Abstract: The system and method utilizes a computer system having processors that receive quantitative data from users and generate data to facilitate prioritization and reduction of barriers that prevent patients from receiving medical therapies from a particular healthcare provider in rank order. The processors provide an initial rank order of potential barriers based on calculated correlation coefficient, and determine a subsequent rank order of potential barriers based on the calculated correlation coefficient and other data indicative of the effect of each barrier on the patients. The system and method provides for a systematic, data-driven, and validated process to improve patient access to healthcare providers.

Abstract: Roll on floor (ROF) circuit breakers include a plurality of support wheels configured to contact a support surface as the ROF circuit breaker is moved between locations. The support wheels have a rocker configuration whereby weight of the ROF circuit breaker is transferred between different sets of the wheels during movement to thereby facilitate ease of movement.

Abstract: In a substrate treatment process, substrates are moved by a transporting device in a transporting direction through a substrate treatment installation having a number of chambers. The substrates are moved by transporting sections of the transporting device driven independently of one another. The transporting sections are driven such that, if substrates dwell temporarily in the transporting section, they are moved back and forth. Stresses in a substrate brought about by differing inputs of heat as a result of both process-induced and malfunction-induced dwell times of the substrate in a chamber are reduced by compensating within the chamber for a structurally brought about input of heat into the substrate, varying periodically over the length of the chamber, during temporary dwelling of the substrate in the chamber by moving the substrate back and forth over at least one period of the heat input by a change of the transporting direction.

Abstract: An accurate blending system for blending first and second liquid components includes a first feed adapted to communicate with a supply of the first component and a second feed adapted to communicate with a supply of the second component. A shear blender is in communication with the first and second feeds. A first sensor is in communication with an outlet of the shear blender. A controller is in communication with the first sensor so that a first characteristic of a solution exiting the shear blender can be detected. The controller is also in communication with the second feed so that delivery of the second component to the shear blender can be controlled based upon the detected first characteristic.

Abstract: The invention provides anti-IL-18R1 antibodies and methods of using the same.

Abstract: A method includes gathering a plurality of instances of online activity associated with a user, analyzing the plurality of instances of online activity to determine a characteristic that is likely to correspond to a profile attribute of the user and generating a profile enrichment suggestion for the user based on the determined characteristic.

Abstract: A system for regulating a pressure of a piston on a bed in a flow through column system, where the flow through column system includes a piston pressure chamber in communication with the piston and an inlet line and an outlet line in communication with the bed. A pump has an inlet in communication with a supply of hydraulic fluid. A forward pressure reference communicates with the inlet line. A forward pressure regulator has a reference inlet in communication with the forward pressure reference and an inlet in communication with the pump. A switching valve communicates with the piston pressure chamber, and also has a inlet in communication with the outlet of the forward pressure regulator. A back pressure reference communicates with the outlet line. A back pressure regulator has an inlet in communication with the outlet of the switching valve, a reference inlet in communication with the back pressure reference and an outlet in communication with the supply of hydraulic fluid.

Abstract: A mounting support for a photovoltaic module is described. The mounting support includes a foundation having an integrated wire-way ledge portion. A photovoltaic module support mechanism is coupled with the foundation.

Abstract: The present invention provides an Al—Zn—Mg—Cu casting alloy that provides high strength for automotive and aerospace applications and optimized stress corrosion cracking resistance in highly corrosive and tensile environments. The inventive alloy composition includes about 3.5 wt. % to about 5.5 wt. % Zn; about 1.0 wt. % to about 3.0 wt. % Mg; about 0.5 wt. % to about 1.2 wt. % Cu; less than about 1.0 wt. % Si; less than about 0.30 wt. % Mn; less than about 0.30 wt. % Fe; and a balance of Al and incidental impurities.

Abstract: A gaming system is disclosed wherein an outcome probability is determined for each of a number of possible outcomes achievable in a wagering game. Different subsets are then associated with each different prize level in a desired prize distribution. The possible outcomes and their respective probability are assigned or mapped to the different subsets so that the probability of achieving a possible outcome included in a subset comprises a value approximating the desired probability of an award of the prize level with which the subset is associated.

Abstract: The invention provides anti-IL-18R1 antibodies and methods of using the same.

Abstract: A processing column system includes an inlet, an outlet, a piston head and a piston pressure chamber for providing a controlled bed pressure to the piston head and thus to a substrate and/or liquid bed positioned within the column. A tracking regulator is in fluid communication with a source of pressurized hydraulic fluid and the piston pressure chamber as well as the inlet to the column. The tracking regulator receives a pressure of a process fluid flow into the processing column. The tracking regulator has a hydraulic fluid drain port in fluid communication with the source of pressurized hydraulic fluid. The tracking regulator directs hydraulic fluid from the piston pressure chamber to the source of pressurized hydraulic fluid when the tracking regulator detects a drop in the pressure of the process fluid flow. The source of pressurized hydraulic fluid provides to the tracking regulator a pressure equal to a set bed pressure of the system plus a maximum anticipated process flow pressure.

Abstract: The current invention is related to a conjugate comprising one or more antifusogenic peptides and an anti-CCR5 antibody (mAb CCR5) characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of said anti-CCR5 antibody and to the pharmaceutical use of said conjugate.

Abstract: The current invention is related to a conjugate comprising one or more antifusogenic peptides and an anti-CCR5 antibody (mAb CCR5) characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of the anti-CCR5 antibody and to the pharmaceutical use of the conjugate.

Abstract: The present invention provides a conjugate consisting essentially of a NK4 molecule and a polyethylene glycol group having a molecular weight of from about 20 to about 40 kDa. The invention also provides a composition in which the monoPEGylated conjugates comprise at least 90% of the total of pegylated NK4 molecules and unpegylated NK4 molecules in the composition. Also provided is a composition in which the monoPEGylated conjugates comprise conjugates in which the PEG groups are attached to groups randomly selected from the lysine side chains of NK4 molecules and the N-terminal amino groups of NK4 molecules. A method for the treatment of cancer by administering 1 to 30 mg monoPEGylated NK4 per kg per day is further provided.

Abstract: A gaming system is disclosed wherein an outcome probability is determined for each of a number of possible outcomes achievable in a wagering game. Different subsets are then associated with each different prize level in a desired prize distribution. The possible outcomes and their respective probability are assigned or mapped to the different subsets so that the probability of achieving a possible outcome included in a subset comprises a value approximating the desired probability of an award of the prize level with which the subset is associated.

Abstract: A mounting support for a photovoltaic module is described. The mounting support includes a foundation having an integrated wire-way ledge portion. A photovoltaic module support mechanism is coupled with the foundation.

Abstract: The invention relates to a packaging machine for packing food products in a plastic packaging, said machine comprising a device for applying a transponder to the plastic packaging, and a system for data exchange between the transponder and a computer unit and/or a regulating unit, by which means data can be transmitted to the transponder or called therefrom.

Abstract: Antibodies that specifically bind to CCR5 are useful for treating immunosuppressive disease.

Abstract: An antibody binding to CCR5 and being glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is 65% or lower has improved properties in anti-inflammatory therapy.