Patents Issued in August 6, 2015
  • Publication number: 20150219550
    Abstract: A method for monitoring a select analyte in a sample in an electrochemical system. The method includes applying to the electrochemical system a time-varying potential superimposed on a DC potential to generate a signal; and discerning from the signal a contribution from the select analyte by resolving an estimation equation based on a Faradaic signal component and a nonfaradaic signal component.
    Type: Application
    Filed: February 13, 2015
    Publication date: August 6, 2015
    Inventors: Sridhar G. Iyengar, Ian S. Harding
  • Publication number: 20150219551
    Abstract: A system and method for testing a material system may include a support structure for mounting the material system, and a electromechanical device operably connected to the support structure, wherein the electromechanical device applies an electromechanical-induced force to the material system, and wherein the electromechanical-induced force causes a displacement in the material system equivalent to material displacement from thermal stress in significantly less time.
    Type: Application
    Filed: February 6, 2014
    Publication date: August 6, 2015
    Applicant: The Boeing Company
    Inventors: Robert B. Greegor, Jeffrey D. Morgan, Quynhgiao N. Le, Julie M. Drexler, John A. Mittleider
  • Publication number: 20150219552
    Abstract: An image processing apparatus includes an illumination unit in which illumination axes of first and second illumination light substantially coincide with an imaging axis and which illuminates an object with the first and second illumination light alternately, the first and second illumination light being respectively polarized in a first direction and a second direction that crosses the first direction; a splitter that divides returning light into at least two returning light components; and first and second polarization imaging devices that receive the returning light components. The first polarization imaging device obtains first and second polarization images polarized in the first direction while the object is being illuminated with the first and second illumination light, respectively. The second polarization imaging device obtains third and fourth polarization images polarized in the second direction while the object is being illuminated with the first and second illumination light, respectively.
    Type: Application
    Filed: January 26, 2015
    Publication date: August 6, 2015
    Inventor: KATSUHIRO KANAMORI
  • Publication number: 20150219553
    Abstract: An apparatus and method (and related kit) for determination of the isotopic ratio of 13C to 12C in a gas sample containing carbon dioxide comprising introducing gas into a gas sample chamber, directing light into the sample chamber from a laser light source, the laser light source being capable of accessing one or more of the wavelength pairs 2054.37 and 2052.42; 2054.96 and 2051.67; or 2760.53 and 2760.08 nanometers, and with a detector detecting the laser light energy after passage through the sample chamber.
    Type: Application
    Filed: April 14, 2015
    Publication date: August 6, 2015
    Inventors: Steven Michael Massick, Kristen A. Peterson, Anthony L. Gomez, Joel A. Silver
  • Publication number: 20150219554
    Abstract: An oxygen analysis system (OAS) for measuring, monitoring and recording oxygen concentration in aircraft fuel tanks. The OAS has a rack support structure installed in an aircraft cabin with a plurality of oxygen analyzer devices mounted in the rack support structure. Each oxygen analyzer device has an oxygen sensor to measure oxygen concentration in gas samples continuously drawn from sample locations in aircraft fuel tanks and at an aircraft NGS ASM exit. The OAS further has a plurality of valves, a supply of calibration gases, a supply of purge and operating gases, and a power distribution assembly, all coupled to the rack support structure. The OAS further has a transport tubing assembly, a plurality of fuel tank gas sampling ports, an NGS ASM exit gas sampling port, a drain manifold assembly, and a data acquisition and recording system having a user interface software to monitor and control the OAS.
    Type: Application
    Filed: January 31, 2014
    Publication date: August 6, 2015
    Applicant: The Boeing Company
    Inventors: Daniel E. Hedges, Mark J. Holland, Scott S. Rhodes, Jennifer D. Klemisch, Jessica C. Pavia, Thomas Michael Henry, Clay J. Anderson, Bruce W. McCaul, Thomas Mac Winsemius, Eric K. Thorson
  • Publication number: 20150219555
    Abstract: Apparatus for measuring light scattering of a sample comprising a light beam source, means for collimating the beam and making it impinge on the sample in a perpendicular direction, at least one light sensor, and at least one spatial filter between the sample and the optical sensor, provided with two apertures, means for measuring the total power reaching the sensor and means for measuring the power of beams with a low k vector after the beam traverses the filter. The invention provides thus a simplified, portable and compact device for measuring different parameters like haze, turbidity, etc. can be built, for any sample and without the need of changing detectors.
