Abstract: Disclosed herein is an efficient, economical, industrially advantageous, straight-through process for the preparation of cyclic amides, also referred as lactams, in substantially pure form and high yield, from the corresponding cyclic ketones and a hydroxylammonium salt, using a combination of amphoteric metal oxide or amphoteric masked metal oxide and a base.

Abstract: A system and method that provides a proximity sensor disposed within a door handle of a vehicle to enable one or more commands to be transmitted to the vehicle by a user's hand, wherein the door handle is in a harsh outdoor environment such that the door handle may be wet when the proximity sensor is used to detect the touch or presence of a user's hand, and wherein the proximity sensor is able to compensate for the presence of the water and enable reliable operation of the proximity sensor and thereby enable commands to be sent to the vehicle.

Abstract: A device and method are provided for supplying a medium to an object of interest, such as a patient to be scanned for image acquisition. The device comprises an arc-shaped member and a support for said arc-shaped member, wherein the arc-shaped member is configured to support a radiation source on one end and a detector on another end to scan the object of interest, and the support comprises a gantry with a rotatable support arm supporting the arc-shaped member. The device further comprises at least one medium supply unit mounted on the gantry. The supply unit is connectable to a cable that is guided in the vicinity or in the region of the axis of rotation of the support arm so that the object of interest can be supplied with a perfusion or any other medium, while enabling the mobile imaging device to rotate around the patient to acquire x-ray images.

Abstract: The present invention relates to compounds of Formula I, a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).

Abstract: The present invention relates to isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.

Abstract: Example systems and methods are disclosed for determining the direction of an actor based on image data and sensors in an environment. The method may include receiving point cloud data for an actor at a location within the environment. The method may also include receiving image data of the location. The received image data corresponds to the point cloud data received from the same location. The method may also include identifying a part of the received image data that is representative of the face of the actor. The method may further include determining a direction of the face of the actor based on the identified part of the received image data. The method may further include determining a direction of the actor based on the direction of the face of the actor. The method may also include providing information indicating the determined direction of the actor.

Abstract: A system and method for enabling arbitrary mapping of any number, shape and size of controls or features of a physical input device to a virtual reality device that is used in a virtual reality or augmented reality environment.

Abstract: Disclosed herein is an efficient, economical, industrially advantageous, straight-through process for the preparation of cyclic amides, also referred as lactams, in substantially pure form and high yield, from the corresponding cyclic ketones and a hydroxylammonium salt, using a combination of amphoteric metal oxide or amphoteric masked metal oxide and a base.

Abstract: The automotive industry is growing rapidly and requires a more effective system to manage customer vehicles within automotive organizations. The automotive identification tag system utilizes the vital elements of tracking a customer's vehicle and information in a simple and effective manner. The tag system is to serve the purpose of coordinating an assigned reference designation to a vehicle with number(s), letter(s) or symbol(s) in a corresponding sequence to identify the specified vehicle through the inclusive tag system. The inclusive tag has detachable elements that consist of multiple elements such as mirror tag, key tag and claim check tag. The mirror tag is a highly visible element to be displayed on a vehicle's rear view mirror. The key tag requires attachment to a key ring. The claim tag is for the customer tracking purposes. Each specified tag is detachable by means of perforations along each boarding tag.

Abstract: The present application pertains to a braided dual-sided compression packing seal, methods for producing and using such a seal, and apparatuses suitable for producing such a seal. The braided dual-sided compression packing seal is made up of two or more different materials that are braided together in such a way that, in cross-section, the compression packing seal has an asymmetrical configuration relative to a first axis that is substantially perpendicular to the longitudinal axis and is substantially perpendicular to a side of the compression packing seal. Accordingly, when viewed in a cross-sectional plane, the compression packing seal may expose substantially only a first material along a first side of the seal, and substantially only a second material along a second side of the seal.

Abstract: A lubricious coating for use on an implantable medical device includes a heterochelic component, a homotelechelic polymer and biocompatible initiator. Methods of forming such lubricious coatings are also provided.

Abstract: The present invention relates to the synthesis of alkoxy substituted benzaldehydes obtained from the corresponding alkoxy substituted benzenes. Alkoxy substituted benzaldehydes are products of broad commercial interest and are used as end products and intermediates in flavor and fragrance applications and pharmaceutical ingredients. For example, 3,4-methylendioxy-benzaldehyde (also known as heliotropin or piperonal) is used widely both as a end product and intermediate for the above mentioned applications. Other examples include 3,4-dimethoxybenzaldehyde, 3,4,5-trimethoxybenzaldehyde and 3,4-ethylenedioxybenzene which are intermediates in the synthesis of active pharmaceutical intermediates.

Abstract: A system and method for providing a virtual reality game controller with improved functionality by providing capacitive touch and proximity sensors on the controller to enable additional feedback to the user such that interaction with a physical object such as a game controller may be translated into interaction with a virtual tool in a virtual environment such as providing a visual indication in the virtual environment that a finger or thumb is approaching a button of a physical game controller.

Abstract: The present application pertains to a braided dual-sided compression packing seal, methods for producing and using such a seal, and apparatuses suitable for producing such a seal. The braided dual-sided compression packing seal is made up of two or more different materials that are braided together in such a way that, in cross-section, the compression packing seal has an asymmetrical configuration relative to a first axis that is substantially perpendicular to the longitudinal axis and is substantially perpendicular to a side of the compression packing seal. Accordingly, when viewed in a cross-sectional plane, the compression packing seal may expose substantially only a first material along a first side of the seal, and substantially only a second material along a second side of the seal.

Abstract: The present invention provides compounds of formula (I) as described herein and pharmaceutically acceptable salts, hydrates and solvates thereof for use in medicine, for example in the treatment of acute myeloid leukaemia:

Abstract: The present invention relates to compounds of Formula I, a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).

Abstract: Example systems and methods are disclosed for determining the direction of an actor based on image data and sensors in an environment. The method may include receiving point cloud data for an actor at a location within the environment. The method may also include receiving image data of the location. The received image data corresponds to the point cloud data received from the same location. The method may also include identifying a part of the received image data that is representative of the face of the actor. The method may further include determining a direction of the face of the actor based on the identified part of the received image data. The method may further include determining a direction of the actor based on the direction of the face of the actor. The method may also include providing information indicating the determined direction of the actor.

Abstract: Example systems and methods are disclosed for determining the direction of an actor based on image data and sensors in an environment. The method may include receiving point cloud data for an actor at a location within the environment. The method may also include receiving image data of the location. The received image data corresponds to the point cloud data received from the same location. The method may also include identifying a part of the received image data that is representative of the face of the actor. The method may further include determining a direction of the face of the actor based on the identified part of the received image data. The method may further include determining a direction of the actor based on the direction of the face of the actor. The method may also include providing information indicating the determined direction of the actor.

Abstract: The present invention relates to compounds of Formula I, a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).