Abstract: A variety of methods and compostions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.

Abstract: A compound having the structure set forth in Formula (I) and Formula (II): wherein the substituents Y, Z, A, B, R1, R2, R3, R4 and R5 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity.

Abstract: A method for vehicle-to-vehicle identification and detection and a system for the same are revealed. A plurality of radio frequency (RF) communication units with different communication directions is arranged at a vehicle body. Each RF communication unit sends identification information of the vehicle to nearby vehicles in response to communication requests from the nearby vehicles. The vehicle sends communication requests to the nearby vehicles in different communication directions by antennas of the RF communication units using time-sharing polling or simultaneous communication scheme. Thus RF communication between vehicles is achieved for identification and detection of the nearby vehicles. The precise and accurate positioning of the respective vehicle within the area is achieved to support vehicle active safety control or provide data required for autonomous driving for improving driving safety.

Abstract: The invention is directed to a polyester comprising 5-furandicarboxylic acid moieties (A); ethylene glycol moieties (B); 1,4:3,6-dianhydrohexitol moieties (C); alicyclic diol moieties other than the 1,4:3,6-dianhydrohexitol moieties (D); wherein the molar ratio (B)/[(B)+(C)+(D)] is greater than 0.2. The invention aloes relates to a process of preparing the polyester and to its use.

Abstract: Systems and methods for integrating ultra-fast programmable networks in microgrid are disclosed to provide flexible and easy-to-manage communication solutions, thus enabling resilient microgrid operations in face of various cyber and physical disturbances. The system is configured to establish a novel software-defined networking (SDN) based communication architecture which abstracts the network infrastructure from the upper-level applications to significantly expedite the development of microgrid applications, develop three functions of the SDN controller for microgrid emergency operations, including time delay guarantee, failover reconfiguration and rate limit and create a hardware-in-the-loop cyber-physical platform for evaluating and validating the performance of the presented architecture and control techniques.

Abstract: A compound having the structure set forth in Formula (I) and Formula (II): wherein the substituents Y, Z, A, B, R1, R2, R3, R4 and R5 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions associated with a PTEN deficiency that are ameliorated by the inhibition of PARP activity.

Abstract: A touch panel and a touch display device are provided. The touch panel includes: a plurality of first touch electrode patterns comprising first touch units and a connection unit connecting two adjacent first touch units; second touch electrode patterns intersectedly insulated from the first touch electrode patterns, wherein the second touch electrode patterns includes independent second touch units, and at least one bridge structure connecting two adjacent second touch units. The bridge structure is provided with two bridge units. One bridge unit includes at least two metal bridges and a connecting portion connecting metal bridges. The metal bridges at both ends of the bridge unit are respectively lapped on the two adjacent second touch units. The other bridge unit only includes one metal bridge, and two ends of the metal bridge of the other bridge unit are respectively lapped on the two adjacent second touch units.

Abstract: A touch panel includes a plurality of first touch electrode patterns including a plurality of first touch units and a connection unit connecting two adjacent first touch units. The touch panel further includes a plurality of second touch electrode patterns insulated from and intersected with the first touch electrode patterns, and the second touch electrode patterns includes a plurality of second touch units and a bridge unit connecting two adjacent second touch units, and a plurality of bridge units are arranged along a preset direction and an intersection angle between the preset direction and the second direction is greater than 0° and less than 90°.

Abstract: One aspect of the invention provides a three-dimensional scaffold including at least one layer of highly-aligned fibers. The at least one layer of highly-aligned fibers is curved in a direction substantially perpendicular to a general direction of the fibers. Another aspect of the invention provides a method for fabricating a three-dimensional scaffold. The method includes: electro spinning a plurality of fibers to produce at least one layer of highly-aligned fibers and forming the at least one layer of highly-aligned fibers into a three-dimensional scaffold without disturbing the alignment of the highly-aligned polymer fibers. A further aspect of the invention provides methods for using a three-dimensional scaffold to treat nerve or spinal cord injury.

