Patents Examined by M. C.
  • Oxidation of thiols employing cobalt molybdate/triethylamine catalyst
    Patent number: 4288627
    Abstract: A thiol is oxidized to a corresponding disulfide employing a supported cobalt molybdate catalyst in combination with a liquid tertiary amine. 2-propanethiol is converted to diisopropyl disulfide with conversions of the order of 94% and selectivities of the order of 98%.
    Type: Grant
    Filed: February 12, 1980
    Date of Patent: September 8, 1981
    Assignee: Phillips Petroleum Company
    Inventor: Donald H. Kubicek
  • Process for preparing bisphenol sulfone derivatives
    Patent number: 4287366
    Abstract: A process for preparing bisphenol sulfone derivatives represented by the general formula (I) ##STR1## where R stands for hydrogen, a halogen, an alkyl radical, a cycloalkyl radical, an aryl radical, an aralkyl radical, hydroxyl group, an alkoxy radical, allyloxy group, carboxyl group, or a carboalkoxy radical, m is an integer of from 1 to 3, and when m is 2 or more, R may be identical to or different from each other, and adjacent Rs may be combined to form a ring, by oxidizing with hydrogen peroxide a compound represented by the general formula (II) ##STR2## where R and m have the same meanings as defined for the formula (I), and n is zero or 1, in the presence of an alkali in an amount more than the equimolar amount thereof relative to said compound in water and/or an organic solvent which do not form any organic peracids under reaction conditions.
    Type: Grant
    Filed: March 10, 1980
    Date of Patent: September 1, 1981
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Akihiro Yamaguchi, Keizaburo Yamaguchi, Hisamichi Murakami, Tadashi Kobayashi
  • Trihalocyclopropyl carbonates
    Patent number: 4285882
    Abstract: When the reaction of aldehydes with alkali metal trihaloacetates is carried out in the presence of a highly polar aprotic solvent (DMF, DMSO), novel organic alkali metal carbonates, which are precursors of pyrethroid insecticides, are formed in high yields and at a high rate. Novel sulfonates and dihalophosphites, derived from these carbonates have also been claimed.
    Type: Grant
    Filed: March 25, 1980
    Date of Patent: August 25, 1981
    Assignee: Shell Oil Company
    Inventors: Petrus A. Kramer, Pieter A. Verbrugge
  • 2-Chloro-4,5-disubstituted-thiazoles useful as herbicidal safeners
    Patent number: 4284426
    Abstract: 2-chloro-4,5-disubstituted-thiazoles have been found to be effective in reducing herbicidal injury to sorghum plants due to the application thereto of acetanilide and thiocarbamate herbicides.
    Type: Grant
    Filed: October 1, 1979
    Date of Patent: August 18, 1981
    Assignee: Monsanto Company
    Inventors: Robert K. Howe, Len F. Lee
  • Mixed disulfides
    Patent number: 4284624
    Abstract: This invention is directed to compounds of the formula ##STR1## wherein A and A.sub.1 are amino acid residues, X is and .alpha.-imino acid residue, and R.sub.1 is hydrogen, lower alkyl, or halo substituted lower alkyl. These compounds are useful as hypotensive agents.
    Type: Grant
    Filed: May 2, 1980
    Date of Patent: August 18, 1981
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Sesha I. Natarajan, Miguel A. Ondetti, Shih-jung Lan, Keith K. Wong
  • Hydroxamic acid derivatives of mercaptoacyl amino acids
    Patent number: 4284561
    Abstract: Hydroxamic acid derivatives of certain mercaptoacyl amino acids inhibit the conversion of angiotensin I to angiotensin II in mammals and are useful for the treatment of hypertension.
    Type: Grant
    Filed: December 3, 1979
    Date of Patent: August 18, 1981
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Edward W. Petrillo, Jr., Miguel A. Ondetti
  • Process for preparing thiophenols
    Patent number: 4284817
    Abstract: Thiophenols are produced by reacting the corresponding benzene compound with hydrogen sulfide in contact with an absorptive catalyst, such as activated carbon, calcined petroleum coke, etc. Temperatures in the range of from about 500.degree. to 900.degree. C. are employed.
    Type: Grant
    Filed: June 2, 1977
    Date of Patent: August 18, 1981
    Assignee: Stauffer Chemical Company
    Inventors: Kyung S. Shim, Adam E. Skrzec
  • Emulsifiable concentrate for weed control
    Patent number: 4283222
    Abstract: An emulsifiable concentrate for weed control, which comprises 10 to 20 parts by weight of N'-[4-(4-methylphenethyloxy)phenyl]-N-methoxy-N-methylurea, 5 to 15 parts by weight of an emulsifier, 10 to 70 parts by weight of at least one of aromatic hydrocarbon solvents of the formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are each hydrogen or alkyl having 1 to 3 carbon atoms and 15 to 75 parts by weight of at least one of ketonic solvents having not more than 9 carbon atoms, of which the water solubility is not more than 10% by weight at room temperature.
