Abstract: An occlusion clearing device and system for removing material from an artificial tube in situ includes a clearing stem having aspiration and irrigation conduits, where the irrigation conduit is disposed interior to, and terminates within the aspiration conduit. Material enters the clearing stem through aspiration, and irrigation is provided within the aspiration conduit to assist in aspiration through the clearing stem. A handset includes aspiration and irrigation tubing connecting to sources therefor, and further includes valves to control the flow through the tubing and conduits. These valves may be operated simultaneously with an actuator located on the handset, which may be done with one hand. A coupler at the operative end allows the clearing stem to gain access to the artificial tube for clearing while maintaining a closed system with a ventilator. Reciprocating motion may be generated and provided to the clearing stem to aid in occlusion removal.

Abstract: A filter material of microspheres bonded in a close-packed arrangement is provided. A filter device comprising a funnel containing a filter material of microspheres bonded in a close-packed arrangement is provided. The filter material and filter device are suitable for plasma separation from whole blood.

Abstract: A blood circulation assist system comprising an inflow cannula having a lumen and an insertion device configured to be received therein and to facilitate insertion of a portion of the inflow cannula into a heart chamber. The insertion device includes a shaft having distal and proximal end portions and a plurality of lumens. A first lumen is configured to receive a guidewire and a second lumen is configured to receive a pressurized fluid. A tip connected to the distal end portion of the shaft is configured for insertion into the heart chamber. The tip has a hollow interior communicating with the first shaft lumen. An inflatable member is coupled to the distal end portion of the shaft and includes a hollow interior in fluid communication with the second shaft lumen. The inflatable member is movable between deflated and inflated configurations for releasably securing the insertion device to the inflow cannula.

Abstract: The present invention relates to a dialyzer, in particular to a peritoneal dialyzer, comprising at least one compressor and comprising at least one pneumatic consumer which is in communication with the compressor such that it can be acted on by compressed air from the compressor, wherein the dialyzer communicates or can communicate with at least one blood pressure cuff such that the blood pressure cuff can be supplied with compressed air by the compressor of the dialyzer.

Abstract: Bone bypass shunts and methods using thereof. Method for affecting a pathophysiological condition in a body of a live subject includes exemplary steps/procedures of: connecting an inlet port of a bone bypass shunt to a first bone portion adjacent a first bone marrow location such that inlet port lumen of inlet port facilitates fluid communication with blood accumulated or flowing at first blood marrow location; connecting outlet port of the bone bypass shunt to second bone portion adjacent second bone marrow location, such that outlet port lumen of outlet port facilitates fluid communication with bone marrow; a formed cavity, or/and bone marrow vasculature, located at second bone marrow location; via inlet port lumen, removing a chosen volume of blood from first bone marrow location; and via outlet port lumen, delivering chosen volume of blood to the second bone marrow location.

Abstract: Provided is a method of treating arterial hypertension in a patient. The method comprises selecting a patient suffering from arterial hypertension and creating a flow pathway between a first vascular location and a second vascular location. The first vascular location comprises a source of arterial blood and the second vascular location comprises a source of venous blood. The method causes a reduction in diastolic pressure and a reduction in systolic pressure; and the reduction in diastolic pressure is to an extent at least approximating the reduction in systolic pressure. Systems and devices for creating a flow pathway are also provided.

Abstract: A sound manipulation system is provided. The sound manipulation system includes a flow chamber arranged and disposed to receive a fluid containing a particulate and provide in-line sound wave manipulation of at least a portion of the particulate from the fluid, and a transducer positioned to facilitate the in-line sound wave manipulation within the flow chamber. The flow chamber includes at least a first portion and a second portion, the first portion being self-aligned and secured to the second portion.

Abstract: The present invention relates to a needle arrangement for an injection device. The needle arrangement is made up from needle cannula which is mounted such that a distal part having a distal tip extends in a distal direction. Further, a telescopically movable shield carrying a cleaning chamber surrounds at least the tip of the needle cannula between injections such that the tip of the needle cannula is maintained inside the cleaning chamber between subsequent injections. The cleaning chamber is at least distally provided with a pierceable septum through which the needle cannula penetrates during injections. For guiding the needle cannula during injections a telescopically movable tube is provided. During injections the distal end of the telescopically movable tube at least partly penetrates the distal septum.

