Therapy Patents (Class 378/65)
  • Patent number: 11324474
    Abstract: A medical image diagnostic system according to an embodiment includes processing circuitry configured to acquire first information related to an exposure dose of a subject by a radioactive agent administered to the subject, and display reference information for determining imaging conditions of X-ray CT imaging to be performed with respect to the subject on a display, based on the first information and second information related to a reference dose.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: May 10, 2022
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Yuji Hamada, Naoki Sugihara, Manabu Teshigawara
  • Patent number: 11324972
    Abstract: The present disclosure discloses a laser verification apparatus employed in a radiotherapeutic device which comprises a plurality of radioactive sources, a collimator comprising a plurality of collimating holes, and a couch. The radioactive sources are capable of aligning in respect to the collimating holes respectively.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: May 10, 2022
    Assignee: OUR NEW MEDICAL TECHNOLOGIES
    Inventor: Haifeng Liu
  • Patent number: 11315440
    Abstract: A respiratory gating phantom device includes a first airbag, a second airbag, a first catheter, a second catheter, a fixture, and an air pressure gating device. The first catheter and the second catheter are respectively installed in the first airbag and the second airbag. The fixture is provided with a phantom tumor and adjustably installed in the first catheter or the second catheter, thereby installing the phantom tumor in the first catheter or the second catheter. The air pressure gating device, connected to the first airbag and the second airbag, inflates and deflates the first airbag and the second airbag to simulate breathing. The first catheter and the second catheter respectively move along three-dimensional direction and two-dimensional direction in response to motions of the first airbag and the second airbag.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: April 26, 2022
    Assignee: NATIONAL CHUNG CHENG UNIVERSITY
    Inventor: Ying-Hao Yu
  • Patent number: 11301998
    Abstract: A method and a system are for calculating an output from a tomographic scrollable image stack, including a large number of generated sectional images of a tissue to be examined. In this context, a tomographic scrollable image stack is received. An output for a display is calculated. The output includes a primary image that is intended for representing the received image stack, and the output includes a secondary image with additional information. The secondary image is displayed overlaid on the primary image once an unhide signal or hide signal is received. In this context, a reference may be provided between the additional information of the secondary image and the slice of tissue for examination that is shown in the sectional image of the image stack.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: April 12, 2022
    Assignee: SIEMENS HEALTHCARE GMBH
    Inventors: Matthias Baer-Beck, Sebastian Faby, Rainer Raupach, Andre Ritter
  • Patent number: 11291856
    Abstract: A method of optimizing a radiotherapy treatment plan is disclosed, comprising the steps of: a. obtaining a deliverable input treatment plan; b. optimizing the deliverable input treatment plan to obtain an optimized treatment plan, using an objective function and at least one constraint, wherein i. the objective function is related to reducing the plan complexity in terms of minimizing the machine output (MU) and/or minimizing the time required to deliver the plan and/or maximizing the segment area, and/or minimizing jaggedness of the MLC shapes, ii. to ensure that the quality is maintained, the at least one constraint is based on the dose distribution of the input plan, related to maintaining an acceptable dose distribution.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: April 5, 2022
    Assignee: RaySearch Laboratories AB
    Inventor: Kjell Eriksson
  • Patent number: 11291858
    Abstract: Generating a plan for radiation treatment of multiple target volumes such as, for example, multiple brain tumors, involves optimizing a grouping of the target volumes into subsets and generating treatment plans for each subset. Resulting treatment plans may minimize radiation dose to tissues outside of the target volumes. A radiation treatment planning system may be configured to operate in this manner and to upload control signals which cause a radiation therapy device such as a linear accelerator to execute the radiation treatment plans.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: April 5, 2022
    Assignee: Dalhousie University
    Inventors: Robert Lee MacDonald, Alasdair Syme, Christopher G. Thomas
  • Patent number: 11294076
    Abstract: A radiation dosimeter for measuring radiation dose within a region includes a structure having a scintillating material that emits light when exposed to radiation. Deformable radio-luminescent elements are located within the structure and configured to generate optical energy in response to irradiation.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: April 5, 2022
    Assignee: UNIVERSITÉ LAVAL
    Inventors: Louis Archambault, Luc Beaulieu, Émily Cloutier
  • Patent number: 11285341
    Abstract: The present invention provides electron beam therapies with improved feedback control that delivers controlled and adjustable doses of electron beam radiation to variable shallow depths with little radiation exposure to both nearby tissues and tissues below the target. In order to control radiation to accurately penetrate to shallow depths and to allow the radiation to be adjusted to other depth settings in very small or even continuous increments, the present invention senses a plurality of different electron beam characteristics and then uses these to derive a composite characteristic, or analog, of the electron beam energy. The composite analog provides a strong correlation to energy that allows this precision. In another aspect, the present invention relates to implementing this feedback control by adjusting power levels used to establish the electron beam.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: March 29, 2022
