Abstract: An electromagnetic wave detection apparatus easily detects characteristics of an object with respect to terahertz electromagnetic waves having different polarization directions. The apparatus includes: a first transceiver that transmits a first terahertz electromagnetic wave having a first polarization direction to a medium; a second transceiver that transmits a second terahertz electromagnetic wave having a second polarization direction different from the first polarization direction to the medium; and circuitry that detects a characteristic of the medium from portions of the first terahertz electromagnetic wave and the second terahertz electromagnetic wave that pass through the medium and are received by the first transceiver and the second transceiver respectively.

Abstract: Disclosed is a method for qualitative and quantitative determination of key substances in mixture based on terahertz spectrum. Terahertz spectrum of a reference mixture is trained through an SVR algorithm, and predicting parameters of key substances in the mixture to be determined after a model is generated. According to the method, an initial pure spectrum corresponding to each composition in the mixture does not need to be separately determined, no limitation on the number of samples contained in the mixture, and no limitation on frequency range to be determined, and the proportion requirement of the mixture in the early test stage is not limited, and the SVR model does not need to be re-trained after a database is formed in the later stage, and the result can be obtained immediately after the spectrum of item to be determined is introduced into the algorithm model.

Abstract: A method is provided for detecting a property of a gas comprising: emitting a light, comprising a plurality of wavelengths covering a plurality of absorption lines of the gas, along a first axis, the light being scattered by particles of the gas resulting in a scattered light, generating a sensor image using a detection arrangement configured to receive the scattered light and comprising: an optical arrangement having an optical plane and being configured to direct the scattered light on to a light sensor, the light sensor having at least one pixel columns, wherein the pixel columns are aligned to an image plane and configured to output a sensor image, wherein the first axis, the optical plane, and the image plane intersect such that a Scheimpflug condition is achieved, determining, from the sensor image, properties of the gas at a plurality of positions along the first axis.

Abstract: A device for optical detection of analytes in a sample includes at least two optoelectronic components. The optoelectronic components include at least one optical detector configured to receive a photon and at least one optical emitter configured to emit a photon. The at least one optical emitter includes at least three optical emitters disposed in a flat, non-linear arrangement, and the at least one optical detector includes at least three optical detectors disposed in a flat, non-linear arrangement. The at least three optical emitters and the at least three optical detectors include at least three different wavelength characteristics.

Abstract: A method for detecting or comparing mechanical strength of macro-molecular polymer materials. The detecting method has the steps of measuring the mechanical strength and the maximum value of the fluorescence absorption spectrum of each of the plurality of samples to form a curve relationship or function relationship between the maximum value of the fluorescence absorption spectrum and the mechanical strength; measuring the maximum value of the fluorescence absorption spectrum of the target material, and using the curve relationship or the function relationship to obtain the mechanical strength of the target material. The plurality of samples and the target material are both prepared from a macro-molecular polymer, and the macro-molecular polymer may be composed of disulfonate-difluorobenzophenone, hydroxyindole and difluorobenzophenone as monomers, and the sulfonate groups of the disulfonate-difluorobenzophenone have metal cations.

Abstract: An apparatus for detecting an optical signal emissions includes signal transmission fibers. Each fiber includes cores having the same spatial core arrangement at each end. The first ends are configured to be optically coupled to the signal emission sources. Each fiber is configured to transmit an optical signal between the first end and the second. The apparatus can also include a frame assembly securing the first ends of the fibers in a first spatial fiber arrangement corresponding to a spatial arrangement of the signal emission sources. The frame assembly can also secure the second ends of the fibers in a second spatial fiber arrangement different from the first spatial fiber arrangement. The apparatus can also include at least one signal detector configured to be optically coupled to the second ends of the fibers, and configured to detect an optical signal emitted by each signal emission source.

