Patents by Inventor Syed A. Ali

Syed A. Ali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for the treatment of cancer
    Patent number: 8513292
    Abstract: The present invention relates to pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound or pyrrolidine-2,5-dione compound of the present invention.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: August 20, 2013
    Assignee: ArQule, Inc.
    Inventors: Neil Westlund, Jason Hill, Mark A. Ashwell, Nivedita Namdev, Jianqiang Wang, Syed Ali
  • Compositions and methods for treating cancer by inhibiting the secretion of microparticles
    Patent number: 8476237
    Abstract: Novel peptides that inhibit the release of microparticles from cells are disclosed. Also disclosed are polynucleotides encoding the peptides, expression vectors carrying the polynucleotides and methods for treating tumors using the novel peptides.
    Type: Grant
    Filed: September 17, 2012
    Date of Patent: July 2, 2013
    Assignee: Morehouse School of Medicine
    Inventors: Vincent Craig Bond, Michael Powell, Ming Bo Huang, Syed Ali, Andrea D. Raymond, Martin Neville Shelton, Francois Jean Villinger
  • COMPOSITIONS AND METHODS FOR EXOSOME TARGETED EXPRESSION
    Publication number: 20130156801
    Abstract: The present application relates to methods of producing exosomes. The application also provides a method for preparing a protein composition comprising culturing an exosome-producing cell expressing a Nef-fusion protein comprising a Nef-derived peptide fused to a protein of interest; isolating exosomes from the exosome-producing cell culture; and purifying the protein of interest from the isolated exosomes. The application further discloses compositions that comprise exosomes containing the Nef-fusion protein, as well as methods of using the Nef-fusion protein and exosomes containing the Nef-fusion protein.
    Type: Application
    Filed: December 15, 2011
    Publication date: June 20, 2013
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Vincent Craig BOND, Michael POWELL, Ming Bo HUANG, Syed ALI
  • SCENE DEPENDENT MOTION SEARCH RANGE ADAPTATION
    Publication number: 20130107960
    Abstract: Techniques are disclosed relating to scene dependent motion search range adaptation. A search range for a next frame of a video may be modified based on statistical information. Statistical information may include sizes of motion vectors for the current frame. In some embodiments, statistical information may include a histogram with each point on the histogram representing a motion vector size frequency based on the current frame motion vectors. The distribution of the histogram may be used to determine a ratio that may be used to modify the search range for the next frame.
    Type: Application
    Filed: November 2, 2011
    Publication date: May 2, 2013
    Inventor: Syed Ali
  • Continuous downhole scale monitoring and inhibition system
    Patent number: 8430162
    Abstract: A technique facilitates monitoring of conditions which are prone to cause scale precipitation around downhole equipment. The technique also enables a local, downhole reaction to the potential for precipitation of scale. A downhole scale monitoring and inhibition system may be provided with a measurement module and injection module. The measurement module monitors at least one downhole parameter indicative of the potential for scale formation. In response to data output from the measurement module, the injection module is operated to provide downhole, local injections of an inhibitor chemical.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: April 30, 2013
    Assignee: Schlumberger Technology Corporation
    Inventors: Spyro Kotsonis, Syed A. Ali, Ives Loretz
  • Compositions and methods for treating aids or cancer by inhibiting the secretion of microparticles
    Patent number: 8431530
    Abstract: Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.
    Type: Grant
    Filed: May 20, 2010
    Date of Patent: April 30, 2013
    Assignee: Morehouse School of Medicine
    Inventors: Vincent Craig Bond, Michael Powell, Ming Bo Huang, Syed Ali, Andrea D. Raymond, Martin Neville Shelton, Francois Jean Villinger
  • ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20130089525
    Abstract: The present application discloses a method for treating microbial infection using an antimicrobial composition comprises antimicrobial peptide which contains at least one VGFPV motif.
    Type: Application
    Filed: October 7, 2011
    Publication date: April 11, 2013
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Vincent Craig Bond, Michael Powell, Ming Bo Huang, Syed Ali, Martin Neville Shelton
  • Polysaccharide treatment fluid and method of treating a subterranean formation
    Patent number: 8367589
    Abstract: A treatment fluid for treating a subterranean formation penetrated by a wellbore is formed from an aqueous medium, a diutan heteropolysaccharide having a tetrasaccharide repeating unit in the polymer backbone and a peroxide breaker. A method of treating a subterranean formation penetrated by a wellbore may be carried out by introducing the treatment fluid into the formation through the wellbore. Breaking aids or catalysts may also be used with the treatment fluid.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: February 5, 2013
    Assignee: Schlumberger Technology Corporation
    Inventors: Leiming Li, Syed Ali, Oscar Bustos, Lijun Lin, Curtis L. Boney
  • Substituted 5,6-dihydro-6-phenylbenzo[F]isoquinolin-2-amine compounds
    Patent number: 8357694
    Abstract: The present invention relates to substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: January 22, 2013
    Assignee: ArQule, Inc.
