Abstract: Aspects of the subject disclosure may include, for example, monitoring status of a network configured to provide end-to-end delivery of services to priority user equipment authorized according to a prioritized class of service and other user equipment not authorized for the prioritized class of service. The prioritized class of service extends a reserved network capacity for end-to-end delivery of a service via first domain including first network slices and a second domain including second network slices. A network interruption compromising the reserved capacity is determined based on the monitored status and integration of an alternate group of slices into one of the first network domain, the second network domain, or both to replace the compromised group of slices, is orchestrated. Integration of the alternate group of slices restores reserved network capacity according to the prioritized class of service. Other embodiments are disclosed.

Abstract: A vehicle including a transceiver and a processor is disclosed. The transceiver may be configured to receive a charging station location. The processor is configured to determine that the vehicle is in a key-off mode. Responsive to determining that the vehicle is in the key-off mode, the processor may determine at least one of a vehicle State of Charge (SOC) level or a vehicle distance from the charging station location based on a current vehicle location. The processor may further determine that a predefined condition is met based on the at least one of the vehicle SOC level or the vehicle distance. Responsive to a determination that the predefined condition is met, the processor may select a vehicle feature from a plurality of vehicle features based on historical usage pattern of the plurality of vehicle features in the key-off mode, and enable a high-power mode of the vehicle feature.

Abstract: Methods, systems, and devices for a seat cooling system. The seat cooling system includes a fan configured to pull air through a seat in an inward flow direction and to push air through the seat in an outward flow direction and an electronic control unit (ECU) connected to the fan. The ECU is configured to control an HVAC device to direct conditioned air into a cabin of a vehicle. The ECU can be further configured to control the fan to pull at least a portion of the conditioned air through the seat in the inward flow direction when an internal temperature of the vehicle is greater than a first temperature threshold and control the fan to push at least a portion of the conditioned air through the seat in the outward flow direction when the internal temperature of the vehicle is less than a second temperature threshold.

Abstract: A gas turbine engine is provided having a turbomachine; a primary fan driven by the turbomachine; a secondary fan located downstream of the primary fan within the inlet duct, the gas turbine engine defining a thrust to power airflow ratio between 3.5 and 100 and a core bypass ratio between 0.1 and 10; and an airflow mixer assembly comprising: a low pressure duct positioned within the core cowl; a plenum extending along the circumferential direction located downstream of the low pressure duct and in fluid communication with the low pressure duct; an inner shroud located downstream of the plenum and downstream of the exhaust and in fluid communication with both the plenum and the exhaust; and an outer shroud located outward of the plenum along the radial direction and extending along the circumferential direction and along the axial direction over and downstream of the inner shroud.

Abstract: The invention provides compositions containing a stable crystalline form of brequinar and methods of making such composition. The invention also provides methods of using such compositions to treat a condition in a subject.

Abstract: Disclosed herein are compositions comprising modified oligonucleotides. In some embodiments, the oligonucleotide includes a hydrophobic moiety. In some embodiments, the oligonucleotide includes a vinyl phosphonate. In some embodiments, the oligonucleotide includes modified oligonucleotide sugars such as 2? modified ribose molecules. In some embodiments, the oligonucleotide includes modified internucleoside linkages such as phosphorothioate linkages. In some embodiments, the oligonucleotide includes an siRNA. In some embodiments, the siRNA comprises a duplex region with overhangs on either end.

Abstract: A plurality of message transceivers coupled with each other via a portion of an electronic communications network characterized by a transmission latency are each operative to perform an action on data transaction messages received thereby. Upon receipt by any of the plurality of message transceivers of a first augmented data transaction message transmitted thereto by another of the plurality of message transceivers, the receiving message transceiver is configured to delay performance of the action on the first augmented data transaction message for an amount of time based on an extent to which a defined amount of time exceeds a transmission time, resulting from the transmission latency of the portion of the electronic communication network via which the first augmented data transaction message was conveyed, of the first augmented data transaction message between the transmitting and receiving message transceivers when the transmission time is less than the defined amount of time.

Abstract: Systems and methods for proxy device orchestration as autonomous primary workspace are described. In an illustrative, non-limiting embodiment, an Information Handling System (IHS may be configured to provide a workspace orchestration service, the IHS comprising: a processor; and a memory coupled to the processor, the memory having program instructions stored thereon that, upon execution by the processor, cause the IHS to: communicate with a proxy peripheral device disposed at a location where one or more client IHSs have primary workspaces instantiable through the workspace orchestration service; and provide one or more files to the proxy peripheral device, where the proxy peripheral device is configured to instantiate a primary workspace based upon the one or more files in the absence of any of the one or more client IHSs at the location.