    Type: Application
    Filed: February 6, 2015
    Publication date: August 6, 2015
    Applicants: FUNDACIÓ INSTITUT DE CIÈNCIES FOTÒNIQUES, INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS
    Inventors: Valerio PRUNERI, Pedro Antonio MARTÍNEZ CORDERO, Marc JOFRE CRUANYES
  • Publication number: 20150219556
    Abstract: To enable determination of if there is an influence of foreign-body reactions on the result of quantitative determination conducted with a scattered light measurement method. Proposed is an automatic analysis device including a light source configured to irradiate a reaction solution with light, a plurality of light receivers configured to receive scattered light generated from the reaction solution at different light-receiving angles, a first data processing unit configured to process reaction process data measured by one of the light receivers to quantitatively determine a concentration of a substance in the reaction solution, and a second data processing unit configured to determine if the quantitative determination of the concentration of the substance has been performed normally on the basis of a ratio of a plurality of computed values, the plurality of computed values having been calculated from a plurality of pieces of reaction process data measured by the respective light receivers.
    Type: Application
    Filed: June 14, 2013
    Publication date: August 6, 2015
    Inventors: Sakuichiro Adachi, Hajime Yamazaki, Masahiko Iijima
  • Publication number: 20150219557
    Abstract: Material classification of an object is provided. Parameters for classification are accessed. The parameters include a selection to select a subset of angles for classification, a selection to select a subset of spectral bands for classification, a selection to capture texture features, and a selection to compute image-level features. The object is illuminated and a feature vector is computed based on the parameters. The material from which the object is fabricated is classified using the feature vector.
    Type: Application
    Filed: March 2, 2015
    Publication date: August 6, 2015
    Inventors: Sandra Skaff, Chao Liu
  • Publication number: 20150219558
    Abstract: Blood separation systems and methods are provided for controlling the interface between separated blood components. The system includes a centrifuge assembly having a light-transmissive portion, a light reflector, and a fluid processing region therebetween. An optical sensor system emits a scanning light beam along a path toward the light-transmissive portion, which transmits at least a portion of the scanning light beam to the fluid processing region and the light reflector. The light reflector reflects at least a portion of the scanning light beam toward the optical sensor system along a path substantially coaxial to the path of the scanning light beam from the optical sensor system toward the light-transmissive portion of the centrifuge assembly. The scanning light beam may be a white light beam or narrow spectrum beam. The reflected beam may be directed through the optical sensor system via optical fibers.
    Type: Application
    Filed: March 14, 2013
    Publication date: August 6, 2015
    Applicant: Fenwal, Inc.
    Inventors: Peter David Koudelka, Ryan Eliot Eckman, Eric Karl Lindmark, Lubomir Koudelka, James Joseph Ulmes, Steven R. Katz, William H. Cork
  • Publication number: 20150219559
    Abstract: System for visualization of conformal contact. The system visualizes conformal contact between a patterned stamp and a transparent impression surface. A patterned stamp is provided that includes a fluorescent structure for contact with the impression surface. A source of UV light is provided for transmission through the transparent impression surface to interact with the fluorescent structure to generate visible light re-emitted by the fluorescent structure. An imaging system captures the visible light to form a high-contrast image of an area of conformal contact between the patterned stamp and the impression surface. The high-contrast image comprises bright and dark regions representing contact and no contact respectively.
    Type: Application
    Filed: January 30, 2015
    Publication date: August 6, 2015
    Inventors: Larissa F. Nietner, Scott T. Nill, David E. Hardt, Muhammad A. Hawwa, Hassen Ouakad, Hussain Al-Qahtani
  • Publication number: 20150219560
    Abstract: Methods and systems are presented for acquiring photoluminescence images (2) of silicon solar cells and wafers (4) as they progress along a manufacturing line (36). In preferred embodiments the images are acquired while maintaining motion of the samples. In certain embodiments photoluminescence is generated with short pulse, high intensity excitation, (8) for instance by a flash lamp (50) while in other embodiments images are acquired in line scanning fashion. The photoluminescence images can be analysed to obtain information on average or spatially resolved values of one or more sample properties such as minority carrier diffusion length, minority carrier lifetime, dislocation defects, impurities and shunts, or information on the incidence or growth of cracks in a sample.
    Type: Application
    Filed: April 13, 2015
    Publication date: August 6, 2015
    Inventors: Ian Andrew MAXWELL, Thorsten TRUPKE, Robert Andrew BARDOS, Kenneth Edmund ARNETT
  • Publication number: 20150219561
    Abstract: A surface-enhanced Raman scattering element comprises a substrate having a principal surface; a molded layer having a support part formed on the principal surface of the substrate so as to extend along the principal surface and a fine structure part formed on the support part; and a conductor layer formed on the fine structure part and constituting an optical functional part for generating surface-enhanced Raman scattering; the molded layer being relatively thinner in a direction intersecting the principal surface of the substrate at a center edge part of a fine structure area formed with the fine structure part in the molded layer than at an outer edge part of the fine structure area.
