Patents Examined by Robert J Yamasaki
  • Patent number: 11597853
    Abstract: Bioactive coatings that are stabilized against inactivation by weathering are provided including a base associated with a chemically modified enzyme, and, optionally a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate to form an active coating facilitating the removal of organic stains or organic material from food, insects, or the environment.
    Type: Grant
    Filed: January 26, 2019
    Date of Patent: March 7, 2023
    Assignees: Toyota Motor Corporation, Regents of the University of Minnesota
    Inventors: Hongfei Jia, Ping Wang, Liting Zhang, Andreas Buthe, Xueyan Zhao, Songtao Wu, Masahiko Ishii, Minjuan Zhang
  • Patent number: 11589588
    Abstract: The invention relates, in part, to methods to identify compounds to treat a phytoparasitic nematode infection and/or reduce phytoparasitic nematode contamination, and to methods and compositions to treat phytoparasitic nematode infections and to reduce phytoparasitic nematode contamination of a substrate such as, but not limited to: a plant, agricultural medium, or soil.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: February 28, 2023
    Assignee: University of New Hampshire
    Inventors: Richard H. Cote, Karyn B. Cahill, Kevin D. Schuster
  • Patent number: 11591635
    Abstract: A method for screening substances for their ability to reduce malodours from emanations from an animal, said method comprising determining the effect of said substances on the C-S lyase activity of bacteria that emit volatile sulphuric compounds (VSCs), by contacting a test substance with a sample comprising said bacteria or a supernatant obtainable from a culture of said bacteria in the presence of a substrate for a C-S lyase, detecting the levels of thiol production from said bacteria, and comparing the results with those obtained from similar bacteria in the absence of said substance.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: February 28, 2023
    Assignee: Mars, Incorporated
    Inventors: Taichi Inui, Richard Mark Haydock
  • Patent number: 11578350
    Abstract: In order to quantitatively characterize biological objects, for example individual cells, a stimulus is applied to a biological object (8) in a contactless fashion. A measurement and a further measurement are performed on the biological object (8) in order to ascertain a response of the biological object (8) to the stimulus, wherein the measurement and the further measurement comprise detecting Raman scattering on and/or in the biological object (8) and/or capturing data using digital holographic microinterferometry (DHMI). The biological object (8) is characterized according to a result of the measurement and is sorted if needed. The stimulus can be applied by means of a laser beam that creates optical tweezers or an optical trap, by means of ultrasonic waves or an electric or magnetic radio frequency field.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: February 14, 2023
    Inventors: Raimund Schütze, Karin Schütze
  • Patent number: 11572577
    Abstract: The invention discloses a fermentation method for production of fucoxanthin by Nitzschia laevis, including the following steps of: step A, preparation of inocula; step B, fermentation culture: inoculating of Nitzschia laevis according to a certain volume ratio to reaction kettle containing sterile fermentation medium for aeration fermentation, preparing fucoxanthin fermentation broth through culture mean of fed-batch nutrient components; step C, obtaining high fucoxanthin induction culture solution by aeration induction culture under irradiation of monochromatic light or mixed light; extracting fucoxanthin from high fucoxanthin induction culture solution.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: February 7, 2023
    Assignee: PEKING UNIVERSITY
    Inventors: Feng Chen, Bin Liu
  • Patent number: 11570959
    Abstract: System and methods for monitoring the growth of an aquatic plant culture and detecting real-time characteristics associated with the aquatic plant culture aquatic plants. The systems and methods may include a control unit configured to perform an analysis of at least one image of an aquatic plant culture. The analysis may include processing at least one collected image to determine at least one physical characteristic or state of an aquatic plant culture. Systems and methods for distributing aquatic plant cultures are also provided. The distribution systems and methods may track and control the distribution of an aquatic plant culture based on information received from various sources. Systems and methods for growing and harvesting aquatic plants in a controlled and compact environment are also provided. The systems may include a bioreactor having a plurality of vertically stacked modules designed to contain the aquatic plants and a liquid growth medium.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: February 7, 2023
    Assignee: GreenOnyx LTD
    Inventors: Tsipi Shoham, Benjamin Shoham
  • Patent number: 11566149
    Abstract: Bioactive coatings that are stabilized against inactivation by weathering are provided including a base associated with a chemically modified enzyme, and, optionally a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate to form an active coating facilitating the removal of organic stains or organic material from food, insects, or the environment.