    Assignee: INTRAOP MEDICAL CORPORATION
    Inventors: Donald A. Goer, Alexandre S. Kretchetov, David H. Whittum, James A. Nelson
  • Patent number: 11273326
    Abstract: According to one embodiment, the radiotherapy system includes a medical image collecting device, a body surface data collecting device and processing circuitry. The medical image collecting device collects medical three-dimensional image data of the patient at the time of treatment planning. The body surface data collecting device collects body surface data representing a three-dimensional body surface of the patient at the time of treatment planning. The processing circuitry may generate integrated data in which at least one of the medical three-dimensional image data and the treatment target region data included in the medical three-dimensional image data, and the body surface data are integrated into an identical three-dimensional coordinate system.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: March 15, 2022
    Assignee: Canon Medical Systems Corporation
    Inventor: Satoru Ohishi
  • Patent number: 11277405
    Abstract: Biometric health monitoring of a specific user or population is performed during biometric authentication for granting access to physical or digital assets. If biometric authentication, biometric verification and biometric health monitoring is acceptable, access to the physical or digital assets is allowed. Likewise, if a health anomaly is detected in a specific user or if an outbreak is detected in a specific community, an electronic notification can be sent to the individual, a health administrator, or to a government official, and access may be denied to the specific user.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: March 15, 2022
    Assignee: GLOBAL E-DENTITY, INC.
    Inventors: Robert M. Adams, Jr., Mark Schnitzer, Amanda Adams
  • Patent number: 11266552
    Abstract: Systems and methods for powering a medical imaging machine and a workstation are provided. A vehicle houses the medical imaging machine and workstation. A combustion engine for the vehicle is connected to a generator and a drivetrain for moving said vehicle. One or more electrical panels receive electrical power from said generator and provide a first output at a first voltage to the medical imaging machine and a second output at a second voltage to the workstation controls of the medical imaging machine.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: March 8, 2022
    Inventor: Kenneth L. Guse, III
  • Patent number: 11260245
    Abstract: Systems and methods are provided for radiation delivery. An exemplary method includes receiving an image depicting anatomical data of a target region of patient tissue and determining an initial prescribed dose of radiotherapeutic radiation to be delivered to the target region. The method also includes discretizing the arc for VMAT into a plurality of arc segments and performing an iteration process for determining an arc dose according to radiation delivered in the arc segments. The method further includes determining whether a condition for terminating the iteration process is met and terminating the iteration process based on a result of the determination that the condition for terminating the iteration process is met.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: March 1, 2022
    Assignee: ELEKTA AB (PUBL)
    Inventors: Charis Kontaxis, Gijsbert Herman Bol, Bas Willem Raaymakers
  • Patent number: 11253725
    Abstract: In one embodiment, a method includes receiving treatment information relating to a treatment plan for proton- or ion-beam therapy intended to irradiate a target tissue; receiving machine-limitation information relating to one or more limitations of one or more machines involved in the proton- or ion-beam therapy; determining a time-optimized beam current for a proton or ion beam based on the treatment information and the machine-limitation information, wherein the time-optimized beam current minimizes the time required to deliver a required quantity of monitor units to one of a plurality of spots, wherein each of the plurality of spots is a particular area of the target tissue; and delivering the time-optimized beam current to the particular area.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: February 22, 2022
    Inventors: Holger Goebel, Isabel Huth
  • Patent number: 11246669
    Abstract: A system and method for rapid halt and recovery of motion deviations in a medical device includes a computer-assisted medical device having a first repositionable arm having one or more first repositionable elements, a second repositionable arm having one or more second repositionable elements, and a control unit communicably coupled to the first and second repositionable arms. The control unit is configured to control motion of the first repositionable arm and the first end effector based on a desired motion, monitor an actual motion of the first repositionable arm and the first end effector, determine whether the actual motion deviates from the desired motion by more than a predetermined threshold, and halt motion of the first repositionable arm and the first end effector, or of the second repositionable arm and the second end effector, when the actual motion deviates from the desired motion by more than the predetermined threshold.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: February 15, 2022
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: Goran A. Lynch, Paul G. Griffiths, Michael Turner
  • Patent number: 11247071
    Abstract: Techniques are described herein for delivering a particle beam from a continuously rotating gantry towards a target according to a determined patient state. The determined patient state and an identified gantry angle of a gantry may be used to deliver a set of beamlets (e.g., a pattern of radiation dose) to the target. The particle beam may rotate through a range of gantry angles. The set of beamlets may be delivered continuously while the gantry rotates.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: February 15, 2022
    Assignee: Elekta, Inc.
