Patents by Inventor Jian Ding

Jian Ding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolo[2,1-][1,2,4]triazine compound, and preparation method and application thereof
    Patent number: 9447101
    Abstract: The present invention relates to a pyrrolo[2,1-f][1,2,4]triazine compound, an isomer thereof or a pharmaceutically acceptable salt, ester or hydrate thereof, and a preparation method and application thereof. The pyrrolo[2,1-f][1,2,4]triazine compound has a structure expressed in general formula (I). The pyrrolo[2,1-f][1,2,4]triazine compound expressed in general formula (I) can inhibit a phosphatidylinositol-3 kinase (PI3K) signal pathway, thereby being used to prepare medicine for treating phosphatidylinositol-3 kinase related diseases such as cancer.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: September 20, 2016
    Assignees: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai Haihe Pharmaceutical Co., Ltd.
    Inventors: Chunhao Yang, Linghua Meng, Yanhong Chen, Xiang Wang, Cun Tan, Jiapeng Li, Jian Ding, Yi Chen
  • CERTAIN PROTEIN KINASE INHIBITORS
    Publication number: 20160145244
    Abstract: Provided are certain ALK inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Application
    Filed: November 19, 2015
    Publication date: May 26, 2016
    Applicant: FOCHON PHARMA, INC.
    Inventors: Weibo Wang, Meiyu Geng, Jian Ding, Xingdong Zhao, Jing Ai, Huajie Zhang, Xia Peng
  • FIVE-MEMBER-HETEROCYCLE FUSED PYRIDINE COMPOUNDS, METHOD OF PRODUCING THE SAME, AND USE THEREOF
    Publication number: 20160137640
    Abstract: This invention provides a class of five-member-heterocycle fused pyridine compounds as shown below in Formula (X), pharmaceutically acceptable salts or pharmaceutically acceptable solvates thereof, a method of producing the same, pharmaceutical compositions containing the compound, and use of the compounds in preparing medicament for preventing and/or treating diseases and tumours associated with abnormal protein tyrosine kinase.
    Type: Application
    Filed: June 18, 2014
    Publication date: May 19, 2016
    Inventors: Jingkang Shen, Meiyu Geng, Jian Ding, Bing Xiong, Jing Al, Yuchi Ma, Xin Wang, Xia Peng, Yuelei Chen, Danqi Chen, Tao Meng, Lanping Ma, Yinchun Ji
  • Method, apparatus and terminal for detecting image stability
    Patent number: 9317770
    Abstract: An apparatus and terminal perform a method for detecting image stability in image processing. The method includes: acquiring N consecutive image frames, wherein N is an integer equal to 2 or larger; performing in each of the N consecutive image frames, the following: detecting corner points in the image frame, dividing the image frame into multiple areas, and recording distribution of the corner points in each of the multiple areas of the image frame in order to obtain a description vector of the image frame; calculating a number of areas according to the description vector of the image frame over the N consecutive image frames, wherein an existing state of the corner points has changed; determining whether the N consecutive image frames are stable, based on the number of areas which the existing state of the corner points has changed over the N consecutive image frames.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: April 19, 2016
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) CO., LTD.
    Inventors: Jian Ding, Xiao Liu, Hailong Liu, Bo Chen
  • CALIBRATION OF SEMICONDUCTOR METROLOGY SYSTEMS
    Publication number: 20160101445
    Abstract: A method of cleaning calibration and other substrates that improves the correlation of measurements from calibration and product substrates and increases the useful life of the calibration substrates is herein disclosed. By exposing a calibration substrate to ultraviolet light, a reaction is triggered that results in the cleaning of the contaminants from the calibration substrate. For instance, monatomic oxygen is introduced to contaminants on the surface of a calibration substrate to remove the contaminants without inducing modifications in the substrate itself. Through the cleaning process, the temperature of the calibration substrate may be controlled to limit adverse effects caused by the overheating of the calibration substrate.
    Type: Application
    Filed: October 13, 2015
    Publication date: April 14, 2016
    Applicant: Rudolph Technologies, Inc.
    Inventors: Jian Ding, Priya Mukundhan, James Kane, Steven Peterson, Fei Shen
  • CERTAIN PROTEIN KINASE INHIBITORS
    Publication number: 20160046638
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly novel pyrimidine derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Application
    Filed: October 29, 2015
    Publication date: February 18, 2016
    Inventors: Weibo WANG, Meiyu GENG, Jian DING, Xingdong ZHAO, Jing AI, Qiang TIAN, Xia PENG, Weipeng ZHANG, Hongbin LIU, Haohan TAN, Ling CHEN
  • Substituted [1,2,4]triazolo[4,3-a]pyrazines as PARP-1 inhibitors
    Patent number: 9255106
    Abstract: Provided is a piperazinotriazole compound represented by general formula I or a pharmaceutically acceptable salt, stereoisomer, tautomer or hydrate thereof. Also provided are a pharmaceutical composition comprising the compound, a method for preparing the compound and a method of use thereof as a high-selectivity poly(adenosine diphosphate-ribose)polymerase-1 (PARP-1) inhibitor in the preparation of drugs for the prevention and/or treatment of PARP-related diseases.
