Abstract: The invention relates to the compounds of formula I, formula II and formula III or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II and formula III, and methods for treating or preventing Parkinson's disease may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment or management of Parkinson's disease such as Parkinson's disease, scleroderma, restless leg syndrome, hypertension and gestational hypertension.

Abstract: A device receives application information associated with a monolithic application, and generates a recommendation based on utilizing an artificial intelligence technique. The recommendation relates to a service to be generated, a service category for the service, and a deployment model for the service. The artificial intelligence technique generates the recommendation based on the application information. The device automatically generates code for the service based on the service category and the application information, receives a request to deploy the generated code for the service via the deployment model, and deploys the generated code, based on the request, to provide the service via the deployment model.

Abstract: Various additional and alternative aspects are described herein. In some aspects, the present disclosure provides a wireless device. The wireless device includes a first radio configured to communicate with a first data network. The wireless device includes a second radio configured to communicate with a second data network. The wireless device includes a thermal sensor array configured to measure a set of one or more thermal parameters associated with the wireless device. The wireless device includes a controller configured to allocate communication of data traffic between the first radio and the second radio based on the set of one or more thermal parameters.

Abstract: A video surveillance system having a plurality of aerial camera devices such as cameras on drones operable from a plurality of docking stations. Each station having a dock for receiving, charging, and controlling the aerial camera devices.

Abstract: Systems and methods for improving operational flexibility of a display pipeline coupled to a display panel that facilitates display of an image by controlling luminance of a display pixel based on display image data. The display pipeline includes a format convert block that receives source image data that indicates target luminance of the display pixel using a source format; determines a color scaling factor associated with a color component in the source image data based on the source format; and generates internal image data that indicates target luminance of the display pixel using an internal format based on application of the color scaling factor to the source image data. Additionally, the display pipeline includes an image data processing block coupled to the format convert block, which processes the internal image data before the display image data is generated to facilitate improving perceived image quality when the image is displayed.

Abstract: The present disclosure generally relates to context-based endpoint detection in user speech input. A method for identifying an endpoint of a spoken request by a user may include receiving user input of natural language speech including one or more words; identifying at least one context associated with the user input; generating a probability, based on the at least one context associated with the user input, that a location in the user input is an endpoint; determining whether the probability is greater than a threshold; and in accordance with a determination that the probability is greater than the threshold, identifying the location in the user input as the endpoint.

Abstract: Various embodiments provide an optimized image filter. The optimized image and video obtains an input image and selects a target pixel for modification. Difference values are then determined between the selected target pixel and each reference pixel of a search area. Subsequently, a weighting function is used to determine weight values for each of the reference pixels of the search area based on their respective difference value. The selected target pixel is then modified by the optimized image filter using the determined weight values. A new target pixel in an apply patch is then selected for modification. The new target pixel is modified using the previously determined weight values reassigned to a new set of reference pixels. The previously determined weight values are reassigned to the new set of reference pixels based on each of the new set of reference pixels' position relative to the new target pixel.

Abstract: A biopsy device includes a first cannula disposed co-axially with a second cannula. A ratchet drive mechanism is operatively coupled to the first cannula and the second cannula. The ratchet drive mechanism includes a first gear, a second gear and a torsion spring. The first gear is fixedly attached to the first cannula. The second gear is fixedly attached to the second cannula. A second side surface of the second gear is oriented to face a first side surface of the first gear. The torsion spring is interposed between the first gear and the second gear. The torsion spring has a first end portion inserted into a hole of the first gear and has a second end portion inserted into a hole of the second gear. The torsion spring stores energy which when released drivably rotates one of the first gear and the second gear relative to the other.

Abstract: The present invention provides for novel acridine-like class of compounds that have demonstrated efficiency in treating cancer. The compounds of the present invention have demonstrated efficacy in binding to and antagonizing the activity of the p53 repressor, HDMX. Once administered to a cell, the compounds of the present invention bind HDMX, thereby allowing p53 to induce apoptosis of the cancerous cell. A combination of this class of compounds along with Nutlin3 provides a novel approach to treat cancers.

Abstract: The present invention is generally directed to methods, systems, and computer program products for routing order lookups from retail systems. Order data can be synchronized from the order database cache to the order database. The order database can modify an order state of one or more customer orders from the order database. An order lookup can be received from an in-store retail system channel of one or more in-store retail system channels and can indicate a database command type. A database command type can impact a state of the order database when the order data is modified. A data source can service the order lookup based on at least a timestamp of the order data associated with a customer order. A data indicator of the order data in the order lookup can be modified when the database command type impacts the state of the order database.