    Type: Grant
    Filed: May 20, 1980
    Date of Patent: August 11, 1981
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Fumio Horide, Kozo Tsuji
  • Process for producing dialkyl dithiophosphoric acid esters
    Patent number: 4283335
    Abstract: Disclosed is a method for improving the yield of dialkyl dithiophosphoric acid esters produced by the Lewis acid catalyzed reaction of an O,O-dialkyl dithiophosphoric acid and an organic chloride. More specifically, the method concerns the improvement wherein the reaction is carried out in the presence of from 0.1 to 1.5 moles, per mole of organic chloride, of an anhydride of a fatty acid containing 2 to 5 carbon atoms.
    Type: Grant
    Filed: February 22, 1980
    Date of Patent: August 11, 1981
    Assignee: Boots Hercules Agrochemicals Co.
    Inventor: James Minn
  • Process for producing O,O-dialkyl dithiophosphoric acid esters
    Patent number: 4283338
    Abstract: Disclosed is a method for improving the yield of dialkyl dithiophosphoric acid esters produced by the Lewis acid catalyzed reaction of an O,O-dialkyl dithiophosphoric acid and an organic chloride. More specifically, the method concerns the improvement wherein the reaction is conducted under sufficient pressure to maintain the liberated hydrogen chloride in the reaction system during the course of the reaction.
    Type: Grant
    Filed: February 22, 1980
    Date of Patent: August 11, 1981
    Assignee: Boots Hercules Agrochemicals Co.
    Inventor: James Minn
  • Herbicidal and plant-growth-regulating N-substituted-N-(2,5-dialkylpyrrol-1-yl) haloacetamides
    Patent number: 4282028
    Abstract: Compounds of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are alkyl or halo; R.sup.3 is hydrogen or alkyl; Z is halo; and R.sup.4 is alkoxycarbonyl, alkoxy, phenyl, substituted phenyl,a group of the formula ##STR2## wherein R.sup.5 and R.sup.6 are hydrogen, alkyl, alkenyl or alkynyl; a group of the formula ##STR3## wherein R.sup.7 and R.sup.8 are hydrogen and alkyl; a five or six-membered aromatic heterocyclic ring of the formula ##STR4## wherein at least one of V, W, X or Y is an oxygen, sulfur or nitrogen atom, R.sup.9 is alkyl and n is 0, 1, 2 or 3 have herbicidal and plant-growth-regulating activity.
    Type: Grant
    Filed: July 25, 1979
    Date of Patent: August 4, 1981
    Assignee: Chevron Research Company
    Inventor: Stephen D. Ziman
  • Reactive asymmetrical dicarboxylic acid esters and reagents for the investigation of cardiac glycosides
    Patent number: 4282151
    Abstract: New reactive asymmetrical dicarboxylic acid ester compounds of the formula ##STR1## wherein R.sub.1 is an alkyl radical containing up to 3 carbon atoms or is a digoxin or digitoxin residue, R.sub.2 and R.sub.3, which may be the same or different, are alkoxy radicals containing up to 3 carbon atoms or together represent an oxygen atom, X is a cyanomethoxy, succinimide-N-oxy, N-methyl-pyridiniumoxy, 2,4-dinitrophenoxy, 2,4,5-trichlorophenoxy, pentachlorophenoxy, phenylthio, p-nitrophenoxy, n-nitrophenylthio, piperidyl-N-oxy, phthalimido-N-oxy or benztriazol-N-oxy radical and n is 2, 3, 4 or 5, are useful for the preparation of reagents for the investigation of cardiac glycosides (Digitalis glycosides).
    Type: Grant
    Filed: March 6, 1978
    Date of Patent: August 4, 1981
    Assignee: Boehringer Mannheim GmbH
    Inventors: Hans-Georg Batz, Hans-Ralf Linke, Klaus Stellner, Gunter Wiemann
  • Sulfonyl ureas and pharmaceutical preparations thereof
    Patent number: 4282239
    Abstract: Sulfonylureas of the formula ##STR1## in which n, R, R.sup.1, X and Y have the indicated meanings and the physiologically acceptable salts thereof, pharmaceutical preparations on the basis of said compounds and their use in the treatment of diabetes.
    Type: Grant
    Filed: June 25, 1979
    Date of Patent: August 4, 1981
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rudi Weyer, Volker Hitzel, Karl Geisen, Gunter Regitz
  • Crosslinkable bis-imidyl derivatives
    Patent number: 4280946
    Abstract: New crosslinkable bis-imidyl derivatives are described which can be produced by reaction of imidylphthalic acid derivatives, such as maleimidyl-phthalic acid anhydrides, with monomeric, oligomeric or polymeric diamines. The new crosslinkable bis-imidyl derivatives can be used for producing crosslinked polymers which are distinguished, in particular, by their stability to oxidation and to heat.