    Type: Application
    Filed: August 9, 2013
    Publication date: August 6, 2015
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Masashi Ito, Katsumi Shibayama, Masaki Hirose, Yoshihiro Maruyama
  • Publication number: 20150219562
    Abstract: A SERS element comprises a substrate having a front face; a fine structure part formed on the front face and having a plurality of pillars; and a conductor layer formed on the fine structure part and constituting an optical function part for generating surface-enhanced Raman scattering. The conductor layer has a base part formed along the front face and a plurality of protrusions protruding from the base part at respective positions corresponding to the pillars. The base part has a thickness greater than the height of the pillars.
    Type: Application
    Filed: August 9, 2013
    Publication date: August 6, 2015
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Katsumi Shibayama, Masashi Ito, Takafumi Yokino, Masaki Hirose, Anna Yoshida, Kazuto Ofuji, Yoshihiro Maruyama, Takashi Kasahara, Toshimitsu Kawai, Toru Hirohata, Hiroki Kamei, Hiroki Oyama
  • Publication number: 20150219563
    Abstract: A cable identification system is provided. The cable identification system includes a cable sleeve with some predetermined unique properties. The cable sleeve is adapted to receive a cable therein. The cable includes one or more electrical conductors therein. The cable identification system further includes a portable measuring device configured to detect the predetermined unique properties of the cable sleeve when positioned adjacent the cable at any point along the cable.
    Type: Application
    Filed: April 14, 2015
    Publication date: August 6, 2015
    Inventors: Tamer E. Abuelsaad, John E. Moore, Rajeshkumar N. Singi, Robert R. Wentworth
  • Publication number: 20150219564
    Abstract: The present invention relates to a method for optically determining at least one analyte in a sample, in which a deviation from a reference value or the reference curve is evaluated as an indication that the optical determination of the at least one analyte is corrupted by measurement artifacts.
    Type: Application
    Filed: July 23, 2013
    Publication date: August 6, 2015
    Applicant: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Frank Vitzthum, Herbert Schwarz, Anja Haude-Barten
  • Publication number: 20150219565
    Abstract: A method and apparatus for measuring the thickness of a deposited layer are disclosed herein. Devices as described herein can include a transfer chamber, one or more processing chambers each having an entrance, a loadlock chamber comprising a loadlock entrance and a loadlock exit; and an optical monitoring system comprising a plurality of optical devices positioned proximate to at least one of the entrances. Methods as described herein can include delivering a substrate with at least one deposited layer through an opening in a chamber, activating an optical monitoring system at the opening of the chamber such that the optical monitoring system performs a plurality of optical measurements of the deposited layers, delivering the optical measurements to a signal processing system and correlating the optical measurements to one or more film attributes.
    Type: Application
    Filed: January 30, 2015
    Publication date: August 6, 2015
    Inventors: Ilias ILIOPOULOS, Shuo NA, Kelby YANCY, Chunsheng CHEN
  • Publication number: 20150219566
    Abstract: A system for detecting double-feed flat item conveyed in a mail processing machine, including a detection for directing a beam of radiant energy toward the moving flat items, scanning them with the beam and receiving at least a portion of the beam of radiation reflected from them. The detector includes a triangulation sensor for providing an output proportional to the position at which the reflected portion of the beam is received, and means for determining from the output, the distance (d) between the radiation source and the point of reflection of the beam on the moving flat items, and providing a signal (S) representative of said distance; and a controller configured to receive the signal (S) and generate an output signal (V) indicative of a flat item profile and a double-feed condition when it detects a significant break point or slope change of the signal from a first direction to a second direction.
    Type: Application
    Filed: January 27, 2015
    Publication date: August 6, 2015
    Applicant: NEOPOST TECHNOLOGIES
    Inventor: David AUDEON
  • Publication number: 20150219567
    Abstract: A gemstone tester for characterising a gemstone and a method of characterising a gemstone are provided, the gemstone tester comprising a detector unit for detecting one or more transmittances of the gemstone; and a processing unit for determining a first parameter based on one or more of the transmittances of light; and for characterising the gemstone based on the first parameter; wherein each transmittance of the gemstone is a fraction of light of a specific wavelength that is passed through the gemstone.