Abstract: A deformation detection device detects deformation of a display system, such as a head-mounted display (HMD). The deformation detection device employs one or more sensors configured to detect one or more variations in positional and angular relationships of sensors, displays, and/or other components of the HMD to determine deviations from an original configuration of the HMD. The deformation detection device stores the variations in the positional and angular relationships for subsequent use during a re-calibration process that restores the viewing experience on the HMD.

Abstract: An example operation includes one or more of determining an expected charging duration of an electric vehicle (EV) at a charging point, determining content preferences of an occupant associated with the EV, wherein the content preferences are based on profile data of the occupant associated with the occupant, and delivering content to the EV, based on the expected charging duration and the content preferences.

Abstract: Systems and methods for user steering through workspace orchestration are described. In an illustrative, non-limiting embodiment, an Information Handling System (IHS) may include a processor and a memory coupled to the processor, the memory having program instructions stored thereon that, upon execution by the processor, cause the IHS to: receive, at a local management agent from a workspace orchestration service, one or more files configured to enable the local management agent to instantiate a workspace based upon a workspace definition, where the workspace definition enables the workspace to communicate with a selected peripheral device.

Abstract: A multipoint relay (MPR) wireless network may include spaced apart nodes, with each node including wireless transceiver circuitry, beacon circuitry, and a controller coupled to the wireless transceiver circuitry and beacon circuitry. The controllers may be configured to operate the beacon circuitry to determine a respective link strength metric for each potential link between nodes, assign a set of nodes from among the plurality of nodes to function as gateway nodes and assign other individual nodes to communicate via respective gateway nodes based upon the respective link strength metrics to define the MPR network so that one-hop links have a strongest link strength metric, and operate the wireless transceiver circuitry for communications over the MPR network.

Abstract: A method for secure detection of online fraud. The method includes generating an encrypted profile representing browser activity, sending the encrypted profile to a secure multiparty computation system, receiving a trust token from the secure multiparty computation system, based on a determination that the web browser is not engaged in online fraud, sending a request to redeem the trust token with the secure multiparty computation system, receiving an encrypted record of redemption from the secure multiparty computation system based on a determination that a web site associated with the web content is not blocked, and sending a request, containing the encrypted record of redemption, for third-party content, wherein the third-party content is associated with the web content.

Abstract: Addressable actuator and arrays thereof are described. Actuators may be dielectric elastomer actuators (DBAs). An addressable actuator may include a compliant substrate, with an optical receiver integrated with a first region of the compliant substrate and an actuator integrated with a second region of the compliant substrate, with the optical receiver coupled to the actuator. The optical receivers may comprise percolating networks of semiconductor materials, such as photoconductive channels of zinc oxide nanowires, which may be embedded in a compliant substate, or one or more compliant layers (which may be formed on a substrate). Compliant substrates or layers may include complaint materials such as an elastomer. An actuator array may comprise multiple of the actuators, with each actuator being independently optically addressable. A system may include light emitting devices optically coupled to respective optical receivers to control actuation of the actuators using light.

Abstract: A system and method may adjust the evaluation of input signals from an input device used by a game player, based on performance or motor acuity. A relationship or mapping between computer input device input and movement within a virtual environment may be adjusted based on the performance metric. An embodiment may measure or calculate a performance metric or motor acuity in a person playing a computer game by determining, for different target types, speed of the player and one of precision, accuracy and variability of the player; and determining motor acuity based on the relationship between speed of the player and the precision, accuracy or variability. The calculation may be using a statistical analysis; and may be by creating a best-fit line in a comparison of speed and variability; and transforming the best-fit line to a curve in a comparison of player speed and player precision.

Abstract: A fluid circulation assembly defining a vertical direction includes a drive shaft defining an axial direction, a radial direction, and a circumferential direction, a motor operable to rotate the drive shaft in a first direction and in a second direction opposite the first direction, and a drain pump assembly. The drain pump assembly includes a hub assembly mounted to the drive shaft and a plurality of rigid vanes, each of the plurality of rigid vanes being rotatably mounted to the hub assembly at a pivot point and extending to a distal end and being movable between an extended position when the motor is rotating in the first direction and a retracted position when the motor is rotating in the second direction.

Abstract: The present disclosure includes, among other things, CFTR modulators, pharmaceutical compositions, and methods of making and using the same.

Abstract: A wireless charging system includes a platform having a substantially horizontal upper surface configured to support a vehicle and an induction coil coupled to the platform. The induction coil is configured to receive electrical energy from an energy source and generate a magnetic field above the substantially horizontal upper surface, the magnetic field being positioned to wirelessly transfer the electrical energy to the vehicle while the vehicle is positioned atop the platform. A ramp is coupled to a side of the platform and extending away from the platform. An electrical cabinet is pivotally coupled to the platform and containing the energy source.

Abstract: A denormalised database structure and access methodology to allow efficient querying of permissions data and visualisation of permissions data.

Abstract: The present invention provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The invention also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.