Abstract: A compound of the formula: ##STR1## wherein R.sup.1 is lower alkyl optionally substituted aryl; or amino optionally substituted; andR.sup.2 is hydrogen or lower alkyl; orR.sup.1 and R.sup.2 are taken together with the attached nitrogen atom to form a heterocyclic group optionally substituted;R.sup.3 is hydrogen or lower alkyl; andR.sup.

Abstract: Indole derivatives of the formula ##STR1## and pharmaceutical compositions thereof. They are useful for treating or preventing testosterone 5-alpha-reductase-mediated diseases, such as alopecia, acnes and prostatism.

Abstract: A transmission line driver circuit (10) includes a signal input (12). A first capacitor (28) stores a first voltage level corresponding to a first of two possible bit values of an input signal. A second capacitor (44) stores a second voltage level corresponding to a second of the possible bit values. First and second voltage supply sources (24, 42) are selectively and respectively coupled to the first and second capacitors (28, 44) for recharging these capacitors to their respective voltage levels. A transmission line (50) is coupled to an output of a switching circuit. The switching circuit is operable to couple the first capacitor (28) to the switching circuit output (34) in response to receiving an input signal of a first bit value. The switching circuit is further operable to couple the second capacitor (44) to the output (34) in response to receiving an input signal of a second bit value. The bit value is thereby propagated onto the transmission line (50).

Abstract: The invention relates to novel intermediate compounds for preparation of novel amino acid derivatives having renin inhibiting activity.

Abstract: The invention relates to pyrrolidine derivatives having thromboxane A.sub.2 antagonism and TXA.sub.2 synthetase-inhibitory activity, of the formula ##STR1## wherein R.sup.1 is pyridyl(lower)alkyl, R.sup.2 is an acyl group selected from the group consisting of lower alkanoyl, lower alkoxycarbonyl, lower alkylsulfonyl, phenylsulfonyl, benzoyl, phenyl(lower)alkanoyl, cyclo(lower)alkyl(lower)alkanoyl, phenyl(lower)alkoxycarbonyl and phenylcarbamoyl, each of which may have 1 to 3 substituent(s) selected from the group consisting of halogen, lower alkyl, lower alkoxy, nitro and mono(or di or tri)halo(lower)alkyl, andR.sup.3 is carboxy(lower)alkyl, protected carboxy(lower)alkyl, carboxyphenyl or protected carboxyphenyl,or a pharmaceutically acceptable salt thereof.

Abstract: An expansible FIFO memory device to which additional memory stages having the same internal memory structure may be connected to form a multistage memory of increased memory storage capacity, uses a basic control circuit which is applicable to all of the added memory stages. The respective memory stages are connected in parallel such that only one memory stage is operable at one time instant in performing a data write or a data read operation. As a memory stage is completely filled with data written thereinto or conversely is completely emptied from the readout of data therefrom, the control circuit common to all of the memory stages provides appropriate signals indicative of the full condition of the memory stage in a data write operation and of the empty condition of the memory stage in a data read operation which signals are communicated to the next memory stage for activation thereof in a continuation of the data write or data read operation.

Abstract: A cooling water temperature controlling apparatus for an internal combustion engine comprises a butterfly valve placed in a cooling water passage for the internal combustion engine at a position between the inlet port of a radiator and the inlet port of a radiator bypass pipe, and a stepper motor connected to the butterfly valve through a reduction gear having a worm gear wheel so as to adjust a degree of opening of the butterfly valve depending on the temperature of cooling water.

Abstract: A disposable pressure transducer for measuring fluid pressure, which includes a sensor assembly in a housing. The housing includes a fluid chamber and a sensor-accommodating chamber which are formed integrally with each other.

Abstract: A disposable pressure transducer for measuring fluid pressure, which includes a sensor assembly in a housing. The housing includes a fluid chamber and a sensor-accommodating chamber which are formed integrally with each other.

Abstract: A memory circuit (14) having features specifically adapted to permit the memory circuit (14) to serve as a video frame memory. The memory circuit (14) contains a dynamic random access memory array (24) with buffers (18, 20) on input and output data ports (22) thereof to permit asynchronious read, write and refresh accesses to the memory array (24). The memory circuit (14) is accessed both serially and randomly. An address generator (28) contains an address buffer register (36) which stores a random access address and an address sequencer (40) which provides a stream of addresses to the memory array (24). An initial address for the stream of addresses is the random access address stored in the address buffer register (36).

Abstract: A high performance test head (18) communicates test signals between integrated circuit test pads and integrated circuit tester. Test head (18) comprises metal bumps (22) that electrically couple with test pads to communicate test signals between test pads and test circuitry. Planar foundation plate (30) provides structural support. Compliant material layer (26) associates with metal bumps (22) and compresses to assure positive contact between metal bumps (22) and test pads. Compliant material layer (26) is positioned between foundation plate (30) and metal bumps (22). Interconnection line (20) adjoins test head (18) to connect metal bumps (22) between test circuitry and integrated circuits. The present invention includes a method for high performance communication of test signals between test pads and test circuitry. The present invention further includes the method of applying semiconductor device fabrication techniques to produce a high performance test head (18).

