Patents by Inventor Tong Zhang

Tong Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10590165
    Abstract: There is disclosed a Dolastatin derivative, conjugated to an antibody, comprising a Dolastatin derivative moiety of Formula IV.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: March 17, 2020
    Assignee: Sorrento Therapeutics, Inc.
    Inventors: Zhenwei Miao, Gang Chen, Tong Zhu, Alisher B. Khasanov, Dylan Deng, Hong Zhang
  • Publication number: 20200084730
    Abstract: An indication information sending method includes that a base station generates first indication information, and send the first indication information to a terminal device; and where the first indication information is used to indicate a power control manner of a first channel, the power control manner of the first channel is one power control manner in a power control manner set, and the power control manner set comprises a transmit power of a signal on the first channel is determined by a terminal device based on a first parameter; or a transmit power of a signal on the first channel is determined by a terminal device according to a rule predefined on the terminal device.
    Type: Application
    Filed: November 17, 2019
    Publication date: March 12, 2020
    Applicant: HUAWEI TECHNOLOGIES CO.,LTD.
    Inventors: Tong Ji, Zhe Jin, Weiliang Zhang
  • Publication number: 20200081982
    Abstract: A translation model based training method is provided for a computer device. The method includes inputting a source sentence to a translation model, to obtain a target sentence outputted by the translation model; determining a fidelity of the target sentence to the source sentence; using the target sentence and a reference sentence as input of a discriminator model, using the fidelity as output of the discriminator model, and training the discriminator model on a performance of calculating a similarity between the target sentence and the reference sentence; outputting the similarity by using the discriminator model; and using the source sentence as input of the translation model, using the target sentence as output of the translation model, and using the similarity as a weight coefficient, and training the translation model on a performance of outputting the corresponding target sentence according to the input source sentence.
    Type: Application
    Filed: November 15, 2019
    Publication date: March 12, 2020
    Inventors: Zhaopeng TU, Xiang KONG, Shuming SHI, Tong ZHANG
  • Patent number: 10585441
    Abstract: An aerial system and method of operating an aerial system is provided. The aerial system includes a body, a lift mechanism, a processing system, a camera, and a sensor module. The lift mechanism is coupled to the body and configured to controllably provide lift and/or thrust. The processing system is configured to control the lift mechanism to provide flight to the aerial system. The camera is coupled to the body and is configured to obtain images of an environment proximate the aerial system. The sensor module is coupled to the body and includes an emitter and a receiver. The receiver is configured to sense data related to an ambient environment associated with the aerial system. The processing system controls a controllable parameter of the lift mechanism or the emitter as a function of the sensed data.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: March 10, 2020
    Assignee: Hangzhou Zero Zero Technology Co., Ltd.
    Inventors: Yusen Qin, Tong Zhang, Mengqiu Wang
  • Publication number: 20200069666
    Abstract: Disclosed herein is a pharmaceutical combination for use in the prevention, delay of progression or treatment of cancer, wherein the pharmaceutical combination exhibits a synergistic efficacy. The pharmaceutical combination comprises a humanized antagonist monoclonal antibody against PD- and a RAF inhibitor. Also disclosed herein is a combination for use in the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject a therapeutically effective amount of a humanized antagonist monoclonal antibody against PD-1 and a therapeutically effective amount of a RAF inhibitor.
    Type: Application
    Filed: June 14, 2017
    Publication date: March 5, 2020
    Inventors: Jing SONG, Lai WANG, Kang Li, Tong ZHANG, Lusong LUO, Min WEI, Zhiyu TANG, Guoliang ZHANG, Changyou ZHOU
  • Publication number: 20200073387
    Abstract: A method for controlling an aerial system with a rotor enclosed by a housing, including: operating the rotor in a flight mode, detecting a grab event indicative of the aerial system being grabbed, and automatically operating the rotor in a standby mode. A method for controlling an aerial system including a central axis extending normal to a lateral plane of the aerial system, including: generating a first aerodynamic force with a set of rotors enclosed by a housing, detecting that an acute angle between the central axis and a gravity vector is greater than a threshold angle, and operating each rotor of the set of rotors to cooperatively generate a second aerodynamic force less than the first aerodynamic force with the set of rotors.
    Type: Application
    Filed: October 31, 2019
    Publication date: March 5, 2020
    Inventors: Mengqiu Wang, Lixin Liu, Pengxiang Jin, Jia Lu, Tong Zhang
  • Patent number: 10579539
    Abstract: A system, method and program product for exploiting in-storage transparent compression. A storage infrastructure is disclosed that includes: a storage device having physical block address (PBA) storage of a defined capacity, a transparent compression system that compresses data written to the PBA storage, and a logical block address-to-physical block address mapping table; and a host having a memory management system that includes: an initialization system that allocates an amount of logical block address (LBA) storage for the host having a capacity greater than the defined capacity of the PBA storage, and that creates a dummy file that consumes LBA storage without consuming any PBA storage; a system that gathers current PBA and LBA usage information.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: March 3, 2020
    Assignee: SCALEFLUX, INC.
