Abstract: A computer system may include a server configured to provide access to a plurality of shared applications, and a client computing device. The client computing device may have a display associated therewith and cooperate with the server to run shared applications from among the plurality of shared applications, determine at least one group of the shared applications running on the client computing device having a relationship therebetween based upon a sequence in which the shared applications are activated, and display the shared applications from the at least one group on the display.

Abstract: A soil measurement system is provided, comprising a soil surveying device, a radio receiver, a plurality of subterranean antennas, and a processor. The soil surveying device comprises a wireless radio transmitter configured to emit a wireless signal at a predetermined bandwidth in a predetermined spectrum. The plurality of subterranean antennas are in an array electronically connected to the radio receiver and configured to be mounted in a subterranean environment at different depths in the subterranean environment. Each of the plurality of subterranean antennas is configured to receive the wireless signal at a respective point in time. The processor is configured to determine a relative time of flight of the received wireless signal between the plurality of antennas at the respective point in time, and estimate a soil permittivity based on the determined relative time of flight. The measurement system may be applied to materials other than soil, in some examples.

Abstract: A class of substituted triazolopiperazine compounds represented by formula (I), tautomers, enantiomers, diastereomers, racemates, metabolites, metabolic precursors, and pharmaceutically acceptable salts, esters, prodrugs or hydrate thereof, a preparation methods therefor, intermediates and a use thereof in the preparation of drugs for prevention and treatment of diseases associated with PARP including various ischemic diseases, neurodegenerative diseases and cancers.

Abstract: The invention relates to a new method of preparing oligomannuronic diacids, important bioactives. The method utilizes oligomannuronic acids as starting materials and the target substances are obtained by acid degradation and active hypobromous acid oxidation steps. The method of preparing oligomannuronic diacids according to the invention employs moderate reaction conditions, has few side reactions, does not need further purification, achieves a yield of more than 90%, or even more than 95%, and is suitable for production with an on-line continuous reactor device, with reaction processes easy to implement automatic control.

Abstract: An o-aminoheteroaryl alkynyl-containing compound has a structure represented by formula (I), and the compound of formula (I) has advantages of a high FGFR and RET double target inhibitory activity and a relatively low KDR activity, and the compound of formula (I) exhibits a strong inhibitory activity in a human lung cancer cell line NCI-H1581 and a gastric cancer cell line SNU16 as well as an RET-dependent sensitive cell line BaF3-CCDC6-Ret and a mutant thereof. Pharmacokinetic data shows that the o-aminoheteroaryl alkynyl-containing compound has druggability, and exhibits significant relevant inhibition of the growth of related tumors in a long-term animal model of drug efficacy and results in favorable animal condition at effective doses.

Abstract: The present invention provides an indazole compound as a FGFR kinase inhibitor, preparation and use thereof. Specifically, the present invention provides a compound represented by formula (I), wherein the definitions of each group are described in the specification. The compound of the present invention has good FGFR kinase-inhibiting activity, and can be used in preparing a series of medicines for treating FGFR kinase activity related diseases.

Abstract: A new compound having an FGFR inhibitory activity and preparation and application thereof are provided. In particular, the compound according to the invention has a structure as shown in formula I, in which each group and substituent are as defined in the description. Also, a preparation method for the compound and a use thereof in preparation of a drug for treating and/or preventing a tumor-related disease and/or an FGFR-related disease are provided.

Abstract: The present invention relates to a method for degrading a polysaccharide in the field of food, medicine or chemical industry. In particular, a molecular chain of the polysaccharide is broken by ozone into polysaccharides with smaller molecular weights, oligoses and/or oligosaccharides. The polysaccharides include linear or branched glycans extracted from plants, traditional Chinese medicinal materials, animals, fungi, or microorganisms and sulfated polysaccharides or esterified polysaccharides formed by sulfation or esterification thereof. As an oxidizing agent in the reaction, the ozone can be used alone or can be used under the catalysis of a base, a metal ion, hydrogen peroxide, UV light, or activated carbon to accelerate the reaction.