    Type: Application
    Filed: October 3, 2013
    Publication date: August 6, 2015
    Inventors: Hwa San Sim, Joanne Yeo
  • Publication number: 20150219568
    Abstract: An illumination apparatus according to embodiments includes: a light source generating laser light; a rotational phase plate having a plurality of randomly arranged stepped regions, the rotational phase plate transmitting the laser light to give a phase change to the laser light; and an integrator including a plurality of lenses arranged in an array, the laser light transmitted through the rotational phase plate being incident on the integrator, an allowable angle of incidence for the laser light of the lenses being set at a maximum value of or larger than an angle of diffraction of a first order of the laser light at the rotational phase plate.
    Type: Application
    Filed: January 28, 2015
    Publication date: August 6, 2015
    Applicant: NuFlare Technology, Inc.
    Inventors: Toshiaki OTAKI, Riki OGAWA
  • Publication number: 20150219569
    Abstract: Provided herein is an apparatus, including a light source configured to illuminate a surface of an article, wherein light incident upon the surface of the article is collimated light; a light detector array including a plurality of light sensors configured to receive scattered light from features about the surface of the article; and a processing means for mapping the features about the surface of the article, wherein the processing means is configured to map the features by analyzing the scattered light received at the light detector array.
    Type: Application
    Filed: April 14, 2015
    Publication date: August 6, 2015
    Inventors: Joachim W. Ahner, S. Keith McLaurin
  • Publication number: 20150219570
    Abstract: The invention concerns an apparatus for inspection of products (3?, 3?), provided with a transport mechanism (2) configured to transport a continuous stream of products (3?, 3?) so that, on leaving the transport mechanism, the product stream (3?, 3?) follows a free-fall path along which it is fed in a single product layer through an inspection zone (16), which has a length (L) that at least corresponds to the width of the aforementioned single product layer, a light source (5, 5?) configured to illuminate said inspection zone (16), a detection unit (6), configured to optically scan the illuminated inspection zone (16), an analysis unit (17) and possibly a removal unit (7) and also a background element (10?), which is situated behind the falling product stream, seen from the position of the detection unit, positioned so that:—light beams from the light source impinge on an illumination zone (14) of the background element when these beams do not impinge on a product from the product stream (3?, 3?),—the detecti
    Type: Application
    Filed: July 15, 2013
    Publication date: August 6, 2015
    Inventor: Bert Dirix
  • Publication number: 20150219571
    Abstract: Highly advantageous impurity detectors and methods are disclosed for detecting impurities in non-polar materials using terahertz frequency electromagnetic radiation to irradiate the non-polar materials and detecting radiation emergent from the non-polar material responsive to the irradiating to determine impurity characteristics.
    Type: Application
    Filed: February 4, 2014
    Publication date: August 6, 2015
    Inventor: Joseph R. Damers
  • Publication number: 20150219572
    Abstract: A method performed by one or more processing devices includes conducting a plurality of tests of a manufacturing process. Each test is conducted at a different combination of at least a first process variable and a second process variable, and each test comprises locally heating a region of a structure, where the local heating results in formation of a thermal field in the structure, and assessing a temperature derivative of the thermal field. Based on results of the plurality of tests, a process map of the temperature derivative of the thermal field is generated, with the temperature derivative based on a function of the first process variable and the second process variable.
    Type: Application
    Filed: August 16, 2013
    Publication date: August 6, 2015
    Inventors: Jack Lee Beuth, JR., Nathan W. Klingbeil, Joy Davis Gockel
  • Publication number: 20150219573
    Abstract: Exemplary embodiments of a high temperature aging cell provide a metal-to-metal fluid seal, and generally include a central tension post containing a flange having an inclined surface; and a seal ring concentrically arranged thereon, its outer circumference positioned at least partly intermediate the flange and the cell interior surface. In various embodiments, a thrust ring retains the seal ring; a thrust washer engages the thrust ring; a tension ring is attached to the tension post for biasing the thrust ring toward the flange; and an outer cap retains various components in relation to the aging cell. A pressure control device allows for pressure elevation. Exemplary embodiments of a sample aging method generally include aging a liquid sample by sealing the sample in the cell via biasing of the seal ring into sealing engagement with an interior surface of the cell. Subsequent sample treatment may involve elevating its temperature and/or pressure.
    Type: Application
    Filed: February 3, 2015
    Publication date: August 6, 2015
    Applicant: OFI Testing Equipment, Inc.
    Inventors: Richard F. Lukay, John D. Norwood
  • Publication number: 20150219574
    Abstract: There is provided a calorimeter. Heat flows in and out of the sample via a thermoelectric module. The thermoelectric module is so constituted that a pair of a P-type thermoelectric element and an N-type thermoelectric element is disposed between substrates, and the pair of the thermoelectric elements are connected in n pairs so that the P-type thermoelectric elements and the N-type thermoelectric element are arranged alternately in ?-shape; a calorimetric sensitivity of the thermoelectric module of a thermal conductance surrounding thermoelectric module and a thermal conductance between substrates of the thermoelectric modules and a noise based on an electric resistance of the thermoelectric module depend on an L/A ratio of the thermoelectric element constituting the thermoelectric module and the number n of the pairs of the thermoelectric elements, where the L/A ratio is 6 mm?1 or more, and the number n of the pairs is 4 or more.