    Inventors: Tong Zhang, Yang Liu, Fei Sun, Hao Zhong
  • Publication number: 20200068526
    Abstract: The signal sending method includes: generating, by a network device, a first indication signal, where the first indication signal is used to indicate that a terminal device is not paged and/or no system message changes, the first indication signal corresponds to a first international mobile subscriber identity IMSI set, and a quantity of IMSIs in the first IMSI set is less than or equal to a quantity of IMSIs corresponding to one paging occasion PO; and sending, by the network device, the first indication signal to a first terminal device, where the first terminal device is a terminal device corresponding to any IMSI in the first IMSI set.
    Type: Application
    Filed: November 4, 2019
    Publication date: February 27, 2020
    Inventors: Tong JI, Yuwan SU, Xiaolei TIE, Zhe JIN, Weiliang ZHANG
  • Patent number: 10568133
    Abstract: Embodiments of the present application disclose a random access method, a base station, and a terminal device. The terminal device receives random access configuration information from a base station, and determines a random access channel, a base frequency, and at least two frequency hopping intervals according to the random access configuration information. The terminal device sends, over the random access channel, random access signals to the base station using frequencies determined according to the base frequency and the N frequency hopping intervals. The terminal device may send the random access signals over the random access channel to the base station according to the base frequency the frequency hopping intervals and a frequency hopping pattern.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: February 18, 2020
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Zhe Chen, Sha Ma, Yiling Wu, Weiliang Zhang, Tong Ji
  • Publication number: 20200049035
    Abstract: A lubrication system includes an engine oil pump, a lubricating oil tank, a breathing pipe, a machine body, and an oil pan. The engine oil pump is formed by superposing upper and lower layers being a lubricating pump and an oil return pump. An oil inlet of the oil return pump leads to a cavity of the oil pan, and an oil outlet leads to an interior of the lubricating oil tank. An oil inlet of the lubricating pump leads to the interior of the lubricating oil tank, and an oil outlet leads to a machine filter. The machine filter is communicated with a main oil path of the machine body. An oil tank cover of the lubricating oil tank is provided with a breathing one-way valve and an oil filling port. The breathing one-way valve communicates one end of the breathing pipe, and the other end thereof communicates a crankcase.
    Type: Application
    Filed: December 1, 2017
    Publication date: February 13, 2020
    Applicant: JIANGSU UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Xuedong FENG, Youlin LING, Jian ZHANG, Wenxian TANG, Anlong SUN, Xujin HUANG, Zhongchen LIANG, Wei ZANG, Qiang LI, Tong CHEN, Jun SHI, Dongsheng LIANG, Ping HU, Yongjun FENG, Cheng CHEN
  • Patent number: 10555930
    Abstract: This present invention relates to a complex of a glucopyranosyl derivative and L-pyroglutamic acid as a sodium dependent glucose cotransporter (SGLT) inhibitor, and preparation processes thereof, and a pharmaceutical composition containing the complex, and their uses in the manufacture of a medicament for treating diabetes and/or diabetes-related diseases.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: February 11, 2020
    Assignee: NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Pengcho Tang, Zheng Gu, Wuyong Wu, Zongyuan Zhang, Panpan Kang, Tong Qu
  • Patent number: 10556952
    Abstract: The invention provides antibody heavy chain constant regions with a hinge region modified to reduce binding to Fc? receptors. The modification occurs within positions 233-236 by replacement of natural residues by glycine(s) and/or deletion(s). Such modifications can reduce binding of an antibody bearing such a constant region to Fc? receptors to background levels. The constant regions can be incorporated into any format of antibody or Fc fusion protein. Such antibodies or fusion proteins can be used in methods of treatment, particularly those in which the mechanisms of action of the antibody or Fc fusion protein is not primarily or at all dependent on effector functions, as is the case when an antibody inhibits a receptor-ligand interaction or agonizes a receptor.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: February 11, 2020
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Samuel Davis, Eric Smith, Tong Zhang, Supriya Patel
  • Publication number: 20200045451
    Abstract: The present disclosure provides a speaker, comprising a basin frame with a receiving space, a vibration system disposed at the basin frame, and a magnetic circuit system configured for driving the vibration system to generate sounds by vibration, the vibration system comprises a diaphragm with an outer edge fixedly held by the basin frame and a voice coil configured for driving the diaphragm to vibrate, the voice coil includes a first voice and a second voice coil fixedly connected to the first voice coil, the first and second voice coils are disposed in parallel and symmetrically, the first and second voice coils are integrally wound molded and the winding direction of the first voice coil is opposite to that of the second voice coil. The speaker provided by the present disclosure could improve utilization of magnetic field, provide better vibration effect and reduce resonance frequency.
    Type: Application
    Filed: July 28, 2019
    Publication date: February 6, 2020
    Inventors: Tong Zhang, Chengming Cao
  • Publication number: 20200045438
    Abstract: The present invention provides a sound generator, including a magnetic circuit system having a magnet and a lower plate for carrying the magnet. The magnet includes a first surface opposite to the lower plate and a second surface opposite to the first surface. The first surface of the magnet protrudes to form a first bolt, the lower plate is provided with a lower plate jack matching with the first bolt, and the first bolt is inserted into the lower plate jack. The sound generator of the present disclosure improves the structural stability of the magnetic circuit system and is convenient for positioning.