Abstract: The invention relates to dithioacetal compounds having 5-lipoxygenase-inhibiting activity, of the formula: ##STR1## wherein R.sup.1 is lower alkyl, di-(lower)alkylamino, aryl, or heterocyclic group which may have one or more substitutents selected from halogen, lower alkyl, lower alkoxy and phenyl,R.sup.2 and R.sup.3 are each lower alkyl, aryl or ar-(lower)alkyl, or R.sup.2 and R.sup.3 are together to form 1,3-dithian ring,R.sup.4 is hydrogen or lower alkoxy, andn is 0 or an integer 1 to 4 and pharmaceutically acceptable salts thereof.

Abstract: A full wafer integrated circuit testing device (10) tests integrated circuits (15) formed as a wafer in conjunction with a test control unit (40). Probe units (14) associate with respective integrated circuits (15). Probe tips (16) on probe units (14) communicate with respective pads (19) with the integrated circuits (15). Interface circuitry (36) selectively communicates test data between the test control unit (40) and the integrated circuit (15). Test pins (16) have positions on probe units (14) associated with respective integrated circuit connection points (19) for testing associated integrated circuit (15) components. Interface circuitry (36) includes comparators (54 and 56) that compare signals between the integrated circuit (15) and the test control unit (40). Memory components (66 and 68) store data associated with signals from test control unit (40) and said integrated circuit (15).

Abstract: A signal transmission circuit (10) for transmitting a signal (V.sub.IN) between dies on a wafer. A transmission node (72) is precharged to a first voltage (70) that is representative of a first of a plurality of bit values in response to the actuation of a gate (48) of a P-channel transistor (50) by a first state control signal (.phi..sub.1). At a later time, a second state of the control signal (.phi..sub.1) actuates a pass gate transistor (38) to couple the end of a first transmission signal line segment (32) to a node (40). A preselected state of the node (40) will cause the signal node (72) to be grounded to a logic zero (74). The signal node (72) is selectively coupled to a latch (92) by a one-shot pass gate (76). The output (102) of the latch (92) is connected to the beginning end of a second transmission line segment (104). The transmission of the signal thus relies on the state of the signal node (72) rather than on the presence or absence of a connection directly to a voltage supply such as V.sub.dd.

Abstract: The invention relates to an anti-inflammatory or antiallergic composition containing a compound of the formula ##STR1## wherein A is ##STR2## R.sup.1 is aryl which may have cyano or carbamoyl, or heterocyclic group which may have lower alkyl,R.sup.2 is hydrogen or lower alkyl,R.sup.3 is lower alkyl,X is hydrogen, halogen, hydroxy or lower alkyl,m is an integer 1 or 2, andn is an integer 1 to 4, or pharmaceutically acceptable salts thereof.

Abstract: This invention relates to new carboxylic acid derivatives of the formula: ##STR1## wherein R.sup.1 is hydrogen, lower alkyl or aryl, and pharmaceutically acceptable salt thereof which inhibit activity of DHP-I, to a process for preparing them and to an antibacterial composition comprising them and carbapenem antibiotics.

Abstract: A system and method for testing the continuity of interconnecting nets on a substrate to be used in multi-chip technology is provided. The system includes coupling a test pad (15) to the net (12) to be tested. The test pad (15) is coupled through a diode (34) to a common node (32). The voltage of a first node (16) of the net (12) is sensed by a voltmeter (38) which is coupled to ground. A predetermined current signal is applied to each node (16, 18, 20, 22) in the net through the use of a probe (42). The voltage of the remaining nets (14) is sensed by a voltmeter (44). If an erroneous interconnection (31) is present between the net (12) to be tested and any other net (14) on the substrate, the voltage of the other net (14) will fluctuate. The voltmeter (38) will indicate if there is an electrical connection between the node (16) and the test pad (15) during testing.

Abstract: The invention relates to thiazepine derivatives, which are antagonists of platelet activating factor, of the formula: ##STR1## wherein R.sup.1 is ar(lower)alkyl which may have suitable substituent(s),R.sup.2 is hydrogen, lower alkyl which may have suitable substituent(s), or a group of the formula: ##STR2## in which A is lower alkylene and X is halogen, n is 0, 1 or 2 and Y is --CH.sub.2 --CH.sub.2 -- or ##STR3## or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a method of treating asthma comprising administering a compound of the formula: ##STR1## wherein A is ##STR2## R.sup.1 is quinolyl, R.sup.2 is hydrogen or lower alkyl,R.sup.3 is lower alkyl,X is hydrogen, halogen, hydroxy or lower alkyl,m is integer 1 or 2, andn is an integer 1 or 4, or pharmaceutically acceptable salts thereof.

Abstract: A compound of the formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are each lower alkyl, R.sup.4 is hydrogen or hydroxy, and a heavy solid line means a double bond when R.sup.4 is hydrogen and a single bond when R.sup.4 is hydroxy is useful in the treatment of diseases caused by reactive oxygen species and organic radicals.