    Inventors: Syed Ali, Mark Ashwell, Manish Tandon, Nivedita Namdev, Jean-Marc Lapierre, Neil Westlund, Rocio Palma, Rui-Yang Yang, Yanbin Liu, David Vensel, Sudharshan Eathiraj, Hui Wu, Eugene Kelleher
  • COMPOSITIONS AND METHODS FOR TREATING AIDS OR CANCER BY INHIBITING THE SECRETION OF MICROPARTICLES
    Publication number: 20130018003
    Abstract: Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.
    Type: Application
    Filed: September 17, 2012
    Publication date: January 17, 2013
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Vincent Craig Bond, Michael Powell, Ming Bo Huang, Syed Ali, Andrea D. Raymond, Martin Neville Shelton, Francois Jean Villinger
  • COMPOSITIONS AND METHODS FOR TREATING AIDS OR CANCER BY INHIBITING THE SECRETION OF MICROPARTICLES
    Publication number: 20130018002
    Abstract: Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.
    Type: Application
    Filed: September 17, 2012
    Publication date: January 17, 2013
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Vincent Craig Bond, Michael Powell, Ming Bo Huang, Syed Ali, Andrea D. Raymond, Martin Neville Shelton, Francois Jean Villinger
  • Monoconductor data-power transmission
    Patent number: 8339276
    Abstract: Apparatus and systems, as well as methods, operate to acquire downhole data associated with a borehole casing, process a portion of the downhole data at a downhole location to provide processed data, and regulate surface motor power received at a motor downhole. The surface motor power is filtered and the processed data is transmitted to a surface location on a monoconductor that also carries the surface motor power. Additional apparatus, systems, and methods are disclosed.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: December 25, 2012
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Batakrishna Mandal, Clovis Bonavides, Carl Dodge, Syed Ali, Alberto Quintero
  • Multiple zeolite catalyst
    Patent number: 8329973
    Abstract: The multiple zeolite catalyst is a catalytic composition used to convert C9+ alkylaromatic hydrocarbons to BTX, particularly commercially valuable xylenes. The catalyst is formed by mixing at least two zeolites selected from mordenite, beta zeolite, ZSM-5, ZSM-11, ZSM-12, ZSM-22, ZSM-23, MFI topology zeolite, NES topology zeolite, EU-1, MAPO-36, SAPO-5, SAPO-11, SAPO-34, and SAPO-41, and adding at least one metal component selected from Group VIB and Group VIII of the Periodic Table of the Elements. The two zeolites should have different physical and chemical characteristics, such as pore size and acidity. An exemplary catalyst includes mordenite, ZSM-5, and 3 wt. % molybdenum. The transalkylation reaction may be conducted in one or more reactors with a fixed bed, moving bed, or radial flow reactor at 200-540° C., a pressure of 1.0-5.0 MPa, and liquid hourly space velocity of 1.0-5.0 per hour.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: December 11, 2012
    Assignees: King Fahd University of Petroleum and Minerals, Japan Cooperation Center, Petroleum (JCCP)
    Inventors: Tomoyuki Inui, Masayuki Inui, legal representative, Mohammad A. Ali, Muhammad A. Al-Saleh, Syed A. Ali, Khalid Al-Nawad, Tsutomo Okamoto, Katsuhiko Ishikawa, Minoru Hatayama
  • SELECTIVE FLUID WITH ANCHORING AGENT FOR WATER CONTROL
    Publication number: 20120241156
    Abstract: Methods and apparatus for using a fluid within a subterranean formation including forming a fluid comprising an oil-soluble resin acid and an organosilicon compound and introducing the fluid to the formation, wherein the relative permeability of the formation increases, and wherein the production of water is reduced more than if no fluid was introduced to the formation. Methods and apparatus for reducing water production within a subterranean formation including forming a fluid comprising an oil-soluble resin acid and an organosilicon compound and introducing the fluid to the formation, wherein the production of water is reduced more than if no fluid was introduced to the formation.