Abstract: A method of distinguishing between proteinaceous and non-proteinaceous particulates in a fluid sample includes the steps of acquiring a brightfield background image of a membrane filter, introducing a fluid sample onto the membrane filter, acquiring a brightfield image of filtered particles resting on the membrane filter, generating a particle mask based on the brightfield background image and the brightfield image of filtered particles, introducing a fluorescent dye onto the membrane filter, detecting fluorescence on the particle mask, and distinguishing between proteinaceous and non-proteinaceous particulates based on the detected fluorescence. A method for detecting other types of particles, such as polysorbate particles, silicone oil or protein monomers is also disclosed.

Abstract: Provided is a surface-enhanced Raman scattering (SERS) patch configured to be brought into contact with an object and amplify Raman light generated from the object that is irradiated by laser light. The SERS patch includes a flexible substrate including a first surface facing the object and a second surface opposite to the first surface, a SERS layer provided on the first surface and configured to amplify the Raman light generated from the object based on surface plasmons, and a metalens provided on the first surface or the second surface of the flexible substrate, the metalens being configured to focus at least one of the laser light and the amplified Raman light in a propagation direction thereof.

Abstract: Composite particles are provided. The composite particles can comprise: a base particle; a metal layer encompassing the base particle and having a surface on which a plurality of gaps are formed; and markers provided on the metal layer and also provided within the plurality of gaps of the metal layer.

Abstract: The present invention relates to a diagnostic kit for sepsis, comprising: a first core gold nanoparticle having a target capture oligonucleotide coupled thereto, the target capture oligonucleotide binding complementarily to a portion of a sepsis pathogen-specific genome; and a second core gold nanoparticle to which a target capture oligonucleotide having a Raman-active molecule coupled to one end thereof is coupled via the other end thereof, the target capture oligonucleotide including a sequence complementary to a portion of the sepsis pathogen-specific genome which does not overlap with, but is successive to the portion for the first gold nanoparticle, and a method for diagnosis of sepsis, using the same.

Abstract: System, apparatus, and assemblies for the detection of at least one analyte in a sample are shown and described. The system may be an onboard vehicle system to generate an antibiotic test result from an antibiotic analyte assay.

Abstract: Assays (100) may be performed with a luminometer (400) having a chassis (405) that may include a reaction vessel chamber (610). The luminometer (400) may also include a light passage (640) that intersects the reaction vessel chamber (610). The luminometer (400) may also include a cap (415) that, when in a closed configuration, prevents light emitted by external sources from entering the reaction vessel chamber (610) and from entering the light passage (640). The cap (415) may provide access to the reaction vessel chamber (610) when in an open configuration. The luminometer (400) may also include a calibration light source (460) optically coupled to one end of the light passage (640) and a light detector (630) optically coupled to another end of the light passage (640). The light detector (630) may include a sensing element for receiving light from the light passage (640).

Abstract: The present invention discloses an electrochemical immunosensor (ECL). The ECL is configured for detecting Haptoglobin in biological samples. The immunosensor includes nanocomposite of gold nanoparticles, single-walled carbon nanotubes, quantum dots, and chitosan. The immunosensor can also be used for the ECL based detection of other biomarkers and biomolecules, such as Immunoglobulin A and dopamine.

Abstract: An optically transparent matrix including a molecule containing a hydroxyazobenzene group or its derivative embedded in the matrix. An optical system including the optically transparent matrix, an isomerizing light source, and means for measuring absorbance changes from the optically transparent matrix. A method for measuring the quantity of hydrogen bonding gaseous molecules.

Abstract: The application provides a gemstone testing apparatus for testing a specimen. The gemstone testing apparatus includes a handheld casing, a plurality of light sources, a test probe, a photodetector, a processor unit, and a display unit. The test probe is placed at one end of the handheld casing. A first end of the test probe is placed outside the handheld casing. The plurality of light sources is provided for emitting light rays towards an area that is in the vicinity of the first end. The first end is adapted for receiving light rays from the specimen and for transmitting the light rays to a second end of the test probe. The photodetector is arranged to measure an intensity of the light rays from the second end. The processor unit is provided for determining a material of the specimen in accordance to a measurement of the intensity of the light rays.

