Abstract: An apparatus and methods for tissue restoration are provided. The apparatus may include a catheter shaft extending from a proximal end to a distal tip, the catheter shaft defining lumens including an inflation lumen and a light fiber lumen, a coated balloon positioned on a translucent distal segment of the catheter shaft proximal to the distal tip in fluid communication with the inflation lumen, the coated distal balloon comprising a translucent material and a coated material on an outer surface of the coated balloon, and a light fiber positioned in the catheter shaft in the light fiber lumen and extending through the translucent distal segment.

Abstract: Balloon catheters, methods for preparing balloon catheters, and uses of balloon catheters are disclosed. The balloon catheter includes an elongate member, an expandable balloon, and a coating layer overlying an exterior surface of the expandable balloon. The coating layer includes a total drug load of a hydrophobic therapeutic agent and a combination of additives including a first additive and a second additive. The hydrophobic therapeutic agent is paclitaxel, rapamycin, or paclitaxel and rapamycin. The first additive is a surfactant. The second additive is a chemical compound having one or more hydroxyl, amino, carbonyl, carboxyl, acid, amide, or ester groups.

Abstract: A method for influencing cerebral perfusion in a patient by modifying a volume of a volume adaptor introduced into a cerebral ventricle of the patient, the method comprising identifying a timing of a cerebral blood inflow and/or outflow in a cardiac activity of the patient, modifying a volume of the volume adaptor in synchronization to the identified timing of the cerebral blood flow, to an amount sufficient to modify an intracranial pressure in the cerebral ventricle, such that a flow of the cerebral blood flow is enhanced. In some exemplary embodiments of the invention, the inflation duration of the volume adapter is short relative to the cardiac cycle.

Abstract: A method of treating a sinus cavity of a subject includes advancing a distal portion of a light source through a drainage pathway of a sinus cavity and into the sinus cavity and visually observing a transdermal light emitted from the light source. A distal portion of a substantially rigid inner guide member of a balloon dilation catheter is advanced into the drainage pathway, the balloon dilation catheter including a movable shaft including a balloon that is slidably mounted on the substantially rigid inner guide member. The movable shaft and balloon are advanced distally over the substantially rigid inner guide member to place a portion of the balloon in the drainage pathway whereby the balloon is inflated.

Abstract: Certain embodiments of a medicinal applicator can comprise a base, a medicinal cream receiving port in the base, and a shaft extending along a conceptual shaft axis from the base and terminating at an applicator tip. There is at least one exit aperture located along a portion of the shaft. An unobstructed pathway is in communication with the receiving port and the exit aperture. A stop plate that extends essentially radially from the base delineating the base from the shaft. The shaft possesses a shaft outer shape defined by essentially a flat trailing edge and a shaped leading edge. The shaped leading edge comprises a narrow diameter proximal zone that extends along the shaft from the stop plate to a gradually increasing diameter transition zone that extends to a large diameter paddle zone, which terminates into a shaft distal end.

Abstract: To provide a means which makes it possible to hold a microneedle array without an adhesive sheet and protect tips of microneedles. A foam support sheet for a microneedle array, which has an open cell surface on at least one side, the open cell surface being an arrangement portion for the microneedle array holding the microneedle array with a microneedle side of the microneedle array facing downward; as well as a microneedle array sheet consisting of a microneedle array and a foam support sheet, the foam support sheet having an open cell surface on at least one side, and the microneedle array being arranged on the open cell surface with a microneedle side of the microneedle array facing downward.

Abstract: Provided are a microneedle using a laminated manner, a method of manufacturing a microneedle, and a system thereof. The method of manufacturing the microneedle according to an embodiment of the present invention includes extruding a first material using a first nozzle and extruding a second material using a second nozzle, and manufacturing the microneedle through a laminated manner using the extruded first material and second material.

Abstract: Systems and methods are provided for delivering therapy using an applicator guide and a plurality of catheters for delivering, e.g., radiation, drug, RF, laser or ultrasound therapy. The applicator guide includes a through hole channels through which the catheters may be introduced. The through hole channels may be sized such that the plurality of catheters may freely and independently traverse the through hole channels. By positioning the applicator guide over a target area of a patient's skin, the catheters are free to make contact with the patient's skin and conform to any contours of the patient's skin. The catheters may be microneedles that may be locked in the conformed orientation, such that the microneedles may non-invasively penetrate the patient's skin to deliver the therapy transdermally. The applicator guide may be coupled to an afterloader, drug reservoir, pulse generator, and/or power generator controlled by a healthcare provider via a computing device.

