Abstract: A 3D semiconductor memory device includes an electrode structure on a substrate, the electrode structure including gate electrodes stacked in a first direction perpendicular to a top surface of the substrate, a vertical semiconductor pattern penetrating the electrode structure and connected to the substrate, and a data storage pattern between the electrode structure and the vertical semiconductor pattern. The data storage pattern includes first, second and third insulating patterns sequentially stacked. Each of the first to third insulating patterns includes a horizontal portion extending in a second direction parallel to the top surface of the substrate. The horizontal portions of the first, second and third insulating patterns are sequentially stacked in the first direction. At least one of the horizontal portions of the first and third insulating patterns protrudes beyond a sidewall of the horizontal portion of the second insulating pattern in the second direction.

Abstract: The present disclosure provides a stopped cooling system including: a steam line connecting portion connected to a steam line so as to receive cooling water through the steam line connected to an outlet of a steam generator; a stopped cooling heat exchanger for receiving cooling water that enters the stopped cooling system through the steam line connecting portion, and discharging same through a passage of the heat exchanger; a stopped cooling pump activated to perform stopped cooling of the nuclear reactor upon normal stoppage of the nuclear reactor after primary cooling of the nuclear reactor cooling system or when an accident occurs, and for forming a circulating flow of cooling water that circulates between the steam generator and the stopped cooling heat exchanger; and a water supplying pipe connecting portion connected to the heat exchanger passage and a water supplying pipe, which is connected to the inlet of the steam generator, so as to supply the cooling water cooled in the stopped cooling heat exch

Abstract: The present invention relates to a pharmaceutical composition with enhanced stability, containing pemetrexed or a salt thereof, and a preparation method therefor. The present invention provides an injection preparation in liquid form containing pemetrexed, capable of ensuring sufficient stability during circulation and storage by selection of an optimum material and setting of an optimum concentration range in order to secure the stability of pemetrexed. The present invention can provide a pemetrexed preparation which is readily commercially prepared, can prevent microbial contamination occurring during lyophilization or reconstitution, and has enhanced convenience of administration and stability.

Abstract: The present invention discloses a passive cooling system of a containment building, to which a plate-type heat exchanger is applied. A passive cooling system of a containment building comprises: a containment building; a plate-type heat exchanger provided to at least one of the inside and the outside of the containment building and comprising channels respectively provided to the both sides of a plate so as to be arranged dividedly from each other such that the plate-type heat exchanger carries out mutual heat exchange between the internal atmosphere of the containment building and a heat exchange fluid while maintaining a pressure boundary; and a pipe connected to the plate-type heat exchanger by penetrating the containment building so as to form the path of the internal atmosphere of the containment building or the heat exchange fluid.

Abstract: A 3D semiconductor memory device includes an electrode structure on a substrate, the electrode structure including gate electrodes stacked in a first direction perpendicular to a top surface of the substrate, a vertical semiconductor pattern penetrating the electrode structure and connected to the substrate, and a data storage pattern between the electrode structure and the vertical semiconductor pattern. The data storage pattern includes first, second and third insulating patterns sequentially stacked. Each of the first to third insulating patterns includes a horizontal portion extending in a second direction parallel to the top surface of the substrate. The horizontal portions of the first, second and third insulating patterns are sequentially stacked in the first direction. At least one of the horizontal portions of the first and third insulating patterns protrudes beyond a sidewall of the horizontal portion of the second insulating pattern in the second direction.

Abstract: A vertical semiconductor device includes a substrate with a first and second region. A conductive pattern on the first region extends in a first direction. The first region includes a cell region, a first dummy region and a second dummy region. The conductive pattern extends in a first direction. A pad is disposed on the second region, the pad contacts a side of the conductive pattern. A plurality of first dummy structures extends through the conductive pattern on the first dummy region. A plurality of second dummy structures extend through the conductive pattern on the second dummy region, the second dummy structures disposed in a plurality of columns that extend in a second direction perpendicular to the first direction. Widths of upper surfaces of the second dummy structures are different in each column, and the widths of upper surfaces of the second dummy structures increase toward the second region.