Abstract: Disclosed herein are optical elements and methods for making the same. Such optical elements may comprise a first layer disposed on a substrate, a second layer disposed on the first layer, a terminal layer disposed on the second layer, and a cap layer disposed on the terminal layer. The cap layer may comprise boron, boron nitride, or boron carbide. Such optical elements may be made using a method comprising depositing a first layer using vapor deposition such that the first layer is disposed on a substrate, depositing a second layer using vapor deposition such that the second layer is disposed on the first layer, depositing a terminal layer using vapor deposition such that the terminal layer is disposed on the second layer, and depositing a cap layer comprising boron, boron nitride, or boron carbide using vapor deposition such that the cap layer is disposed on the terminal layer.

Abstract: A wafer measurement apparatus for measuring a bonding strength of a bonded wafer includes a wafer holder to hold a bonded wafer into which a blade is inserted and where a crack occurs, a lighting assembly including a light source, a light source controller to select the light source of the lighting assembly for detection of the crack reflected in the bonded wafer, on photographing conditions, a photographing assembly to photograph the bonded wafer by using the photographing conditions corresponding to a wavelength of the light source, on sensitivity of the wavelength of the light source, and a calculator to select one photographing condition, transmit the selected photographing condition, and calculate bonding strength, on a crack distance from a blade edge, extracted from an image of the bonded wafer, to a crack edge.

Abstract: A fluid sensor has a core defining a fluid flow path and a cavity member located externally of the core. The cavity member includes an electrically-conductive composite material including a matrix and one or more reinforcing elements embedded within the matrix. The cavity member is configured so as to provide confinement for an electromagnetic field and the core is configured so as to permit transmission therethrough of electromagnetic radiation at a frequency of the electromagnetic field. The electromagnetic field may be a radiofrequency (RF) electromagnetic field. The fluid sensor can be used in the measurement of the composition and/or flow characteristics of fluid in the fluid flow path.

Abstract: Systems and methods for real time, nondestructive inspection of an object being formed by additive manufacturing is provided. The disclosed systems and methods can be used with any additive manufacturing system and can detect defects introduced during fabrication. In operation, additive manufacturing of the object can be paused and the object rotated within the build chamber. An x-ray pulse can then be directed through a linear aperture towards the object being formed inside the build chamber. A linear x-ray detector array can detect the x-ray pulse and an x-ray image of the object being formed can be created. By rotating the object being formed during exposure to the x-ray pulse at least one half of one full rotation, the entire volume of the object can be inspected.

Abstract: Provided are backscatter detection systems and methods implementing sensor arrays comprising flexible scintillators, and associated methods of operations. Specifically, an apparatus for detecting backscatter of a radiation beam formed in response to the radiation beam encountering an object comprises a structure configured to change from a first shape to a second shape. The apparatus further comprises a sensor array which comprises a flexible scintillating panel covering an area of the structure, and configured to conform to the shape of the structure form the first shape to the second shape. The flexible scintillating panel may comprise a plurality of optical fibers enclosed in a semi-rigid casing and coupled to a light detector. The plurality of optical fibers may be arranged in one or more layers. A layer of optical fibers may be arranged in a plurality of clusters or in an interwoven configuration.

Abstract: The apparatus includes a sensor having a multi-portion dielectric composite. A microstrip transmission line is formed on the dielectric composite and includes an input section, radiator portion, and an output section. The dielectric material adjacent the radiator portion is selected to substantially match that of the certain portions of a live organism being sensed, allowing other constituents of the organism to be sensed. This allow the radiator portion to effectively respond as if it were embedded inside the organism, removing substantial uncertainly from the measurement process. By then applying a plurality of signals to the sensor, the reflected and transmitted components of the signal can be measured and used to determine the amount of certain constituents are present in the organism.