Abstract: External and internal expansion vibration lipofilling, methods for shaping the skin of a patient may include modifying the body surface of a patient by forming a tissue injection space in the skin of the patient by externally applying negative pressure to the skin of the patient and simultaneously injecting, adipose cells into the tissue injection space. External and internal expansion vibration lipofilling systems for shaping the skin of a patient are also disclosed.

Abstract: Described herein is an implantable access port device with a catheter compartment which permits lengthening or shortening the catheter in response to changes in tension of the distal catheter. Implantable access port devices are used extensively in the medical field to facilitate the performance of recurrent therapeutic tasks such as repeated drug delivery, drainage, blood sampling, transfusions, or total parental nutrition. In current access port systems, the catheter is rigidly attached to the access port via a connection ring. As such, the system does not provide any flexibility or ability for catheter length adjustments, which can lead to long-term complications such as dislodgement of catheters, migration of catheters, port separation with extravasation, suture disruption, and mechanical failure of the access port system. These catheter-related complications carry serious risks for the patients.

Abstract: A sheath for producing a fully sealed access to the interior of a vessel of an animal or human body comprises a base sheath having a tubular body defining a pass-through channel. The base sheath is adapted to be inserted into the vessel through a vessel aperture. A wall of the tubular body of the base sheath has a through channel. This channel extends in the wall from the distal end towards the proximal end. The channel can be present separately from the pass-through channel of the base sheath or can form a sideways extension of the pass-through channel, at least at the distal end. Such through channel is adapted to conduct blood from the vessel to the proximal end of the sheath when the sheath has been inserted into a vessel.

Abstract: A medical connector for use in a fluid pathway includes a housing configured to permit fluid flow between a first medical device and a second device or location. The medical connector includes a valve member configured to be positioned at least partially within the housing. The valve member is configured to receive the first medical device. The valve member can be moved into a second state. The connector can be adapted for use with a catheter assembly.

Abstract: An introducer sheath assembly for percutaneously delivering a medical device that maintains hemostasis in a patient. The assembly has a hub, a hub cap and a hemostasis valve. The introducer sheath assembly has a longitudinal axis and a lumen formed therein. The hemostasis valve has a frame portion and a valve portion, the valve portion having a plurality of slits that are offset through the thickness of the valve portion therein and an extension of the frame portion formed from an incompressible material. The extension of the frame portion is received by a valve seat feature in the hub, when the valve is received by the hub. The valve seat feature also receives a seating portion of the hub cap as the hub and hub cap are advanced into engagement, the seating portion of the hub cap advanced into the valve seat feature subjecting the incompressible extension of the frame portion to a compressive force.

Abstract: An adaptor for connecting a drug delivery device to a needleless access device having a straight external thread, including engagement means for mounting said adaptor on the drug delivery device, and an internal thread intended to cooperate with said external thread on a determined length, said internal thread showing on a distal part of said length a first major diameter mating that of said straight external thread, wherein said internal thread shows on a proximal part of said length a second major diameter, where the second major diameter is strictly smaller than the first major diameter, said internal thread further including a tapered portion linking said proximal part to said distal part.

Abstract: A disinfection cap is described for connection to a medical connector, the disinfection cap includes a housing having a top wall and sidewall forming a cavity, disinfectant or antimicrobial agent and a ball disposed within the cavity. An outer surface of the housing includes a thread sufficient to interlock with a mating feature of a threaded connector, or more specifically a male luer connector. The cap may also include a peelable seal to prevent the disinfectant or the antimicrobial agent from exiting the cavity. The cavity of the cap may also include one or more ribs disposed on the inner surface of the cavity to retain the ball in the cavity, forming a flow channel as the ball is depressed further into the cavity. An exterior sidewall surface of the housing may include a plurality of grip members.

Abstract: This invention concerns improved single use caps or covers for vascular access devices such as needlefree connectors that are used, for example, in intravenous administration sets and extension sets. Removal of a single use cap or cover according to the invention from a vascular access device destroys the cap such that it cannot be reused. Such single use caps and covers will help ensure compliance with infection prevention protocols in healthcare settings, which will assist in reducing the incidence of healthcare-associated infections (HAIs), particularly catheter-related blood stream infections. Assemblies and kits its including such caps and covers, for example, IV administration and extension sets that include one or more needlefree connectors, as well as methods for using such caps and covers, are also described.

