Patents by Inventor David

David has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITIONS AND METHODS OF ADMINISTRATION
    Publication number: 20250144046
    Abstract: The present disclosure describes novel compounds and compositions and methods of making and using thereof related that are capable of inhibiting PAK1 and associated diseases or disorders, including tumors and cancerous cells. The inventive compounds are more efficacious and stable than IPA-3 without needing liposomal formulations as vehicles for the compounds.
    Type: Application
    Filed: January 27, 2023
    Publication date: May 8, 2025
    Inventors: David CRICH, Somanath SHENOY, Brian CUMMINGS, Harvey D. HOMAN, Daniel A. GESELOWITZ
  • BUILDING INTEGRATED PHOTOVOLTAIC SYSTEMS
    Publication number: 20250150021
    Abstract: A system includes first, second and third photovoltaic modules on a rood. Each module includes an upper edge, a lower edge and at least one solar cell. Lower edges of the cells of the first and second modules are offset from lower edges of the first and second modules. Upper edge of the cell of the second module is offset from the upper edge of the second module. The upper edge of the cell of the third module is offset from the upper edge of the third module. The first module overlays the second module. The lower edge of the cell of the first module is substantially aligned with the upper edge of the cell of the second module. The second module overlays the third module. The lower edge of the cell of the second module is substantially aligned with the upper edge of the cell of the third module.
    Type: Application
    Filed: January 9, 2025
    Publication date: May 8, 2025
    Inventors: Natasha Hjerrild, David Kavulak, Richard Perkins, Gabriela Bunea, William Holt
  • HIDDEN FASTENER FREE DECK CLIP
    Publication number: 20250146304
    Abstract: Fastener-free deck clips, methods of use, and associated installation tools. The clips use a gripping element to secure the clip to a joist and do not require the use of a separate screw or other fastener, simplifying the installation process. The clip has a central body with lateral wings extending to an endpoint, where the gripping element is located. The gripping element may include puncturing elements to adhere better to the joist. Likewise, the main body may have tabs that can be depressed to further adhere to the joist. The clips may be installed by use of a handheld tool.
    Type: Application
    Filed: November 4, 2024
    Publication date: May 8, 2025
    Inventors: Andrew E. Reed, Christopher D. Hageman, David Mathieu, John Jason Roxburgh
  • INDUCTION-BASED HEAT RETENTIVE SERVER
    Publication number: 20250143514
    Abstract: A heat retentive server includes a chamber defined between an upper shell and a lower shell that are connected to one another. An induction-heatable member is positioned in the chamber, and the induction-heatable member may be heated by electromagnetic induction to a first temperature that is greater than the heat deflection temperature of the upper shell. Buffering material is positioned in the chamber between the induction-heatable member and the upper shell, and the buffering material is adapted for providing predetermined conductive heat transfer from the induction-heatable member to the upper shell so that at least a portion of the upper shell is heated to a second temperature that is greater than the heat deflection temperature of the upper shell. The second temperature is less than the first temperature.
    Type: Application
    Filed: January 10, 2025
    Publication date: May 8, 2025
    Applicant: Aladdin Temp-Rite, LLC
    Inventors: Rodger D. Crocker, David R. Gordon, R. Kevin Ray, Timothy D. Altizer, Matthew J. McCartney, Martin A. Rothschild, Philip H. Scruggs
  • PARTIAL SUBDIVISION SURFACES
    Publication number: 20250148719
    Abstract: Systems, methods, and non-transitory computer-readable media can determine data associated with a mesh of a three-dimensional object and generate a partially subdivided mesh based on the mesh and the data.
    Type: Application
    Filed: March 12, 2024
    Publication date: May 8, 2025
    Inventor: Lawrence David Cutler
  • SYSTEMS AND METHODS FOR PROCESSING OF FUNDUS IMAGES
    Publication number: 20250143562
    Abstract: Systems and methods for determining one or more recommendations for management of wellbeing of an individual are disclosed. An indication of relative cardiovascular aging of the individual is determined based at least in part on a predicted risk of cardiovascular disease (CVD) of the individual determined by a deep learning model based on one or more fundus images. The recommendations for management of the individual's wellbeing are based at least in part on a determined difference between the actual chronological age of the individual and an indication of relative cardiovascular aging of the individual.
    Type: Application
    Filed: January 10, 2025
    Publication date: May 8, 2025
    Inventors: Seyed Ehsan VAGHEFI REZAEI, David Michael SQUIRRELL, Song YANG, Songyang AN, Li XIE
  • Serotonin Receptor Agonists and Methods of Making and Using the Same
    Publication number: 20250145638
    Abstract: The present application relates to serotonin receptor agonists, including azepino compounds, as well as methods of using them for treating and preventing a variety of conditions.