    Inventor: Stuart Julian Swerdloff
  • Patent number: 11235172
    Abstract: A control circuit carries out various actions to facilitate speedy user interaction involving adjustments to radiation dosing that corresponds to a particular mixed radiation treatment plan. These actions can include remixing particular multi-criteria optimization radiation treatment plans.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: February 1, 2022
    Assignee: Varian Medical Systems, Inc.
    Inventor: Kenneth B. Thornton
  • Patent number: 11226297
    Abstract: A method for determining a total radiation dosage received by an electronic component includes employing a radiation generator to expose the electronic component to an ionizing radiation within a contained environment of an inspection system. The method further includes measuring a total radiation dosage received by the electronic component based on a pre-determined position in the contained environment of the inspection system.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: January 18, 2022
    Assignee: RAYTHEON COMPANY
    Inventors: Mark Northrup, Kevin G. Mohr, Michael T. Booher, James T. Hampton, Jr.
  • Patent number: 11213698
    Abstract: Techniques are described herein for delivering a particle beam from a continuously rotating gantry towards a target according to a determined patient state. The determined patient state and an identified gantry angle of a gantry may be used to deliver a set of beamlets (e.g., a pattern of radiation dose) to the target. The particle beam may rotate through a range of gantry angles. The set of beamlets may be delivered continuously while the gantry rotates.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: January 4, 2022
    Assignee: Elekta, Inc.
    Inventor: Stuart Julian Swerdloff
  • Patent number: 11210804
    Abstract: A method for estimating a 3D map is described. The method includes performing an initialization of a plurality of 3D points in the 3D map based on the plurality of 2D images, reprojecting ones of the 3D points onto ones of the 2D images to obtain reprojection points, determining respective reprojection errors of ones of the reprojection points, determining a robust camera parameter associated with a weighting function based on the respective reprojection errors, and performing bundle adjustment to update the 3D map and update the plurality of poses, based on the robust camera parameter and the weighting function. Related systems, devices and computer program products are also described.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: December 28, 2021
    Assignee: SONY GROUP CORPORATION
    Inventors: Francesco Michielin, Roderick Köehle, Sebastian Farås, Fredrik Mattisson
  • Patent number: 11179129
    Abstract: An apparatus for creating a radiation treatment plan for execution by a radiation treatment machine, includes: a waypoint module configured to obtain imaging waypoint data representing imaging waypoints, the imaging waypoints at least partially defining one or more positions for obtaining images of a patient during a treatment session; a treatment trajectory module configured to obtain treatment data at least partially defining a beam-on direction; a treatment plan generator configured to create the radiation treatment plan based at least in part on the imaging waypoint data and the treatment data.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: November 23, 2021
    Assignee: Varian Medical Systems, Inc.
    Inventors: Adam Scott Harrington, William Kearns, Joakim Olavi Pyyry, Janne I. Nord, Agam Sharda
  • Patent number: 11179128
    Abstract: Methods and systems are provided for medical imaging systems. In one embodiment, a method for a medical imaging system comprises acquiring emission data during a positron emission tomography (PET) scan of a patient, reconstructing a series of live PET images while acquiring the emission data, and tracking motion of the patient during the acquiring based on the series of live PET images. In this way, patient motion during the scan may be identified and compensated for via scan acquisition and/or data processing adjustments, thereby producing a diagnostic PET image with reduced motion artifacts and increased diagnostic quality.
    Type: Grant
    Filed: December 31, 2019
    Date of Patent: November 23, 2021
    Assignee: GE Precision Healthcare LLC
    Inventors: Floribertus P. Heukensfeldt Jansen, Timothy Wayne Deller, Kristen Ann Wangerin, Matthew Spangler-Bickell
  • Patent number: 11179577
    Abstract: Systems and methods are provided for designing and/or modifying a radiation therapy bolus for the reduction of hot spots. A digital bolus model may be modified based on the identification of a peak in the outer surface of the digital bolus model, where the peak satisfies search criteria associated with the generation of a hot spot through scattering from the peak. The digital bolus model is modified within a region surrounding the peak to smooth the peak and thereby reduce the intensity of the hot spot. The modified digital bolus model may be employed to fabricate a bolus for use in radiation therapy. The search criteria may be evaluated according to a proximity between a location measure associated with the peak and a location measure associated with the hot spot, optionally when the location measures are projected in a reference plane that resides perpendicular to the beam axis.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: November 23, 2021
    Assignee: ADAPTIV MEDICAL TECHNOLOGIES INC.