Abstract: The invention comprises an apparatus and a method for aiding function of a heart, comprising the steps of: (1) sensing a pulse; (2) providing a blood flow assist device, comprising: a first electroactive polymer sleeve segment circumferentially positioned about a portion of a first body part and a second electroactive polymer sleeve segment circumferentially positioned about a segment of a second body part; (3) sequentially constricting, timed to the pulse, the first electroactive polymer sleeve segment and the second electroactive polymer sleeve segment to aid the heart in circulation of blood; and (4) repeating the step of sensing the pulse and the step of constricting.

Abstract: Methods and systems are provided for the circulation of blood using a purge-free miniature pump. In one embodiment, a pump is provided that may comprise a housing including a rotor and a stator within a drive unit. In this embodiment, the pump may establish a primary blood flow through the space between the drive unit and the housing and a secondary blood flow between the rotor and stator. In another embodiment, a pump establishes a primary blood flow outside the housing and a secondary blood flow between the rotor and stator. In yet another embodiment, a method is provided for introducing the pump into the body and circulating blood using the pump.

Abstract: The invention comprises an apparatus and a method for operating a cardiac assist pump, comprising the steps of: (1) providing a cardiac monitor comprising: a cardiac output sensor including an activity sensor and at least two of: a pulse oximeter; an electrocardiogram meter; and a blood pressure monitor; (2) receiving time-varying cardiovascular input data, from the cardiac output sensor, related to a transient hemodynamic state of a cardiovascular system; (3) receiving and operating on time-varying activity input data, from the activity sensor, to generate cardiovascular state information; (4) sensing activity with the activity sensor to generate a target cardiovascular state; (5) repeating both the steps of receiving and operating to update the transient cardiovascular state information and the step of sensing to update the target cardiovascular state; and (6) directing the cardiac assist pump to adjust assisted blood flow, yielding the updated transient cardiovascular state, toward the target cardiovascula

Abstract: The present invention relates to electroporation (EP) devices that are able to generate an electroporation causing electrical field at the mucosal! layer, and preferably in a tolerable manner. Further, it includes the generation of a protective immune response, cellular and/or humoral, using the oral EP device along with a genetic construct that encodes an immunogenic sequence.

Abstract: A method of a soft tissue treatment comprises placing an applicator adjacent to a surface of a body part, the applicator including at least one electrode, providing a fastening mechanism fixing the applicator in contact with the body part, providing a radiofrequency energy by the at least one electrode causing a heating of the soft tissue, providing an electric current to the soft tissue by the at least one electrode causing a muscle contraction, and controlling heating of the soft tissue by the radiofrequency energy and parameters of the electric current provided by the at least one electrode via a control unit, wherein an energy flux density of the radiofrequency energy is in a range of 0.01 mW·mm?2 to 10 W·mm?2 and a frequency of the radiofrequency energy is in a range of 0.1 MHz to 25 GHz, and wherein the body part comprises a face or a chin.

Abstract: A topical nerve stimulator patch and system are provided including a dermal patch; an electrical signal generator associated with the patch; a signal receiver to activate the electrical signal generator; a power source for the electrical signal generator associated with the patch; an electrical signal activation device; and a nerve feedback sensor.

Abstract: A stimulation device includes an adaptor component. The adaptor component couples a percutaneous lead to the stimulation device. The stimulation device may apply a stimulation signal to target tissue via the adaptor. A surgeon may place the stimulation device in a container and the adaptor component may be disposed outside of the container. Methods describe prolonged stimulation of target tissue via a stimulation device. The prolonged stimulation may be applied during and after a surgical procedure.

Abstract: A subcutaneously implantable device includes a clip that is configured to anchor the subcutaneously implantable device to a muscle, a bone, and/or a first tissue, and a first prong with a proximal end secured adjacent to the clip and a distal end extending away from the clip that is configured to contact an organ, a nerve, and/or a second tissue. A first electrode on the first prong is configured to contact the organ, the nerve, and/or the second tissue. A cable is conductively coupled to the first electrode, wherein the cable is configured to be connected to a remote device to electrically couple the subcutaneously implanted device to the remote device.

