Abstract: A generator includes an internal combustion engine including an engine block including a cylinder including a piston, a crankshaft configured to rotate about a crankshaft axis in response to movement by the piston, and a spark plug configured to periodically generate a spark to ignite fuel in the cylinder to control the movement of the piston. The generator further includes an alternator including a rotor and a stator, the rotor configured to rotate with the rotation of the crankshaft to generate alternating current electrical power, a controller configured to control a rate of fuel supply to the internal combustion engine, and a switch configured to selectively enable the flow of a first type of fuel into the cylinder and disable the flow of a second type of fuel, wherein the controller is configured to receive an indication of a fuel type based on a position of the switch.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), having the core structure: pharmaceutical compositions containing at least one such modulator, methods of treatment of mediated diseases, such as cystic fibrosis, using such modulators and pharmaceutical compositions, combination pharmaceutical compositions and therapies comprising such modulators, and processes and intermediates for making such modulators.

Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) having the structure: (I), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis using such modulators and pharmaceutical compositions, combination therapies, and processes and intermediates for making such modulators.

Abstract: The present invention is related generally to recovering metals from waste electronics, and more particularly to a process to recover copper and gold commonly found in waste printed circuit boards using a lixiviant containing a weak acid such as citric acid or acetic acid, a particular concentration of table salt and an oxidizer. By using this lixiviant, the copper found in the printed circuit board reacts to form copper salts and gold becomes detached. Importantly this recovery method of copper and gold found in waste PCBs is fast, does not pose environmental hazards and is economically feasible.

Abstract: In various embodiments, a gradient modeling application automatically generates designs of three-dimensional (3D) objects. The gradient modeling application generates a set of points based on a resolution and a perimeter. The gradient modeling application computes a set of displacement values based on the set of points, a first two-dimensional (2D) border, and a first displacement parameter that is associated with the first 2D border. Based on the set of displacement values, the gradient modeling application generates a 3D object design.

Abstract: Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes.

Abstract: A manufacturing system is disclosed including a conveying apparatus with a plurality of rollers that form a travel path along which a ribbon is configured to be conveyed in a travel direction. The plurality of rollers including at least a tensioning roller having a shaft and a rotation wheel with a plurality of spokes that extend radially outward from the shaft, the plurality of spokes being configured to rotate about a longitudinal axis of the shaft to cause the ribbon to be conveyed in the travel direction. The manufacturing system further including a flow generator configured to direct a flow of fluid to the plurality of spokes to cause rotation of the plurality of spokes.

Abstract: A system comprises a first sensor for generating a swelling signal based on the user pressing on the first sensor with a body part, a second sensor for generating a blood signal which is indicative of the volume of blood in the body part when the user presses on the first sensor and a force sensor for measuring the force applied by the body part to the first sensor when the user presses on the first sensor. The system also comprises a processor configured to determine an indication of swelling for the body part based on the swelling signal when the force sensor measures a first pre-determined value, determine an indication of blood pressure at the body part based on a force value measured by the force sensor when the blood signal reaches a second pre-determined value.

Abstract: A drink making device including a hood, a base configured to support at least four bottles, a tower connecting the base and the hood; and a dispenser for dispensing a beverage. The hood includes at least four attachment connectors. Liquid from the bottles is selectively pumped through the connectors through the dispenser to dispense a beverage.

Abstract: Apparatuses and methods for heating moving continuous glass ribbons at desired lines of separation and/or for separating glass sheets from continuous glass ribbons are disclosed. An apparatus includes a translatable support portion and a heating apparatus coupled to the support portion. The heating apparatus is configured to contact the continuous glass ribbon across at least a portion of a width of the continuous glass ribbon at the desired line of separation as the support portion moves in a draw direction, thereby preferentially applying heat to a first side of the continuous glass ribbon at the desired line of separation as the continuous glass ribbon moves in the draw direction.

Abstract: Systems and methods for identifying a motor coupled to an electrical appliance are disclosed herein. The electrical appliance can include a motor assembly comprising at least one electric motor and a filter network including an electrical resistance component and an electrical capacitance component. The electrical appliance can also include a controller electrically coupled to the motor assembly and the filter network, the controller comprising one or more processors and a memory comprising instructions for performing a process. The process can include providing an input signal to the filter network and receiving an output signal from the filter network, the output signal being filtered by the filter network. The process can also include identifying a filter characteristic of the filter network based on the output signal and identifying a type of the electric motor based on the identified filter characteristic.

Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) having the core structure: pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis using such modulators and pharmaceutical compositions, combination therapies, and processes and intermediates for making such modulators.

Abstract: Disclosed in certain embodiments are systems for removing pollutants from an air flow, which may include a substrate and a catalyst-adsorbent material disposed on the substrate.

Abstract: The present invention relates to patient positioning. In order to improve patient positioning during a scan, an autonomous motion positioner is proposed using a critical range, which may correspond to maximum corrections achievable by the scanner hardware and the maximum tolerable image distortions. The critical range is determined based on one or more machine settings of the medical imaging system. As the machine setting(s) may vary in a given imaging exam, the critical range may dynamically change in response to a change of the machine setting in the given imaging exam. External sensors may measure, via a feedback loop, the deviation from the start position, i.e. the imaging pose position. If patient motion is too large and the motion parameter (e.g. translation and/or rotation) exceeds the determined critical range, then the scan process may be stopped. The autonomous scanner may hold in an idle mode. During that mode, the patient may be guided to retake its original position via a feedback system.

Abstract: Provided is a sweat sensing device (100). The device comprises a body (102) for positioning against skin (104). A recess (108) is defined in the body for receiving sweat from a skin area. The device further comprises an optical detection assembly (114) configured to detect a discrete sweat droplet (106) protruding into the recess from a sweat pore (110) in the skin area, and a fluidic system (116) configured to transport the sweat droplet (106) away from the recess (108) following detection of the sweat droplet by the optical detection assembly (114).

Abstract: Compounds of Formula (I): pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.

Abstract: A system and method for differentiating between different modes of pulsed electrical discharges via of an amplitude to time (ATC) conversion circuit is described. A bipolar ATC circuit is used to add together the positive and negative portions of an attenuated and filtered signal derived either from the voltage or current of a pulse. Alternatively, a unipolar ATC circuit may be employed. The resulting processed signal is compared against a reference voltage to generate an output signal that is active for the amount of time that the processed signal exceeds the reference voltage. Discharge mode is determined based on three factors: did a pulse occur, if a pulse occurred when did the pulse start relative to the original pulse event, and what is the duty cycle of the pulse. Subsequent pulse generated may be controlled accordingly.

Abstract: The invention relates to a computer-implemented method (600) of monitoring patient data. A patient record data source enables to access a patient record of a patient, wherein the patient record indicates a version of a medical protocol currently being used with the patient. A protocol data source indicates available versions of the medical protocol and/or of a medical guideline from which the medical protocol is derived. The used version of the medical protocol is compared to a further version of the medical protocol or of the medical guideline accessible via the protocol data source to obtain a change indicator for the used version of the medical protocol, and the change indicator is output.

Abstract: The invention is directed to a personal care system (100) configured to allow an addition of a sensor functionality to the system (100). The system (100) comprises a data reader (102) for receiving a code (200), and a programmable controller (104). The system (100) is configured for triggering a software reconfiguration of a software associated with at least one hardware component (106) of the system (100) based on the code (200) received by the data reader (102). The programmable controller (104) is configured for changing a control of the hardware component (106) of the system (100) based on the triggered software reconfiguration. The change of the control of the hardware component (106) of the system (100) causes an addition of a sensor functionality to the hardware component (106) of the system (100).