    Type: Grant
    Filed: December 3, 1979
    Date of Patent: July 28, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Roland Darms, Vratislav Kvita, Gerd Greber
  • Process for producing indoline derivative
    Patent number: 4280958
    Abstract: An indoline derivative having the formula ##STR1## is produced by a cyclization of 2-halogenophenethylamine having the formula ##STR2## wherein R.sub.1 represents a hydrogen atom or a lower alkyl, a lower alkoxyl, nitro or hydroxyl group; R.sub.2 represents a hydrogen atom or a lower alkoxyl or nitro group; and R.sub.3 represents a hydrogen atom, a lower alkyl, a substituted lower alkyl or a substituted amino group; and X represents a halogen atom in the presence of a copper type catalyst and an amine which is selected from the group consisting of (1) compounds having the formulaR.sub.3-n NH.sub.nwherein R represents a C.sub.1-16 alkyl group or C.sub.1-8 alkoxy group; n is 0 to 2 and R can be the same or different in the case of n is 1 or 0; (2) compounds having the formulaH.sub.2 N(CH.sub.2).sub.n NH andH.sub.2 N(CH.sub.2).sub.n NH(CH.sub.2).sub.n NH.sub.
    Type: Grant
    Filed: October 3, 1979
    Date of Patent: July 28, 1981
    Assignee: Ihara Chemical Industry Co., Ltd.
    Inventors: Yoshiki Nakayama, Yasushi Higuchi, Chihiro Yazawa
  • 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
    Patent number: 4281131
    Abstract: Disclosed are compounds which are 4-hydroxy-2-quinolinone-3-carboxylic acids and salts thereof, e.g., 1-allyl-6,7-dimethoxy-4-hydroxy-2-quinolinone-3-carboxylic acid, useful as anti-allergic agents, and prepared by hydrolysis of the corresponding carboxylic acid esters.
    Type: Grant
    Filed: July 16, 1979
    Date of Patent: July 28, 1981
    Assignee: Sandoz, Inc.
    Inventor: Goetz E. Hardtmann
  • Preparation of mercapto-alcohols
    Patent number: 4281202
    Abstract: A process for preparing mercapto-alcohols by reacting a molar excess of hydrogen sulfide with an alkylene, cycloalkylene, or aralkylene oxide in the presence of an alkali metal zeolite catalyst.
    Type: Grant
    Filed: April 29, 1980
    Date of Patent: July 28, 1981
    Assignee: Pennwalt Corporation
    Inventors: Bernard Buchholz, Charles B. Welsh, Henry C. Miller
  • Process for preparing 3-azabicyclo(3.1.0)hexane-2-carboxylic acid
    Patent number: 4279821
    Abstract: 3-Azabicyclo(3.1.0)hexane-2-carboxylic acid, a plant gametocide, is prepared by effecting reaction between cis 2-aminomethylcyclopropyl-1,1-dimethyl acetal and a cyanide in the presence of a liquid lower-alkanecarboxylic acid; treating the resulting N-alkanoyl-3-azabicyclo(2.1.0)hexane-2-carbonitrile with a strong acid; treating the resulting 3-alkanoyl-3-azabicyclo(3.1.0)hexane-2-carboxylic acid with strong acid to form the desired 3-azabicyclo(3.1.0)hexane-2-carboxylic acid.
    Type: Grant
    Filed: July 7, 1980
    Date of Patent: July 21, 1981
    Assignee: Shell Oil Company
    Inventors: Janet A. Day, Barry R. J. Devlin, Robert J. G. Searle
  • Dichloroacetylimino herbicide antagonists as plant protection agents
    Patent number: 4279636
    Abstract: New compounds which are herbicide antagonists that are useful for protection of plants from various herbicides are members of the group having the general structural formulas: ##STR1## in which R is hydrogen or C.sub.1 to C.sub.4 alkyl, alkenyl or alkynyl, branched or straight chain, R.sup.1 is C.sub.1 to C.sub.3 alkyl, alkenyl or alkynyl, branched or straight chain, with the total number of carbon atoms in R and R.sup.1 being less than six, preferably less than four, on compounds with both R and R.sup.1 substituents. The novel plant protection agents may be applied both to seeds and to the soil.
    Type: Grant
    Filed: April 4, 1980
    Date of Patent: July 21, 1981
    Assignee: Gulf Oil Corporation
    Inventors: Otto L. Hoffmann, Joel L. Kirkpatrick
  • Process for preparing phenols and thiophenols
    Patent number: 4278816
    Abstract: Phenols and thiophenols are produced by reacting the corresponding diphenyl ether compound with hydrogen sulfide in contact with an absorptive catalyst, such as charcoal, activated carbon, calcined petroleum coke, etc. Temperatures in the range of from about 300.degree. to about 900.degree. C. are employed.
    Type: Grant
    Filed: August 26, 1977
    Date of Patent: July 14, 1981
    Assignee: Stauffer Chemical Company
    Inventor: Kyung-sup Shim