Abstract: A process for producing phenol and methyl ethyl ketone comprises contacting benzene and a C4 alkylating agent under alkylation conditions and in the presence of an alkylation catalyst comprising at least one molecular sieve of the MCM-22 family to produce an alkylation effluent comprising secbutylbenzene; wherein the contacting is conducted in a plurality of reaction zones and the C4 alkylating agent secbutylbenzene fraction is recovered from the alkylation effluent and comprises at least 95 wt % sec-butylbenzene, less than 100 wt ppm of C8+ olefins, and less than 0.5 wt % of isobutylbenzene and tert-butylbenzene. The sec-butylbenzene fraction is then oxidized to produce sec-butylbenzene hydroperoxide and the hydroperoxide is cleaved to produce phenol and methyl ethyl ketene.

Abstract: A process for producing phenol and methyl ethyl ketone comprises contacting benzene and a C4 olefin under alkylation conditions and in the presence of an alkylation catalyst to produce an alkylation effluent comprising sec-butylbenzene and C8+ olefins. The alkylation effluent is then treated to reduce the amount of said C8+ olefins and produce a treated effluent, whereafter the sec-butylbenzene in the treated effluent is oxidized to produce a hydroperoxide and the hydroperoxide is cleaved to produce phenol and methyl ethyl ketone.

Abstract: A substantially surface-deactivated catalyst composition that is stable at least to 300° C. The catalyst includes a zeolite catalyst (e.g., ZSM-22, ZSM-23, or ZSM-57) having active internal Brönsted acid sites and a surface-deactivating amount of a rare earth or yttrium oxide (e.g., chosen from lanthanum oxide or lanthanides oxide). This to catalyst is preferably used in a process for producing a higher olefin by oligomerizing a light olefin, wherein the process includes contacting a light olefin under oligomerization conditions with the substantially surface-deactivated catalyst composition.

Abstract: Disclosed herein is a process and catalyst for producing a monoalkylated aromatic compound from a polyalkylated aromatic compound, comprising the step of contacting an alkylatable aromatic compound with a polyalkylated aromatic compound under at least partial liquid phase conditions in the presence of a zeolite beta catalyst having a phosphorus content in the range of 0.001 wt. % to 10.0 wt. % of said catalyst, to provide a product which comprises a monoalkylated aromatic compound.

Abstract: A process for oligomerizing isobutene includes contacting a feedstock including isobutene with a catalyst comprising an EMM-10 molecular sieve under conditions effective to oligomerize said isobutene and produce an effluent containing less isobutene than the feedstock.

Abstract: In a process for producing cyclohexylbenzene, benzene and hydrogen are fed to at least one reaction zone. The benzene and hydrogen are then contacted in the at least one reaction zone under hydroalkylation conditions with a catalyst system comprising a molecular sieve having an X-ray diffraction pattern including d-spacing maxima at 12.4±0.25, 6.9±0.15, 3.57±0.07 and 3.42±0.07 Angstrom, and at least one hydrogenation metal to produce an effluent containing cyclohexylbenzene. The ratio of the total number of moles of hydrogen fed to said at least one reaction zone to the number of moles of benzene fed to said at least one reaction zone is between 0.4 and 0.9:1.

Abstract: A substantially surface-deactivated catalyst composition that is stable at least to 300° C. The catalyst includes a zeolite catalyst (e.g., ZSM-22, ZSM-23, or ZSM-57) having active internal Brönsted acid sites and a surface-deactivating amount of a rare earth or yttrium oxide (e.g., chosen from lanthanum oxide or lanthanides oxide). This catalyst is preferably used in a process for producing a higher olefin by oligomerizing a light olefin, wherein the process includes contacting a light olefin under oligomerization conditions with the substantially surface-deactivated catalyst composition.

Abstract: In a process for producing cyclohexylbenzene, benzene and hydrogen are fed to at least one reaction zone. The benzene and hydrogen are then contacted in the at least one reaction zone under hydroalkylation conditions with a catalyst system comprising a molecular sieve having an X-ray diffraction pattern including d-spacing maxima at 12.4±0.25, 6.9±0.15, 3.57±0.07 and 3.42±0.07 Angstrom, and at least one hydrogenation metal to produce an effluent containing cyclohexylbenzene. The catalyst system has an acid-to-metal molar ratio of from about 75 to about 750.

Abstract: A patient positioning system for use with a radiation therapy system that monitors the location of fixed and movable components and pre-plans movement of the movable components so as to inhibit movement if a collision would be indicated. The positioning system can also coordinate movement of multiple movable components for reduced overall latency in registering a patient. The positioning system includes external measurement devices which measure the location and orientation of objects, including components of the radiation therapy system, in space and can also monitor for intrusion into the active area of the therapy system by personnel or foreign objects to improve operational safety of the radiation therapy system.

Abstract: The present invention relates to novel Anilinopiperazine Derivatives of formula (I), compositions comprising the Anilinopiperazine Derivatives, and methods for using the Anilinopiperazine Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease, a fungal infection, or a disorder related to the activity of a protein kinase.