    Type: Application
    Filed: December 21, 2022
    Publication date: May 8, 2025
    Applicant: Kuleon LLC
    Inventor: David Gilles
  • HYBRID-ELECTRIC PROPULSION SYSTEM EQUIPPED WITH A COUPLER FOR SWITCHING BETWEEN MODES OF OPERATION
    Publication number: 20250145301
    Abstract: A propulsion assembly includes a first torque source coupled with a first shaft and a second torque source coupled with a second shaft. A coupler selectively couples the first and second torque sources. When the first and second torque sources are coupled via the coupler, in response to a command to decouple the first torque source, an unloading operation is performed to decrease the torque output provided by the first torque source to a threshold, and when reached, the first shaft is decoupled from the coupler. When the first torque source is coupled with the coupler but the second torque source is not, in response to a command to couple the second torque source, a speed matching operation is performed to increase the speed of the second shaft to match a speed of the first shaft, and when the speeds are matched, the second shaft is coupled to the coupler.
    Type: Application
    Filed: July 13, 2023
    Publication date: May 8, 2025
    Inventors: Darek Tomasz Zatorski, Kurt David Murrow, Paul Robert Gemin, Philip M. Cioffi, John Russell Yagielski
  • MULTIDRUG PAIN MANAGEMENT PACKAGE
    Publication number: 20250144052
    Abstract: Disclosed herein is a multidrug pain management package to dispense two or more medicaments to treat pain comprising a primary n-polygon, and one or more concentric m-polygons, wherein each side of the n-polygon and m-polygons have at least n or m-medicament chambers capable of holding the two or more medicaments. Also disclosed herein is a multidrug pain management package comprising a disk, wherein the disk is divided into equally spaced regions, and wherein each region has chambers capable of holding medicaments. Also disclosed herein are single formulations to treat pain.
    Type: Application
    Filed: January 10, 2025
    Publication date: May 8, 2025
    Inventors: David L. STEINBERG, Joseph LOSKOVE, Hannah THOMPSON
  • RECYCLED CONTENT MONOETHYLENE GLYCOL
    Publication number: 20250145553
    Abstract: Recycled content monoethylene glycol (r-MEG) is produced using a process and system that applies physical and/or credit-based recycled content from one or more feed materials to the MEG produced from the feed materials. Recycled content diethylene glycol (DEG) can be formed in a similar manner.
    Type: Application
    Filed: February 14, 2023
    Publication date: May 8, 2025
    Applicant: Eastman Chemical Company
    Inventors: Daryl Bitting, David Eugene Slivensky, Xianchun Wu
  • LIQUID DIFFUSING DEVICE AND CARTRIDGE AND FLUID COMBINER FOR USE THEREWITH
    Publication number: 20250144263
    Abstract: A liquid diffusing device comprising: at least two cartridge receiving portions, each configured for removably receiving a cartridge configured to contain a liquid to be diffused, and having a respective pressurized air inlet associated therewith and configured to be in fluid communication with a cartridge inlet when the cartridge is positioned in the cartridge receiving portion; a pumping mechanism configured to generate pressurized air; and a selection mechanism configured to selectively establish a fluid communication between the pumping mechanism and the pressurized air inlet of one of the cartridge receiving portions for the pumping mechanism to pump the pressurized air into the respective cartridge for diffusing the liquid contained therein and generating an aerosol flow.
    Type: Application
    Filed: January 26, 2023
    Publication date: May 8, 2025
    Inventors: Avner Sadot, Ori Jacobi, Eviatar Ben David, Elad Shalom
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20250145634
    Abstract: The present disclosure relates to compounds that are capable of penetrating the blood brain barrier to modulate the activity of EGFR tyrosine kinase. The disclosure further relates to methods of treating glioblastoma and other EGFR-mediated cancers, such as those that have been determined to have altered glucose metabolism in the presence of inhibitors. The present disclosure also provides methods of administering to a subject a glucose metabolism inhibitor and a cytoplasmic p53 stabilizer.
    Type: Application
    Filed: June 12, 2024
    Publication date: May 8, 2025
    Inventors: David A. Nathanson, Michael E. Jung, Jonathan Tsang, Lorenz Urner, Peter M. Clark, Timothy F. Cloughesy, Gyudong Kim
  • DUAL MODE NEGATIVE PRESSURE SOURCE OPERATION FOR PROVISION OF NEGATIVE PRESSURE WOUND THERAPY
    Publication number: 20250144287
    Abstract: A negative pressure source can be fluidically connected to the wound dressing, the wound dressing can be positioned to cover at least a portion of the wound, and the negative pressure source can be controlled to supply negative pressure to the wound via the fluid flow path. An actuator of the negative pressure source can be controlled to operate in a dual mode by transitioning between a proportional-integral (PI) control or proportional-integral-derivative (PID) control and a pulsed control. Stalling of the actuator can be prevented, and therapy can be provided without interruptions.
    Type: Application
    Filed: January 10, 2025
    Publication date: May 8, 2025
    Inventors: Ben Alan Askem, David Michael Elder
  • Systems and Methods for Fault Location in Electrical Power Line Systems
    Publication number: 20250147092
    Abstract: A method for estimating fault location in an electrical power line system (PLS) is provided. The method includes receiving an observed signal caused by a real fault in the PLS. The observed signal is measured at a real observation point in the PLS. The real fault has occurred at one of two or more real locations in the PLS; accessing a library representing model signals between model guessed fault locations and a model observation point in a network model of the PLS; selecting a model GFL by: (i) calculating metrics for the model signals by processing the model signals with the observed signal, and/or (ii) selecting the model GFL corresponding to a highest calculated metric; estimating a fault location of real locations in the PLS based on a corresponding location of the selected model GFL; and sending the estimated fault location to an external management system.
