Patents by Inventor Manfred Schmitt

Manfred Schmitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120184455
    Abstract: The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
    Type: Application
    Filed: January 17, 2012
    Publication date: July 19, 2012
    Applicant: Epigenomics AG
    Inventors: John Foekens, Nadia Harbeck, Thomas Koenig, Sabine Maier, John Martens, Fabian Model, Inko Nimmrich, Tamas Rujan, Armin Schmitt, Manfred Schmitt, Maxime P. Look, Almuth Marx, Heinz Hoefler
  • Publication number: 20120144825
    Abstract: A device for utilizing the waste heat of an internal combustion includes a single-stage or multi-stage supercharging device, which is designed as an exhaust-gas turbocharger in particular. The single-stage or multi-stage supercharging device is assigned an additional supercharging device including an expansion machine acted upon by an auxiliary circuit, in particular a steam circuit.
    Type: Application
    Filed: June 22, 2010
    Publication date: June 14, 2012
    Inventors: Juergen Stegmaier, Martin Cichon, Manfred Schmitt, Bernd Banzhaf, Achim Schmidt
  • Publication number: 20120103379
    Abstract: A thermoelectric module having a plurality of p-n-couples, every two adjacent p-n-legs forming one p-n-couple. The p-n-legs are each manufactured from conductive materials. The p-n-legs of the plurality of p-n-couples are separated in an alternating sequence by an electrically insulating gap which creates a meandering current flow.
    Type: Application
    Filed: November 2, 2011
    Publication date: May 3, 2012
    Inventors: Ilona Krinn, Wolfgang Stoecklein, Manfred Schmitt, Ludwig Kemmler
  • Patent number: 8101359
    Abstract: The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
    Type: Grant
    Filed: October 1, 2003
    Date of Patent: January 24, 2012
    Assignee: Epigenomics AG
    Inventors: John Foekens, Nadia Harbeck, Thomas Koenig, Sabine Maier, John W. Martens, Fabian Model, Inko Nimmrich, Tamas Rujan, Armin Schmitt, Manfred Schmitt, Maxime P. Look, Almuth Marx, Heinz Hoefler
  • Publication number: 20110311465
    Abstract: The present invention relates to an oxidizing composition for treatment of keratin fibers comprising a combination of; (a) at least one anionic associative copolymer, (b) at least one anionic non associative copolymer; (c) at least one peroxide agent; (d) at least one persulfate agent; (e) at least on alkalizing agent; and (f) a carrier medium suitable for hair treatment. The oxidizing composition described is suitable for composition used in conventional hair treatments such as dyeing, bleaching, and permanent waving or relaxing/straightening of the keratinous fibers, particularly human hair, requiring an oxidizing composition.
    Type: Application
    Filed: May 19, 2011
    Publication date: December 22, 2011
    Inventors: Wilfried BURG, Matthias Morand, Anette Sallwey, Manfred Schmitt
  • Publication number: 20110288267
    Abstract: In a method for cleaning an absorptive polyester, the polymer is dissolved in a first solvent (12) and subsequently the polymer solution is brought into tight contact with a second solvent (41) in a turbulent shear field under the influence of strong shear forces. Here, the second solvent (41) represents a non-solvent for the absorptive polyester and is mixable with the first solvent (12) to an unlimited extent. Subsequently, the polymer suspension resulting from the addition of the second solvent (41) is conveyed onto or into a rotating, cylindrical screen body (71) of a drum shear screen (70) and then the moist polymer mass is removed from the screen body (71) and subsequently dried. The method is suitable for the production of absorptive polyester with a high degree of quality and may be performed in a cost-effective fashion on an industrial scale as well.
    Type: Application
    Filed: February 22, 2011
    Publication date: November 24, 2011
    Applicant: Evonik Roehm GmbH
    Inventors: Anja Enderle, Manfred Schmitt
  • Publication number: 20110179793
    Abstract: A method for operating an internal combustion engine (10) having a steam power plant (12), in which the exhaust gas of the internal combustion engine (10) at least indirectly heats the steam and this steam drives a turbine (26), the steam power plant (12) being sometimes, in particular at the beginning of operation, initially operated in a protection operating mode, in which the protection of the turbine (26) from damage by water droplets has priority.