Abstract: The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I wherein A1, A2, A3, A4, A5, A6, T1, T2, W, X, Y and Z of Formula I are defined herein. The invention also includes use of these compounds in pharmaceutical compositions for treatment, prophylactic or therapeutic, of disorders and conditions related to the activity of beta-secretase protein. Such disorders include, for example, Alzheimer's Disease, cognitive deficits, cognitive impairment, schizophrenia and other central nervous system conditions related to and/or caused by the formation and/or deposition of plaque on the brain. The invention also comprises further embodiments of Formula I, intermediates and processes useful for the preparation of compounds of Formula I.

Abstract: An adjustable immobilizing joint brace has a pair of opposed, spaced apart first supports for supporting and immobilizing a joint. Each first support has a pair of first joint holes proximate a first end. One of the first joint holes is spaced further from the first end of the first support than the other first joint hole. A pair of opposed, spaced apart second supports has two opposed sides. Each second support has a pair of second joint holes proximate a joint end. The second joint holes are aligned with and attached to the first joint holes on either side of the first support such that the first supports are attached to the second supports and form a variable angle which depends on the orientation of the first supports relative to the orientation of the second supports.

Abstract: In a process for producing a hydrocarbon composition, a feed comprising at least one C3 to C8 olefin and an olefinic recycle stream rich in C9? hydrocarbons is contacted with a crystalline molecular sieve catalyst having an average crystal size no greater than 0.05 micron and an alpha value between about 100 and about 600 in at least one reaction zone under olefin oligomerization conditions including an inlet temperature between about 150° C. and about 350° C., a pressure of at least 2,860 kPa and a recycle to feed weight ratio of about 0.1 to about 3.0. The contacting produces an oligomerization effluent stream, which is separated into at least a hydrocarbon product stream rich in C9+ hydrocarbons and the olefinic recycle stream.

Abstract: The present invention relates to novel Anilinopiperazine Derivatives of formula (I), compositions comprising the Anilinopiperazine Derivatives, and methods for using the Anilinopiperazine Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease, a fungal infection, or a disorder related to the activity of a protein kinase.

Abstract: An alkylaromatic hydrocarbon composition prepared by the process which comprises oligomerizing an olefin selected from the group consisting of propylene, n-butene and mixtures thereof over an oligomerization catalyst, to form a oligomerization product comprising at least 95% by weight of mono-olefin oligomers of the empirical formula: CnH2n wherein n is greater than or equal to 10, the mono-olefin oligomers comprise at least 20% by weight of olefins having at least 12 carbon atoms, and the olefins having at least 12 carbon atoms having an average of from 0.8 to 2.0 C1-C3 alkyl branches per carbon chain. Sulfonation of the alkylaromatic hydrocarbon product produces an alkylaryl sulfonate mixture that exhibits advantageous properties, such as biodegradability and hard and cold water performance.

Abstract: A semiconductor substrate includes semi-insulating portions beneath openings in a patterned hardmask film formed over a semiconductor substructure to a thickness sufficient to prevent charged particles from passing through the hardmask. The semi-insulating portions include charged particles and may extend deep into the semiconductor substrate and electrically insulate devices formed on opposed sides of the semi-insulating portions. The charged particles may advantageously be protons and further substrate portions covered by the patterned hardmask film are substantially free of the charged particles.

Abstract: A process for producing sec-butylbenzene comprises contacting a feed comprising benzene and a C4 alkylating agent under alkylation conditions comprising a temperature of about 110° C. to about 150° C. with a catalyst comprising at least one molecular sieve having an X-ray diffraction pattern including d-spacing maxima at 12.4±0.25, 6.9±0.15, 3.57±0.07 and 3.42±0.07 Angstrom. The sec-butylbenzene can be then oxidized to produce a hydroperoxide and the hydroperoxide decomposed to produce phenol and methyl ethyl ketone.

Abstract: A process for producing phenol and methyl ethyl ketone comprises contacting benzene and a C4 olefin under alkylation conditions and in the presence of an alkylation catalyst to produce an alkylation effluent comprising sec-butylbenzene and C8+ olefins. The alkylation effluent is then treated to reduce the amount of said C8+ olefins and produce a treated effluent, whereafter the sec-butylbenzene in the treated effluent is oxidized to produce a hydroperoxide and the hydroperoxide is cleaved to produce phenol and methyl ethyl ketone.

Abstract: In a process for preparing an alkylaromatic hydrocarbon composition an olefinic hydrocarbon mixture and an aromatic compound are contacted under alkylation conditions with an aromatic alkylation catalyst selected from a homogeneous acid catalyst and heterogeneous acid catalyst comprising a molecular sieve having an X-ray diffraction pattern including d-spacing maxima at 12.4±0.25, 6.9±0.15, 3.57±0.07 and 3.42±0.07 Angstroms. The olefinic hydrocarbon mixture comprises at least 5 wt % by weight of mono-olefin oligomers of the empirical formula: CnH2n wherein n is greater than or equal to 10, the mono-olefin oligomers comprising at least 20 percent by weight of olefins having at least 12 carbon atoms, and the olefins having at least 12 carbon atoms having an average of from 0.8 to 2.0 C1-C3 alkyl branches per carbon chain.