    Type: Application
    Filed: July 28, 2019
    Publication date: February 6, 2020
    Inventor: Tong Zhang
  • Publication number: 20200045437
    Abstract: The present invention provides a sound generator. A magnetic circuit system of the sound generator forms a mortise-and-tenon structure between a magnet and a lower plate, and the magnet and a pole plate, through tenons and mortises, which enlarges the mutual contact areas, and is more convenient for processing positioning, preventing assembling dislocation, enlarging the gluing area and improving the drop reliability and therefore improving the structural stability of the magnetic circuit system.
    Type: Application
    Filed: July 28, 2019
    Publication date: February 6, 2020
    Inventor: Tong Zhang
  • Publication number: 20200032802
    Abstract: The present disclosure relates to the field of energy storage, and provides a rapid-response energy storage system and a using method thereof.
    Type: Application
    Filed: July 25, 2019
    Publication date: January 30, 2020
    Inventors: Shengwei MEI, Xiaodai Xue, Xuelin Zhang, Tong Zhang, Laijun Chen, Qiang Lu, Tianwen Zheng
  • Publication number: 20200032650
    Abstract: A drive system with both fixed-displacement hydraulic motors and variable-displacement hydraulic motors for a cutter head of a boring machine and a control method thereof are provided. The drive system includes a variable-displacement hydraulic motor group, a fixed-displacement hydraulic motor group and a variable-displacement hydraulic pump group. The variable-displacement hydraulic motor group, the fixed-displacement hydraulic motor group, and the variable-displacement hydraulic pump group are all connected to a main oil circuit of a cutter head system of the boring machine. The variable-displacement hydraulic pump group inputs flow to the main oil circuit; and, the variable-displacement hydraulic motor group and the fixed-displacement hydraulic motor group acquire flow from the main oil circuit. Displacements of the fixed-displacement hydraulic motor group and the variable-displacement hydraulic motor group are set in a way of specific displacement combination.
    Type: Application
    Filed: December 21, 2016
    Publication date: January 30, 2020
    Inventors: Guofang Gong, Xu Yang, Lintao Wang, Chao Wang, Yakun Zhang, Weiqiang Wu, Tong Liu, Liwen Duan
  • Publication number: 20200030339
    Abstract: Disclosed herein is a method for the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject in need thereof a PARP inhibitor, particularly, (R)-2-fluoro-10a-methyl-7,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[def]cyclopenta[a]fluoren-4(5H)-one, a sesqui-hydrate thereof, or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor or a chemotherapeutic agent. Also, disclosed a pharmaceutical combination comprising a PARP inhibitor, particularly, (R)-2-fluoro-10a-methyl-7,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[def]cyclopenta[a]fluoren-4(5H)-one, a sesqui-hydrate thereof, or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor, or a chemotherapeutic agent and the use thereof.
    Type: Application
    Filed: September 27, 2017
    Publication date: January 30, 2020
    Inventors: Lai Wang, Zhiyu Tang, Lusong Luo, Min Wei, Kang Li, Jing Song, Tong Zhang, Hexiang Wang, Bo Ren, Changyou Zhou
  • Publication number: 20200032707
    Abstract: The present disclosure relates to the field of energy storage, and provides a regenerative compressed air energy storage system and a using method thereof. The system comprises a compressor unit, a high-temperature heat exchanger, a medium-temperature heat exchanger, an air storage chamber, a regulating valve, a medium-temperature regenerator, a high-temperature regenerator and an expander unit which are connected in sequence. The low-temperature side of the high-temperature heat exchanger, a high-temperature heat reservoir, a first valve, the high-temperature side of the high-temperature regenerator, a high-temperature cold reservoir and a second valve are connected in sequence. The low-temperature side of the medium-temperature heat exchanger, a medium-temperature heat reservoir, a third valve, the high-temperature side of the medium-temperature regenerator, a medium-temperature cold reservoir and a fourth valve are connected in sequence.
    Type: Application
    Filed: July 25, 2019
    Publication date: January 30, 2020
    Inventors: Shengwei MEI, Xiaodai Xue, Xuelin Zhang, Tong Zhang, Laijun Chen, Qiang Lu, Tianwen Zheng
  • Publication number: 20200034361
    Abstract: A method according to embodiments includes: storing an entire hash table of a table R in memory of a computational storage device; storing a second table S in storage media of the computational storage device, the table R being smaller than the table S, wherein the hash JOIN operation is directed to combining a cs-th column in the table S and a cr-th column in the table R; wherein, for each row of the table S, the computational storage device configured to perform a method, including: applying a hash function to a value of the cs-th column to provide a hash result; looking up the hash result in the hash table stored in the memory of the computational storage device; and if the hash result is found, sending the row of the table S and a corresponding row index of the table R to the host computing system.
    Type: Application
    Filed: July 17, 2019
    Publication date: January 30, 2020
    Inventors: Tong Zhang, Yang Liu, Fei Sun, Hao Zhong