    Type: Application
    Filed: August 7, 2013
    Publication date: August 6, 2015
    Applicant: NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY
    Inventor: Haruhiko Yao
  • Publication number: 20150219575
    Abstract: The invention pertains to a test apparatus and method for assessing thermo-mechanical fatigue related phenomena within a test material wherein a heat source, such as a laser beam is applied to a specimen consisting of a body of the test material, thereby introducing heat to a primary heat introduction zone on the surface of the body to cause local cyclic heating. As part of the cycle, heat is removed through a portion of the specimen surface sufficiently remote from the heat introduction zone to create a substantially spherical temperature gradient within the specimen resembling that of a point source on a semi-infinite body. A stress gradient results from local thermal expansion, thus thermo-mechanically cycling the material. As a result of the thermo-mechanical cycling, phenomena including thermo-mechanically induced creep, residual stress, changes in physical properties, crack initiation and crack growth may be observed within the material, and evaluated for scientific or engineering purposes.
    Type: Application
    Filed: February 5, 2014
    Publication date: August 6, 2015
    Applicant: FRACTURELAB, LLC
    Inventor: Richard G. Pettit
  • Publication number: 20150219576
    Abstract: Disclosed herein is a method of detecting faults beneath a construction supported by earth. The method comprises detecting the conditions of fabric built into the construction supported by earth. One condition of the fabric indicates a fault while a second condition indicates no fault. The detected condition is associated with the location of the fabric that was built into the construction. The detected condition of the fabric is reported. Also disclosed is a fabric that can be included when constructing a road or similar construction such as a highway, railway, runway or dike. The fabric is an array of electronic circuits such that stretching or tearing said fabric will damage electrical characteristics of the fabric. An apparatus for detecting faults beneath a road is also disclosed. The apparatus comprises a fabric built into the road, and a sensor apparatus configured to measure conditions of the fabric at multiple locations. A subset of the conditions of the fabric indicates faults beneath the road.
    Type: Application
    Filed: August 25, 2014
    Publication date: August 6, 2015
    Inventors: Kurt Rudahl, Sally Goldin
  • Publication number: 20150219577
    Abstract: A method includes applying a current to a specimen to deposit a material on the specimen. The method also includes determining a quantity of the material deposited at multiple locations of the specimen and determining anisotropic conductive characteristics of the specimen based on the quantity of the material deposited at the multiple locations on the specimen.
    Type: Application
    Filed: February 6, 2014
    Publication date: August 6, 2015
    Applicant: The Boeing Company
    Inventor: Shahriar Khosravani
  • Publication number: 20150219578
    Abstract: A thermal conductivity detector includes at least four detector components that are arranged in receptacles of a thermal conduction block in a circle around a center axis of the thermal conduction block. The thermal conduction block comprises a central portion along the axis, the cross-axial dimensions of the central portion being less than the diameter of the circle. There are at least four equal peripheral portions that are connected solely to the central portion and are separated from each other, each of the peripheral portions carrying one of the detector components.
    Type: Application
    Filed: January 26, 2015
    Publication date: August 6, 2015
    Applicant: Siemens Aktiengesellschaft
    Inventor: UDO GELLERT
  • Publication number: 20150219579
    Abstract: A method for the detection of autoantibodies comprises detecting autoantibodies in a sample from an individual using label free electrochemical impedance spectroscopy. In one aspect, the method is a method for the diagnosis or monitoring of Parkinson's disease comprising detecting ?-synuclein autoantibodies in a sample from an individual using electrochemical impedance spectroscopy. We also describe electrodes for use in these methods.
    Type: Application
    Filed: July 12, 2013
    Publication date: August 6, 2015
    Inventor: Jason Davis
  • Publication number: 20150219580
    Abstract: A measuring circuit used for the capacitive examination of a moving elongated textile test material such as card sliver, roving, yarn or woven fabric, having a measuring capacitor for accommodating the test material, and a component with a capacitance which can be changed by an electric control signal. The measuring circuit can thus be balanced in a simple, rapid, cost-effective and especially automatic way.
