Abstract: An oil-conditioning filter, for use with an internal combustion engine, includes a mechanically active filter element and a chemically active filter element. The chemically active filter element has a beneficial oil conditioning agent contained in a plurality of porous additive-dispensing modules. Each of the additive-dispensing modules includes a hollow housing having a plurality of holes formed therein, and a beneficial oil additive disposed within the housing. Optionally, each additive-dispensing module may also include a porous or semi-porous polymeric membrane covering the housing, to control the rate at which the additive material diffuses outwardly therefrom.

Abstract: Described are compounds and a method of inhibiting epidermal growth factor receptor tyrosine kinase by treating, with an effective inhibiting amount, a mammal, in need thereof, a compound of Formula II: where: one of A or E is nitrogen, with remaining atoms carbon; X=O, S, NH or NR7, such that R7=lower alkyl (1-4 carbon atoms), OH, NH2, lower alkoxy (1-4 carbon atoms) or lower monoalkylamino (1-4 carbon atoms). Other terms are described in the specification.

Abstract: A regenerable desiccant filter assembly, for use in a vehicle lamp housing, includes a hollow body defining a chamber therein, the hollow body having an inlet and an outlet formed therein to allow air to flow from an area outside said hollow body into and through the hollow body. A substrate, which is a nonwoven fiber mat, is housed within the hollow body; and a regenerable liquid desiccant composition is distributed on the substrate. Preferably, the fibers making up the substrate have hollow internal cavities formed therein, and extended openings formed in the sides thereof in communication with the internal cavities. Preferably, the desiccant composition is an alkali halide or an alkaline earth halide. Most preferably the desiccant composition is selected from the group consisting of lithium chloride, calcium chloride and magnesium chloride. In specific embodiments, the desiccant filter may be combined with a bulb shield or with a bulb socket member.

Abstract: Spandex having improved heat-set efficiency, obtained by incorporating certain quaternary amine additives into the spinning solution, is provided.

Abstract: An apparatus and method for detecting the presence of a signal component in an arbitrary signal, where the signal component has a desired frequency. The apparatus includes an error signal generator and a detector. The error signal generator has an input for receiving a reference signal having a reference frequency, a second input for receiving the arbitrary signal having the signal component and an output for generating a difference signal dependent upon a difference in frequency between the reference frequency and the desired frequency. The detector has an input for receiving the difference signal and an output for producing a detector signal when the magnitude of the difference signal is greater than a threshold magnitude. The detector signal indicates the presence of the signal component in the arbitrary signal.

Abstract: A fluid filter increases the useful life of the filtered fluid by removing contaminants therefrom, and may optionally provide for in-line delivery of additives to the filtered fluid. The filter may be an oil filter, a fuel filter, or other fluid filter. The fluid filter includes a casing which defines a hollow space therein, a mechanically active filter element within that space, and a chemically active filter element also retained within the hollow space proximate the mechanically active filter element. The chemically active filter element includes a nonwoven web made up of a plurality of fibers. Each fiber has a longitudinally extending internal cavity formed therein, and a corresponding longitudinally extending slot opening from that internal cavity to the outer surface of the fiber.

Abstract: An improved oil conditioning filter, for use with an internal combustion engine, includes a mechanically active filter element and a chemically active filter element containing a beneficial additive therein. The beneficial additive is provided to extend the useful life of lubricating oil in an internal combustion engine. The beneficial additive may include an antioxidant, an anti-wear agent, and/or a basic salt. In a preferred embodiment of the invention, the chemically active conditioning agent is provided in a plurality of particles disposed within the oil filter housing. The particles may be bonded together to form an integral porous filter element having spaces defined between the particles thereof. The particles are made either by a hot extrusion process or by a solvent process.

Abstract: An antiviral agent capable of disrupting the association of two viral proteins required for DNA replication in herpesviruses. The agents disrupt the association of UL8 and POL in HSV-1 or the association of equivalent homologues of these proteins in other herpesviruses (for example UL 102 and UL54 in HCMV). Suitable agents are peptides which mimic the C-terminal or C-proximal portion of UL8 (or its homologues) for example the peptide IELVFTGVLAGVWGEGGKFV. Peptidomimetic compounds of such peptides are also suitable anti-viral agents. An assay to test for agents capable of disrupting association of POL and UL8 (or homologues thereof) is also described.

Abstract: Described are compounds and a method of inhibiting epidermal growth factor receptor tyrosine kinase by treating, with an effective inhibiting amount, a mammal, in need thereof, a compound of Formula II: 1

Abstract: Described are compositions and a method of inhibiting epidermal growth factor receptor tyrosine kinase by treating, with an effective inhibiting amount, a mammal, in need thereof, a compound of Formula II: where: any two continguous positions in positions A-E taken together can be a single heteroatom selected from the group consisting of nitrogen, oxygen or sulfur, in which case the other two remaining atoms must be carbon; the remaining substituents are disclosed in the specification

Abstract: A method for treating patients having bladder dysfunction is described. The method involves the step of treating a patient with a renin-angiotensin system inhibitor. Preferably the inhibitor is an Angiotensin II antagonist, an ACE inhibitor, or a renin inhibitor. Compositions of a combination of an AT1 specific Angiotensin II antagonist and an Angiotensin II agonist are also described. The compositions are useful for treating bladder dysfunction.

