Abstract: Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.

Abstract: A liquid crystal panel includes a first substrate, a TFT layer located on the first substrate, a color resist layer located on the TFT layer, a photospacer layer located on the color resist layer, a protective layer located on the color resist layer and the photospacer layer, a via hole penetrating the color resist layer and the protective layer, a pixel electrode layer formed on the protective layer and electrically connected to the TFT layer with the via hole and a second substrate oppositely located to the first substrate, and one or more color resist material in the photospacer layer and the color resist layer are the same, and the photospacer layer and the color resist layer are formed at the same time during a manufacture process.

Abstract: Disclosed is a method for 3D building extraction, comprising: extracting building footprints from one or more stereo images for a building; determining, from rational polynomial coefficient of the stereo images, first height estimation of the extracted building footprints; obtaining, from multi-temporal SAR images for the building, scatters with stable attributes; determining second height estimation for the determined scatters; and combining the first height estimation and the second height estimation to generate a fused height for each of the extracted building footprints.

Abstract: The present disclosure provides a traffic light for cooperative vehicle-infrastructure and a method for controlling the same. The traffic light for cooperative vehicle-infrastructure includes: a communication module, a central processing module, a Global Positioning System GPS module and a scheduling module. The communication module is configured to receive a set of messages sent by vehicles periodically. The GPS module is configured to locate the position of the traffic light. The central processing module is configured to perform calculations and analyses on the received set of messages and the position of the traffic light, dynamically set lasting times of red and green lamps of the traffic light, and send a control signal carrying the set times to the scheduling module. The scheduling module is configured to control the lasting times of the red and green lamps of traffic light according to the control signal carrying the set times.

Abstract: The present disclosure provides an information processing method and an information processing system. The information processing method is used for controlling a vehicle door, which includes: detecting an action of a vehicle door controlled by an user and feedbacking the action to a processing module through a detecting module; transmitting a control command to a control module according to the detected action through the processing module; and performing the control command to select at least one vehicle door from all vehicle doors and operate the selected vehicle door through the control module. In the technique scheme of the present disclosure, the processing module transmits the control command to the control module according to the detected action; the control module performs the control command to select at least one vehicle door from all vehicle doors and operate the selected vehicle door, thereby increasing the convenience of operating the vehicle door.

Abstract: The present invention provides a LTPS TFT substrate, which includes a black matrix arranged on a first buffer layer of the LTPS TFT substrate to have an area where a TFT device is located is shielded by the black matrix thereby preventing the TFT device from being influenced by light irradiation, maintaining stability of the TFT device; and also saving the manufacturing process of a shielding metal layer, reducing one photo-mask, and lowering down manufacturing cost so as to allow the black matrix, in achieving the functionality of its own (shielding leaking light of the pixel), to also take the place of a shielding metal layer that is commonly adopted in the prior art to shield light for the TFT device and thus providing duality of functionality.

Abstract: The present invention relates to the technical field of medicinal chemistry, and in particular discloses a 2-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof. The compound and pharmaceutically acceptable salt, isomer, racemate, prodrug, co-crystallized complex, hydrate, and solvate thereof can effectively inhibit the BET bromodomain receptor, and can be used for preparing a medicine for treating cancers, cell proliferative disorders, inflammatory diseases, and autoimmune disorders, sepsis, and viral infections.

Abstract: Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.

Abstract: Disclosed is a series of analogs of 4H-pyrazolo[1,5-?]benzimidazole compound as PARP inhibitors. In particular, disclosed in the invention is a compound as shown by formula (I) or a pharmaceutically acceptable salt thereof as a PARP inhibitor.

Abstract: Provided are a series of BTK inhibitors, and specifically disclosed are a compound, pharmaceutically acceptable salt thereof, tautomer thereof or prodrug thereof represented by formula (I), (II), (III) or (IV).

Abstract: A multilevel converter comprising a first switching branch connected between a positive DC-link terminal and an AC output terminal and comprising series-connected first and second switching elements, a second switching branch connected between the AC output terminal and a negative DC-link terminal and comprising series-connected third and fourth switching elements, a third switching branch connected between a DC-link neutral point and a connection point of the first and the second switching elements, a fourth switching branch connected between the DC-link neutral point and a connection point of the third and the fourth switching elements, the fourth switching branch being completely independent from the third switching branch, and a flying capacitor connected between the connection point of the first and the second switching elements and the connection point of the third and the fourth switching elements.

Abstract: A system for purifying mother liquid steam of polytetrafluoroethylene dispersion liquid comprises a concentration kettle (1), a defoaming pot (2), a gas-liquid separator (3) and a falling film absorption tower (4). A steam exit of the concentration kettle (1) is connected to an entrance of the defoaming pot (2). An exit of the defoaming pot (2) is connected to a feeding port of the gas-liquid separator (3). A gas exit of the gas-liquid separator (3) is connected to the falling film absorption tower (4). A liquid exit of the gas-liquid separator (3) is connected to the concentration kettle (1). A method for purifying mother liquid steam of polytetrafluoroethylene dispersion liquid by using the system is further provided.

Abstract: The present disclosure provides a vehicle operation control method, device and system.

Abstract: A capsule containing total flavonoids of Desmodium styracifolium, a method for preparing the same and a use of the capsule containing total flavonoids of Desmodium styracifolium are provided. Specifically, the capsule includes total flavonoids of Desmodium Styracifolium provided in a form of alcohol extract of Desmodium Styracifolium and a pharmaceutically acceptable excipient.

Abstract: Provided is a new method for preparing PARP inhibitor talazoparib.

Abstract: The present disclosure provides a lighting method, system, and streetlamp. The present disclosure may enable the streetlamp to illuminate according to the location of the vehicles, so as to avoid the wasting of electrical energy due to activation of the streetlamp during no passing of vehicles for a long time, by transmitting travelling information for indicating longitude and latitude of an adjacent vehicle by the vehicle, and providing illuminating for the roads upon determining that the vehicle is in the illumination coverage of the streetlamp by the processor in the streetlamp.

Abstract: An origami enabled manufacturing system. The system uses origami design principles to create functional materials, structures, devices and/or systems having an adjustable size and/or shape. An operational device can be coupled to a planar substrate shaped and sized to correspond to a desired origami shape of an origami pattern. A plurality of planar substrates can be coupled together by a plurality of connection members that corresponds to one or more crease of the origami pattern. An array of planar substrates can be formed that convert into a three dimensional structure with origami shape. The resulting three-dimensional structure provides smaller projection area, higher portability and deformability.

Abstract: Provided is a new method for preparing (E)-3-(4-methoxyphenyl)-N-methyl-N-((6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)methyl)prop-2-en-1-amine as a drug intermediate.

Abstract: The present invention provides a LTPS TFT substrate, which includes a black matrix arranged on a first buffer layer of the LTPS TFT substrate to have an area where a TFT device is located is shielded by the black matrix thereby preventing the TFT device from being influenced by light irradiation, maintaining stability of the TFT device; and also saving the manufacturing process of a shielding metal layer, reducing one photo-mask, and lowering down manufacturing cost so as to allow the black matrix, in achieving the functionality of its own (shielding leaking light of the pixel), to also take the place of a shielding metal layer that is commonly adopted in the prior art to shield light for the TFT device and thus providing duality of functionality.