Abstract: The present disclosure relates to compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

Abstract: While displaying a view of a first application of a plurality of applications stored in the memory, an electronic device displays a representation of a first shared content item that upon selection is invoked by the first application, and a selectable attribution affordance that provides a link to a location in a second application where information identifying the first shared content item was initially shared.

Abstract: Systems of the present disclosure can provide a head-mountable device with a head securement element that allows a user to adjust both the magnitude, location, and direction of forces applied to the face of the user. Examples of adjustment mechanisms described herein allow a user to control the tilt of the head-mountable device relative to a head securement element, as well as the tightness of the head securement element. Accordingly, the user can select a fit that distributes forces widely, maximizes comfort, allows the user to enjoy the head-mountable device for longer durations of time.

Abstract: A system may include electronic devices that communicate wirelessly. When positioned so that a pair of devices overlap or are near to one another, the devices may operate in a linked mode. During linked operations, devices may communicate wirelessly while input gathering and content displaying operations are shared among the devices. One or both of a pair of devices may have sensors. An orientation sensor, motion sensor, optical sensor, and/or other sensors may be used in identifying conditions in which to enter the linked mode and to identify a region where displays in the pair of devices overlap.

Abstract: A battery sensor system (BSS) includes a battery operably coupled to a plurality of loads via a wired connection, where a first load is operably coupled to a terminal of the battery via a first portion of the wired connection and a second load is operably coupled to the terminal via a second portion of the wired connection. The BSS further includes a first drive sense circuit operably coupled proximate to the battery to sense a first voltage. The BSS further includes a second drive sense circuit operably coupled proximate to the first load to sense a second voltage, where the second voltage and first voltage are different based on an impedance of the wired connection between the first point and the second point. The BSS further includes memory and processing modules to process the first and second voltages to determine operational status of the battery, wired connection, and loads.

Abstract: A colored (viz., not black) vitreous enamel coating for an electrosurgical metal cutting blade provides heat-resistant, durable blade coloration and facilitates differentiation or discrimination between, or identification of, different blades. Different colors may be employed on different blade shapes in an array of blades, on blades used for different surgical procedures, or on blades used on different tissue types. The color may be applied to a portion of a blade to denote an edge or other feature. The color may preferentially absorb the primarily blue-hued light emitted by an electrosurgery plasma and preferentially reflect light of other hues; make the blade more visible against surrounding tissues; or discourage reflection of visible or other light (e.g., infrared radiation) in colors that might interfere with markers, sensors or other instruments designed to measure light emitted by or passing through nearby tissue such as by transillumination.

Abstract: Polyoxazoline (POZ) conjugates wherein the conformation of the POZ conjugate and the release rate of an agent from the POZ conjugate can be controlled by selecting one or more characteristics of the POZ polymer and methods of controlling the conformation of a POZ conjugate and the release rate of an agent prior are provided as well as methods of treatment using such POZ conjugates and methods. Pharmaceutical compositions including a POZ conjugate are also provided.

Abstract: A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

Abstract: A method of forming a ceramic matrix composite (CMC) vane comprises drawing a continuous fiber sheet over at least one contoured surface to form a single-folded sheet. The single-folded sheet comprises an airfoil portion, a first platform at a first end of the airfoil portion, and an integral transition region between the airfoil portion and the first platform. The method further comprises mounting the airfoil portion on a mandrel, attaching a second platform to a second, opposing end of the airfoil portion to form a vane preform, and densifying the vane preform.

Abstract: A device may include a display portion that includes a display housing and a display at least partially within the display housing. The device may also include a base portion pivotally coupled to the display portion and including a bottom case, a top case coupled to the bottom case and defining an array of raised key regions, and a sensing system below the top case and configured to detect an input applied to a raised key region of the array of raised key regions.

Abstract: Support plates for localized heating in thermal processing systems to uniformly heat workpieces are provided. In one example implementation, localized heating is achieved by modifying a heat transmittance of a support plate such that one or more portions of the support plate proximate the areas that cause cold spots transmit more heat than the rest of the support plate. For example, the one or more portions (e.g., areas proximate to one or more support pins) of the support plate have a higher heat transmittance (e.g., a higher optical transmission) than the rest of the support plate. In another example implementation, localized heating is achieved by heating a workpiece via a coherent light source through a transmissive support structure (e.g., one or more support pins, or a ring support) in addition to heating the workpiece globally by light from heat sources.