Abstract: Apparatuses and methods are disclosed for detecting catalyst transfer pipe plugging in a chemical plant or petrochemical plant or refinery. The catalyst transfer pipe may extend from a reactor to a catalyst collector and enable the flow of catalyst from the reactor to the catalyst collector. Specifically, one or more sensors affixed to a catalyst transfer pipe may collect sensor data for analysis. Based on one or more detected changes in the sensor data outside a range, a data collection platform may send one or more alerts and/or send one or more signals to a control platform to adjust a flow rate, a pressure differential, or perform another action to clear a developing catalyst buildup and thereby attempt to avoid a catalyst transfer pipe from becoming plugged.

Abstract: A method of dynamically adjusting a sensitivity of sensor electrodes configured for capacitive sensing in a sensing region of an input device. The input device detects a first input in the sensing region, and acquires force information about the first input via one or more force sensors coupled to the sensing region. The input device dynamically adjusts a sensitivity of the sensor electrodes based at least in part on an amplitude and duration of the force. In some aspects, the input device may increase the sensitivity of the sensor electrodes when a force of the first input exceeds a force threshold for at least a first threshold duration. In some other aspects, the input device may restore the sensitivity of the sensor electrodes to a prior configuration when no input is detected in the sensing region for at least a second threshold duration.

Abstract: An energy-absorbing assembly includes an outer assembly with an outer hollow cylindrical member, and an inner assembly with an inner hollow cylindrical member having an end disposed in the outer member. The inner and outer assemblies are axially movably engaged with each other and define first and second cavities separated by a membrane: a first cavity inside the outer hollow cylindrical member and a second cavity inside the inner hollow cylindrical member. An adjustable-size orifice is disposed between the first and second cavities, and is configured to reduce diameter in response to a stroke motion of the energy-absorbing assembly.

Abstract: Provided is a system for determining a status of at least one merchant during or after an emergency event including at least one processor to retrieve historical transaction data for at least one merchant associated with a merchant category code (MCC), determine a first transaction count for the at least one merchant based on the historical transaction data for the at least one merchant, retrieve current transaction data for the at least one merchant, determine a second transaction count for the at least one merchant based on the current transaction data for the at least one merchant, classify the at least one merchant based at least partially on a comparison between the first transaction count and the second transaction count, and display a classification of the at least one merchant based on classifying the at least one merchant. A method and computer program product are also disclosed.

Abstract: A camera device includes a camera module that captures a scene corresponding to a field of view of the camera module. A wireless power transmitter of the camera devices transmits wireless power to a battery-powered external sensing device. A transceiver is further operable for receiving from the external sensing device sensed data. A network module transmits the image and sensed data to an external networked device. A power supply receives power over a wired connection and supplies power to the camera module, transceiver, networking module and wireless transmitter. The external sensing device may be an access control device that includes a sensor for sensing the presence of a machine readable toke and reading an identifier of the physical token. The access control device further includes a lock controller for selectively locking and unlocking a physical lock.

Abstract: Compounds of Formula (I), their preparation, and use in preventing or treating a bacterial infection are disclosed.

Abstract: A compensating initialization module may be automatically inserted into a design to compensate for register retiming which changes the designs behavior under reset. The device configuration circuitry may provide an adjustment sequence length as well as a start signal to the initialization module to properly reset the retimed user logic implemented on the integrated circuit after initial configuration and unfreezing of the integrated circuit. The auto initialization module may control the c-cycle initialization process and indicate to the user logic when c-cycle initialization has completed. The user logic may subsequently begin a user-specified reset sequence. When the user-specified reset sequence ends, the user logic implemented on the integrated circuit may begin normal operations. Additionally, a user reset request may also trigger the auto initialization module to begin a reset process.

Abstract: A method of testing a semiconductor wafer comprising a scribe line and a plurality of dies. The method includes implementing a first landing pad on the scribe line and implementing a first interconnect on the scribe line and between the first landing pad and a first cluster of the plurality of dies, thereby coupling the first landing pad to the first cluster of dies. The method also includes performing the testing of the first cluster of dies using automated test equipment (ATE) coupled to a probe tip by contacting the first landing pad with the probe tip and applying an ATE resource to the first cluster of dies.

Abstract: Provided herein are methods and systems for image registration from multiple sources. A method for image registration includes rendering a common field of interest that reflects a presence of a plurality of elements, wherein at least one of the elements is a remote element located remotely from another of the elements and updating the common field of interest such that the presence of the at least one of the elements is registered relative to another of the elements.

Abstract: A device to process data packets for communication across PHY layers which are of different respective communication protocols. In an embodiment, the device includes a first protocol stack and a second protocol stack which are each for a PCIe™ communication protocol. The first protocol stack and a second protocol stack may interface, respectively, with a first physical (PHY) layer and a second PHY layer of the device. The first protocol stack and the second protocol stack may exchange packets to facilitate communications via both the first PHY layer and the second PHY layer. In another embodiment, the first PHY layer is for communication according to the PCIe™ communication protocol and the second PHY layer is for communication according to another, comparatively low power communication protocol.