Abstract: Embodiments described herein relate to an envelope tracking system that uses a single-bit digital signal to encode an analog envelope tracking control signal, or envelope tracking signal for brevity. In certain embodiments, the envelope tracking system can estimate or measure the amplitude of the baseband signal. The envelope tracking system can further estimate the amplitude of the envelope of the RF signal. The system can convert the amplitude of the envelope signal to a single-bit digital signal, typically at a higher, oversample rate. The single-bit digital signal can be transmitted in, for example, a low-voltage differential signaling (LVDS) format, from a transceiver to an envelope tracker. An analog-to-digital converter (ADC or A/D) can convert the single-bit digital signal back to an analog envelope signal. Moreover, a driver can increase the power of the A/D output envelope signal to produce an envelope-tracking supply voltage for a power amplifier.

Abstract: A network configuration change validation environment is disclosed. In particular, this disclosure is related to an interface to initiate automated test actions (e.g., network monitoring commands, application monitoring commands, etc.) and to view results in an efficient manner to support a network communication infrastructure. In one example, results of a set of commands executed prior to a configuration change may serve as a baseline and one or more results of the same set of commands may be intelligently compared to the baseline to identify any potential issues that have arisen. For example, as a result of a specific network configuration change or application update. The disclosed network change validation command initiator and validation report viewer represent part of an overall network configuration change validation environment that includes automated techniques such that it may be used within a given change window.

Abstract: A low profile endocavity needle guide device for an ultrasonic probe is disclosed. The device includes a needle guide and a clamp assembly. The needle guide is a tubular member configured to enable an elongated needle to be extended through it. The clamp assembly includes a first clamp member, a second clamp member and a slidable member. The first clamp member is pivotable with respect to the second clamp member between an engagement position and a release position, and vice versa. The slidable member is mounted on the first clamp member and includes a low profile projection which engages a ramped surface of the first clamp member to pivot the first clamp member to the engagement position when the projection is slid up the ramped surface, and to enable the first clamp member to move to the release position when the projection is slid down the ramp surface.

Abstract: A network configuration change validation environment is disclosed. In particular, this disclosure is related to an interface to initiate automated test actions (e.g., network monitoring commands, application monitoring commands, etc.) and to view results in an efficient manner to support a network communication infrastructure. In one example, results of a set of commands executed prior to a configuration change may serve as a baseline and one or more results of the same set of commands may be intelligently compared to the baseline to identify any potential issues that have arisen. For example, as a result of a specific network configuration change or application update. The disclosed network change validation command initiator and validation report viewer represent part of an overall network configuration change validation environment that includes automated techniques such that it may be used within a given change window.

Abstract: A network configuration development environment including an insights enabled editor is disclosed. In particular, this disclosure is related to an editor that provides just-in-time information in an insights area to assist a network developer to configure parameter settings for one or more network devices. In one example, attributes of a switch are the area of focus of a current edit session, and, based on this area of focus, the insights editor may query the switch to obtain current information. Information returned from the switch may be provided in an “insights area” visible to the user about to edit settings for that same switch. The disclosed insights editor represents part of an overall network configuration development environment that includes automated techniques to assist with network configuration, design and maintenance.

Abstract: The invention features methods of treating melanoma by modulating an activity of GDF6 in melanoma cells. In one aspect, the methods involve downregulating an activity of GDF6, for example, by using an anti-GDF6 binding molecule, such as an inactivating antibody. Another aspect features treating a subject by first screening for the presence of GDF6 and then treating the subject with an inhibitor of a GDF6 activity. Screening assays for identification of modulators of an activity of GDF6 are also featured.

Abstract: The present invention makes use of a modular Folded Tubular Photometer to measure the concentrations of gas-phase species and/or particles, including especially air pollutants such as ozone (O3), nitrogen dioxide (NO2), sulfur dioxide (SO2) and black carbon particulate matter, by means of absorbance of ultraviolet (UV), visible or infrared (IR) light. The optical bench makes use of modular components (tubes and mirror assemblies) that allow construction of path lengths of up to 2 meters or more while maintaining low detection cell volumes. The long path lengths, low cell volumes, and the innovation of pressure equalization during the absorbance measurements enable sensitive detection of ambient air pollutants down to low part-per-billion levels or less for gas species, and extinctions down to 1 Mm?1 or less for particulate matter, corresponding to ˜0.13 ?g/m3 or less for black carbon particulates.

Abstract: A spray tip comprises a tip body, a tip piece, and a pre-orifice piece. The tip body has a fluid channel along a channel axis (AC). The tip piece is disposed within the fluid channel, and has a stepped, narrowing passage that terminates in an outlet orifice. The pre-orifice piece has an inlet passage, and is disposed within the fluid channel, abutting and immediately upstream of the tip piece. The pre-orifice piece and the tip piece together define a turbulating chamber therebetween.

Abstract: An adjustable trip assembly is for an electrical switching apparatus. The electrical switching apparatus includes a housing, separable contacts and an operating mechanism for opening and closing the separable contacts. The adjustable trip assembly includes a load conductor, a magnetic assembly comprising a magnetic member and an armature movably coupled to the magnetic member, and a calibration assembly comprising a calibration bracket cooperating with the armature, and an adjustment mechanism being adjustable to move the calibration bracket and thereby adjust the position of the armature with respect to the magnetic member to calibrate the magnetic assembly. The magnetic assembly further includes a biasing element that biases the armature away from the magnetic member.