Abstract: A vestibular stimulation array is disclosed having one or more separate electrode arrays each operatively adapted for implantation in a semicircular canal of the vestibular system, wherein each separate electrode array is dimensioned and constructed so that residual vestibular function is preserved. In particular, the electrode arrays are dimensioned such that the membranous labyrinth is not substantially compressed. Furthermore, the electrode array has a stop portion to limit insertion of the electrode array into the semi-circular canal and is still enough to avoid damage to the anatomical structures.

Abstract: Devices and methods for manipulating devices such as micro-scale devices are provided. The devices can include a tether of various materials surrounded by a stiff body. The tether interfaces with microscale devices to draw them against the stiff body, holding the microscale devices in a locked position for insertion into or extraction out of tissue. The tensional hook and stiff body are configurable in a multitude of positions and geometries to provide increased engagement. Such configurations allow for a range of implantation and extraction surgical procedures for the device within research and clinical settings.

Abstract: Systems, devices, and techniques are disclosed for forming an elongate lead body module of a modular lead. The method may comprise rotating a mandrel, wherein the mandrel extends through a through-hole of a conductor hub, wherein each conductor of a plurality of conductors extend through a respective channel of a plurality of channels of the conductor hub, wherein each conductor of the plurality of conductors extends from a respective bobbin of plurality of bobbins to the channels, wherein the plurality of bobbins are coupled to a carriage, the carriage defining a central opening through which the mandrel passes. The method may comprise moving the carriage away from the conductor hub along a length of the mandrel while the mandrel rotates causing the conductors to coil around the mandrel.

Abstract: Apparatuses, systems and methods are provided for treating pulmonary tissues via delivery of energy, generally characterized by high voltage pulses, to target tissue using a pulmonary tissue modification system (e.g., an energy delivery catheter system). Example pulmonary tissues include, without limitation, the epithelium (the goblet cells, ciliated pseudostratified columnar epithelial cells, and basal cells), lamina propria, submucosa, submucosal glands, basement membrane, smooth muscle, cartilage, nerves, pathogens resident near or within the tissue, or a combination of any of these. The system may be used to treat a variety of pulmonary diseases or disorders such as or associated with COPD (e.g., chronic bronchitis, emphysema), asthma, interstitial pulmonary fibrosis, cystic fibrosis, bronchiectasis, primary ciliary dyskinesia (PCD), acute bronchitis and/or other pulmonary diseases or disorders.

Abstract: A “localizable” systemic gene therapy system is provided substantially increasing the transfection efficiency of the gene vectors into targeted tissue cells and substantially reducing the escape of the gene vectors from the targeted tissue volume, such as would waste the vectors, promote undesired immune reactions, and/or incur prohibitive costs for the required dose of gene-containing virus vectors. In this regard, the invention provides a means to simultaneously achieve local electroporation and gene-containing vector injection in a portion of a vascularized organ. It includes two double-balloon catheters that create contained volumes in parallel blood vessels for the introduction of vectors with reduced loss along with electrodes providing electroporation of the cells in the same location where the vectors are injected.

Abstract: A face lifting device is shown and described. The face lifting device is comprised of a facemask. The facemask has a plurality of electrodes secured to an interior side thereof. The electrodes are electrically coupled to a power source. The powersource is electrically coupled to an on/off device.

Abstract: A pulse generation system is disclosed. The pulse generation system includes a controller, an output terminal, and a plurality of pulse generator circuits. The controller is configured to cause a driving signal pulse to be transmitted to any selected one or more of the pulse generator circuits, and to cause the driving signal pulse to not be transmitted to any selected one or more other pulse generator circuits. Each of the pulse generator circuits is configured to generate an output voltage pulse at the output terminal in response to the driving signal pulse being transmitted thereto.

Abstract: A device for loading a leadless pacemaker onto a catheter-based delivery system includes a distal portion and a proximal portion. The distal portion includes a retention feature configured to receive the leadless pacemaker. The proximal portion is proximal the distal portion and includes a funneling structure opening toward the retention feature. The distal and proximal portions of the device are configured such that, when a distal end of the catheter-based delivery system is brought towards the proximal portion of the loading device and the leadless pacemaker is retained by the retention feature, the funneling structure guides features of the distal end of the catheter-based delivery system through an opening in an attachment feature located at a proximal end of the leadless pacemaker.

