Abstract: This application provides a service deployment method and apparatus. The method includes: determining a first component node that needs to be deployed currently in a to-be-deployed service; obtaining, from a physical cluster, a physical node set that meets a computing resource requirement of the first component node; and obtaining, from the physical node set according to a current available network resource of each physical node in the physical node set, a physical node to which the first component node is mapped. According to the technical solution provided in this application, in a node mapping process of service deployment, that is, in a process of determining a physical node to which a component node is mapped, a computing resource and a network resource are comprehensively considered.

Abstract: The present disclosure relates to a Pyrimido[5,4-b]indolizine or pyrimido[5,4-b]pyrrolizine compound, preparation method thereof and use thereof. The compounds of the present invention have good inhibitory activities against BTK at the molecular and cellular levels. Importantly, the compounds of the present invention have low activity against Ramos cells of normal human B lymphoma cells, and have high activity against BTK-sensitive human diffuse large B lymphoma TMD8 cells, indicating that these type of compounds with novel structural are highly selective, off-target phenomenon and corresponding side effects are low. Thus it is a selective inhibitor of BTK with development potential.

Abstract: Disclosed is a method for processing downlink signalling of an SDN virtualization platform based on OpenFlow. The method comprises: after the preprocessing of downlink signalling is executed, further executing same, so as to judge whether more Match items also exist in a Match item list; if it is judged that more Match items also exist, acquiring an item from the Match item list; if it is judged that there are no more Match items, ending the processing; after completing the step of acquiring an item from the Match item list if it is judged that more Match items also exist, further judging whether more Action items also exist; if there are no more Action items, combining a new Action item list with the Match items to generate downlink signalling, and issuing same to a virtual network switch; and returning to the step to continue judging whether more Match items also exist; and if more Action items also exist, acquiring the next Action item.

Abstract: The invention describes an aryl-2,2?-tandem bisthiazole compound and a preparation method and the use thereof. In particular, disclosed in the present invention are an aryl-2,2?-tandem bisthiazole compound with the structure as shown in general formula I and the preparation method thereof and use thereof as a histone deacetylase inhibitor in the preparation of antitumor drugs.

Abstract: The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.

Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein: Also provided are methods of making the compounds of Formula (I) and their methods of use.

Abstract: Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use therefor.

Abstract: A method for generating an augmented reality module by an apparatus is described. Processing circuitry of the apparatus obtains preset third party software development interface information, the third party software development interface information being uniformly encapsulated with an AR core engine and an AR rendering engine, and a system parameter and pose information that are associated with the AR core engine being passed into the AR rendering engine. The processing circuitry generates, according to the third party software development interface information and a document configured corresponding to the third party software development interface information, an AR module of a mobile client, the correspondingly configured document comprising interface use information of the AR core engine and the AR rendering engine.

Abstract: A manufacture equipment for a large-area perovskite film, includes a vacuum chamber provided with a substrate heater therein for accommodating a substrate; a first evaporation case and a second evaporation case are disposed under the substrate heater in the vacuum chamber, the first evaporation case is embedded above the second evaporation case, a damper is disposed between the first evaporation case and the substrate heater; a first heater is disposed on the bottom of the first evaporation case, which is connected with a first carrier-gas pipe communicating with an external carrier-gas source; a second heater is disposed on the bottom of the second evaporation case, the second evaporation case is connected with a second carrier-gas pipe communicating with an external carrier-gas source. With the equipment, reaction species can be sprayed onto a substrate with carrier-gases and react to form perovskite film, which improves uniformity of the perovskite film.

Abstract: Provided in the present invention are a compound having the effects of preventing and treating diseases related to IDH mutation, and a preparation method and use thereof.

Abstract: Approaches, techniques, and mechanisms are disclosed for the collection, distribution, and/or reporting of media content. According to an embodiment, media content items from one or more content providers are ingested into a content distribution system implemented by one or more server computer devices. These items of media content may comprise a variety of constituent elements, such as one or more video data units, one or more audio data units, descriptive metadata, subtitle units, thumbnails, or other information, which may be ingested all at once, or separately over time. Items may be processed using various workflows to refine content item components and/or generate new content items. Various publishing rules may be utilized to determine when the system is ready to publish a content item and distribute the item to client devices. Clients may request content items from various published listings, or search for content items by metadata and/or subtitles.

Abstract: The disclosure provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein: Also provided are methods of making the compounds of Formula (I) and their methods of use.

