Abstract: In one embodiment, the present invention includes an apparatus having an adapter to communicate according to a personal computer (PC) protocol and a second protocol. A first interface coupled to the adapter is to perform address translation and ordering of transactions received from upstream of the adapter. The first interface is coupled in turn via one or more physical units to heterogeneous resources, each of which includes an intellectual property (IP) core and a shim, where the shim is to implement a header of the PC protocol for the IP core to enable its incorporation into the apparatus without modification. Other embodiments are described and claimed.

Abstract: Methods for inhibiting angiogenesis in endothelial cells and selectively inducing apoptosis in endothelial cells via compounds which binds annexin II are provided. These compounds and methods for using these compounds are useful in the treatment of diseases or disorders characterized by unwanted angiogenesis. Also provided are pharmaceutical compositions containing a compound which binds annexin II and a pharmaceutically acceptable vehicle and methods for identifying such compounds.

Abstract: Methods and systems detect objects of interest in a spatio-temporal signal. According to one embodiment, a system processes a digital spatio-temporal input signal containing zero or more foreground objects of interest superimposed on a background. The system comprises a foreground/background separation module, a foreground object grouping module, an object classification module, and a feedback connection. The foreground/background separation module receives the spatio-temporal input signal as an input and, according to one or more adaptable parameters, produces as outputs foreground/background labels designating elements of the spatio-temporal input signal as either foreground or background. The foreground object grouping module is connected to the foreground/background separation module and identifies groups of selected foreground-labeled elements as foreground objects.

Abstract: Techniques used in an automatic failover configuration having a primary database system, a standby database system, and an observer for preventing divergence among the primary and standby database systems while increasing the availability of the primary database system. In the automatic failover configuration, the primary database system remains available even in the absence of both the standby and the observer as long as the standby and the observer become absent sequentially. The failover configuration further permits automatic failover only when the observer is present and the standby and the primary are synchronized and inhibits state changes during failover. The database systems and the observer have copies of failover configuration state and the techniques include techniques for propagating the most recent version of the state among the databases and the observer and techniques for using carefully-ordered writes to ensure that state changes are propagated in a fashion which prevents divergence.

Abstract: This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.

Abstract: The sensitivity of visually read lateral flow immunoassay tests is enhanced by adding a small quantity of fluorescing dye or fluorescing latex bead conjugates to the initial conjugate material. When the visible spectrum test line is visibly present, the test result is observed and recorded. However, in the case where the result is indeterminate, a light of an appropriate spectrum, such as a UV, visible, or infrared spectrum, is cast on the test line to excite and fluoresce the fluorescing latex beads which are bound in the test line in true positive tests to enhance the visible color at the test line.

Abstract: The present invention includes methods and devices that detect target molecules in a biological sample. The sample analysis device of the present invention includes nanoparticles. In one embodiment, the nanoparticles are directly immobilized on the surface of the sample analysis device. In another embodiment, the nanoparticles are indirectly immobilized on the surface of the sample analysis device by incorporating them in appropriate media and immobilizing the nanoparticles within a matrix.

Abstract: A method of improving adhesion between layers in the formation of a semiconductor device and integrated circuit, and the resultant intermediate semiconductor structure, which include a substrate layer with a low k insulating layer thereover. The low k insulating layer includes a treated surface area of adsorbed gaseous particles. This treated surface area is formed by flowing a gas, preferably, silane, disilane, dichlorosilane, germane or combinations thereof, over a surface of the heated low k insulating layer for adsorption of such gaseous particles onto the heated surface, wherein the insulating layer maintains its original thickness. A capping layer is then deposited directly over the insulating layer wherein the treated surface area of the insulating layer significantly improves adhesion between the insulating layers and the capping layers to prevent delamination therebetween during subsequent processing steps of forming the integrated circuit.

Abstract: A lock cylinder including a housing defining a cylindrical cavity, and a plug disposed in the cylindrical cavity and rotatable between a locked position and an unlocked position. The plug includes an inner pin chamber aligned with an outer pin chamber of the housing when the plug is in the locked position. An inner pin is housed in the inner pin chamber and is engageable with the outer pin when the plug is in the locked position, and includes an outer surface having a non-axial groove. The non-axial groove has a curved surface that defines a substantially semi-circular cross-section. An engagement member is supported by the plug and has a substantially semispherical end portion extending into the non-axial groove such that the semispherical end portion is substantially engaged with the curved surface.

Abstract: Method of removing metals from hydrocarbon feedstock using esters of carboxylic acids, and additives for the same, are provided, wherein hydrocarbon stream such as crude oil containing metals and slats thereof, such as calcium and calcium naphthenate, is mixed with an effective metal-removing-amount of an aqueous extraction-solution of non-precipitating and non-fouling additive comprising a chemical compound selected from a group consisting of methyl or ethyl or propyl or isopropyl mono- and/or di-esters of any of three carboxylic acids, such as, maleic acid, maleic anhydride, or fumaric acid or an appropriate combination of said esters, or an appropriate combination of any of said esters with any of said three acids, enabling formation of a hydrocarbonous phase and an aqueous phase containing the metal ions; and separating aqueous phase.