    Type: Application
    Filed: April 7, 2014
    Publication date: August 6, 2015
    Applicant: USTER TECHNOLOGIES AG
    Inventors: Reto Gehrig, Phillipp Ott, Rolf Joss
  • Publication number: 20150219581
    Abstract: A sensor of volatile substances includes: a first electrode structure and a second electrode structure capacitively coupled, comb-fingered, and arranged coplanar in a plane; and a sensitive layer, of a sensitive material that is permeable to a volatile substance and has electrical permittivity depending upon a concentration of the volatile substance absorbed by the sensitive material. The sensitive layer extends from opposite sides of the plane.
    Type: Application
    Filed: January 27, 2015
    Publication date: August 6, 2015
    Inventors: Antonello Santangelo, Salvatore Cascino, Roberto Modica, Viviana Cerantonio, Maurizio Moschetti, Alessandro Auditore
  • Publication number: 20150219582
    Abstract: A sensor of volatile substances including: a sensitive layer, of a sensitive material that is permeable to a volatile substance and has an electrical permittivity depending upon a concentration of the volatile substance absorbed; a first electrode structure and a second electrode structure capacitively coupled together and arranged so that a capacitance between the first electrode structure and the second electrode structure is affected by the electrical permittivity of the sensitive material; and a supply device, configured to supply a heating current through one between the first electrode structure and the second electrode structure in a first operating condition, so as to heat the sensitive layer.
    Type: Application
    Filed: January 30, 2015
    Publication date: August 6, 2015
    Inventors: Antonello SANTANGELO, Salvatore CASCINO, Roberto MODICA, Viviana CERANTONIO, Maurizio MOSCHETTI
  • Publication number: 20150219583
    Abstract: A lead-free galvanic oxygen sensor having an aqueous electrolyte and a bismuth anode is disclosed. The electrolyte contains a polyol in addition to water and a salt. Surprisingly, a sensor with such an electrolyte has an increased resistance to passivation.
    Type: Application
    Filed: February 6, 2014
    Publication date: August 6, 2015
    Inventor: Christa DUMSCHAT
  • Publication number: 20150219584
    Abstract: A method an system is disclosed for the detection and/or allocation of at least one point mutation in target DNA and/or RNA duplexes. The method comprises obtaining a functionalized surface which is coated with probe DNA and/or RNA whereto target DNA and/or RNA duplexes are attached, contacting said functionalized surface to an electrolytic solution having a neutral pH in a flow cell and measuring a first impedance value within said electrolytic solution, and then adding a chemical to the electrolytic solution which is able to achieve denaturation of the target DNA and/or RNA. The method further comprises measuring a second impedance value within the flow cell after completion of the denaturation of the DNA and/or RNA target, and then obtaining a value representative for the impact of the chemical on the impedance of the electrolytic solution.
    Type: Application
    Filed: December 11, 2014
    Publication date: August 6, 2015
    Applicants: IMEC, UNIVERSITEIT HASSELT
    Inventors: Bart Van Grinsven, Ward De Ceuninck, Patrick Wagner
  • Publication number: 20150219585
    Abstract: An electrochemical sensing apparatus and methods are provided. In one embodiment, an apparatus is provided having a carrier that supports an electrochemical module and that communicates between electrodes on the electrochemical module and an analyte measurement device.
    Type: Application
    Filed: February 13, 2015
    Publication date: August 6, 2015
    Inventors: Garry Chambers, Alastair M. Hodges, Ronald C. Chatelier
  • Publication number: 20150219586
    Abstract: A sensor system, device, and methods for determining the concentration of an analyte in a sample is described. Input signals including multiple duty cycles of sequential excitation pulses and relaxations are input to the sample. One or more signals output from the sample within 300 ms of the input of an excitation pulse may be correlated with the analyte concentration of the sample to improve the accuracy and/or precision of the analysis. Determining the analyte concentration of the sample from these rapidly measured output values may reduce analysis errors arising from the hematocrit effect, mediator background, and other error sources.
    Type: Application
    Filed: April 16, 2015
    Publication date: August 6, 2015
    Inventor: Huan-Ping Wu
  • Publication number: 20150219587
    Abstract: An electrochemical test sensor for detecting the concentration of an analyte in a fluid sample. The electrochemical test sensor includes a housing that has a first end and a second opposing end. The housing includes an opening at the first end to receive a fluid test sample. An electrode assembly includes a substrate, a working electrode, a counter electrode and a reagent. The substrate has a first surface and an opposing second surface. The working electrode is disposed on the first surface of the substrate, and the counter electrode is disposed on the second surface of the substrate. The electrode assembly is positioned within the housing to define a reaction channel. The electrochemical test sensor may be used with a removable lancet mechanism or integrated within a lancet mechanism to form one integral unit.