    Type: Grant
    Filed: July 24, 2013
    Date of Patent: February 9, 2016
    Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Ao Zhang, Zehong Miao, Na Ye, Xiajuan Huan, Zilan Song, Chuanhuizi Chen, Yi Chen, Jian Ding
  • Complement Factor B inhibitors and uses there of
    Publication number: 20160024079
    Abstract: The present invention provides a compound of formula (I): wherein X is N or CH, Y is NH, O or S, methods for manufacturing these compounds, and their uses as Factor B inhibitors for the treatment of conditions and diseases associated with complement alternative pathway activation such as age-related macular degeneration, diabetic retinopathy and related ophthalmic diseases. The present invention further provides pharmaceutical compositions and combinations of pharmacologically active agents.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 28, 2016
    Applicant: NOVARTIS AG
    Inventors: Christopher Michael ADAMS, Charles BABU, Michael Paul CAPPARELLI, Jian DING, Takeru EHARA, Keith JENDZA, Nan JI, Rajeshri Ganesh KARKI, Toshio KAWANAMI, Liang XUE, Nello MAINOLFI, James J. POWERS, Michael H. SERRANO-WU, Chun ZHANG
  • Thiazole compounds, methods for preparation and use thereof
    Patent number: 9216962
    Abstract: The present invention relates to thiazole compounds of formula I, the method for preparation and use thereof. More specifically, the present invention relates to novel derivatives of natural product largazole, the method for preparing them and their uses for treatments against tumor and multiple sclerosis as inhibitors of histone deacetylase.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: December 22, 2015
    Assignee: Shanghai Puyi Chemical Co., Ltd.
    Inventors: Fajun Nan, Fei Chen, Yangming Zhang, Jia Li, Yubo Zhou, Mingbo Su, Jian Ding, Linghua Meng, Xin Xie, Shixian Wang
  • Certain protein kinase inhibitors
    Patent number: 9206166
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly novel pyrimidine derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: December 8, 2015
    Assignees: Shanghai Institute of Materia Medica Academy of Sciences, Shanghai Fochon Pharmaceutical Co., LTD
    Inventors: Weibo Wang, Meiyu Geng, Jian Ding, Xingdong Zhao, Jing Ai, Qiang Tian, Xia Peng, Weipeng Zhang, Hongbin Liu, Haohan Tan, Ling Chen
  • Extracting Information from Chain-Store Websites
    Publication number: 20150287047
    Abstract: Provided is a process of extracting structured chain-store data from chain-store websites, the process including: identifying, via a processor, a store-locator webpage from a store website; querying the store-locator webpage for store locations in a geographic area; detecting a repeating pattern in a document object model (DOM) of a responsive webpage returned by the store website, the repeating pattern containing location information for stores in the geographic area; extracting, from the repeating pattern, location information for the stores in the geographic area; and storing the location information in a business listing repository.
    Type: Application
    Filed: June 19, 2013
    Publication date: October 8, 2015
    Inventors: Jifeng Situ, Yihua Wu, Kun Fang, Hui Xu, Erik Arjan Hendriks, Changxun Wu, Neha Sugandh, Jianning Ding
  • Complement pathway modulators and uses thereof
    Publication number: 20150250767
    Abstract: The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: May 19, 2015
    Publication date: September 10, 2015
    Applicant: NOVARTIS AG
    Inventors: Christopher Michael ADAMS, Charles BABU, Michael Paul CAPPARELLI, Jian DING, Takeru EHARA, Keith JENDZA, Nan JI, Rajeshri Ganesh KARKI, Toshio KAWANAMI, Liang XUE, Nello MAINOLFI, James J. POWERS, Michael H. SERRANO-WU, Chun ZHANG
  • Camptothecin compound containing stable 7-membered lactone ring, preparation method and use
    Patent number: 9115150
    Abstract: Provided are a camptothecin compound containing 7-membered lactone ring, as shown in general formula I, and pharmaceutically acceptable salt thereof, as well as the preparation method and use thereof. In general formula I, R1 is H, a C1˜C3 alkyl, acetyl or propionyl; R2 is H, a C1˜C6 alkyl, a C3˜C6 cycloalkyl, piperidyl; or a C1˜C6 alkyl substituted by an amino; R3 is H, a C1˜C3 alkyl, or a C1˜C6 alkyl substituted by an amino; R4 is H, a hydroxyl, or a C1˜C6 alkoxy; R5 is H, or a C1˜C6 alkoxyl; or R4 and R5 are linked to each other to form —OCH2O— or —OCH2CH2O—. The compound has good anti-tumor activity, and can be clinically used via oral administration, intravenous injection, and intramuscular injection, among others.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: August 25, 2015
    Assignees: EAST CHINA NORMAL UNIVERSITY, SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, NANJING LUYESIKE PHARMACEUTICAL CO., LTD.