Abstract: A reaction-based process has been developed for the selective removal of carbon dioxide from a multicomponent gas mixture. The proposed process effects the separation of CO2 from a mixture of gases by its reaction with metal oxides. The Calcium based Reaction Separation for CO2 process consists of contacting a CO2 laden gas with calcium oxide in a reactor such that CaO captures the CO2 by the formation of calcium carbonate. Once “spent”, CaCO3 is regenerated by its calcination leading to the formation of fresh CaO sorbent. The “regenerated” CaO is then recycled for the further capture of more CO2. This process also identifies the application of a mesoporous CaCO3 structure, that attains >90% conversion over multiple carbonation and calcination cycles. Lastly, thermal regeneration (calcination) under vacuum provided a better sorbent structure that maintained reproducible reactivity levels over multiple cycles.

Abstract: An embodiment of a method of managing a computer system begins with a step of placing a virtual machine monitor on a computer. The virtual machine monitor includes an interface for a module. The method continues with a step of forming a computing platform on the computer. The virtual machine monitor provides access control to the hardware resources for software executing on the computing platform. The method concludes with a step of adding a module to the virtual machine monitor through the interface. The module modifies the access control provided by the virtual machine monitor.

Abstract: A method of operating an engine having exhaust gas recirculation from an exhaust manifold of the engine to an intake manifold of the engine, the engine in a locomotive or other vehicle car body, the engine further having an intake system turbocharger with an air-cooled intercooler, the method including cooling the exhaust gas recirculation via a first airflow generated by car body motion, cooling compressed engine induction air in the air-cooled intercooler via a second airflow, and cooling the exhaust gas recirculation via the second airflow.

Abstract: A system, kit, and service method for exhaust gas recirculation cooling are described. In one example, a removable cooling system for an engine, the engine in a vehicle car body, the system comprising: a removable package including a first exhaust gas recirculation cooler, a second exhaust gas recirculation cooler, and a third exhaust gas recirculation cooler, the first, second, and third coolers coupled together in series, where the removable package is located at a top of the vehicle car body and where the removable package is removably coupled to the vehicle as a unit.

Abstract: For years, can bottoms have been formed to provide structural integrity for cans, which include many different configurations. A novel profile for a container bottom is shown herein. The bottom structure includes a multi-radial domed central panel extending from its outside edge to a downwardly projecting substantially cylindrical inner leg portion. The inner leg portion extends to a generally semi-toroidal nose portion. The outside of the nose portion extends to an upwardly and outwardly inclined outer leg portion. The outer leg portion is connected to an outwardly inclined peripheral portion. The peripheral portion is connected to the lower end of the generally cylindrical sidewall portion.

Abstract: System and methods of increasing reliability of determined location information by using two integration filters are provided. An exemplary embodiment integrates inertial navigation system information and global navigation satellite system (GNSS) information in a real time Kalman filter; determines a real time location of the aircraft with the real time Kalman filter based upon the INS information and the GNSS information; delays the GNSS information by an interval; integrates the INS information and the delayed GNSS information in a delay Kalman filter; determines a predictive location of the aircraft with the delay Kalman filter based upon the INS information, the delayed GNSS information, and the interval; and in response to an inaccuracy of the real time location determined from the real time Kalman filter, selects the predictive location determined from the delay Kalman filter as a new real time location of the aircraft.

Abstract: The invention relates to an improved therapy for treating resistant bacterial infections caused by extended-spectrum ?-lactamase (ESBLs)-producing strains in a warm-blooded animal, adjuvant step down therapy, and pharmaceutical compositions for such therapies. The invention also relates to a method for inhibiting bacterial resistance in ESBLs-producing strains so as to have better control over the therapy; achieve reduced hospital stay and adjuvant step down therapy so as to avoid recrudescence. In particular, the therapy includes antibacterial combination of cefepime with sulbactam via parenteral route, followed by oral third generation cephalosporin with a suitable ? lactamase inhibitor.

Abstract: There is provided an integrated injector subassembly or kit. The integrated injector kit comprises: Y-tubing comprising an output arm that is for releasable connection with a patient line and first and second input arms that each independently and integrally connect with an output port of first and second fluid control valves; each fluid control valve comprising: (a) the output port that is integrally connected to one of the first and second input arms of the Y-tubing; (b) an inlet port for connection with a container of a contrast agent or saline and for receiving the contrast agent or saline; and (c) a syringe port for connection with a syringe; and each pairing of fluid control valve and input arm of the Y-tubing defining a fluid path comprising at least one back check valve.

Abstract: An SAR ADC provides increased immunity to noise introduced by time varying noise components provided on reference potentials (VREF). Reference voltage noise contributions are canceled by introducing a reference voltage component to a pair of binary weighted capacitor arrays (NDAC and PDAC) during bit trials, which are presented to a differential comparator as a common mode signal and rejected. During sampling, select elements in either the PDAC or the NDAC also obtain a reference voltage contribution. Although the sampled VREF signal may have a noise contribution, the noise is fixed at the time of bit trials, which can improve performance. Generally, the scheme provides a 50% reduction in noise errors over the prior art for the same VREF noise. Additional embodiments described herein can reduce noise errors to 25% or even 12.5% over prior art systems.

Abstract: This document discusses, among other things, a user interface capable of resolving interactions between programmable parameters for operation of a personal medical device. Programming these devices is a difficult task when many parameters are involved. The medical device interface attempts to reduce and minimize constraint violations between interdependent parameters using an initial set of parameter values supplied by user (typically a physician) input, and constraint violations describing invalid parameter values. A user is given the option to select one or more parameters to remain constant. If possible, a set of parameter values with less egregious constraint violations is displayed to the user. A user is prompted to accept the set of parameter values and program the medical device.