Abstract: Systems and methods for removal of clot material from vessel lumens are disclosed. A medical device assembly can include a catheter having a lumen and a distal portion configured to be positioned at or adjacent a treatment site within a vessel. An expandable member has a first portion coupled to the distal portion of the catheter, and a second portion extending away from the catheter distal portion. An elongate shaft extends through the lumen of the catheter, and the second portion of the expandable member is releasably coupled to the shaft. When the shaft is slidably moved relative to the surrounding catheter, the second portion of the expandable member can be released from the shaft, and the shaft can be withdrawn or removed.

Abstract: The invention relates to a method for moving a bipedal exoskeleton (1) accommodating a human operator, the method being characterised in that it involves the implementation, by data processing means (11) of the exoskeleton (1), of the following steps: (a) obtaining at least one postural instruction to be applied by the exoskeleton (1) in order for the operator to perform an exercise movement; (b) determining a trajectory of the exoskeleton (1) by means of hierarchised inverse kinematics based on the at least one determined postural instruction, said hierarchised inverse kinematics comprising a stack of hierarchised tasks comprising, as the task of highest priority, a task of keeping the feet of the exoskeleton (1) on the ground as the operator performs the exercise movement.

Abstract: A display element having a substrate having a plurality of optical elements. The optical elements of a first grid consist of a first type of optical elements and the optical elements of a second grid consist of a second type of optical elements. The first type of optical elements is different from the second type of optical elements. In the event of tilting of the display element, the light spots 5 of the concave and convex mirror surfaces in this case move synchronously in opposing directions in the direction of the arrows, such that an observer 4 observes a particularly pronounced dynamic floating effect.

Abstract: A prosthetic heart valve for implant in a human. The valve includes a wireform with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area. Each leaflet may drape over the top of the wireform in the cusp area, but have tabs that each extend underneath the wireform at the commissure posts to be secured along with a tab of an adjacent leaflet. The prosthetic heart valve may also be a dual-wire wireform, with the leaflets sandwiched therebetween. One wireform may be larger than the other, with the leaflets extending over the smaller wireform. The smaller wireform may have commissures that bend radially outward from the larger wireform to provide structure to which the leaflet tabs attach.

Abstract: Retrieval of material from vessel lumens can be improved by electrically enhancing attachment of the material to the removal device. The removal device can have a core assembly that includes a hypotube coupled to a first electrical terminal and a pushwire coupled to a second electrical terminal, the pushwire extending through the hypotube lumen. An insulating layer separates the hypotube and the pushwire, and an interventional element is coupled to a distal end of the pushwire. The interventional element can be disposed adjacent to a thrombus. An electrical signal is delivered to the interventional element to promote adhesion of the thrombus to the interventional element. The electrical signal can optionally be a periodic waveform, and the total energy delivered can be between 0.75-24,000 mJ and the peak current delivered via the electrical signal can be between 0.5-5 mA.

Abstract: Techniques are described for transferring nanofiber forests using transfer films that either lack a conventional adhesive at the substrate—nanofiber forest interface or that include a diffusion barrier that prevents diffusion of adhesive molecules (or other polymer molecules mobile at ambient temperatures) into the nanofiber forest. These techniques can be applied to single layer nanofiber forests or stacks of multiple nanofiber forest. By selecting the bond strength between the nanofiber forest and the transfer films, the nanofibers can be aligned in a common direction that includes, but is not limited to, perpendicular to a substrate or transfer film.

Abstract: A neural network system for summarizing source code is described. The neural network system includes one or more computers and one or more non-transitory computer storage media storing instructions that, when executed by the one or more computers, cause the one or more computers to implement: a heterogeneous code representation (HCR) generator; a sub-system; a Transformer encoder neural network; a tree-based encoder neural network; a heterogeneous graph transformer (HGT) neural network; and a graph aggregator. In some implementations, the neural network system includes one or more of a token index selector, a hierarchy-aware cross attention neural network layer, a gating neural network layer, and a Transformer decoder neural network.

Abstract: A tailgate pad. The tailgate pad includes a front side. The tailgate pad also includes a back side. The tailgate pad further includes a fold out panel coupled with the front side, the fold out panel to wrap about at least a portion of a wheel of a vehicle.

Abstract: Provided are a multi-function device for intensive shrimp farming and intensive shrimp farming systems using this device. The system comprises: shrimp ponds (100) with brackish water pumped from rivers or seas then treated with chemicals, sedimentation and micro-organisms; at least one multifunction device (200) to generate water flow, dissolve molecular oxygen, deliver and dispense shrimp feed and provide solution containing minerals, micro-organisms and other additives; pure oxygen supply device (300) capable of generating oxygen from the air to supply oxygen with purity higher than 90% to water in intensive culture pond to achieve consistently higher concentrations of dissolved oxygen saturated dissolved oxygen concentration; a network of porous sheets floats on the water to reduce the diffusion of oxygen molecules from the water to the air; and a network of lights for providing artificial light to change the feeding cycle of shrimp with industrial and natural food.