Abstract: A needle guide to retain a needle at a desired trajectory with respect to an imaging transducer includes a body member, a needle holder subassembly, and a slide member. The needle holder subassembly is pivotably mounted on the body member to enable the needle holder subassembly to be oriented to various selected orientations with respect to the body member. The slide member is slidably coupled to each of the body member and the needle holder subassembly, such that movement of the slide member relative to the body member moves the needle holder subassembly between the various selected orientations.

Abstract: In embodiments, systems and methods may involve using a platform as disclosed herein for applications described herein where the systems and methods involve receiving a dataset in an analytic platform, the dataset including fact data and dimension data for a plurality of distinct product categories. It may also involve storing the data in a flexible hierarchy, the hierarchy allowing the temporary fixing of data along a dimension and flexible querying along other dimensions of the data. It may also involve pre-aggregating certain combinations of data to facilitate rapid querying, the pre-aggregation based on the nature of common queries. It may also involve facilitating the presentation of a cross-category view of an analytic query of the dataset. In embodiments, the temporarily fixed dimension can be rendered flexible upon an action by the user.

Abstract: A front end module having transmit loopback functionality may be operated by conducting a loopback signal from an output of a power amplifier to a receive port on a transmit loopback path and conducting a radio frequency receive signal from an antenna port to the receive port on a receive path. The transmit loopback path includes a first switch coupled between the output of the power amplifier and the receive port. The receive path includes a second switch coupled between the antenna port, where the receive port and is without the first switch.

Abstract: An adaptor for mounting on an imaging transducer includes a hollow housing configured to receive a portion of the imaging transducer. The housing comprises a coupling member for enabling releasable securement of a needle guide device to the housing, wherein the needle guide device includes a body member and a lockable mounting member. The coupling member comprises a projection portion that projects outwardly from the housing, wherein the projection portion includes first and second undercut recesses on opposing sides of the projection portion, wherein the projection portion is configured for receipt in a recess in the body member, the recess in the body member including at least one stop portion.

Abstract: An imaging transducer comprises a housing that includes a coupling member for enabling the releasable securement of a needle guide device to the housing, wherein the needle guide device includes a body member and a lockable mounting member. The coupling member comprises a projection portion that projects outwardly from the housing, wherein the projection portion includes first and second undercut recesses on opposing sides of the projection portion. The projection portion is configured for receipt in a recess in the body member, the recess in the body member including at least one stop portion, wherein the first undercut recess is configured to receive the stop portion.

Abstract: A spray tip (22) comprises a tip body (100), a tip piece (102), and a pre-orifice piece (104). The tip body has a fluid channel (114) along a channel axis (Ac). The tip piece is disposed within the fluid channel, and has a stepped, narrowing passage (124) that terminates in an outlet orifice (24). The pre-orifice piece has an inlet passage (112), and is disposed within the fluid channel, abutting and immediately upstream of the tip piece. The pre-orifice piece and the tip piece together define a turbulating chamber (106) therebetween.

Abstract: A needle guide device for releasable mounting on an imaging transducer or on an adaptor bracket on an imaging transducer is disclosed. The needle guide device includes a universal lockable mounting member which is configured for slidable releasable engagement with a coupling member on a specially constructed imaging transducer or on a conventional imaging transducer onto which a specially constructed adaptor is mounted. The needle guide device makes use of a slidable mounting member to cooperate with the coupling member. The needle guide device is adjustable to establish various selectable angular trajectories for a needle and has a low profile form factor to result in the creation of a minimal blind zone when mounted on the transducer and even if establishing a large angle for shallow needle penetration.

Abstract: An arrangement of acoustic transducers for a flow meter. The flow meter is for measuring the rate at which fluid is flowing. The arrangement includes a respective transducer set for each edge of a notional regular polygon. The transducer sets are associated with a tubular cavity for carrying the fluid. Each of the transducer sets respectively includes two acoustic transducers oriented to define an acoustic path lying in a measurement plane of the respective set, and another two acoustic transducers oriented to define another acoustic path lying in the measurement plane of the respective set. The transducers sets are positioned so that, in a cross-section normal to the tubular cavity, the measurement plane of each respective transducer set is coincident with a respective edge of the notional regular polygon.

Abstract: Embodiments described herein relate to an envelope tracking system that uses a single-bit digital signal to encode an analog envelope tracking control signal, or envelope tracking signal for brevity. In certain embodiments, the envelope tracking system can estimate or measure the amplitude of the baseband signal. The envelope tracking system can further estimate the amplitude of the envelope of the RF signal. The system can convert the amplitude of the envelope signal to a single-bit digital signal, typically at a higher, oversample rate. The single-bit digital signal can be transmitted in, for example, a low-voltage differential signaling (LVDS) format, from a transceiver to an envelope tracker. An analog-to-digital converter (ADC or A/D) can convert the single-bit digital signal back to an analog envelope signal. Moreover, a driver can increase the power of the A/D output envelope signal to produce an envelope-tracking supply voltage for a power amplifier.

Abstract: A cover for an ultrasound scanning assembly is provided, wherein the cover exerts compressive force on the patient during use. The cover includes an outer frame and a nonporous or porous film extending across the outer frame. The outer frame is formed of a soft touch material.

Abstract: A front end module having transmit loopback functionality may be operated by conducting a loopback signal from an output of a power amplifier to a receive port on a transmit loopback path and conducting a radio frequency receive signal from an antenna port to the receive port on a receive path. The transmit loopback path includes a first switch coupled between the output of the power amplifier and the receive port. The receive path includes a second switch coupled between the antenna port, where the receive port and is without the first switch.