Abstract: The invention comprises a method and apparatus for delivering electrons to skin of a person, comprising the steps of: (1) attaching a longitudinal length of a flexible electrically conductive tape to the skin of the person, the flexible electrically conductive tape comprising: an electrically conductive strip and an adhesive layer, the adhesive layer comprising a top surface and an adhesive surface, (2) the adhesive surface affixing the electrically conductive strip to the skin, where the adhesive layer comprises a set of apertures therethrough to form longitudinally distributed electrical contact points along a length of the electrically conductive strip; and (3) an energy source delivering electrons, under control of an electrical control circuit of a controller, to the electrical contact points of the flexible electrically conductive tape.

Abstract: The inventive concept refers to a system, a method, and a computer program for providing training for pain improvement. According to an exemplary embodiment, a training providing method for pain improvement includes requesting, by a computer, a temperature providing device to provide a first temperature to a first body point, requesting, by the computer, the temperature providing device to provide a second temperature to a second body point, requesting a user to select a temperature matched with a specific condition among the first temperature and the second temperature, and calculating a correct answer rate after performing a trial of distinguishing between the first temperature and the second temperature by a predetermined number.

Abstract: A topical nerve activation patch includes a flexible substrate, a dermis conforming bottom surface of the substrate comprising adhesive and adapted to contact a dermis of a user, a flexible top outer surface of the substrate approximately parallel to the bottom surface, a plurality of electrodes positioned on the patch proximal to the bottom surface and located beneath the top outer surface and coupled to the flexible substrate, a power source, and electronic circuitry that generates an output voltage applied to the electrodes. The electronic circuitry includes a controller, a voltage monitoring circuit coupled to the controller, a current monitoring circuit coupled to the controller, a switch coupled to the controller and a boosted voltage circuit coupled to the switch and the power source.

Abstract: A power control circuit for use with devices that will be placed in a flammable sterilizing gas includes a bi-stable switch that is configured to produce an output to place the circuitry of a connected device in a run state or a sleep state. The bi-stable switch controls one or more transistors to drain energy from energy storage devices in the circuitry of the connected device to a level below an ignition level of a sterilizing gas. A remotely actuatable switch can be actuated from outside of a packaging in which the power control circuit is placed to cause the bi-stable switch to produce an output that puts the circuitry in the run state without removing the power control circuit from the packaging.

Abstract: The present invention relates to an electroceutical system for driving a photoelectric element implanted in a sub-retinal optic nerve using a smart photonic lens. According to the present invention, by artificially emitting the light of the smart photonic lens to a photoelectric element connected to the optic nerve, it is possible to utilize stimulation of the nerve with an electric current generated in the photoelectric element to treat various diseases.

Abstract: Various methods and apparatus for treating a condition associated with impaired glucose regulation in a subject comprising in one embodiment, applying a neural conduction block to a target nerve at a blocking site with the neural conduction block selected to at least partially block nerve pulses. In another embodiment, combinations of down-regulating and or up-regulating with are used to treat impaired glucose regulation. In other embodiments, up-regulation or down-regulation of various nerves, such as the vagus and its branches, are used to modify the secretion of insulin and glucagon from the pancreas, thereby controlling glucose levels. In yet further embodiments, combinations of down-regulating and or up-regulating are used to control sensitivity of the liver to plasma insulin and glucagon to treat impaired glucose regulation.

Abstract: Apparatus and methods for managing pain uses separate varying electromagnetic fields, with a variety of temporal and amplitude characteristics, which are applied to a particular neural structure to modulate glial and neuronal interactions as a mechanism for relieving chronic pain. In another embodiment, a single composite modulation/stimulation signal which has rhythmically varying characteristics is used to achieve the same results as separate varying electromagnetic fields. Also, disclosed is an apparatus and method for modulating the expression of genes involved in diverse pathways including inflammatory/immune system mediators, ion channels and neurotransmitters, in both the Spinal Cord (SC) and Dorsal Root Ganglion (DRG) where such expression modulation is caused by spinal cord stimulation or peripheral nerve stimulation using the disclosed apparatus and techniques.

Abstract: An example of a system may include an electrode arrangement and a neuromodulation device configured to use electrodes in the electrode arrangement to generate a neuromodulation field. The neuromodulation device may include a neuromodulation generator, a neuromodulation control circuit and a storage. The storage may include a stochastically-modulated neuromodulation parameter set and the stochastically-modulated neuromodulation parameter set may include at least one stochastically-modulated parameter. The controller may be configured to control the neuromodulation generator using the stochastically-modulation parameter set to generate the neuromodulation field.