Abstract: A pen needle outer cover (10) has a molded plastic distal cover (20), and a molded plastic proximal cover (22) in place of the conventional paper-foil label. The proximal cover (22) may be snap-fit over the opening of the distal cover (20). A user-separable section (26) with a finger pull tab (32) is defined by a reduced-thickness membrane (24), which functions as a tear line to allow that section (26) to at least partially separate from the proximal cover (22). A living hinge (27) may be provided to keep the user-separable section (26) from completely separating from the proximal cover (22). The finger pull tab (32) may be configured to enable re-covering of a pen needle (30) that is still within the outer cover (10).

Abstract: A liquid injector that additionally supplies charged liquid to a patient is provided. The liquid injector includes that continuously supplies a fixed quantity of liquid to a patient only when the fixed quantity of liquid has been charged.

Abstract: A cartridge insertion assembly including apparatus with a pathway formed therein, a cartridge including a cartridge coupling element connectable to an activation mechanism disposed in the apparatus operative to cause a substance contained in the cartridge to be metered out of the cartridge, and a door pivoted to the apparatus that includes a door coupling element arranged with respect to the cartridge such that when the door is in a fully closed position, the door coupling element couples the cartridge coupling element with a coupling element of the activation mechanism.

Abstract: A personal medical device and method of use with restricted mode challenge having a personal medical device including: a memory operable to store programming code; a processor operably connected to the memory; a user input having input buttons to receive input from the user; and a user display to display output to the user. The processor is operable to: detect a user request for entry to the restricted mode; display a user input image on the user display, the user input image including display buttons corresponding to the input buttons; highlight one of the display buttons; detect actuation of one of the input buttons on the user input; and deny entry to the restricted mode when the one of the input buttons does not correspond to the highlighted display button.

Abstract: Disclosed is a method for initializing a dosing unit (20) of an ambulatory infusion system, the method including carrying out a first priming routine. The first priming routine includes: providing the dosing unit (20) with a dosing chamber (202) having a minimal dosing chamber volume, a draining valve (205) being closed and a filling valve (204) being open. The first priming routine further includes measuring an initial reservoir fluid pressure p2 and computing, a first priming volume v1. The method further includes increasing the dosing chamber volume by the first priming volume v1, with the first priming volume v1 being computed such that a reservoir coupling conduit is filled with liquid drug substantially completely at the end of the dosing chamber volume increasing. The first priming routine further includes closing the filling valve (204) and opening the draining valve (205) and emptying the dosing unit (20) by decreasing the dosing chamber volume to the minimal dosing chamber volume.

Abstract: A method for the real-time visualization and detection of extravasated and or infiltrated fluid and substances, including blood, that occur near the cannulation site of an injection is described wherein illumination or transillumination with near infrared light is used to image the contrast in real-time between absorbing and nonabsorbing subdermal and intradermal structures of blood vessels and remaining surrounding tissue, foreign substances and other structures in order to establish a baseline image of the body area of interest, and any new image is monitored and compared with the baseline image to detect the extravasation and/or infiltration of fluids and substances, including blood, around a vein or artery into the subdermal or intradermal tissue.

Abstract: A system for infusing medication into a mammalian subject is provided. The system includes an injection system for controlling a flow of fluid from a fluid reservoir to a needle. A sensor is provided that detects a characteristic indicative of the fluid pressure in the needle. The injection system controls the flow of fluid to the needle in response to the characteristic detected by the sensor and the sensor continuously detects the characteristic as the needle is inserted into the subject. The system further includes a light assembly connected with the injection system. The light assembly provides a continuously variable signal indicative of the fluid pressure in the needle. The system further provides a mechanism that provides cues to prompt the operator to insert the needle at a particular rate based on the detected characteristic.

Abstract: A pumping device that can be used with currently-available pressure bag infusers is disclosed. The pumping device is hand-held and lightweight. The device is controlled by a microprocessor. Thus constant pressure to the bag is maintained through automatic adjustment of pumping and venting functions. In addition, a novel, new pressure bag infuser and a modified Luer Lock fitting for use with the pumping device are described.

Abstract: Infusion devices and related patient management systems and methods are provided. An exemplary method of presenting information pertaining to operation of an infusion device to deliver fluid to a body of a patient involves identifying a plurality of event patterns within different monitoring periods based on measurement values for the patient's condition, prioritizing the identified event patterns based on one or more prioritization criteria, filtering the prioritized list of identified event patterns based on one or more filtering criteria, and then providing a respective pattern guidance display for each identified event pattern remaining in the filtered prioritized list.