Abstract: Disclosed herein is a sample collection apparatus. The sample collection apparatus includes a self-sampling pad and a cell fixing container, wherein the sample collection pad includes a filter unit, the structure and material of which are such that cells, viruses and DNAs contained in vaginal secretions can be efficiently absorbed and attached to the filter unit and can be efficiently detached from the filter unit in a cell preserving solution after the filter unit is removed and put into the cell preserving solution. Thus, the filter unit includes at least one adsorbent layer which is formed of a hydrophobic material having low fineness and high resilience.

Abstract: The present invention relates to a passive heat removal system which circulates cooling fluid to a steam generator via a main water supply line connected to the lower inlet of the steam generator, and a main steam pipe connected to the top outlet of the steam generator, to remove sensible heat of a nuclear reactor coolant system and residual heat of a core. The heat removal system comprises supplementary equipment for receiving surplus cooling fluid or for supplying supplementary cooling fluid in order to maintain the flow rate of the cooling fluid within a predetermined range. The supplementary equipment comprises: a supplementary tank, installed at a height between the lower inlet and the top outlet of the steam generator; a first connection pipe, connected to the main steam pipe and the supplementary tank; and a second connection pipe, connected to the supplementary tank and the main water supply pipe.

Abstract: Provided is a passive containment spray system including: a spray coolant storage unit that communicates with a containment accommodating a reactor vessel and maintains equilibrium of pressure between the spray coolant storage unit and the containment; a spray pipe that is installed within the containment in such a manner that when an accident occurs, a coolant supplied from the spray coolant storage unit is sprayed into the containment through the spray pipe due to an increase in pressure within the containment; and a connection pipe one end of which is inserted into the spray coolant storage unit in such a manner as to provide a flow path along which the coolant flows and the other end of which is connected to the spray pipe in such a manner that the coolant is passively supplied to the spray pipe through the connection pipe therein.

Abstract: The present invention discloses a nuclear reactor coolant pump that does not rely on an electric motor, but is operated by means of driving force generated inside a nuclear power plant, so a to be capable of maintaining the safety of the nuclear reactor when the nuclear reactor is operating normally and also in the event of an accident in the nuclear reactor. The nuclear reactor coolant pump comprises: a pump impeller rotatably installed in a first fluid passage of a nuclear reactor coolant system to circulate a first fluid inside the nuclear reactor coolant system; a drive unit receiving steam from a steam generator to generate driving force to rotate the pump impeller, and rotating about the same rotating shaft as the pump impeller to transfer the generated driving force to the pump impeller; and a steam supplying unit forming a passage between the steam generator and the drive unit to supply at least a portion of the steam released from the steam generator to the drive unit.

Abstract: Provided are a method of detecting chromosomal aneuploidy of a targeted fetal chromosome, and a computer-readable medium having recorded thereon a program to be applied to performing the method. According to the present disclosure, fetal chromosomal aneuploidy may be non-invasively and prenatally diagnosed with excellent sensitivity and specificity.

Abstract: The present disclosure provides a cooling system of an emergency cooling tank, which enables long-term cooling without refilling cooling water, in case of the change in a quantity of heat transferred to the emergency cooling tank according to a lapse of time upon an occurrence of an accident of a nuclear reactor, and a nuclear power plant having the same. The emergency cooling tank cooling system includes an emergency cooling tank, a heat exchanging device installed to be exposed to an outside of the emergency cooling tank to operate in air, and configured to externally emit such that the operation of the emergency cooling tank is continued even without refilling the cooling water, and an opening and closing unit installed at an upper portion of the emergency cooling tank to be located higher than a water level of the cooling water.

Abstract: The present invention provides passive safety equipment, comprising: a cooling part formed to cool a first fluid, which is emitted from a reactor coolant system or a steam generator, and a second fluid in a housing; and a circulation induction sprayer which is formed to spray the first fluid emitted from the reactor coolant system or the steam generator into the cooling part, has at least part thereof open to the inside of the housing such that the second fluid flows thereinto according to a drop in pressure caused by the spraying of the first fluid, and sprays the second fluid with the inflown first fluid.