Abstract: A drug packaging device includes a drug accommodating/dispensing unit that supplies various types of drugs, a drug packaging portion in which a drug supplied from the drug accommodating/dispensing unit is packaged in a packaging sheet, a drug packaging introducing member that drops the drug to be packaged into the packaging sheet in the drug packaging portion), a pooling portion that pools, upstream of this drug packaging introducing member, the drug, and a drug imaging device that captures an image of the drug in the pooling portion. The drug imaging device performs an imaging process of capturing an image of the drug in the pooling portion in a non-backlit state, and an imaging process of capturing an image of the drug in the pooling portion in a backlit state.

Abstract: An approach is disclosed herein to sequence selection in a UVM environment. Generally, this approach includes a training phase for each machine learning model of a plurality of machine learning models. Each model is trained to achieve a particular target state and is rewarded when a selected action or sequence of actions causes movement that might be beneficial to achieving that target state. Once a respective model is trained, the trained model can then be used to determine which one action or sequence of actions (or ordered multiple thereof) to take to achieve the corresponding target state. Thus, by training and using a plurality of machine learning models to achieve a plurality of target states, and stimulating those machine learning models once trained, one or more actions and/or sequences of actions are generated as the selected sequences to be used to verify functionality or operation of a design under test.

Abstract: Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 1,4-BDO are disclosed. For example, genetically modified methanotrophs that are capable of generating 1,4-BDO at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed.

Abstract: Systems and methods for detecting and remediating roadway hazards are disclosed. A machine learning model is trained on a dataset related to roadway items. Input data is collected by a data collection engine and provided to a pattern recognizer. The pattern recognizer extracts roadway features and recognized patterns from the input data and provide the extracted features to a trained machine learning model. The trained model compares the extracted features to the model, and a risk value is generated. The risk value is compared to a risk value threshold. If the risk value is equal to or exceeds the risk threshold, then the input data may be classified as a roadway hazard. Remedial action is subsequently be triggered.

Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.

Abstract: The present invention is to provide a system for producing hydrogen gas, comprising: an electrolyte solution supply system, an electrolyzer, a hydrogen gas purification system, and a hydrogen gas compression and drying system. Wherein the electrolyte solution supply system operable to supply the electrolyte solution; the electrolyzer operable to perform the electrolysis creates hydrogen gas and oxygen gas; the hydrogen gas purification system operable to the purification of hydrogen gas; and the hydrogen gas compression and drying system operable to dry and compress hydrogen gas to a pressure of a predetermined value. In addition, the invention also mentions a method for producing hydrogen gas to produce hydrogen gas with a purity of more than 99.8%.

Abstract: Described herein are methods and apparatuses for cleaning a surgical scope, the apparatus comprising: a sheath for removably receiving a tube of the surgical scope, the sheath comprising: a wall defining a channel for receiving the tube, where a distal portion of the wall is configured to extend only partially around a circumference of the tube, a first conduit that defines a liquid flow path, and a second conduit that defines a gas flow path; and at least one nozzle located at a distal end of the distal portion of the wall and configured for directing a flow of liquid from the first conduit across a lens of the surgical scope and directing a flow of gas from the second conduit across the lens of the surgical scope to clear the liquid from the lens.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods for utilizing machine learning to generate a mask for an object portrayed in a digital image. For example, in some embodiments, the disclosed systems utilize a neural network to generate an image feature representation from the digital image. The disclosed systems can receive a selection input identifying one or more pixels corresponding to the object. In addition, in some implementations, the disclosed systems generate a modified feature representation by integrating the selection input into the image feature representation. Moreover, in one or more embodiments, the disclosed systems utilize an additional neural network to generate a plurality of masking proposals for the object from the modified feature representation. Furthermore, in some embodiments, the disclosed systems utilize a further neural network to generate the mask for the object from the modified feature representation and/or the masking proposals.

Abstract: Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of LRRK2 RNA in a cell or animal, and in certain instances reducing the amount of LRRK2 protein in a cell or animal. Such compounds, methods, and pharmaceutical compositions are useful to ameliorate at least one symptom or hallmark of a neurodegenerative disease. Such symptoms and hallmarks include ataxia, neuropathy, and aggregate formation. Such neurodegenerative diseases include Parkinson's disease.