Abstract: An assembly for a drug delivery device (200) is provided, the assembly comprising a needle mounting feature (1), a needle detector (2), a housing (3) and a movable feature (4) which is movably connected to the housing (3) and movable with respect thereto between a first position and a second position different from the first position. The needle detector (2) is configured to detect whether a needle (101) is mounted to the needle mounting feature (1). The assembly is further configured such that when a needle (101) is mounted to the needle mounting feature (1), the movable feature (4) is in the second position and when the needle (101) is not mounted to the needle mounting feature (1), the movable feature (4) is in the first position.

Abstract: An injection device, method, and system for drug delivery includes a container for storing a drug, the container having a stopper movably disposed in the container for expelling the drug; an injection drive mechanism having a plunger for acting on the stopper and an energy source having a first selected potential energy for exerting a force on the plunger to cause the plunger to act on the stopper to expel the drug; and a plunger loading mechanism for substantially preventing the plunger from accelerating to a predetermined velocity before it acts on the stopper. The plunger loading mechanism may be a spring having a second selected potential energy for reducing or eliminating a distance between the plunger and the stopper, prior to the plunger accelerating to the velocity. The second selected potential energy of the spring may be less than the first selected potential energy of the energy source.

Abstract: The invention relates to an injection device with a luer fitting. The injection device has a compressible syringe body defining a reservoir. A male luer fitting has a channel therethrough for conducting contents of the reservoir, and a luer tip at an end of said male luer fitting opposing said base end. A first connecting structure is arranged on said male luer fitting between said base end and said luer tip. A shield cap is arranged on the male luer fitting. The shield cap has a second connecting structure interacting with said first connecting structure to prevent inadvertent movement of said shield cap relative to said male luer fitting when said shield cap is arranged at said first position. A first seal is provided for sealing said channel at said luer tip and a second seal is provided for sealing the outer surface and the luer tip.

Abstract: The injection stick is a pole like drug delivery device that allows administration of injection medications from a distance. The design allows for an operator to maintain a safe distance away from a dangerous subject receiving injections. Unlike other injection systems, the injection stick features two design elements to enhance safety and prevent the device from being turned against it's operator by an assailant. The first is a continuously sliding mesh of nylon or other fabric that surrounds all parts of the device except the handle, which simply slides from the outside of the shaft to the inside of the shaft when the device is grabbed and pulled by anyone other than the operator. The second feature is variable flexibility of the shaft, which can be altered from flexible and bendable to stiff depending on the tension applied to the sliding fabric surrounding the shaft of the device.

Abstract: Disclosed are embodiments of a cap covering a needle on a syringe. The cap in the closed configuration is sized and dimensioned to cover the needle, and after the cap is removed from the needle the cap assumes an open configuration that is not readily usable to re-cap the needle.

Abstract: A needle changing device for use on a medication delivery device includes an engagement element that is configured to engage the medication delivery device and pierce a septum of the medication delivery device, a needle holder connected to the engagement element, the needle holder having a needle changing septum having a reservoir, the reservoir being in continuous fluid communication with the engagement element, and a plurality of needles configured to pierce the needle changing septum, wherein when the needle holder is in a first position, the plurality of needles are disengaged from the reservoir of the needle changing septum, and when the needle holder is in a second position, one of the plurality of needles enters into fluid communication with the reservoir of the needle changing septum and is partially exposed outside the needle changing device for medicament delivery.

Abstract: A medical wetness sensing device includes a cover, a first and second electrically conductive portions housed in the cover, an electrically insulative portion housed in the cover, and a compressible portion. The cover defines an outer surface. The first and second electrically conductive portions are exposed along an inner surface of the medical wetness sensing device. The first and second electrically conductive portions are configured to transmit a test signal indicating an absence or presence of a liquid on the inner surface. The electrically insulative portion electrically isolates the first electrically conductive portion from the second electrically conductive portion.

Abstract: A compact wearable inhaler, vaporizer and/or atomizer is addressed by the wearable multifunctional inhaler, vaporizer and smartwatch of the present invention. In the best mode, the invention includes a housing with a chamber having at least port; a lid adapted to engage the housing and open the chamber in a first position and close the chamber in a second position; a source of inhalant mounted within the housing for sourcing inhalant into the chamber via the ports; and an mechanism coupled to the housing for wearing the device. The source of inhalant may be a vaporizer, pipe, inhaler or atomizer.

Abstract: Some embodiments of the invention relate to an inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, comprising: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.