    Type: Application
    Filed: April 16, 2015
    Publication date: August 6, 2015
    Inventors: Yuan Wang, Raeann Gifford, Hualin Jiang, Jeffery S. Reynolds, Jiangfeng Fei
  • Publication number: 20150219588
    Abstract: Methods and systems for measuring the oxidation-reduction potential of a fluid sample are provided. The system includes a test strip with a sample chamber adapted to receive a fluid sample. The sample chamber can be associated with a filter membrane. The test strip also includes a reference cell. The oxidation-reduction potential of a fluid sample placed in the sample chamber can be read by a readout device interconnected to a test lead that is in electrical contact with the sample chamber, and a reference lead that is in electrical contact with the reference cell. Electrical contact between a fluid sample placed in the sample chamber and the reference cell can be established by a bridge. The bridge may comprise filter element such as a piece of filter paper that is wetted, for example by the fluid sample, or an electrolytic gel. The oxidation-reduction potential may be read as an electrical potential between the test lead and the reference lead of the test strip.
    Type: Application
    Filed: April 13, 2015
    Publication date: August 6, 2015
    Inventors: Raphael Bar-Or, David Bar-Or, Leonard T. Rael
  • Publication number: 20150219589
    Abstract: Ion-selective sensor (6) comprising a micro-machined chip with an analyte micro-channel (2), adapted to draw an analyte solution and a first liquid membrane micro channel (3) adapted to draw a liquid membrane solution, and an first electrolyte micro channel (1), adapted to draw an analyte solution. The ion-selective sensor (6) comprises a first substrate (100) and a second substrate (200) comprising each a structured surface to form, after assembly of said substrates the analyte micro-channel (2), the first electrolyte micro channel (1) and the first liquid membrane micro channel (3), each provided with their respective inlet and outlet.
    Type: Application
    Filed: August 14, 2013
    Publication date: August 6, 2015
    Applicant: CSEM Centre Suisse d'Electronique et de Microtechnique SA-Recherche et Dévelopment
    Inventors: Silvia Generelli, Laurent Barbe
  • Publication number: 20150219590
    Abstract: An air-fuel ratio detection device includes a resistor, a first voltage application section, a second voltage application section, an amplification section, an A/D conversion section, and an arithmetic section. The first voltage application section applies a direct current voltage to a first end of a series circuit constituted of an air-fuel ratio sensor and the resistor. The amplification section amplifies a voltage across the resistor and outputs an amplified voltage as an output voltage. The A/D conversion section carries out an A/D conversion of the output voltage every time before the second voltage application section switches a voltage applied to a second end of the series circuit between a first voltage and a second voltage. The arithmetic section calculates a sensor current and an impedance of the air-fuel ratio sensor using two consecutive A/D conversion results by the A/D conversion section.
    Type: Application
    Filed: January 28, 2015
    Publication date: August 6, 2015
    Inventors: Shinya UEMURA, Yusuke SHIMIZU
  • Publication number: 20150219591
    Abstract: A gas sensor element of an air/fuel ratio sensor has a structure in which at least a part of an end portion of a porous electrode is sandwiched between a porous member and a solid electrolyte member. Therefore, it is possible to restrain shrinkage of the porous electrode during manufacture of the gas sensor element, which shrinkage would otherwise occur at the time of heating in a debindering step or at the beginning of a firing step, whereby occurrence of green breakage in the solid electrolyte member is restrained. Thus, cracking due to green breakage is restrained from occurring in the solid electrolyte member produced through firing. Since the end portion of the porous electrode can receive oxygen through the porous member, blackening of the solid electrolyte member can be prevented.
    Type: Application
    Filed: February 3, 2015
    Publication date: August 6, 2015
    Inventors: Yasumitsu SHIMIZU, Seiji OYA
  • Publication number: 20150219592
    Abstract: Devices including an electrode assembly within a nanofluidic channel are provided for electrochemical measurement of the concentration of a redox active substance. Also provided are methods of fabricating the devices and methods of measuring a concentration of a redox active substance using the devices. The devices and methods, and sensors embodying them, provide fast and sensitive detection of the presence of a microorganism by detecting a redox active substance produced by the microorganism while preventing venting access of the microoganism itself to the electrode assembly.
    Type: Application
    Filed: July 22, 2013
    Publication date: August 6, 2015
    Inventors: Edgar D. Goluch, Thaddaeus Webster
  • Publication number: 20150219593
    Abstract: The analysis method allows analysis of samples with high sensitivity, irrespective of interelectrode distance. The method includes: a step of applying a voltage between a first electrode pair such that an electric field is formed in a direction intersecting a migration direction of a sample; a step of placing a solution, including an electrochemically active molecule that produces a redox reaction at the electrode pair, between the first electrode pair; a step of causing the sample to migrate; and a step of measuring an amount of change in current flow between the first electrode pair.