Abstract: An electrical charge storage medium comprises a quantity of first electrically conductive particles contained in a non conductive binder (for example polyurethane). The first electrically conductive particles are magnetite particles. The quantity of magnetite particles includes a distribution of particle sizes between sub-micron and tens of microns, and the magnetite particles have a plurality of planar faces, adjacent planar faces connected at a vertex. The particles each have a plurality of vertices. The magnetite particles are irregular in shape and have a low aspect ratio. Electrical charge storage medium is applied to a non-conductive substrate and contacted by two spaced apart electrodes to sense the change in resistance upon intercation with a volatile organic compound.

Abstract: For the use of a solid fraction sensor (17) to evaluate a solid fraction of a target pharmaceutical sample (4, 10) the solid fraction sensor (17) has a first conductor element (5), a second conductor element (7), an operation space (15) and an energy source (13) arranged to generate an electric field in the operation space (15) by means of the first conductor element (5) and the second conductor element (7), comprising positioning the target pharmaceutical sample (4, 10) in the operation space (15) of the solid fraction sensor (17), determining a capacitance between the first and second conductor element (5, 7) with the target pharmaceutical sample (4, 10) located in the operation space (15), and converting the determined capacitance together with information about a composition of a reference pharmaceutical sample having the essentially same dielectric properties as the target pharmaceutical sample (4, 10) and about a thickness of the reference pharmaceutical sample (4, 10) into a solid fraction of the targe

Abstract: Provided are an excreta detection device that is for a diaper and capable of detecting excreta present in the diaper, and an excreta detection reader for transmitting and receiving signals to and from the excreta detection device for the diaper and notifying a user about whether excreta is present. Since the large scale of a resonant frequency is determined on the basis of a capacitor which is isolated from the excreta and not affected by the excreta and the small scale of the resonant frequency that changes due to the excreta may be determined on the basis of a capacitor having a permittivity that changes due to the excreta, the excreta may be detected even when a relatively narrow frequency band is swept. In addition, since excreta sensing is not performed at only a specific resonant frequency but is also performed by comparing resonant frequencies before and after discharge of excreta, the excreta sensing can be performed regardless of the state of the excreta.

Abstract: A processive enzyme molecular sensor for use in a DNA data storage system is disclosed that can extract digital information suitably encoded into a synthetic DNA molecule. In various aspects, such sensors are provided in a high-density chip-based format that can provide the high throughput, low-cost and fast data extraction capability required for large scale DNA data storage systems. The sensor for reading the digital data stored in DNA molecules processes individual encoded DNA molecules directly, eliminating the need for complicated sample preparation such as making copies of DNA or clonal populations of such molecules.

Abstract: An inventive electrochemical sensor has a substrate with proximal and distal regions. The proximal region has at least one contact element configured to communicate with a measurement device. A working electrode is located in the distal region of the substrate and includes a conductive trace. A plurality of enzyme fields are provided, each enzyme field having an enzyme configured for providing a reaction with an analyte. The enzyme fields are spaced apart and each enzyme field is at least partially located on the conductive trace. The conductive trace may be provided in the form of a grid. The enzyme fields can be formed such that they extend beyond one or both edges of the trace or such that they cover only a portion of the full width of the trace. Manufacturing tolerances can be improved.

Abstract: A gas sensor device has a crystalline film of copper(I) bromide, wherein a crystal surface of the copper(I) bromide is formed of a stepped terrace having a flat face and a steep slope.

Abstract: Described herein are ultrasensitive gas sensors based on a vertical-channel organic semiconductor (OSC) diode, along with methods for making such devices, and uses thereof. The organic sensing layer comprises a fused thiophene-based organic polymer that connects top and bottom electrodes to deliver a vertical current flow. The nano-porous top-electrode structure enables the contact between ambient gas molecules and the vertical organic channel. The device has high sensitivity, is easy to process, and has a long shelf life.

Abstract: A sensor may include a sensing element retained within a storage compartment filled with a storage medium, which may also be used as a calibration medium. The sensing element can include a sensing surface located away from the distal end of the sensing element, such that an inactive section of the sensing element can cooperate with a sealing member such as an O-ring to form part of the seal retaining the storage/calibration medium. The sensing element can be extended and retracted from the storage compartment to expose the sensing surface to a process medium, while preserving the storage medium within the storage compartment for post-measurement validation.