Abstract: An example of a system may include an electrode arrangement and a neuromodulation device configured to use electrodes in the electrode arrangement to generate a neuromodulation field. The neuromodulation device may include a neuromodulation generator, a neuromodulation control circuit and a storage. The storage may include a stochastically-modulated neuromodulation parameter set and the stochastically-modulated neuromodulation parameter set may include at least one stochastically-modulated parameter. The controller may be configured to control the neuromodulation generator using the stochastically-modulation parameter set to generate the neuromodulation field.

Abstract: A planning and/or control system for providing stimulation is disclosed. The system can include a graphical presentation module configured and arranged for providing graphical information about an electrode array comprising multiple electrodes and/or an implantation side for the electrode array comprising at least one target area, a selection module configured and arranged for determining a stimulation zone and/or a stimulation direction on the electrode array comprising at least one electrode and/or for individually selecting at least one electrode and/or for selecting at least one target area, and a calculation module configured and arranged for determining a contribution of currents provided by electrodes of the stimulation zone and/or stimulation direction on the electrode array and/or the at least one electrode selected and/or to the at least one target area selected.

Abstract: In some examples, a medical device system includes an electrode. The medical device system may include impedance measurement circuitry coupled to the electrode, the impedance measurement circuitry may be configured to generate an impedance signal indicating impedance proximate to the electrode. The medical device system may include processing circuitry that may be configured to identify a first component of the impedance signal. The first component of the impedance signal may be correlated to a cardiac event. The processing circuitry may be configured to determine that the cardiac event occurred based on the identification of the first component of the impedance signal.

Abstract: There is provided a feedthrough including a ceramic body; and a plurality of electrical conductors embedded in the ceramic body. Wherein the density of the electrical conductors exceeds 1 conductor per 23 thou2 (14,839 ?m2) through a planar cross-section of the ceramic body.

Abstract: Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.

Abstract: Wirelessly networked systems of implantable and non-implantable medical devices with networking protocols, software, and hardware that allow for communications and energy transfer between different the medical devices (free standing, implants and wearables) using ultrasonic waves. The networks and methods of use are used to construct cardiac pacing, deep brain stimulation, and neurostimulation networks based on ultrasonic wide band technology.

Abstract: Systems, apparatus, methods and computer-readable storage media facilitating telemetry overuse reduction in a medical device, such as an implantable medical device (“IMD”) are provided. In one embodiment, an IMD includes a housing configured to be implanted at least partially within a patient, a memory and circuitry within the housing and a processor that executes executable components stored in the memory.

Abstract: A patient-coupled resuscitation device for use with a plurality of medical devices is provided. The resuscitation device includes a portion configured to provide treatment, a connector configured to connect the resuscitation device to one of a first medical device and a second medical device, and a housing including a memory and associated circuitry. The memory and associated circuitry is configured to store a device identifier to identify the resuscitation device; receive medical treatment information from the first medical device, the medical treatment information including at least one of: patient physiological data, patient characteristic data, and rescuer performance data; receive timing information of the medical treatment information from the first medical device; record the medical treatment information and the timing information; and transfer, upon detecting a connection to the second medical device, the medical treatment information and the timing information to the second medical device.

Abstract: Systems to confirm authenticity of electrodes and to provide compatibility between a medical device and associated electrodes are described. The systems include an electrode connector that stores an authentication code that is accessible to the medical device when the electrode connector is coupled to the medical device. The medical device uses the authentication code to determine an authenticity of the coupled electrodes. The electrode connector also includes physical features of a housing that allow the electrode connector to couple to different versions (e.g., older and new models) of the type of medical device. This feature allows reverse compatibility of the electrode connector to different versions of medical devices.

Abstract: An ambulatory medical device is provided. The device includes battery lock circuitry configured to transmit a lock signal at a beginning of a battery lock period of the ambulatory medical device and transmit an unlock signal upon detecting an unlock triggering event indicating an end of the battery lock period of the ambulatory medical device. The device also includes a battery being configured to be securely disposed within a chamber of the ambulatory medical device in a first locked manner and provide power to the ambulatory medical device and a battery lock configured to mechanically engage the battery in a second locked manner upon receiving the lock signal indicating the beginning of the battery lock period of the ambulatory medical device and mechanically disengage the battery from the second locked manner upon receiving the unlock signal signaling the end of the battery lock period.