    Type: Application
    Filed: January 24, 2011
    Publication date: July 28, 2011
    Applicant: ROBERT BOSCH GMBH
    Inventors: Juergen Stegmaier, Manfred Schmitt
  • Publication number: 20110144301
    Abstract: In a method for cleaning an absorptive polyester, the polymer is dissolved in a first solvent (12) and subsequently the polymer solution is brought into tight contact with a second solvent (41) in a turbulent shear field under the influence of strong shear forces. Here, the second solvent (41) represents a non-solvent for the absorptive polyester and is mixable with the first solvent (12) to an unlimited extent. Subsequently, the polymer suspension resulting from the addition of the second solvent (41) is conveyed onto or into a rotating, cylindrical screen body (71) of a drum shear screen (70) and then the moist polymer mass is removed from the screen body (71) and subsequently dried. The method is suitable for the production of absorptive polyester with a high degree of quality and may be performed in a cost-effective fashion on an industrial scale as well.
    Type: Application
    Filed: February 22, 2011
    Publication date: June 16, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Anja ENDERLE, Manfred SCHMITT
  • Publication number: 20110094590
    Abstract: In a method for operating a fluid valve for controlling or regulating a fluid, having at least one movable valve component is displaceable with the aid of at least one electrical actuating signal which contains at least one first actuating signal portion which causes an oscillating valve motion of the valve component. Pressure oscillations generated in the fluid due to the oscillating valve motion are detected, and are used for regulation of the oscillating valve motion caused by the first actuating signal portion.
    Type: Application
    Filed: May 28, 2009
    Publication date: April 28, 2011
    Inventors: Juergen Hessenauer, Jose Kissler, Ulrich Foerch, Manfred Schmitt, Steffen Schumacher, Nicole Weber, Oliver Schell, Christof Ott
  • Publication number: 20100137550
    Abstract: In a method for cleaning an absorptive polyester, the polymer is dissolved in a first solvent (12) and subsequently the polymer solution is brought into tight contact with a second solvent (41) in a turbulent shear field under the influence of strong shear forces. Here, the second solvent (41) represents a non-solvent for the absorptive polyester and is mixable with the first solvent (12) to an unlimited extent. Subsequently, the polymer suspension resulting from the addition of the second solvent (41) is conveyed onto or into a rotating, cylindrical screen body (71) of a drum shear screen (70) and then the moist polymer mass is removed from the screen body (71) and subsequently dried. The method is suitable for the production of absorptive polyester with a high degree of quality and may be performed in a cost-effective fashion on an industrial scale as well.
    Type: Application
    Filed: May 2, 2008
    Publication date: June 3, 2010
    Applicant: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG
    Inventors: Anja Enderle, Manfred Schmitt
  • Publication number: 20100058759
    Abstract: For operating an internal combustion engine having a throttle situated in an exhaust line or exhaust return line, in which a heat engine is driven by a quantity of heat produced by the internal combustion engine, in a first non-heating operating mode of the internal combustion engine, a first setpoint value is preset, a first operating parameter that characterizes a temperature of the internal combustion engine is detected, a first triggering value is determined for the triggering of the at least one throttle as a function of the first setpoint value and the first operating parameter, the at least one throttle is triggered in accordance with the first triggering value, and the at least one heat engine is driven by the resulting quantity of heat.
    Type: Application
    Filed: May 7, 2009
    Publication date: March 11, 2010
    Inventors: Guillaume Huard, Juergen Stegmaier, Henrick Brandes, Martin Cichon, Manfred Schmitt, Lutz Rauchfuss, Oliver Tschismar
  • Publication number: 20090202504
    Abstract: This invention relates to the production of specific antibodies for the detection of human tumor associated urokinase-type plasminogen activator receptor (uPAR) deletion variants in biological samples as well as to their diagnostic and therapeutic application.
    Type: Application
    Filed: June 30, 2008
    Publication date: August 13, 2009
    Applicant: WILEX AG
    Inventors: Thomas LUTHER, Viktor Magdolen, Manfred Schmitt, Bernd Muhlenweg, Matthias Kotzsch
  • Publication number: 20090111707
    Abstract: The present invention relates to methods for predicting the outcome of anthracycline treatment of cell proliferative disorder patients. This is achieved by determining the expression level of at least one gene selected from the group consisting of PITX2; TFF1 and PLAU. The invention also relates to sequences, oligonucleotides and antibodies which can be used within the described methods.
