Abstract: A nutritionally complete infant formula containing sialic acid derived from one or a number of nutritionally appropriate sources is described.

Abstract: A process of priming mature, imbibed, germinated somatic embryos of a conifer species. The process comprises fully immersing mature, imbibed, germinated somatic conifer embryos in a sterile liquid nutrient medium, bubbling an oxygen-containing gas through the liquid nutrient medium containing the germinants to form an aerated embryo-containing nutrient medium, optionally exposing the aerated germinant-containing nutrient medium to light, at least intermittently, continuing the immersion, bubbling and optional exposure to light for a period of time effective to produce at least some successfully primed conifer germinants that are adapted for subsequent planting and conversion to viable seedlings, and removing the successfully primed conifer germinants from the nutrient medium.

Abstract: This invention relates to a novel 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidinyl derivative and its use in the manufacture of pharmaceutical compositions. The compound of the invention is found to be a cholinergic ligand at the nicotinic acetylcholine receptors. Due to its pharmacological profile the compound of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.

Abstract: Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.

Abstract: The present invention relates to compounds of the Formula I, wherein G, A, X1, X2, X3, Z, E, Y, and X are defined herein. The compounds modulate protein kinase enzymatic activity to modulate cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Raf. Methods of using and preparing the compounds, and pharmaceutical compositions thereof, to treat kinase-dependent diseases and conditions are also an aspect of the invention.

Abstract: This invention relates to novel 8,10-diaza-bicyclo[4.3.1]decane derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.

Abstract: Methods of and equipment for converting existing standard motion picture theatres to one having highly immersive, large fields of view are addressed. Aspects of the methods including moving motion picture screens closer to the audience and employing different projection equipment to avoid or minimize appearance of unrealistic or non-natural image artifacts. Alternative sound systems too are detailed.

Abstract: The invention provides a nutrient medium useful for sowing a somatic plant embryo or germinant of conifer species, which comprises particles of a solid component present within a flowable or semi-solid component containing water and a carbohydrate nutrient for the embryos or germinants. The nutrient medium has a fluidity such that at least some of the flowable or semi-solid component containing the carbohydrate nutrient remains in contact with the embryos or germinant at least until the embryo or germinant establishes vigorous growth under environmental conditions effective for such growth. The particles of the solid component are adapted to remain in contact with the embryo or germinant after of the flowable or semi-solid material dissipates, thereby providing continuing physical support for the embryo or germinant after the dissipation.

Abstract: The present invention is directed to a test probe having an indexable probe tip. In one embodiment, an insulative sleeve extends from the test probe and surrounds a portion of the exposed probe tip. The insulative sleeve is moveable relative to the probe tip and may be indexable to at least two positions. For instance, the insulative sleeve locks into a first position to provide a first length of the probe tip exposed from the insulative sleeve, and the insulative sleeve locks into a second position to provide a second length of the probe tip exposed from the insulative sleeve.

Abstract: One or more complex lipids including gangliosides to achieve particular health benefits including maintaining or increasing cognitive development or maintaining or increasing growth in a foetal, infant or child subject.

Abstract: Embodiments described herein include generating a navigable medical history corresponding to a patient. Reference information related to medical records for the patient is stored in a referenced records database based on a standardized healthcare code in the medical records. The reference information is inserted into the referenced records database by the medical history system. The medical history system generates the navigable medical history associated with the patient based on the reference information.

Abstract: A nutritionally complete infant formula containing sialic acid derived from one or a number of nutritionally appropriate sources is described.

Abstract: A prefabricated wall panel has a top frame structure defining an upward-opening channel extending lengthwise along the upper edge of the panel. An elongate header member is normally disposed within this channel. The header member is vertically slidably supported on supports fixed to the top frame structure so that the header member, in a storage position, is retained in the space. When the panel has been swung upwardly so that the upper edge is aligned below a preinstalled ceiling track, then the header member is manually displaced upwardly until the header telescopes over the ceiling track. A fixed connection is then formed between the header and the ceiling track to provide lateral stability at the upper edge of the wall panel.

Abstract: The present invention relates to systems, methods, data structures and user interfaces for generating and presenting information as to how and why the book yield of an investment portfolio changed over a time interval. Dynamic book yield analysis is particularly useful for bond portfolio analysis and management. Transactions and events that occur in a financial market during a pre-specified time period and relating to a portfolio of assets are identified by a computer server. Specifically, the book yields and book values for these transactions and events are accessed from the portfolio accounting system and the data for each transaction/event are categorized according to transaction/event type (though net cash equivalents are first separated out into their own category). The categorized information is then stored in a data structure residing on the system.

Abstract: This invention relates to novel 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their use in the manufacture of pharmaceutical compositions. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.

Abstract: The present invention relates to compounds of the Formula I, wherein G, A, X1, X2, X3, Z, E, Y, and X are defined herein. The compounds modulate protein kinase enzymatic activity to modulate cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Raf. Methods of using and preparing the compounds, and pharmaceutical compositions thereof, to treat kinase-dependent diseases and conditions are also an aspect of the invention.

Abstract: A method of performing a scanning sequence for an ultrasound scan includes establishing a number of ultrasound beams to be transmitted during an ultrasound scan, establishing a pulse repetition interval to be used for performing the ultrasound scan, and establishing a number of firings of each of the ultrasound beams to be performed during the ultrasound scan. The method further includes performing a scanning sequence based on a processing of one or more parameters selected from the group consisting of the number of ultrasound beams, the pulse repetition interval, and the number of firings of the ultrasound beams, wherein the processing of the one or more parameters is configured to provide a continuous interleaving in the transmitted beams thereby avoiding a generation of beam interleaving discontinuities and a formation of artifacts in a resulting image.

Abstract: The invention is directed to Compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as well as methods of making and using the compounds.

Abstract: An adaptive use of recessed lights cans for retrofitting various types of light fixtures. For example, a recessed light could be retrofitted as a junction box. In other embodiments, the recessed light could supply power for a speaker that includes a threaded power. Other electronic devices are contemplated that could be installed in a recessed light housing, including a battery backup light, a wireless repeater, a surveillance camera, a cellular phone booster, an infrared repeater, a fan, a wireless perimeter barrier, an alarm system, a sound machine, a web cam, an electronic pest control, a smoke detector, a carbon monoxide detector, an air purifier, a HVAC repeater control, a temperature monitor, a humidity monitor, a sound monitor, a photoelectric motion detector light, a photoelectric light sensor, and a hanging mobile.

Abstract: A method of sowing a somatic plant embryo or germinant of a conifer species to facilitate subsequent development of the embryo or germinant into an autotrophic seedling. The method involves the following steps carried out ex vitro in non-sterile conditions: providing a nutrient medium comprising particles of a solid component present within a flowable or semi-solid component containing water and a carbohydrate nutrient for the embryo or germinant, dispensing a quantity of the nutrient medium onto a surface of a porous solid growth substrate for the somatic plant embryo or germinant, to and contacting the plant embryo or germinant with the nutrient medium. The nutrient medium has a fluidity such that at least some of the flowable or semi-solid component containing the carbohydrate nutrient remains in contact with the embryo or germinant at least until the embryo or germinant establishes vigorous growth under environmental conditions effective for such growth.