Abstract: Methods and apparatus for automated routing of wires of a wire harness on a form board. A wire harness comprising a wire end connector and a multiplicity of groups of wires is supported and carried by a carrier end effector mounted to an end of a first robotic arm. The wire groups are accessed and then routed on the form board by a routing end effector mounted to an end of a second robotic arm. Initially a wire gripper of the routing end effector is opened. The second robotic arm is then controlled to move the routing end effector so that respective first portions of all wire groups are accessible for gripping by the wire gripper. Then the wire gripper is closed to grip the first portions of wires. Then the second robotic arm is controlled to move the routing end effector to place second portions of the wires of all wire groups in a first elastic retainer wire routing device attached to the form board.

Abstract: Methods and apparatus for automated routing of wires of a wire harness on a form board. A wire harness comprising a wire end connector and a multiplicity of groups of wires is supported and carried by a carrier end effector mounted to an end of a first robotic arm. The wire groups are accessed and then routed on the form board by a routing end effector mounted to an end of a second robotic arm. Initially a wire gripper of the routing end effector is opened. The second robotic arm is then controlled to move the routing end effector so that respective first portions of all wire groups are accessible for gripping by the wire gripper. Then the wire gripper is closed to grip the first portions of wires. Then the second robotic arm is controlled to move the routing end effector to place second portions of the wires of all wire groups in a first elastic retainer wire routing device attached to the form board.

Abstract: Characterization of drug-drug interaction properties and pharmacological properties of maribavir is useful to inform potential drug-drug interactions and dosing strategies when administering with co-medications.

Abstract: A handheld light assembly for eradicating pathogens includes a housing. A processor and a lamp are disposed inside the housing. The lamp irradiates surfaces with disinfecting ultraviolet light having a peak wavelength of 222 nm filtered to restrict illumination to between 200 nm and 230 nm within an irradiation zone. A distance measuring system includes a secondary light source generating secondary light and a photodetector for measuring distance of the secondary light to a surface being irradiated by the lamp light being reflected from the surface to the photodetector. The secondary light source is offset at an angle from the lamp thereby projecting the light beam to a central area of the irradiation zone generated by the lamp. The photodetector signals the processor to calculate a vertical distance between the lamp and the central area of the irradiation zone on the surface being irradiated from an angular projection of the secondary light.

Abstract: A class of ketoamide derivatives and an application thereof are disclosed. Specifically disclosed are a compound of formula (IV) and a pharmaceutically acceptable salt thereof.

Abstract: Systems and methods are disclosed for measuring fluid pressure in an ophthalmic surgical system. An example system comprises a fluid flow path and a pressure sensor system for measuring pressure in the fluid flow path. The pressure sensor system comprises a conductive, movable diaphragm having a first side and a second side, the first side of the diaphragm facing the fluid flow path, and an eddy current position sensor positioned on the second side of the diaphragm without contacting the diaphragm. The eddy current position sensor comprises a position sensor coil activatable by high frequency alternating current and signal conditioning electronics capable of sensing inductance or impedance or resonant frequency variation in the position sensor coil as a gap between the diaphragm and the position sensor coil changes and of translating that variation into a displacement signal correlated to fluid pressure. A method of measuring fluid pressure may be performed using one or more of the systems described herein.

Abstract: Pay stations in a retail store initiate customer transactions for customers. When a first pay station is unable to complete a customer transaction, it hands the transaction off to a second pay station that is able to complete the transaction. During hand off, the first pay station determines a first set of biometric and contextual data associated with the customers and sends that information to the second pay station. The second pay station then determines, independently, a second set of biometric and contextual data associated with the customers and compares it against the first set. Depending on the results of the comparison, customers are either granted or denied access at the second pay station to complete the transaction. Additionally, all biometric and contextual data are permanently destroyed without being saved to memory.

Abstract: A computing device includes signal generation circuitry and also includes a location on the computing device that is operative to couple a signal generated by the signal generation circuitry into a user. For example, the computing device includes signal generation circuitry that generates a signal that includes information corresponding to a user and/or an application that is operative within the computing device. The signal generation circuitry couples the signal into the user from a location on the computing device based on a bodily portion of the user being in contact with or within sufficient proximity to the location on the computing device that facilitates coupling of the signal into the user. Also, the signal may be coupled via the user to another computing device that includes a touchscreen display that is operative to detect and receive the signal.

Abstract: An electronic device may have an inner display mounted in a housing so that an image on the inner display is presented to an eye box through a lens for viewing by a user while the electronic device is being worn on a head of the user. The electronic device may have input-output devices that are operable on external surfaces of the electronic device. The input-output devices may be used to gather user input for controlling an external device while the electronic device is not being worn on the user's head. The input-output devices may include a touch screen display, buttons, and other input-output components. An input-output component may be formed on a movable member that can be moved between a stored position and a deployed position. A projector may project images onto nearby surfaces. A removable electronic device may be coupled to head-mounted support structures or other housing structures.