Abstract: An immunofixation electrophoresis applicator system and method deposits antisera in spaced apart locations on a substrate where the antisera is deposited as an elongated bead in a first direction and retained against migration in a direction transverse to said first direction at least by surface tension.

Abstract: Provided is a system including: an antisense molecule; a DNA molecule, an RNA molecule, or a combination of DNA and RNA molecules; and an Isotachophoresis (ITP) system. Furthermore, the invention provides a method for sequence-specifically separating and/or identifying a nucleic acid molecule of interest by utilizing the system of the invention to separate and possibly label and/or detect/quantify a nucleic acid molecule of interest.

Abstract: Disclosed are a method for measuring the adhesive strength of a thin film using surface waves, and a computer-readable recording medium having a program for performing same recorded thereon. The method for measuring the adhesive strength of a thin film measures the adhesive strength between a substrate and a thin film by means of an electronic calculator, using sound waves measured from a thin film structure having a thin film formed on a substrate.

Abstract: A tempo-spatial evolution test system for rock breaking in deep and complex environment includes an acoustic emission sensor assembly and an acoustic emission amplifier assembly that are arranged on a rock mechanics test system. A triaxial cavity coupling bracket is arranged on an outer wall of the triaxial cavity and between two sets of acoustic emission sensor assemblies. The triaxial cavity coupling bracket includes a plate-shaped bracket, two sickle-shaped brackets, and at least three bracket bolts, which can be tightly wrapped on the outer wall of the triaxial cavity. A lateral side of the plate-shaped bracket vertically fixes two guide columns. The acoustic emission amplifier assembly is arranged between the two guide columns and is located above the plate-shaped bracket, and the acoustic emission amplifier assembly is connected to the acoustic emission sensor assembly through a signal line.

Abstract: According to one embodiment, a detection system includes a plurality of sensors, a locator, a first counter, and a determiner. The plurality of sensors that detect an elastic wave, the sensors being disposed separately from each other in a direction in which the welded portion extends and each being installed on the first member or the second member. The locator that locates a generation source position of the elastic wave on the basis of outputs of the plurality of sensors. The first counter that accumulates information of generation source positions of a plurality of elastic waves located by the locator to calculate a distribution of generation source positions of the plurality of elastic waves over a predetermined time. The determiner that determines the position of the crack on the basis of the distribution calculated by the first counter.

Abstract: A plug for inserting into an end of a tubular component to be inspected, including an air discharge unit receivable within the tubular component and having an end surface with a plurality of air outlets defined therein, a flow-directing body receivable within the component extending from the end surface of the air discharge unit with the plurality of outlets located radially outwardly of the flow-directing body, and a sealing member connected to the air discharge unit and having an extended configuration where the sealing member extends outwardly of the perimeter of the air discharge unit. A sealing assembly for a plate component to be inspected and a method of inspecting an outer surface of a component are also discussed. The plug and sealing assembly act to prevent an inspection coupling fluid from flowing on non-inspected surfaces of the component.

Abstract: Provided are embodiments for a system and method for performing real-time performance and health monitoring of an ice detector system. Embodiments include sensing, by a current sensor, a current parameter of a drive coil of an ice detector circuit, and monitoring a performance and health of the ice detector circuit based at least in part on the current parameter, where the drive coil is coupled to a feedback coil that is configured to provide a feedback signal to a driver circuit to control the drive coil. Embodiments also include comparing the performance of the ice detector circuit and expected performance of the ice detector circuit, and providing a report based at least in part on the comparison.

Abstract: Methods for transferring a carbon dioxide based separation procedure from a first chromatographic system to a second one involve identifying an average column pressure for the separation in the first system is identified, determining a measured average column pressure for the separation in the second system, and comparing the measured average column pressure with the identified average column pressures. To more closely match the identified average column pressure, the methods involve: (a) altering a cross-sectional area of a column packed with media in the second system; and/or (b) adding makeup fluid along the length of the column in the second system. Columns with the characteristics used in the methods and second chromatographic systems are disclosed.

