Abstract: The technology described herein is directed to methods for detection of microbes and microbe components. In some embodiments of any of the aspects, the methods comprise methods of microbe isolation, sample preparation, mass spectrometry, or analysis. In some embodiments of any of the aspects, such methods can be applied to detect at least one microbe or at least one microbial component in a sample, including not limited to a patient sample, an animal model sample, an environmental sample, or a non-biological sample.

Abstract: A digital identity, which may include a user interface that may be displayed on a mobile computing device, may be generated to include information extracted from a physical identification card (e.g., driver license or passport), as well as information regarding validation of the physical identification card and of the consumer's identity. The digital identity may be used in place of the physical identification card.

Abstract: A fuse including a fuse body having first and second end faces at opposing first and second longitudinal ends thereof, each of the first and second end faces having at least one notch formed therein, a fusible element extending through the fuse body and having a first end bent over the first end face and disposed within the at least one notch in the first end face and a second end bent over the second end face and disposed within the at least one notch in the second end face, and a first endcap disposed on the first longitudinal end of the fuse body and a second endcap disposed on the second longitudinal end of the fuse body, wherein the first and second endcaps flatly abut the first and second end faces without interference from the fusible element.

Abstract: In an embodiment, a computing system, such as a monitoring computer, receives a request from a user to monitor an account of the user with an online service provider. The request may include personal information and user preferences for one or more protective actions. The system periodically monitors external data sources for indications of changes to personal information associated with the account, and detects changes or attempted changes to personal information associated with the account. The system may determine risk levels associated with detected changes or attempted changes, and transmit a notification to the user via a communication channel selected based on the determined risk level and/or the user preferences. The system may also initiate protective actions, so that further unauthorized access to the account may be prevented.

Abstract: The present invention relates to a reaction mixture for manufacturing an inorganic-filler based closed-cell rigid polyurethane or polyisocyanurate (PU or PIR) containing foam having a calorific value below 6 MJ/kg, preferably below 4.5 MJ/kg, more preferably below 3 MJ/kg, measured according to EN ISO 1716, the reaction mixture comprising: At least one polyisocyanate-containing compound; At least one isocyanate-reactive compound; An inorganic filler composition; At least one physical blowing agent; characterised in that said inorganic filler composition has bulk density higher than 2 g/cm3, preferably higher than 2.1 g/cm3, more preferably higher than 2.2 g/cm3, even more preferably higher than 2.4 g/cm3.

Abstract: Systems and methods are provided for assessing an account takeover risk for one or more accounts of an individual. The account security procedures for each of a number of services with which the user has an account may be analyzed. Publicly accessible information regarding the user may also be collected and analyzed. The collected information and security procedures may be compared in order to determine one or more vulnerabilities to hostile account takeover of one or more of the analyzed accounts. An alert may be generated regarding a determined takeover risk, which may include suggested actions for remedying the risk.

Abstract: A process for synthesising hydrocarbons is described comprising the steps of (a) making a synthesis gas comprising hydrogen, carbon monoxide and carbon dioxide from a feedstock in a synthesis gas generation unit, (b) removing carbon dioxide to produce a carbon dioxide stream and purified synthesis gas comprising hydrogen and carbon monoxide for synthesis gas in a Fischer-Tropsch hydrocarbon synthesis unit wherein (i) at least a portion of the FT water stream is fed to an electrolysis unit to provide an oxygen stream, which is fed to the synthesis gas generation unit. Carbon dioxide stream recovered from the carbon dioxide removal unit and a portion of the hydrogen stream produced by the electrolysis unit are fed to a reverse water-gas shift unit to produce a carbon monoxide stream, with carbon monoxide stream from the reverse water-gas shift unit fed to the Fischer-Tropsch hydrocarbon synthesis unit.

Abstract: Embodiments disclosed herein include methods of developing a metal oxo photoresist. In an embodiment, the method comprises providing a substrate with the metal oxo photoresist into a vacuum chamber, where the metal oxo photoresist comprises exposed regions and unexposed regions. In an embodiment, the unexposed regions comprise a higher carbon concentration than the exposed regions. The method may further comprise vaporizing a halogenating agent into the vacuum chamber, where the halogenating agent reacts with either the unexposed regions or the exposed regions to produce a volatile byproduct. In an embodiment, the method may further comprise purging the vacuum chamber.

Abstract: The present invention relates to compounds that inhibit KRas G12D, In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: A system for modeling the evolution of a system over time using an advection-based process is provided. The system continuously evolves a probability density function (“PDF”) for a characteristic of a characteristic of the state of the system and its time-varying parameters. The PDF is evolved based on advection by solving an advection partial differential equation that is based on a system model of the system. The system model has time-varying parameters for modeling the characteristic of the state of the system. The system uses the continuously evolving PDF to make predictions about the characteristic of the state of the system.