Abstract: The present disclosure discloses a dry powder inhaler comprising a housing with: an air supply channel fluidly connected with an air inlet opening of the housing; a single circulation chamber for deagglomeration of a powder formulation, wherein the circulation chamber is fluidly connected and/or connectable with the air supply channel, and wherein the circulation chamber is arranged downstream of the air supply channel; a mouthpiece fluidly connected with the circulation chamber via an outlet of the circulation chamber, wherein the mouthpiece is arranged downstream of the circulation chamber. The dry powder inhaler according to the present disclosure is characterized in that the dry powder inhaler contains only one single dose of the powder formulation and in that during storage of the powder formulation the powder formulation is in direct contact with the housing.

Abstract: A nebulizer system includes a body having a fluid chamber and an aerosol chamber, and a vibrator assembly positioned at an interface between the fluid chamber and the aerosol chamber. The vibrator assembly may include a diaphragm, having a fluid side and an aerosol side, defining a plurality of perforations between the fluid side and the aerosol side, and one or more vibrator elements operatively associated with the diaphragm to vibrate the diaphragm to produce aerosolized medicament projected into the aerosol chamber from the plurality of perforations. Each perforation of the plurality of perforations projects the aerosolized medicament along a respective projection path relative to a plane defined by the aerosol side of the perforation, the one or more vibrator elements or the diaphragm support substrate further being configured to angularly displace the aerosol side of the diaphragm to sweep the direction of at least one projection path.

Abstract: A breathing gas-carrying patient connection (2) for the artificial respiration of a patient (1) by an anesthesia apparatus or respirator (3) with one or more sensors (9, 10, 11) for detecting patient-relevant measured variables and with a telemetric transmission of the sensor data from the patient connection (2) to a machine-side connection element (13) for the patient connection (2), wherein the telemetric transmission of the sensor data is designed for wireless bidirectional communication between the patient connection (2) and the connection element (13), makes possible the reliable transmission of data into the machine-side connection element (13).

Abstract: A medical gas alarm systems and associated methods are disclosed. A method of monitoring the medical gas system includes the steps of monitoring a characteristic of a medical gas system using at least one monitoring instrument positioned in a medical gas supply network; generating and sending a particular signal from the monitoring instrument to a CPU when the characteristic measured by the monitoring instrument passes a predetermined threshold; generating a fault signal from the CPU when the CPU determines that a fault condition has occurred; retrieving a stored message from the CPU in response to the fault signal, and in which the stored message other than the fault or threshold condition monitored by the instrument; and sending the stored message from the CPU to an output at a medical gas alarm module.

Abstract: A Positive Airway Pressure (PAP) device includes a flow generator that generates a supply of pressurized air. The flow generator includes a programmable controller. The programmable controller is adapted to allow continuous access to at least one active operating mode and selective access to at least one dormant operating mode. The programmable controller includes a mode control system adapted to receive a data signal to control the selective access to the at least one dormant operating mode.

Abstract: A device for delivering medication is presented. The device has a conduit with an upstream end and a downstream end. The downstream end of the conduit delivers the medication. The device has a housing with an open end and an end forming a flat substrate. The housing receives a syringe containing medication and having a plunger. The device also has mechanism for releasing the medication from the syringe and a mechanism for pressurizing the medication. The device has a connector from providing a connection between the syringe and the upstream end of the conduit.

Abstract: A cleaning catheter includes tubular main body, shaped so as to define a distal-most suction orifice; and a suction lumen, a distal portion of which is in fluid communication with the distal-most suction orifice. An outer wall of the main body is shaped so as to define an opening extending through an outer wall into the suction lumen at an axial location proximal to the distal-most suction orifice. An inflatable element is mounted to the main body along the opening. A collapsible membrane is positioned along the opening within an interior of the inflatable element, so as to define an inflatable chamber between a wall of inflatable element and the collapsible membrane. The collapsible membrane is positioned to at least partially occlude the suction lumen upon at least partial inflation of the inflatable chamber. The collapsible membrane is slack when the inflatable chamber is not inflated.

Abstract: A breathing mask, capable of connecting a gas generator for providing gas generated by the gas generator to a user, includes a main body, a gas inputting tube, a one-way valve, and at least one gas exiting tube, wherein the main body further includes a containing part which forms a containing space for containing the nose of the user. The gas inputting tube is connected to the gas generator for providing the gas to the containing space. The one-way valve allows the gas to pass from the gas input tube to the containing space but blocks the gas from the containing space to the gas input tube. The gas exiting tube enables the gas to exit out from the containing space. The user can breathe in the gas generated by the gas generator from the containing space, and the waste air can exit through the gas exiting tube.