Abstract: A method of forming a multilayer structure for a pixelated display and a multilayer structure for a pixelated display is provided. The method comprising providing a first wafer comprising first layers disposed over a first substrate, said first layers comprising non-silicon based semiconductor material for forming p-n junction LEDs (light emitting devices); providing a second partially processed wafer comprising silicon-based CMOS (Complementary Metal Oxide Semiconductor) devices formed in second layers disposed over a second substrate, said CMOS devices for controlling the LEDs; and bonding the first and second wafers to form a composite wafer via a double-bonding transfer process.

Abstract: A method for vehicle-to-vehicle identification and detection and a system for the same are revealed. A plurality of radio frequency (RF) communication units with different communication directions is arranged at a vehicle body. Each RF communication unit sends identification information of the vehicle to nearby vehicles in response to communication requests from the nearby vehicles. The vehicle sends communication requests to the nearby vehicles in different communication directions by antennas of the RF communication units using time-sharing polling or simultaneous communication scheme. Thus RF communication between vehicles is achieved for identification and detection of the nearby vehicles. The precise and accurate positioning of the respective vehicle within the area is achieved to support vehicle active safety control or provide data required for autonomous driving for improving driving safety.

Abstract: Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme ceramide galactosyltransferase (CGT), such as, for example, lysosomal storage diseases. Examples of lysosomal storage diseases include, for example, Krabbe disease and Metachromatic Leukodystrophy.

Abstract: The present application provides a method, an apparatus and a system for establishing biometric identification information transmission and a storage medium, including: transmitting a first random number to a driving unit; receiving a second random number and a first identity verification information from the driving unit; generating a key of a first session according to the first random number, the second random number and a pre-shared key, and generating a second identity verification information according to the key of the first session, the first random number and the second random number; transmitting the second identity verification information to the driving unit; and determining, according to the first identity verification information and the second identity verification information, whether a session between a biometric identification apparatus and the driving unit is established successfully. Therefore system overheads is reduced.

Abstract: Embodiments of the invention relate to concrete admixtures, provide a phosphonato block polymer, a preparation method and an application. The method includes: the phosphonato block polymer prepared by copolycondensating an ether-type segment A, a phosphonato segment B, and a third part of aldehyde C. The ether-type segment A is obtained by polycondensating a polyether monomer and a first part of aldehyde C. The phosphonato segment B is obtained by polycondensating a monomer b containing phosphonato, a monomer c, and a second part of aldehyde C in an aprotic weak polar solvent E. By preparing a block polymer using arylalkane as a main chain and using a phosphonic acid or phosphinic acid functional group as an adsorption group, the invention improves the resistance of the block polymer to sulfate and clay interference, and can achieve initial high dispersion of concrete with a low water-cement ratio and decreasing of the system viscosity.

Abstract: A variety of methods and compositions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.

Abstract: A one-button power-on processing method and a terminal thereof are provided. The method includes: judging whether pressing a power button at a current time triggers one-button power-on of a terminal when it is detected that the power button is pressed at the current time; and sending the biometric feature data acquired by the biometric feature identification module to an operating system of the terminal for one-button power-on processing if pressing the power button at the current time triggers one-button power-on of the terminal. In this way, the terminal is powered on by a user by performing the press operation once. This enhances convenience, and effectively improves user experience of the terminal.

Abstract: Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).

Abstract: A touch display panel and a touch display device. The touch display panel includes a cathode and a number of touch electrodes. The cathode includes at least one excavated area. The position of cathode corresponds to that of the touch electrode, thereby reducing the relative area between the cathode and the touch electrode.

Abstract: The fingerprint-based login method includes: waking up an operating system of a terminal device where a fingerprint sensor is disposed based on a detected non-press-type touch operation against the fingerprint sensor; controlling the fingerprint sensor to acquire fingerprint data based on a fingerprint data acquisition instruction sent by the waken-up operating system; storing the acquired fingerprint data to a designated security region in the terminal device by the waken-up operating system; and judging whether the fingerprint data stored in the designated security region matches fingerprint password data by the waken-up operating system upon detecting a press-type touch operation against the fingerprint sensor, such that a login operation is performed in the operating system if the stored fingerprint data matches the fingerprint password data, the problem that the fingerprint modules using the conventional MCUs failing to satisfy the requirements may not implement the system login function is effectively s

Abstract: Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).