Abstract: The present invention provides a highly versatile method for amino acid analysis, the method enabling separation and analysis of amino acids in a sample with high precision in a shorter time. This method is a method for amino acid analysis, the method including a step of allowing a sample containing a plurality of amino acids to flow together with an eluent 2 through a separation column 4 packed with a cation exchange resin, thereby separating the amino acids, and a step of detecting the separated amino acids, wherein the eluent 2 is an eluent containing a divalent or higher inorganic acid, a cation source, and water, and having a pH of 5.0 or lower, and the sample is allowed to flow through the separation column 4 heated by applying a temperature gradient including a temperature region of 100° C. or higher.

Abstract: A device for processing samples is disclosed. Interior surfaces of the device, which come in contact with fluids, define wetted surfaces. A portion of the wetted surfaces are coated with an alkylsilyl coating having the Formula I: R1, R2, R3, R4, R5, and R6 are each independently selected from (C1-C6)alkoxy, —NH(C1-C6)alkyl, —N((C1-C6)alkyl)2, OH, ORA, and halo. RA represents a point of attachment to the interior surfaces of the fluidic system. At least one of R1, R2, R3, R4, R5, and R6 is ORA. X is (C1-C20)alkyl, —O[(CH2)2O]1-20—, —(C1-C10)[NH(CO)NH(C1-C10)]1-20—, or —(C1-C10)[alkylphenyl(C1-C10)alkyl]1-20—.

Abstract: Provided is a method for determining, in a sample, enrichments of a first and a second stable-labeled tracer of a target substance including glucose, the first tracer and the second tracer having the same or similar chemical structure as the target substance, the method including: ionizing the first tracer, the second tracer and the target substance of the sample; measuring intensities of ions deriving from the target substance, the first tracer and the second tracer using a mass analyzer; calculating an enrichment of the first tracer from a first ratio of intensity of the ions deriving from the first tracer to the intensity of the ions deriving from the target substance employing a first calibration curve independent of enrichments of each of the second tracer; wherein the mass analyzer is operated so as to resolve an ion peak deriving from a tracer and having a width ?(m/z) at half maximum peak height equal to or smaller than 1×10?2.

Abstract: A plurality of product ion spectra measured over plurality of cycles for each precursor ion mass selection window of two or more precursor ion mass selection windows are received from a tandem mass spectrometer. A product ion extracted ion chroatograms (XIC) is calculated for each precursor ion mass selection window of the two or more precursor ion mass selection windows from the plurality of product ion spectra for each precursor ion mass selection window. Two or more product ion XICs are produced. A two-dimensional binary bit matrix is generated to represent each product ion XIC of the two or more product ion XICs. For each XIC of the two or more product ion XICs, the binary bit matrix is separately initialized with binary values calculated from each XIC and the initialized binary bit matrix is compared with stored information about known compounds to identify known compounds of each XIC.

Abstract: A system for autonomous crop monitoring includes a mobile platform configured to autonomously propel the system to a plurality of locations in a field of the crop and an imaging device. A leaf bending mechanism is configured to bend leaves of a crop plant in the field when an image of the crop plant is being acquired by the imaging device.

Abstract: A method and device for detection of bone in meat identifies fragments larger than about 1 mm using spectral optical imaging and ultrasound. Spectral imaging can detect foreign material proximate to the surface and ultrasound can detect material within the sample. The sample is irradiated by light and reflected light or Raman scattered light measured. The sample is similarly irradiated by ultrasound and reflected or transmitted sound waves give a set of amplitude data points, which include temporal delay. These data points are then processed by statistical methods to derive a set of vectors in n-dimensional space, which are compared to a calibrated data set of derived vectors which have distinct identifying loci for each type of surface, are indicative of the presence or absence of defects.