Abstract: The present disclosure provides a stopped cooling system including: a steam line connecting portion connected to a steam line so as to receive cooling water through the steam line connected to an outlet of a steam generator; a stopped cooling heat exchanger for receiving cooling water that enters the stopped cooling system through the steam line connecting portion, and discharging same through a passage of the heat exchanger; a stopped cooling pump activated to perform stopped cooling of the nuclear reactor upon normal stoppage of the nuclear reactor after primary cooling of the nuclear reactor cooling system or when an accident occurs, and for forming a circulating flow of cooling water that circulates between the steam generator and the stopped cooling heat exchanger; and a water supplying pipe connecting portion connected to the heat exchanger passage and a water supplying pipe, which is connected to the inlet of the steam generator, so as to supply the cooling water cooled in the stopped cooling heat exch

Abstract: The present invention provides a facility for reducing radioactive material comprising: a cooling water storage unit installed inside a containment and formed to store cooling water; a boundary unit forming a boundary of radioactive material inside the containment and surrounding a reactor coolant system installed inside the containment to prevent a radioactive material from releasing from the reactor coolant system or a pipe connected with the reactor coolant system to the containment; a connecting pipe connected with an inner space of the boundary unit and the cooling water storage unit to guide a flow of a fluid caused by a pressure difference between the boundary unit and the cooling water storage unit from the boundary unit to the cooling water storage unit; and a sparging unit disposed to be submerged in the cooling water stored in the cooling water storage unit and connected with the connecting pipe to sparge the fluid that has passed through the connecting pipe and the radioactive material contained i

Abstract: The present invention relates to a cell collection pad for cervical disease screening and a collection kit including the same. The cell collection pad takes the form of a wearable pad and includes a filter unit collecting cervical cells and an absorption unit absorbing vaginal secretions having passed through the filter unit, thereby collecting cervical cells from the human body in an easy and stable manner.

Abstract: A cell smearing apparatus comprising: a mixed solution container accommodation unit accommodating a mixed solution container containing a mixed solution of cells and a preservation solution; a suction unit suctioning the mixed solution from the mixed solution container accommodated in the mixed solution container accommodation unit; a sensor unit sensing variation of the mixed solution suctioned by the suction unit; and a controller controlling a suctioning speed of the suction unit based on a value sensed by the sensor unit. The present invention allows cells to be examined to be smeared as a monolayer on a slide for microscopic examination.

Abstract: A method of manufacturing a vertical memory device includes forming a preliminary first mold structure on a substrate, which includes main and edge regions, and the first preliminary mold structure including alternating insulation and sacrificial layers, forming a first mask on the preliminary first mold structure to expose the preliminary first mold structure between a boundary of the substrate and a first target position, partially etching the insulation and sacrificial layers using the first mask to form a preliminary second mold structure, forming a second mask on the preliminary second mold structure to expose the preliminary second mold structure between the boundary of the substrate and a second target position different from the first target position, and partially etching the insulation layers and the sacrificial layers using the second mask.

Abstract: A vertical memory device includes a substrate having a cell array region and a connection region positioned on an exterior of the cell array region. Gate electrode layers are stacked on the cell array region and the connection region of the substrate, forming a stepped structure in the connection region. Channel structures are disposed in the cell array region, extending in a direction perpendicular to an upper surface of the substrate, while passing through the gate electrode layers. Dummy channel structures are disposed in the connection region, extending in the same direction as the channel structures, while passing through the gate electrode layers forming the stepped structure. First semiconductor patterns are disposed below the channel structures, and second semiconductor patterns are disposed below the dummy channel structures. The first and second semiconductor patterns include polycrystalline semiconductor materials.

Abstract: A cell smearing apparatus comprising: a mixed solution container accommodation unit accommodating a mixed solution container containing a mixed solution of cells and a preservation solution; a suction unit suctioning the mixed solution from the mixed solution container accommodated in the mixed solution container accommodation unit; a sensor unit sensing variation of the mixed solution suctioned by the suction unit; and a controller controlling a suctioning speed of the suction unit based on a value sensed by the sensor unit. The present invention allows cells to be examined to be smeared as a monolayer on a slide for microscopic examination.