Abstract: A liquid-container/ventilation-tube kit for a ventilation system that includes (a) a ventilator, (b) a respiratory humidifier having a housing and a liquid container, the housing having a pair of first electrical contact elements, (c) a first inhalation tube extending from the respiratory humidifier to a Y-piece, (d) a second inhalation tube extending from the ventilator to the respiratory humidifier, and (e) an exhalation tube extending from the Y-piece to the ventilator, the kit including the liquid container having a pair of first connection elements for removable connection of the first and second inhalation tubes thereto, and a pair of second connection elements each attached to a respective one of the first and second inhalation tubes and by which each of the inhalation tubes is pneumatically connected to a respective one of the first connection elements along a first connecting direction, each second connection element having a second electrical contact element that is positioned and arranged such that

Abstract: A system for infusing medication into a mammalian subject is provided. The system includes an injection system for controlling a flow of fluid from a fluid reservoir to a needle. A sensor is provided that detects a characteristic indicative of the fluid pressure in the needle. The injection system controls the flow of fluid to the needle in response to the characteristic detected by the sensor and the sensor continuously detects the characteristic as the needle is inserted into the subject. The system further includes a conductive element for providing electric nerve stimulation, wherein the system provides electric nerve stimulation in response to the sensor detecting a pressure exceeding an upper limit.

Abstract: The present disclosure describes numerous example medical instruments that include an elongated portion having a proximal end and a distal end, and a passage defined therethrough and a soft tip coupled to the distal end of the elongated portion. The tip may be formed from a soft material. In some instances, the soft material may have a hardness less than the material forming the elongated portion. The tip may also include a passage that may be of a substantially equivalent size as the passage of the elongated portion. The tip may be coupled to the distal end of the elongated portion at an engagement site having a surface area greater than a cross-sectional area of the elongated portion.

Abstract: An umbilical vein resuscitation kit has a multiple-way selection valve having at least three inputs and one output; two pre-filled saline-filled syringes, each coupled through pre-flushed tubing to the valve; a catheter of size between 3 and 5 French coupled to the output of the valve; a sealing device at an end of the catheter; where the valve, syringes, and catheter contained in a package sealed to maintain sterility until the package is opened.

Abstract: In some examples, a catheter body includes an outer jacket positioned over a structural support member. A proximal portion of the structural support member comprises a straight or tapered polymer hypotube and a distal portion of the structural support member comprises a distal support member that is more flexible than the polymer hypotube. In some examples, the polymer hypotube defines one or more openings, through which an adhesive may be introduced between the polymer hypotube and an inner liner of the catheter body.

Abstract: The method of treating varicose veins and other vascular diseases provides sclerosant fluid through a catheter into the body vessel to be treated. The catheter has a lumen and a plurality of sidewall exits. The sclerosant fluid is provided under sufficient pressure so that it comes out of each exit as a jet of fluid with sufficient velocity to impinge on the vessel wall substantially orthogonal to the wall and thus minimize dilution of the sclerosant fluid and optimize coverage. A movable sheath on the catheter permits selecting a portion of the exits to be uncovered and thus create an infusion zone for the jets of sclerosant fluid which approximately match a desired treatment zone.

Abstract: A medical device delivery system can be used to advance a medical device to a target area within a patient's vasculature. The system can comprise a catheter, a support sheath, and a core member coupled to a medical device. The core member can be used to longitudinally advanced or retracting medical device within a lumen of the support sheath. The support sheath can be advanced within the catheter until a distal end of the support sheath contacts or abuts a reduced diameter section of the catheter lumen. Thereafter, the core member can be advanced into the catheter lumen toward the target area.

Abstract: A tactile probe for endovascular intervention with feedbacks informative of the range and direction of a contact force includes: a central column (7); a plurality of lateral electrodes (2) around the central column (7); a conductive contact sleeve (1) that is axially and radially movable relative to the central column (7); a top electrode (3) in movable connection with the central column (7); and an alert electrode (4) configured to generate: a lateral contact signal, upon the contact sleeve (1) radially moving relative to the central column (7) and being electrically connected to at least one lateral electrode (2); a top contact signal, upon the contact sleeve (1) axially moving relative to the central column (7) a first distance (d1) and being electrically connected to the top electrode (3); and a warning signal, upon the contact sleeve (1) axially moving relative to the central column (7) a second distance (d2) and being electrically connected to the alert electrode (4).