Abstract: A process for producing a gas stream comprising carbon monoxide comprising the steps of (a) feeding a gas mixture comprising carbon dioxide and hydrogen to a burner and combusting it with a sub-stoichiometric amount of an oxygen gas stream to form a combusted gas mixture comprising carbon monoxide, carbon dioxide, hydrogen and steam, (b) passing the combusted gas mixture through a bed of reverse water-gas shift catalyst to form a crude product gas mixture containing carbon monoxide, steam, hydrogen and carbon dioxide, (c) cooling the crude product gas mixture to below the dew point and recovering a condensate to form a dewatered product gas, (d) removing carbon dioxide from the dewatered product gas in a carbon dioxide removal unit to form the gas stream comprising carbon monoxide, and (e) combining carbon dioxide recovered by the carbon dioxide removal unit with the gas mixture comprising hydrogen and carbon dioxide.

Abstract: A demister for a gearing system includes a main body having an inner annular rim coupled to an outer annular rim through a first wall and a second wall opposite from the first wall. The main body is configured to be rotated about a central longitudinal axis to create centrifugal forces that separate oil mist particles from air. First fluid passages extend radially between and through the inner annular rim and the outer annular rim. The first fluid passages include a fluid inlet opening in the outer annular rim and a fluid outlet opening in the inner annular rim. The fluid inlet opening is configured to accept incoming air. The fluid outlet opening is configured to discharge filtered air.

Abstract: A system maintains a knowledge layout to support the building of event response recommendations. Meta-graph patterns may be used to determine semantic relatedness between events and actions in response. Event-action node pairs are then constructed.

Abstract: The invention provides an omnidirectional treadmill system that uses an inner core which is inflated within a tread membrane. On the outside surface of the inflated inner core are ball casters which push outward against the interior of the membrane, resulting in a low friction barrier between the inner core and the inside surface of the tread membrane. The tread membrane rests on a sphere directly below the user in the center of the device. When the sphere is rotated it drives the tread around the stationary inner core. The sphere rotation is accomplished using a holonomic drive system such as motorized omni wheels. The device uses an enclosure which encircles the tread area. The enclosure serves two purposes: to enhance safety of the user and to provide a surface for image projection to the user in virtual reality applications.

Abstract: Provided herein are composite materials comprising a layup consisting of one or more surfacing sheets comingled with a carbon fiber non-woven mat. The surfacing sheet may comprise polyamide-6 and the carbon fiber non-woven mat may comprise carbon fibers that have been recycled. The surfacing sheets comprise sub-micron scale particles for reducing the thermal expansion coefficient of the surfacing sheets. The resulting layup is suitable for use in the formation of articles, particularly articles requiring a smooth finish absent of defects caused by underlying surfaces having irregular compositions or textures.

Abstract: A charged particle buncher includes a series of spaced apart electrodes arranged to generate a shaped electric field. The series includes a first electrode, a last electrode and one or more intermediate electrodes. The charged particle buncher includes a waveform device attached to the electrodes and configured to apply a periodic potential waveform to each electrode independently in a manner so as to form a quasi-electrostatic time varying potential gradient between adjacent electrodes and to cause spatial distribution of charged particles that form a plurality of nodes and antinodes. The nodes have a charged particle density and the antinodes have substantially no charged particle density, and the nodes and the antinodes are formed from a charged particle beam configured to hit the target.

Abstract: Embodiments disclosed herein include methods of developing a metal oxo photoresist. In an embodiment, the method comprises providing a substrate with the metal oxo photoresist into a vacuum chamber, where the metal oxo photoresist comprises exposed regions and unexposed regions. In an embodiment, the unexposed regions comprise a higher carbon concentration than the exposed regions. The method may further comprise vaporizing a halogenating agent into the vacuum chamber, where the halogenating agent reacts with either the unexposed regions or the exposed regions to produce a volatile byproduct. In an embodiment, the method may further comprise purging the vacuum chamber.

Abstract: Methods and apparatus for self-assembled monolayer (SAM) deposition are provided herein. In some embodiments, an apparatus for self-assembled monolayer (SAM) deposition includes: a chamber enclosing a processing volume; a substrate support disposed in the chamber and configured to support a substrate in the processing volume; a gas distribution system coupled to the chamber and configured to distribute a process gas into the processing volume; a first SAM precursor source fluidly coupled to the gas distribution system to provide a first SAM precursor as a part of the process gas; and a second SAM precursor source fluidly coupled to the gas distribution system to provide a second SAM precursor, different than the first SAM precursor, as a part of the process gas, wherein the first and second SAM precursor sources are independently controllable to control a relative percentage of the first and second SAM precursors in the process gas with respect to each other.

Abstract: In various example embodiments, a system and method for adjusting a user interface according to a cognitive mode is disclosed. In one example embodiment, a method includes receiving a plurality of user events based on a user interacting with a system, determining a cognitive operating mode of the user based on the user events, with the cognitive operating mode selected from a predefined set of cognitive operating modes, and modifying a user interface element according to the cognitive operating mode of the user.