    Type: Application
    Filed: February 10, 2023
    Publication date: May 8, 2025
    Applicant: Monash University
    Inventors: Reza Razzaghi, David Flynn, Lachlan Andrew
  • ADAPTIVE SPARK ENERGY CONTROL
    Publication number: 20250146465
    Abstract: A system and method for operating an ignition system. An ignition transformer has primary and secondary windings. A spark apparatus is connected with the secondary windings of the ignition transformer. One or more characteristics of a spark generated by the spark apparatus is provided. An electronic control unit is adapted to control the ignition transformer, such that, based on an identification of the spark using the one or more characteristics and the spark reference data, the electronic control unit sends control signals to the ignition transformer to modify the one or more characteristics of the spark. Modification of the one or more characteristics may occur in a same spark cycle as measurement of the one or more characteristics.
    Type: Application
    Filed: November 6, 2024
    Publication date: May 8, 2025
    Inventors: David LEPLEY, Matthew TRAINA, Aaron PHIFER, Gary KLEINFELDER
  • Laminates and Method of Manufacture Thereof
    Publication number: 20250145864
    Abstract: A self-adhesive laminate material and method of manufacture thereof in which a water-soluble coating applied to a print-receptive coating on a first side of the material is transferred to an adhesive on a second side of the material. When the material is rolled up, the water-soluble coating transfers from the first side to the second side, thereby offering protection to the adhesive.
    Type: Application
    Filed: January 11, 2024
    Publication date: May 8, 2025
    Inventors: Bruce Michael Drew, Michael John Cooper, David Nicholas Edwards
  • Error Alert Encoding for Improved Error Mitigation
    Publication number: 20250147844
    Abstract: Error alert encoding for improved error mitigation is described. In one or more implementations, a system includes a processor configured to receive an encoded signal indicating a type of an error detected in a memory, and output one or more mitigation commands to mitigate the type of the error detected in the memory based on the encoded signal. In one or more implementations, a memory system includes a memory and a buffer. The buffer is configured to output an encoded signal indicating a type of an error detected in the memory.
    Type: Application
    Filed: November 1, 2024
    Publication date: May 8, 2025
    Applicant: Advanced Micro Devices, Inc.
    Inventors: Hing Yan To, Christopher Edward Cox, David Da-Wei Lin
  • EQUIPMENT FOR AND METHOD OF FIXING A MEDICAL DEVICE TO A PATIENT
    Publication number: 20250144373
    Abstract: A surgical guide tube (1), a kit comprising a surgical guide tube (1), a system comprising a surgical guide tube (1), a clamping unit comprising a surgical guide tube portion and a method of providing a vascular access to a vessel of a patient comprising the step of providing a surgical guide tube is provided. Therein, the surgical guide tube (1) comprises a body having a proximal end, a distal end and a guide lumen with a longitudinal axis, the guide lumen extending from the proximal end to the distal end of the body and configured for inserting a medical device, in particular a catheter of an intravascular blood pump, through the body (2). The surgical guide tube (1) further comprises a sideways extension (10) defining a planar surface (12a, 12b) which is configured for being attached to a fascia (26) of a patient between a vessel (24) of the patient and skin of the patient.
    Type: Application
    Filed: December 8, 2022
    Publication date: May 8, 2025
    Applicant: Abiomed Europe GmbH
    Inventors: Christoph Nix, Cristine Rodriguez Brimmers, David Schibilsky
  • Material Characterization Method
    Publication number: 20250143630
    Abstract: The invention provides a method for determining a property of a target area of a material, wherein the target area has a size selected from the range of 100 ?m2-100 mm2, wherein the method comprises: an exposure stage comprising providing a liquid jet to the target area, wherein the liquid jet has a jet velocity selected from the range of 2-150 m/s; a measurement stage comprising detecting a deformation of the material in the target area and providing a related signal; and an analysis stage comprising determining the property of the target area based on the related signal.
    Type: Application
    Filed: February 10, 2023
    Publication date: May 8, 2025
    Inventors: David Fernandez Rivas, Miguel Angel Quetzeri Santiago
  • ORCHESTRATED INTELLIGENT SUPPLY CHAIN OPTIMIZER
    Publication number: 20250148398
    Abstract: The present invention relates to systems and methods for intelligently optimizing supply chain is provided. In particular, the systems and methods provide the capability to configure supply chain systems so as to: balance between cost and service is optimised and profitability maximised; configure system parameters to respond to both current and future risks; ensure that variability is built into plans enabling maximised efficiency; and human error and bias are eliminated from the planning process such that pro-active rather than reactive behaviour becomes the norm.
    Type: Application
    Filed: November 15, 2024
    Publication date: May 8, 2025
    Inventors: David Michael Evans, Robert Derward Rogers