    Type: Application
    Filed: August 2, 2013
    Publication date: August 6, 2015
    Inventors: Tomoji Kawai, Takahito Ohshiro, Masateru Taniguchi
  • Publication number: 20150219594
    Abstract: The present invention relates to amethod and an apparatus for concentrating, detecting and/or isolating a plurality of charged analytes contained in a sampleby depletion zone isotachophoresis.
    Type: Application
    Filed: August 21, 2013
    Publication date: August 6, 2015
    Inventors: Paul Vulto, Thomas Hankemeier, Jos Quist, Kjeld Janssen
  • Publication number: 20150219595
    Abstract: A process for analyzing a sample by a capillary electrophoresis method is provided that allows for high analytic precision and reduction in apparatus size, and can be readily carried out by electrophoresing a complex of a sample and an anionic group-containing compound in the capillary channel, wherein the capillary channel includes an A layer that is coated on an inner wall thereof and a B layer that is coated on the A layer, where the A and B layers are as described.
    Type: Application
    Filed: April 14, 2015
    Publication date: August 6, 2015
    Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, ARKRAY, Inc.
    Inventors: Yoshihide Tanaka, Shinichi Wakida, Yusuke Nakayama, Satoshi Yonehara
  • Publication number: 20150219596
    Abstract: Methods and apparatus providing improved fidelity and specificity when separating nucleic acids from a sample, but without need for amplification. In particular, using the disclosed methods, it is possible to isolate a variant nucleic acid (i.e., a mutation) from a non-target nucleic acid (i.e., a wild-type) when the variant is present in the original sample at a much lower concentration than the non-target, e.g., 1:10,000, without substantial loss of the variant.
    Type: Application
    Filed: April 20, 2015
    Publication date: August 6, 2015
    Inventors: Andrea Marziali, Nitin Sood
  • Publication number: 20150219597
    Abstract: Electrophoresis system comprising at least one type of electrophoresis gel card, at least one type of blot membrane card, an electrophoresis apparatus for running electrophoresis experiments using the electrophoretic gel card, a blot transfer unit for transfer of separated sample from the electrophoresis gel card to the blot membrane card, an imaging apparatus for recording images of separated sample in the electrophoresis gel card and the blot membrane card, wherein; the electrophoresis gel card and the blot membrane card each comprises a rigid support provided with an alignment structure defining a positional reference for mutual alignment during transfer, and for alignment with respect to a complementary alignment structure in the imaging apparatus to provide mechanically aligned images of separated sample in the electrophoresis gel card and the blot membrane card.
    Type: Application
    Filed: May 31, 2013
    Publication date: August 6, 2015
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Camilla Larsson, Henrik Ostlin, Stefan Sjolander, Anders Jahge, Kajas Stridsberg-Friden
  • Publication number: 20150219598
    Abstract: The collision cross section (CCS) of a sample ion may be calculated by measuring a total drift time taken by the sample ion to travel through an ion mobility spectrometry drift cell to an ion detector. The CCS may be calculated based on the total drift time measured, and on a proportionality coefficient that defines the time taken by the sample ion to travel through a mobility dominated region between the drift cell and the detector. The proportionality coefficient may be determined from measuring the total drift times of reference ions. Calculation of the CCS of the sample ion may also be based on a proportionality coefficient that defines the time taken by the sample ion to travel through a mobility-independent region where the velocity of the ion depends on the electrostatic field strength, mass and the charge state of the ion.
    Type: Application
    Filed: January 31, 2014
    Publication date: August 6, 2015
    Applicant: Agilent Technologies, Inc.
    Inventors: Alexander Mordehai, Ruwan T. Kurulugama, Christian Klein, John Fjeldsted
  • Publication number: 20150219599
    Abstract: There is provided a system that detects metal ions in a solution easily and with high precision. Such system includes: a unit that produces a mixed solution by mixing a first solution, which includes a first organic compound that has affinity with metal ions to be measured, and a second solution to be measured and supplies the mixed solution to a container; and a unit that detects the metal ions to be measured in the second solution based on a spectrum obtained by ionizing gas in a head space of the container. An example of the first organic compound is siderophores, such as catechol or AHA. The unit that detects the concentration is an ion mobility sensor and is capable of detecting the concentration of metal ions in a solution in real time.
    Type: Application
    Filed: September 4, 2013
    Publication date: August 6, 2015
    Applicant: ATONARP INC.
    Inventor: Prakash Sreedhar Murthy