Abstract: A catalyst for producing light aromatics with heavy aromatics, a method for preparing the catalyst, and a use thereof are disclosed. The catalyst comprises a carrier, component (1), and component (2), wherein component (1) comprises one metal element or more metal elements selected from a group consisting of Pt, Pd, Ir, and Rh, and component (2) comprises one metal element or more metal elements selected from a group consisting of IA group, IIA group, IIIA group, IVA group, IB group, IIB group, IIIB group, IVB group, VB group, VIB group, VIIB group, La group, and VIII group other than Pt, Pd, Ir, and Rh. The catalyst can be used for producing light aromatics with heavy aromatics, whereby heavy aromatics hydrogenation selectivity and light aromatics yield can be improved.

Abstract: A method of cleaning calibration and other substrates that improves the correlation of measurements from calibration and product substrates and increases the useful life of the calibration substrates is herein disclosed. By exposing a calibration substrate to ultraviolet light, a reaction is triggered that results in the cleaning of the contaminants from the calibration substrate. For instance, monatomic oxygen is introduced to contaminants on the surface of a calibration substrate to remove the contaminants without inducing modifications in the substrate itself. Through the cleaning process, the temperature of the calibration substrate may be controlled to limit adverse effects caused by the overheating of the calibration substrate.

Abstract: Wax esters (WE) and triacylglycerols (TAG) can be accumulated in large amounts in plant cells. The present invention relates to insect pheromone precursors which are produced as components of WE or TAG in plants. Further the invention concerns means and methods for the production of plant cells producing WE and/or TAG containing insect pheromone precursors in form of either a fatty acid or a fatty alcohol. Said method uses plants where wax esters are modified by desaturase, fatty acyl reductase and wax ester synthase or the triacylglycerol is modified by a desaturase. Finally the insect pheromone precursors can be extracted and used in the manufacturing of insect pheromones from WE and TAG.

Abstract: The present invention relates to a class of substituted triazolopiperazine compounds, tautomers, enantiomers, diastereomers, racemates, metabolites, metabolic precursors, and pharmaceutically acceptable salts, esters, prodrugs or hydrate thereof, a preparation methods therefor, intermediates and a use thereof in the preparation of drugs for prevention and treatment of diseases associated with PARP including various ischemic diseases, neurodegenerative diseases and cancers.

Abstract: Provided are a substituted quinolone derivative as shown by formula (I), or a pharmaceutically acceptable salt and a prodrug molecule thereof, and a pharmaceutical composition thereof, as well as the use of same in preparing drugs for the prevention and treatment of a tumor. The quinolone derivative, salt, prodrug molecule, and pharmaceutical composition thereof can be used as a protein kinase inhibitor, which is effective in inhibiting the activity of AXL protein kinase, and is capable of inhibiting the proliferation, migration and invasion of various tumor cells; and can be used in the preparation of anti-tumor drugs, especially drugs for treating hyperproliferative diseases such as a tumor in human beings and other mammals.

Abstract: Disclosed are a 2-aminopyrimidine compound and pharmaceutical composition and use thereof. The structure of the 2-aminopyrimidine compound is as represented by formula I, in the formula, R1, R2, R3, R4, R5, X, Y, Z, W, (i) being as defined in the specification and the claims. Such compounds effectively inhibit the growth of a variety of tumor cells and have inhibitory effects on EGFR and IGF1R protease, and can be used for preparing antineoplastic drugs and overcome the tolerance induced by the existing drugs such as gefitinib, erlotinib and the like. The compound has selectivity for tumors, in particular the wild-type non-small cell lung cancer and have good pharmacokinetic characteristics.

Abstract: A polygulonic acid sulfate or pharmaceutically acceptable salt thereof, preparation method therefor and use thereof in the preparation of tumor growth and/or metastasis inhibitors are disclosed. The polygulonic acid sulfate or pharmaceutically acceptable salt thereof of the present invention can be used in the preparation of any one or more of tumor growth inhibitors, tumor metastasis inhibitors, angiogenesis inhibitors, heparanase inhibitors, C-Met enzyme inhibitors, microtubule polymerization inhibitors, actin-depolymerizing factor activity inhibitors and actin-aggregation inhibitors.

Abstract: This invention provides a class of five-member-heterocycle fused pyridine compounds as shown below in Formula (X), pharmaceutically acceptable salts or pharmaceutically acceptable solvates thereof, a method of producing the same, pharmaceutical compositions containing the compound, and use of the compounds in preparing medicament for preventing and/or treating diseases and tumors associated with abnormal protein tyrosine kinase.