Abstract: Novel 4-substituted amino pyrido [3,2-d]pyrimidine inhibitors of epidermal growth factor receptor family of tyrosine kinases are described, as well as pharmaceutical compositions of the same, which are useful in treating proliferative diseases such as cancer, synovial pannus invasion in arthritis, psoriasis, vascular restenosis and angiogenesis and additionally useful in the treatment of pancreatitis and kidney disease as well as a contraceptive agent.

Abstract: A Portable Automated Water Purifier and Method is disclosed. Also disclosed is a preferred purifier that accepts supply water from a common water spigot and purifies it via a reverse osmosis (or other preferred filtration) process. The purified water is dispensed into a vessel until such time as a non-intrusive level detector indicates that the vessel is fill. The preferred level detector is able to detect the amount of water in the vessel from outside of the vessel, and without the use of a weight scale. The device might detect when the vessel is removed from it's dispensing location, such that the purifier dispensing will be stopped. The preferred purifier includes guides to steady the vessel as it sits in the dispensing location. In another preferred embodiment, a means for filling a beverage preparing device, such as an automatic coffee maker, is included.

Abstract: Methods and compositions for treating patients having erectile dysfunction are described. The method involves the step of treating a patient with a combination of an AT.sub.1 specific Angiotensin II antagonist and Angiotensin II agonist. Preferably the AT.sub.1 specific Angiotensin II antagonist is an AT.sub.1 specific Angiotensin II antagonist. The composition is a pharmaceutical composition including an equivalent molecular ratio of an AT.sub.1 specific Angiotensin II antagonist and Angiotensin II agonist.

Abstract: A communications processor (30) includes a DMA controller (34) and a module associated with a broadcast communications protocol such as a CAN module (50), both connected to a common internal bus (36). The CAN module (50) includes a single comparator (56) for comparison of multiple identifier mask values with the identifier of a message transmitted on the CAN bus (25). The communications processor (30) also includes a random access memory (RAM) (40) which stores the multiple identifier mask values which the DMA controller (34) automatically transfers to the CAN module (50) without intervention by the CPU (32). In addition, the CAN module (50) provides a valid message interrupt to the CPU (32) only after the message has been validated and does not interrupt the CPU (32) when messages intended only for other nodes are encountered.

Abstract: A new treatment schedule for administration of N-?2-(dimethylamino)ethyl!acridine-4-carboxamide and other related carboxamide anticancer drugs in which the drug is administered in a divided-dose schedule comprising two or more administrations at frequent intervals, for example every hour. Schedules to produce cyclic peaks/troughs in plasma levels are mentioned. The compounds can be used for circumventing multidrug resistance in cancers and may, for example, be used in combination with other cytotoxic drugs, especially non-topo II inhibitors. Treatment of melanoma and advanced colon cancer is included.

Abstract: A method of controlling an oxygen generation device of the kind including a ceramic membrane through which an electrical current is passed whilst ambient air is supplied to one side of the membrane, the membrane allowing oxygen in the supplied air to diffuse therethrough by ionic transport when the membrane is at or above an operating temperature, at a rate dependant upon the electrical current, there being a plenum or the like to recover the oxygen at a second side of the membrane, the method comprising regulating the electrical current passing through the membrane by switching the electrical current on and off and varying the proportion of current-on time in a given time interval (t) in dependence upon a feedback signal.

Abstract: There is disclosed a combustion control circuit of a combustion apparatus with a driving signal generator, an exhaust fan controller and a gas valve controller, including: a combustion state detector for detecting the state of combustion occurring within a combustion chamber according to an output signal of a flame sensor installed in the combustion chamber, and for producing a signal corresponding to the state of combustion; a reference signal generator for producing a reference signal in response to each output signal of a temperature sensor and a flow sensor; a comparator for comparing the output signal of the combustion state detector with the output signal of the reference signal generator, and for outputting a signal corresponding to a difference therebetween; and an adder for adding the output signal of the comparator to the output signal of the driving signal-generator, and for respectively applying an output to each one of the exhaust fan controller and the gas valve controller.

Abstract: There is disclosed a combustion-state detecting circuit of a combustion apparatus installed in a combustion chamber, including: a flame detector that has a heat-emitting device for emitting heat on application of an alternating current signal, and produces a potential difference between the current applied to the heat-emitting device and flame-electric current produced by ignition occurring within the combustion chamber; a rectifier that changes the alternating current signal provided by the flame detector into a direct current signal; an inversion amplifier that inverts the direct current signal produced by the rectifier with respect to a reference signal and increases the magnitude of the inverted signal; and a flame discriminator that compares the output signal of the inversion amplifier with a flame discriminating reference signal to determine if ignition occurs.

Abstract: A line communication system for linking a plurality of telephone subscribers to a public telephone exchange, wherein the subscribers are each located within the same general area, and wherein each subscriber is fed from the same mains electricity sub-station with mains electricity is provided. The line communication system provides subscriber apparatus which includes a cordless telephone (CT) handset and a frequency convertor for each subscriber. The handset is hard-wired to the mains electricity supply conductors via the frequency convertor so that CT signals at UHF are down-converted to HF for transmission through the mains electricity conductors. A CT base station is connected to the public telephone exchange. The CT base station is connected to the mains electricity supply conductors via a further frequency convertor for HF line communication purposes.