Abstract: A bi-directional steerable catheter adapted for delivery into a patient's vasculature. The pull wires which are used to tension the deflectable segment of the steerable catheter are wound in parallel around the axis of the steerable catheter on opposite sides of the steerable catheter.

Abstract: A passive MRI-compatible guidewire includes an elongate, flexible tubular shaft, an elongate core wire of non-ferromagnetic material, and an elongate spring coil of non-ferromagnetic material axially surrounding the elongate core wire to form a distal end portion. The core wire includes opposite first and second end portions separated by an intermediate portion. The intermediate portion has a round cross-section, and the first and second end portions each have a non-round cross-section. The first end portion of the core wire resides within an inner lumen of the tubular shaft and is secured therewithin. The spring coil includes opposite first and second ends, and the spring coil second end is secured to the core wire second end portion via polymeric material that forms a rounded distal tip of the guidewire. The guidewire includes a plurality of spaced-apart, passive MRI-visible markers.

Abstract: A guide wire is disclosed, which includes a core portion formed of an elongated object having flexibility, in which the core portion includes a main body portion formed on a proximal side, a flat plate portion formed on a distal side, and a transition portion which connects the main body portion and the flat plate portion, and in which at least one groove portion extending in a direction different from a length direction is formed on a slope of the transition portion in the length direction. In addition, the guide wire includes a coil portion disposed so as to cover the distal side of the core portion.

Abstract: An apparatus for performing a medical procedure includes a balloon comprising an inflatable body. A first releasable or frangible connection is provided to maintain the body at a first diameter up to a first inflation pressure, and to release, such as by disconnecting, and thus allow the body to assume a second diameter, such as at a second inflation pressure greater than the first inflation pressure or upon a manual release of the connection by a clinician. Multiple releasable or frangible connections may be provided, including between portions (folds) of the inflatable body of the balloon. This disclosure also pertains to a non-compliant or semi-compliant balloon having a first inflation diameter corresponding to a first range of inflation pressures and a second inflation diameter corresponding to a second inflation pressure greater than the first range of inflation pressures.

Abstract: A device and method for intravascular treatment of atherosclerotic plaque prior to balloon angioplasty which microperforates the plaque with small sharp spikes acting as serrations for forming cleavage lines or planes in the plaque. The spikes may also be used to transport medication into the plaque. The plaque preparation treatment enables subsequent angioplasty to be performed at low balloon pressures of about 4 atmospheres or less, reduces dissections, and avoids injury to the arterial wall. The subsequent angioplasty may be performed with a drug-eluting balloon (DEB) or drug-coated balloon (DCB). The pre-angioplasty perforation procedure enables more drug to be absorbed during DEB or DCB angioplasty, and makes the need for a stent less likely. Alternatively, any local incidence of plaque dissection after balloon angioplasty may be treated by applying a thin, ring-shaped tack at the dissection site only, rather than applying a stent over the overall plaque site.

Abstract: The devices and methods shown provide for the minimization of extravasation during arthroscopic surgery. The anti-extravasation surgical portal plug allows a surgeon to drain excess fluids from the soft tissue surrounding the surgical field during arthroscopic surgical procedures.

Abstract: Disclosed are cardiac shunts and method of delivery, and in particular, to a shunt to reduce elevated left atrial pressure (LAP). The methods include forming a puncture hole between the left atrium and the coronary sinus, widening the puncture hole, and placing an expandable shunt within the widened puncture hole. A first catheter having a side-extending needle may be used to form a puncture into the left atrium. A second catheter extends along a guidewire and an expandable shunt with distal and proximal flanges is expelled therefrom into the puncture. The shunt defines a blood flow passage therethrough that permits shunting of blood from the left atrium to the coronary sinus when the LAP is elevated. The shunt is desirable formed of a super-elastic material and manipulated with control rods. The shunt defines a tilted flow tube that facilitates collapse into the catheter.

Abstract: A method of stimulating a renal nerve in a human patient comprising, selecting a span of renal artery in the patient for implantation of a self-expanding stent, the artery having a first internal diameter, an artery wall, and being surrounded by peri-adventitial space through which at least one renal nerve extends; measuring the first internal diameter; selecting a self-expanding stent configured to be capable of expanding to have a second diameter that, in an expanded condition once implanted within the artery, is between 2 mm and 4 mm larger than the first diameter; implanting the stent in the span of the renal artery, whereby the stent eventually expands to the second diameter and thereby passes through the artery wall to become embedded in peri-advential space; and at least partially blocking the renal nerve or modulating a function of the nerve.