Abstract: This application provides a service deployment method and apparatus. The method includes: determining a first component node that needs to be deployed currently in a to-be-deployed service; obtaining, from a physical cluster, a physical node set that meets a computing resource requirement of the first component node; and obtaining, from the physical node set according to a current available network resource of each physical node in the physical node set, a physical node to which the first component node is mapped. According to the technical solution provided in this application, in a node mapping process of service deployment, that is, in a process of determining a physical node to which a component node is mapped, a computing resource and a network resource are comprehensively considered.

Abstract: The present disclosure relates to a Pyrimido[5,4-b]indolizine or pyrimido[5,4-b]pyrrolizine compound, preparation method thereof and use thereof. The compounds of the present invention have good inhibitory activities against BTK at the molecular and cellular levels. Importantly, the compounds of the present invention have low activity against Ramos cells of normal human B lymphoma cells, and have high activity against BTK-sensitive human diffuse large B lymphoma TMD8 cells, indicating that these type of compounds with novel structural are highly selective, off-target phenomenon and corresponding side effects are low. Thus it is a selective inhibitor of BTK with development potential.

Abstract: Disclosed is a method for processing downlink signalling of an SDN virtualization platform based on OpenFlow. The method comprises: after the preprocessing of downlink signalling is executed, further executing same, so as to judge whether more Match items also exist in a Match item list; if it is judged that more Match items also exist, acquiring an item from the Match item list; if it is judged that there are no more Match items, ending the processing; after completing the step of acquiring an item from the Match item list if it is judged that more Match items also exist, further judging whether more Action items also exist; if there are no more Action items, combining a new Action item list with the Match items to generate downlink signalling, and issuing same to a virtual network switch; and returning to the step to continue judging whether more Match items also exist; and if more Action items also exist, acquiring the next Action item.

Abstract: The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.

Abstract: The invention describes an aryl-2,2?-tandem bisthiazole compound and a preparation method and the use thereof. In particular, disclosed in the present invention are an aryl-2,2?-tandem bisthiazole compound with the structure as shown in general formula I and the preparation method thereof and use thereof as a histone deacetylase inhibitor in the preparation of antitumor drugs.

Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein: Also provided are methods of making the compounds of Formula (I) and their methods of use.

Abstract: Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use therefor.

Abstract: A method for generating an augmented reality module by an apparatus is described. Processing circuitry of the apparatus obtains preset third party software development interface information, the third party software development interface information being uniformly encapsulated with an AR core engine and an AR rendering engine, and a system parameter and pose information that are associated with the AR core engine being passed into the AR rendering engine. The processing circuitry generates, according to the third party software development interface information and a document configured corresponding to the third party software development interface information, an AR module of a mobile client, the correspondingly configured document comprising interface use information of the AR core engine and the AR rendering engine.

Abstract: Provided in the present invention are a compound having the effects of preventing and treating diseases related to IDH mutation, and a preparation method and use thereof.

Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein: Also provided are methods of making the compounds of Formula (I) and their methods of use.

Abstract: Approaches, techniques, and mechanisms are disclosed for the collection, distribution, and/or reporting of media content. According to an embodiment, media content items from one or more content providers are ingested into a content distribution system implemented by one or more server computer devices. These items of media content may comprise a variety of constituent elements, such as one or more video data units, one or more audio data units, descriptive metadata, subtitle units, thumbnails, or other information, which may be ingested all at once, or separately over time. Items may be processed using various workflows to refine content item components and/or generate new content items. Various publishing rules may be utilized to determine when the system is ready to publish a content item and distribute the item to client devices. Clients may request content items from various published listings, or search for content items by metadata and/or subtitles.

Abstract: A catalyst for producing light aromatics with heavy aromatics, a method for preparing the catalyst, and a use thereof are disclosed. The catalyst comprises a carrier, component (1), and component (2), wherein component (1) comprises one metal element or more metal elements selected from a group consisting of Pt, Pd, Ir, and Rh, and component (2) comprises one metal element or more metal elements selected from a group consisting of IA group, IIA group, IIIA group, IVA group, IB group, IIB group, IIIB group, IVB group, VB group, VIB group, VIIB group, La group, and VIII group other than Pt, Pd, Ir, and Rh. The catalyst can be used for producing light aromatics with heavy aromatics, whereby heavy aromatics hydrogenation selectivity and light aromatics yield can be improved.