xander Frank Van Kooten, Nadya Ostromohov, Federico Paratore
  • Patent number: 11119067
    Abstract: The present disclosure relates to a glass electrode including an analyte-sensitive glass membrane, an electrically conductive lead, and an intermediate layer which conductively connects the lead and the glass membrane to one another. According to the present disclosure, the intermediate layer is made of an electron- and/or ion-conducting polymer.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: September 14, 2021
    Assignee: Endress+Hauser Conducta GmbH+Co. KG
    Inventors: Matthaeus Speck, Thomas Wilhelm
  • Patent number: 11098339
    Abstract: A method for testing enzyme based electrochemical sensors wherein an electrochemical sensor is provided. A measurement setup is provided, which is operatively coupled to the electrochemical sensor, providing an output signal Z, e.g. a measured signal current, of the electrochemical sensor; and the electrochemical sensor is suitably contacted with a test solution comprising a certain concentration of the primary analyte. The electrochemical sensor is subjected to a certain swept range of temperatures T; an output signal Z is measured for different temperature values T; a derivative Z? of the output signal Z as a function of temperature T, or inverse temperature 1/T, is determined; and a relative derivate Z?/Z at a temperature T, or inverse temperature 1/T, is determined as the ratio between derivative Z? and output signal Z.
    Type: Grant
    Filed: July 4, 2017
    Date of Patent: August 24, 2021
    Assignee: ROCHE DIABETES CARE, INC.
    Inventor: Herbert Wieder
  • Patent number: 11073494
    Abstract: A trace metal analysis detector and method of operating the same to detect metals in various fluid samples using boron doped diamond working electrodes.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: July 27, 2021
    Assignee: Fraunhofer USA, Inc.
    Inventors: Michael Frank Becker, Thomas Schuelke