Abstract: A method for checking an oil as a lubricant for an internal combustion engine includes: performing a laboratory test in which, independently of the internal combustion engine, a three-dimensional temperature-viscosity-shear rate characteristic field which characterizes the oil is determined, which includes a plurality of viscosities, shear rates and temperatures of the oil determined experimentally by the laboratory test and in each case associates shear rates and viscosities with the temperatures; checking whether the temperature-viscosity-shear rate characteristic field meets at least one predeterminable first criterion; and if the temperature-viscosity-shear rate characteristic field meets the first criterion: performing at least one test bench trial in which, via the internal combustion engine, it is checked whether the oil meets at least one predeterminable second criterion.

Abstract: A system features an acoustic sensor configured to mount on a wall of a mixing drum, sense an acoustic characteristic of a mixture of a slurry, including concrete, contained in a mixing drum when rotating, and provide acoustic sensor signaling containing information about the acoustic characteristic sensed; and a signal processor configured to receive the acoustic sensor signaling, and determine corresponding signaling containing information about a slump characteristic of the mixture of concrete contained in the mixing drum, based upon the signaling received.

Abstract: A moistureproof unit for a moistureproof container for accommodating a biochemical test strip is manufactured by uniformly distributing a moistureproof layer of a hydrophilic polymer material on a surface of a carrier, and including water absorption semicircular units in the hydrophilic polymer material. The moistureproof unit is disposed in a container body which houses the biochemical test strip. The moistureproof unit absorbs the moisture in the container body via the moistureproof layer.

Abstract: A user interface used with a medical testing machine provides improved recall and display of the outcomes of tests performed by the machine. Test outcomes and other information are stored in mass storage directly accessible by the medical testing machine. In one aspect, outcomes of tests relating to a particular patient may be recalled. The system may be especially useful for tests that may be performed multiple times for a particular patient over a period of time, for example testing for HbA1c hemoglobin levels in diabetes patients. The user interface presents a set of screens that allow the display of data according to various filters, and so as to provide detailed information about tests performed by the machine.

Abstract: A device for assessing changes in erythrocyte deformability, such as erythrocyte sickling tendency in a controlled hypoxic atmosphere, comprising: an at least partially transparent inner wall, an at least partially transparent outer wall extending parallel with the inner wall, wherein a gap is present between the inner and outer walls for receiving a blood sample, wherein one of said walls is movable parallel to and relative to the other one of said walls so as to exert a shear force to the sample in the gap, a light source arranged to emit light in a perpendicular direction through overlapping transparent parts of the inner and outer walls, a camera arranged to observe the light from the light source after it is emitted through said transparent parts of the inner and outer walls in order to detect and assess a diffraction pattern therein when a blood sample is present in said gap and the movable wall is being moved, and an oxygen sensor arranged to be in contact with the blood sample in the gap between the i

Abstract: Provided herein are chromatin protection therapeutics (CPTs) and methods of targeting chromatin heterogeneity for the treatment of cancer therewith. In particular compositions and methods are provided that target physical variations in chromatin topology, reduce chromatic heterogeneity, and treat cancer or inhibit the development of resistance to other cancer therapeutics.

Abstract: A method for selecting a cancer patient for whom a ketogenic diet therapy would be effective and a method for predicting efficacy of a ketogenic diet therapy in a cancer patient are provided. A method is characterized by obtaining a result of analysis of at least one pre-intake candidate substance selected from the group consisting of acylcarnitine(12:0), acylcarnitine(12:1)-2, acylcarnitine(12:1)-3, acylcarnitine(14:1)-1, acylcarnitine(14:2)-1, acylcarnitine(14:2)-2, acylcarnitine(14:3)-2, acylcarnitine(16:1), acylcarnitine(16:2), anandamide, heptadecenoic acid, hypotaurine, linoleylethanolamide, palmitoleic acid, palmitoylcarnitine, phytosphingosine, quinic acid, uric acid, alanine, citrulline, tryptophan and lysine in a serum derived from a cancer patient prior to intake of a ketogenic diet, and using the result of analysis as an indicator.