Abstract: The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the disease free survival and/or response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.

Abstract: A device for utilizing waste heat of an internal combustion engine. A heat exchanger of a circuit of a working medium is provided in its exhaust system. A pump is connected upstream from the heat exchanger, the circuit containing an expansion machine. A coupling heat exchanger is located in the circuit of the working medium, the working medium of the circuit and the cooling medium of the internal combustion engine flowing through the coupling heat exchanger.

Abstract: A device for utilizing the waste heat of an internal combustion includes a single-stage or multi-stage supercharging device, which is designed as an exhaust-gas turbocharger in particular. The single-stage or multi-stage supercharging device is assigned an additional supercharging device including an expansion machine acted upon by an auxiliary circuit, in particular a steam circuit.

Abstract: An internal combustion engine having an exhaust gas recirculation device for recirculating exhaust gas of the internal combustion engine to a fresh-air side of the internal combustion engine. For this purpose, it is provided that the exhaust gas recirculation device has at least one compressor for compressing the exhaust gas supplied to the fresh-air side of the internal combustion engine.

Abstract: The invention relates to a steam turbine (10), in particular for using the waste heat of an internal combustion engine (2), comprising at least one rotor (26) and at least one stator (20), said stator (20) comprising at least two nozzles (22) which are arranged in parallel in relation to each other. The nozzles (22) are designed for different load points of the rotor (26) and can be switched on and off independently from each other.

Abstract: A thermoelectric generator and a method for manufacturing a thermoelectric generator are described. The thermoelectric generator, having a housing in which at least one heat source tube, at least one heat sink tube, and at least one generator element are between the heat source tube and the heat sink tube. A pretension mounting device is in the housing and provides an elastic force via which the tubes are pretensioned relative to one another and which compresses the tubes and the generator element in-between. An inner side of the housing of the pretension mounting device forms a support for the pretension mounting device, which is acted upon by a counterforce to the elastic force of the pretension mounting device.

Abstract: Methods for providing, at the discretion of the user, at least two different oxidative hair coloring compositions providing different level of lift based on a single tint component. The methods involve the use of a tint component, an oxidizing component and a third component comprising a non-ammonia alkalizing agent. The compositions may comprise little or no ammonia.

Abstract: This invention relates to the production of specific antibodies for the detection of human tumor associated urokinase-type plasminogen activator receptor (uPAR) deletion variants in biological samples as well as to their diagnostic and therapeutic application.

Abstract: The present invention relates to an oxidizing composition for treatment of keratin fibers comprising a combination of; (a) at least one anionic associative copolymer, (b) at least one anionic non associative copolymer; (c) at least one peroxide agent; (d) at least one persulfate agent; (e) at least on alkalizing agent; and (f) a carrier medium suitable for hair treatment. The oxidizing composition described is suitable for composition used in conventional hair treatments such as dyeing, bleaching, and permanent waving or relaxing/straightening of the keratinous fibers, particularly human hair, requiring an oxidizing composition.

Abstract: Methods for providing, at the discretion of the user, at least two different oxidative hair coloring compositions providing different level of lift based on a single tint component. The methods involve the use of a tint component, an oxidizing component and a third component comprising a non-ammonia alkalizing agent. The compositions may comprise little or no ammonia.

Abstract: A method for colouring hair, wherein the method comprises: (i) the formation of a first plurality of coated hair fibre portions, wherein the coating comprises a first composition, wherein the first composition comprises a first hair colouring agent, a hydrophobic phase, a hydrophilic phase, a surfactant, and a thickener capable of interacting with the hydrophobic phase and the hydrophilic phase; and subsequently (ii) styling the hair wherein the first plurality of coated hair fibre portions is contacted with a second plurality of hair fibre portions; wherein the method does not comprise the application of a solid barrier means in order to separate the first plurality of coated hair fibre portions from the second plurality of hair fibre portions, and wherein the first composition is substantially free of persulfate.

Abstract: In a Laval nozzle (10) having a flow channel (12), which has a flow cross-section (14) extending in a convergent-divergent manner, according to the invention the flow channel (12) comprises mutually opposing first flow channel walls (16, 16?), which are formed by two nozzle bodies (18, 18?) spaced a fixed distance apart from one another. Two mutually opposite second flow channel walls (20, 20?), which can be moved relative toward one another or away from one another for adjusting the flow cross-section (14) of the flow channel (12), are disposed between the nozzle bodies (18, 18?).

Abstract: Oxidative hair coloring compositions comprising a non-ammonia alkalizing agent, such as monoethanolamine, and hydrogen peroxide in a specific ratio. The compositions of the invention have a relatively high lift power for relatively low hair damage. The compositions may comprise little or no ammonia.

Abstract: The present invention relates to an oxidizing composition for treatment of keratin fibers comprising a combination of; (a) at least one anionic associative copolymer, (b) at least one anionic non associative copolymer; (c) at least one peroxide agent; (d) at least one persulfate agent; (e) at least on alkalizing agent; and (f) a carrier medium suitable for hair treatment. The oxidizing composition described is suitable for composition used in conventional hair treatments such as dyeing, bleaching, and permanent waving or relaxing/straightening of the keratinous fibers, particularly human hair, requiring an oxidizing composition.

Abstract: The present invention relates to an oxidizing composition for treatment of keratin fibers comprising a combination of; (a) at least one anionic associative copolymer, (b) at least one anionic non associative copolymer; (c) at least one peroxide agent; (d) at least one persulfate agent; (e) at least on alkalizing agent; and (f) a carrier medium suitable for hair treatment. The oxidizing composition described is suitable for composition used in conventional hair treatments such as dyeing, bleaching, and permanent waving or relaxing/straightening of the keratinous fibers, particularly human hair, requiring an oxidizing composition.

Abstract: For operating an internal combustion engine having a throttle situated in an exhaust line or exhaust return line, in which a heat engine is driven by a quantity of heat produced by the internal combustion engine, in a first non-heating operating mode of the internal combustion engine, a first setpoint value is preset, a first operating parameter that characterizes a temperature of the internal combustion engine is detected, a first triggering value is determined for the triggering of the at least one throttle as a function of the first setpoint value and the first operating parameter, the at least one throttle is triggered in accordance with the first triggering value, and the at least one heat engine is driven by the resulting quantity of heat.

Abstract: An internal combustion engine having an exhaust gas recirculation device for recirculating exhaust gas of the internal combustion engine to a fresh-air side of the internal combustion engine. For this purpose, it is provided that the exhaust gas recirculation device has at least one compressor for compressing the exhaust gas supplied to the fresh-air side of the internal combustion engine.

Abstract: A device for utilizing waste heat of an internal combustion engine. A heat exchanger of a circuit of a working medium is provided in its exhaust system. A pump is connected upstream from the heat exchanger, the circuit containing an expansion machine. A coupling heat exchanger is located in the circuit of the working medium, the working medium of the circuit and the cooling medium of the internal combustion engine flowing through the coupling heat exchanger.

Abstract: Oxidative hair coloring compositions comprising a non-ammonia alkalizing agent, such as monoethanolamine, and hydrogen peroxide in a specific ratio. The compositions of the invention have a relatively high lift power for relatively low hair damage. The compositions may comprise little or no ammonia.

Abstract: Methods for providing, at the discretion of the user, at least two different oxidative hair coloring compositions providing different level of lift based on a single tint component. The methods involve the use of a tint component, an oxidizing componnt and a third component comprising a non-ammonia alkalizing agent. The compositions may comprise little or no ammonia.