    Type: Grant
    Filed: January 26, 2019
    Date of Patent: January 31, 2023
    Assignees: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Hongfei Jia, Ping Wang, Liting Zhang, Andreas Buthe, Xueyan Zhao, Songtao Wu, Masahiko Ishii, Minjuan Zhang
  • Patent number: 11559801
    Abstract: Embodiments disclose an apparatus and methods for biological sample processing enabling isolation and enrichment of microbial or pathogenic constituents from the sample. A vessel for sample containment and extraction is further disclosed for engagement with a transducer capable of efficient sample disruption and lysis. Together these components provide a convenient and inexpensive solution for rapid sample preparation compatible with downstream analysis techniques.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: January 24, 2023
    Assignee: TANGEN BIOSCIENCES, INC.
    Inventors: John Richard Nobile, John F. Davidson
  • Patent number: 11549098
    Abstract: A process for separating sperm cells from a chemical compound by electrophoresis comprising subjecting the sperm cells to an electric potential between a cathode and an anode such that the sperm cells are separated from the chemical compound, and related methods including methods of using said sperm cells in intrauterine insemination.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 10, 2023
    Assignee: FERTILITY INNOVATIONS LIMITED
    Inventor: Michael Howard James
  • Patent number: 11542534
    Abstract: The present invention includes methods for preparing anticoagulant polysaccharides using several non-naturally occurring, engineered sulfotransferase enzymes that are designed to react with aryl sulfate compounds instead of the natural substrate, PAPS, to facilitate sulfo group transfer to polysaccharide sulfo group acceptors. Suitable aryl sulfate compounds include, but are not limited to, p-nitrophenyl sulfate or 4-nitrocatechol sulfate. Anticoagulant polysaccharides produced by methods of the present invention comprise N-, 3-O-, 6-O-sulfated glucosamine residues and 2-O sulfated hexuronic acid residues, have comparable anticoagulant activity compared to commercially-available anticoagulant polysaccharides, and can be utilized to form truncated anticoagulant polysaccharides having a reduced molecular weight.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: January 3, 2023
    Assignee: OPTIMVIA, LLC
    Inventors: Tarsis Ferreira Gesteira, Daniel H. Lajiness
  • Patent number: 11542410
    Abstract: Bioactive coatings that are stabilized against inactivation by weathering are provided including a base including an enzyme associated therein, and a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate to form an active coating facilitating the removal of organic stains or organic material from food, insects, or the environment.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: January 3, 2023
    Assignees: Toyota Motor Corporation, Regents of the University of Minnesota
    Inventors: Hongfei Jia, Ping Wang, Liting Zhang, Andreas Buthe, Xueyan Zhao, Songtao Wu, Masahiko Ishii, Minjuan Zhang
  • Patent number: 11535601
    Abstract: The invention relates to the field of pharmaceutical synthesis, in particular to a preparation method of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol derivatives and their intermediates. The preparation method is carried out starting from compound Formula A1. In the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol derivatives, the chirality was constructed by enzymatic method, and the products were prepared with high optical purity. The preparation method can be used to produce the key intermediates of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol of darunavir commercially, which is a very economical route suitable for industrial production.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: December 27, 2022
    Inventors: Zhaobo Gao, Jianhua Chen, Zhidong Wan, Dawei He, Zengle Zhou, Xiaodong Ma, Wei Xiang, Jingxin Lin, Yijiang Mei
  • Patent number: 11535773
    Abstract: Bioactive coatings suitable for facilitating removal of a fingerprint when contacting the coating are provided including a base associated with a chemically modified enzyme, and, optionally a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate. Also provided are processes of facilitating fingerprint removal.