    Type: Application
    Filed: March 23, 2011
    Publication date: September 27, 2012
    Inventors: Sumitra Mukhopadhyay, Syed A. Ali
  • COMPOSITIONS AND METHODS FOR CLEANING A WELLBORE PRIOR TO CEMENTING
    Publication number: 20120241155
    Abstract: Wellbore-cleaning compositions comprising microemulsions are useful during cementing operations. The microemulsion solvent may be selected from the group comprising methyl esters and ethoxylated alcohols. The microemulsion surfactants comprise a water-wetting surfactant, a cleaning surfactant, an emulsifying surfactant, a non-ionic surfactant and a non-ionic co-surfactant. The wellbore-cleaning compositions may be pumped alone, ahead of a conventional spacer fluid or scavenger slurry and behind a conventional spacer fluid or scavenger slurry. In addition, the wellbore-cleaning composition may be incorporated into a carrier fluid such as (but not limited to) a conventional spacer fluid or scavenger slurry. The resulting fluid mixture may be pumped as a spacer fluid.
    Type: Application
    Filed: March 25, 2011
    Publication date: September 27, 2012
    Inventors: Syed Ali, Juan Carrasquilla, Bruno Drochon
  • COATED PROPPANTS
    Publication number: 20120227967
    Abstract: Particles are provided in which proppant and gravel used in treating subterranean wellbores are coated with most or all of the chemical components needed to make the carrier fluids used to deliver them. The components come off the proppant or gravel during injection and viscosify the fluid. Components may be applied in layers, as uniform or non-uniform mixtures, or both. Particle coatings may include gas pockets that reduce the particle density.
    Type: Application
    Filed: March 10, 2011
    Publication date: September 13, 2012
    Applicant: Schlumberger Technology Corporation
    Inventors: Humair Shaikh, Syed A. Ali, Mathew Samuel
  • Method and system for pulse charging an automotive battery
    Patent number: 8264207
    Abstract: A pulse charging profile for a vehicle battery is synchronized with driver or vehicle demanded current disturbances by phase tracking the fundamental frequency of the desired pulse charging profile to those driver or vehicle demanded current disturbances. When these driver or vehicle demanded disturbances are not active, the tracked charging profile is honored.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: September 11, 2012
    Assignee: Ford Global Technologies, LLC
    Inventors: Deepak Aswani, Robert K. Taenaka, Stephen J. Hunter, Mukunda V. Prema, Syed Ali, Shailesh Patel
  • Acidic viscosity enhancer for viscoelastic surfactant fluids
    Patent number: 8247355
    Abstract: The invention discloses method of treating a subterranean formation of a well bore, the method comprising: providing a treatment fluid comprising: an aqueous base fluid; a viscosity enhancer; and a viscoelastic surfactant, wherein the enhancer is acid in the aqueous base fluid and co-operates with the viscoelastic surfactant to enhance viscosity compared to viscoelastic surfactant alone in the aqueous base fluid; and introducing the treatment fluid into the well bore.
    Type: Grant
    Filed: June 25, 2009
    Date of Patent: August 21, 2012
    Assignee: Schlumberger Technology Corporation
    Inventors: Leiming Li, Lijun Lin, Mathew M. Samuel, Syed Ali, Paul R. Howard
  • APPLICATION OF DEGRADABLE FIBERS IN INVERT EMULSION FLUIDS FOR FLUID LOSS CONTROL
    Publication number: 20120202717
    Abstract: A method of treating a subterranean formation including emplacing in a wellbore a fluid, comprising an oleaginous continuous phase, a non-oleaginous discontinuous phase, an emulsifier, at least one degradable material, and at least one bridging material, and contacting the formation with the fluid. A method and apparatus related to an invert emulsion fluid loss pill including an oleaginous continuous phase, a non-oleaginous discontinuous phase, an emulsifier, at least one degradable material, wherein the degradable material hydrolyzes to release an organic acid, and at least one bridging material.
    Type: Application
    Filed: April 20, 2012
    Publication date: August 9, 2012
    Applicants: MI L.L.C., SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: Oscar Bustos, Chau Nguyen, Syed Ali
  • Composition and method for slickwater application
    Patent number: 8211835
    Abstract: The invention provides an environmentally friendly composition including a friction reducer, a biocide, a scale inhibitor, and optionally a clay stabilizer.
    Type: Grant
    Filed: September 21, 2010
    Date of Patent: July 3, 2012
    Assignee: Schlumberger Technology Corporation
    Inventors: Paul R. Howard, Curtis L. Boney, Shawn McCleskey Rimassa, Syed A. Ali