    Inventors: Wei Lv, Shanbao Yu, Yu Luo, Yi Chen, Jian Ding
  • Method and system for automatically capturing an object using a mobile terminal
    Patent number: 9113002
    Abstract: A method for identifying relevant information of an object using a mobile terminal that has a built-in camera, a processor, and memory for storing programs to be executed by the processor is provided. The method includes automatically generating a plurality of image frames while the built-in camera pointing at the object; automatically transmitting one or more of the plurality of image frames to a remote server, wherein different transmitted image frames satisfy distinct predefined conditions; receiving information from the server when at least one of the transmitted image frames matches an image stored at the server, wherein the image corresponds to the object and is associated with information relevant to the object; and displaying the information relevant to the object at the mobile terminal.
    Type: Grant
    Filed: April 28, 2013
    Date of Patent: August 18, 2015
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Xiaolong Zhang, Jian Ding, Xiao Liu, Pinlin Chen, Hailong Liu, Junbin Kuang
  • PIPERAZINOTRIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN DRUG PREPARATION
    Publication number: 20150166544
    Abstract: Provided is a piperazinotriazole compound represented by general formula I or an isomer, a pharmaceutically acceptable salt, ester, prodrug or hydrate thereof. Also provided are a method for preparing the compound, a drug composition containing the compound, and a use thereof as a high-selectivity poly(ADP-ribose)polymerase-1 (PARP 1) inhibitor in the preparation of drugs for the prevention and/or treatment of PARP-related diseases.
    Type: Application
    Filed: July 24, 2013
    Publication date: June 18, 2015
    Inventors: Ao Zhang, Zehong Miao, Na Ye, Xiajuan Huan, Zilan Song, Chuanhuizi Chen, Yi Chen, Jian Ding
  • Complement pathway modulators and uses thereof
    Patent number: 9056874
    Abstract: The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: June 16, 2015
    Assignee: NOVARTIS AG
    Inventors: Christopher Michael Adams, Charles Babu, Michael Paul Capparelli, Jian Ding, Takeru Ehara, Keith Jendza, Nan Ji, Rajeshri Ganesh Karki, Toshio Kawanami, Liang Xue, Nello Mainolfi, James J. Powers, Michael H. Serrano-Wu, Chun Zhang
  • PYRROLO[2,1-F][1,2,4]TRIAZINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF
    Publication number: 20150141644
    Abstract: The present invention relates to a pyrrolo[2,1-f][1,2,4]triazine compound, an isomer thereof or a pharmaceutically acceptable salt, ester or hydrate thereof, and a preparation method and application thereof. The pyrrolo[2,1-f][1,2,4]triazine compound has a structure expressed in general formula (I). The pyrrolo[2,1-f][1,2,4]triazine compound expressed in general formula (I) can inhibit a phosphatidylinositol-3 kinase (PI3K) signal pathway, thereby being used to prepare medicine for treating phosphatidylinositol-3 kinase related diseases such as cancer.
    Type: Application
    Filed: April 23, 2013
    Publication date: May 21, 2015
    Applicants: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai Haihe Pharmaceutical Co., Ltd.
    Inventors: Chunhao Yang, Linghua Meng, Yanhong Chen, Xiang Wang, Cun Tan, Jiapeng Li, Jian Ding, Yi Chen
  • Security configuration verification device and method and network system employing the same
    Patent number: 8978134
    Abstract: The invention discloses a security configuration verification device for performing a security configuration verification on a network device, which comprises: one or more preconfigured scanning policies; a scanning policy generator, which selects a scanning policy from the one or more preconfigured scanning policies to generate a new scanning policy corresponding to the network device; and a scanner, which performs the security scanning on the network device with the generated new scanning policy and thereby performs the security configuration verification. The invention also discloses a corresponding security configuration verification method and a network system employing the verification device.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: March 10, 2015
    Assignee: NSFOCUS Information Technology Co., Ltd.
    Inventors: Baichuan Nie, Jianpeng Sun, Jian Ding, Dong Xu, Zhen Zhou
  • 2-ARYLBENZOFURAN-7-FORMAMIDE COMPOUNDS, PREPARATION METHOD AND USE THEREOF
    Publication number: 20150018542
    Abstract: Provided in the present invention are a 2-arylbenzofuran-7-formamide compound as shown in general formula I or a pharmacologically or physiologically acceptable salt thereof, a preparation method thereof and use thereof in preparing anti-tumour drugs, wherein R1 and R2 are each independently hydrogen, straight or branched chained C1-C4 alkyl, C3-C4 cycloalkyl or saturated 5- or 6-membered heterocyclyl containing oxygen or nitrogen; or R1 and R2 together with N form an unsubstituted or substituted saturated 5- or 6-membered heterocyclyl containing at least one heteroatom, wherein the heteroatom is O, N and S, the substituent is a methyl on N; R3 is a hydrogen atom or a chlorine atom; R4 is a hydrogen atom or a fluorine atom; X is CH, CF or N; and Y is CH, CF or N.
    Type: Application
    Filed: January 14, 2013
    Publication date: January 15, 2015
    Inventors: Chunhao Yang, Zehong Miao, Jian Ding, Meng Wang, Jinxue He, Cun Tan, Yi Chen
  • Hand-held massaging device
    Patent number: D740433
    Type: Grant
    Filed: July 20, 2013
    Date of Patent: October 6, 2015
    Inventors: Megan Zhu, Jian Ding