    Type: Grant
    Filed: January 26, 2019
    Date of Patent: December 27, 2022
    Assignees: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Hongfei Jia, Ping Wang, Liting Zhang, Andreas Buthe, Xueyan Zhao, Songtao Wu, Masahiko Ishii, Minjuan Zhang
  • Patent number: 11519918
    Abstract: The present invention relates to a method for quantification of amino acids using a cell-free protein synthesis system.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: December 6, 2022
    Assignee: THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)
    Inventors: Dong-Myung Kim, Tae Hyeon Yoo, Kyung-Ho Lee, Yeon-Jae Jang
  • Patent number: 11492590
    Abstract: Non-genetically engineered mammalian cells modified by sortase-mediated conjugation of an agent thereto are provided. Methods of conjugating agents to non-genetically engineered mammalian cells using sortase are provided. Methods of using the cells, e.g., for diagnostic and/or therapeutic purposes, are provided.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: November 8, 2022
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Lee Kim Swee, Hidde L. Ploegh
  • Patent number: 11492653
    Abstract: Methods and compositions for detecting an antibiotic-inactivating factor produced by a microorganism are described herein.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: November 8, 2022
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Gina K. Thomson, Kenneth S. Thomson, Sameh Mohamed Mohamadi AbdelGhani
  • Patent number: 11485993
    Abstract: Disclosed herein are methods and compositions for antimicrobial quantification and functional measurement. In one aspect, a method for quantifying antimicrobial comprises: obtaining a biological sample from a patient receiving an antimicrobial; incubating the biological sample with a reference microbial strain and a fluorophore for detecting cell lesion; measuring a first signal of fluorescent intensity in the incubated biological sample using flow cytometry; and comparing the first signal to a calibrating curve previously generated for the antimicrobial, thereby quantifying the antimicrobial present in the biological sample.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: November 1, 2022
    Assignee: Fastinov S.A.
    Inventors: Cidalia Irene Azevedo Pina Vaz, Acacio Agostinho Goncalves Rodrigues
  • Patent number: 11484045
    Abstract: The invention relates to production of a yeast strain with increased mannan oligosaccharides, amino acids, and complex carbohydrates. The invention further relates to the process to propagate and ferment such yeast. The invention further relates to methods of use of the yeast as a feed additive for animals and a food product for humans.
    Type: Grant
    Filed: September 10, 2021
    Date of Patent: November 1, 2022
    Assignee: AGVAULT PROPERTIES, LLC
    Inventor: James Russell Zeeck
  • Patent number: 11484025
    Abstract: The present invention relates to a cryoprotecting agent comprising a cryprotectant being one or more of: dextrin, dextran, isomaltooligosaccharide and derivatives thereof, cryoprotecting and cryopreserved compositions, uses thereof, and methods of cryopreservation.
    Type: Grant
    Filed: November 29, 2013
    Date of Patent: November 1, 2022
    Assignee: PHARMACOSMOS HOLDING A/S
    Inventors: Hans Berg Andreasen, Lars Christensen, Kim Nordfjeld, Jeppe Skytte, Christian Clausen, Bjorn Holst
  • Patent number: 11486885
    Abstract: Disclosed is a reagent for determination of activated partial thromboplastin time, comprising: a phosphatidylcholine (PC); a phosphatidylserine (PS); and a phosphatidylethanolamine (PE), wherein a concentration ratio of the PS relative to the PC is not less than 0.16 and not more than 0.25, and a concentration of the PS is not less than 7 ?g/mL and not more than 13 ?g/mL.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: November 1, 2022
    Assignee: SYSMEX CORPORATION
    Inventors: Kohei Akatsuchi, Takahiko Bandou, Naoki Yamamoto, Masako Aki