    Type: Application
    Filed: September 21, 2006
    Publication date: April 30, 2009
    Applicant: Epigenomics AG
    Inventors: John Foekens, John Martens, Serenella Eppenberger-Castori, Vincent Vuaroqueaux, Frederique Spyratos, Nadia Harbeck, Manfred Schmitt, Heinz Hoefler, Sabine Maier, Gunter Weiss, Ralf Lesche, Thomas Hildmann, Achim Plum
  • Publication number: 20080254447
    Abstract: The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the disease free survival and/or response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
    Type: Application
    Filed: December 13, 2004
    Publication date: October 16, 2008
    Applicant: Epigenomics AG
    Inventors: John Foekens, Nadia Harbeck, Thomas Koenig, Sabine Maier, John Martens, Fabian Model, Inko Nimmrich, Manfred Schmitt, Ralf Lesche, Dimo Dietrich, Volkmar Mueller, Antje Kluth, Ina Schwope, Oliver Hartmann, Peter Adorjan, Almuth Marx, Heinz Hoefler
  • Patent number: 7407751
    Abstract: This invention relates to the production of specific antibodies for the detection of human tumor associated urokinase-type plasminogen activator receptor (uPAR) deletion variants in biological samples as well as to their diagnostic and therapeutic application.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: August 5, 2008
    Assignee: Wilex AG
    Inventors: Thomas Luther, Viktor Magdolen, Manfred Schmitt, Matthias Kotzsch
  • Patent number: 7399468
    Abstract: The invention concerns a method and a reagent kit for detecting cells in a biological sample using a double-fluorescence technique and the diagnostic and therapeutic application of amino acid sequence-specific antibodies against the urokinase receptor having a high affinity for tumour cell-expressed receptors.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: July 15, 2008
    Assignee: Wilex AG
    Inventors: Thomas Luther, Martin Mueller, Sybille Albrecht, Viktor Magdolen, Olaf Wilhelm, Manfred Schmitt, Nadja Harbeck
  • Patent number: 7334693
    Abstract: A biased support for booms that can pivot about a pin, for pivoting travel tracks for vehicles that run on rails, such as trolley travel tracks on booms. The booms are mounted to pivot via pins, the lock on the boom and slide plates on the upper and lower bearing points of the lock. At least one of the two slide plates in the upper bearing point is mounted elastically, so that when the boom is pivoted into the operating position, the entire lock is biased vertically and the pin is relieved of stress.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: February 26, 2008
    Assignee: Noell Crane Systems GmbH
    Inventors: Conrad Müller, Alexander Hoffmann, Manfred Schmitt
  • Publication number: 20070227997
    Abstract: A biased support for booms that can pivot about a pin, for pivoting travel tracks for vehicles that run on rails, such as trolley travel tracks on booms. The booms are mounted to pivot via pins, the lock on the boom and slide plates on the upper and lower bearing points of the lock. At least one of the two slide plates in the upper bearing point is mounted elastically, so that when the boom is pivoted into the operating position, the entire lock is biased vertically and the pin is relieved of stress.
    Type: Application
    Filed: March 16, 2007
    Publication date: October 4, 2007
    Inventors: Conrad Muller, Alexander Hoffmann, Manfred Schmitt
  • Publication number: 20070067926
    Abstract: The present patent application relates to an agent for oxidative coloring of keratin fibers, containing a combination of 2-amino-5-ethylphenol and at least one m-aminophenol of general Formula (I) wherein R1=H or C2H4OH; R2=CH3 or C2H5, and R3=H or CH3; wherein R2 is not equal to CH3, if R1 and R3 equal H; or physiologically compatible, water-soluble salts thereof.
    Type: Application
    Filed: September 20, 2006
    Publication date: March 29, 2007
    Inventors: Manfred Schmitt, Gabricle de Waal, Annelie Dohling, Andreas Pfefferkorn
  • Publication number: 20070068407
    Abstract: A sheet-guiding device in a feed region of a sheet-processing machine includes a suction head settable to a format length of a sheet and flexible sheet-guiding elements disposed above a sheet conveying plane. The sheet-guiding elements have a constant length, are disposed so as to be stationary and are deflectable by a positional change of the suction head.
    Type: Application
    Filed: September 28, 2006
    Publication date: March 29, 2007
    Inventor: Manfred Schmitt