    Inventors: Christopher Majcher, Borko Basaric, James L. Robar
  • Patent number: 11167153
    Abstract: A method of obtaining an interpolated treatment plan is based on interpolating between associated dose distributions through optimization with respect to an optimization problem comprising optimization functions based on deviations from clinical goals. The method may suitably be used to improve navigated plans resulting from multi-criteria optimization.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: November 9, 2021
    Assignee: RaySearch Laboratories AB
    Inventors: Rasmus Bokrantz, Kjell Eriksson, Tianfang Zhang
  • Patent number: 11158408
    Abstract: An apparatus for developing an intensity-modulated radiation therapy treatment plan includes a memory that stores machine instructions and a processor that executes the machine instructions to receive a clinical goal associated with the treatment plan as a user input. The processor further executes the machine instructions to determine a plan objective based on the clinical goal, generate a cost function comprising a term based on the plan objective, and assign an initial value to a parameter associated with the term. The processor also executes the machine instructions to identify a microstate that results in a reduced value associated with the cost function, evaluate a fulfillment level associated with the clinical goal, and adjust the value of the parameter to improve the fulfillment level.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: October 26, 2021
    Assignee: Varian Medical Systems International AG
    Inventors: Esa Kuusela, Lauri Halko
  • Patent number: 11147985
    Abstract: The invention relates to a dynamic sliding-window-like initialization for, for example, iterative VMAT algorithms. Specifically, a dynamic sliding window conversion method is contemplated where typical dynamic VMAT constraints are taken into account to find an optimal set of suitable openings (i.e. binary masks) that can be used as quasi-feasible start initialization for any VMAT algorithm that can refine until a deliverable plan is reached. Here, a multileaf leaf tip trajectory least square constrained optimization is performed to find a set of optimal unidirectional trajectories for all MLC leaf pairs of all arc points. To ensure that a quasi-feasible (or better quasi-deliverable) solution is returned, for example, a maximum dose rate, a maximum gantry speed, a maximum leafs speed, and a maximum treatment time may be enforced.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: October 19, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Alfonso Agatino Isola, Christoph Neukirchen, Torbjoern Vik, Harald Sepp Heese, Rolf Juergen Weese
  • Patent number: 11147988
    Abstract: A dosage verification method for a radiotherapy device includes: acquiring reference optical field information about radioactive rays, wherein the reference optical field information includes the dosage distribution of a reference optical field; acquiring actual optical field information about the radioactive rays; comparing and analyzing the acquired actual optical field information about the radioactive rays and the acquired reference optical field information; and determining whether the actual optical field information is in a range of pre-set optical field information, wherein the pre-set optical field information is optical field information determined according to the reference optical field information.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: October 19, 2021
    Inventors: Jinsheng Li, Haifeng Liu, Hao Yan
  • Patent number: 11147478
    Abstract: A patient monitor is disclosed for detecting patient movement or abnormal breathing. Images of a patient are obtained by a stereoscopic camera. These images are then processed by a 3D position determination module which determines measurements indicative of positions of at least part of a patient. The obtained measurements are then passed to a model generation module which generates a breathing model of the variation in position of the at least part of a patient during a breathing cycle. Subsequently abnormal breathing or patient movement can be detected by processing further images obtained by the stereoscopic camera to determine more measurements indicative of positions of at least part of a patient. These measurements are then compared with a stored breathing model by a comparison module.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: October 19, 2021
    Assignee: VISION RT LIMITED
    Inventors: Ivan Daniel Meir, Norman Ronald Smith, Anthony Christopher Ruto
  • Patent number: 11147989
    Abstract: A method includes detecting a potential setup error in a radiation treatment delivery session of a radiation treatment delivery system, wherein the setup error corresponds to a change in a current position of a treatment target relative to a prior position of the treatment target, and wherein the change includes a rotation relative to the prior position of the treatment target. The method further includes modifying, by a processing device, one or more planned leaf positions of a multileaf collimator (MLC) of a linear accelerator (LINAC) of the radiation treatment delivery system to compensate for the potential setup error corresponding to the rotation of the prior position of the treatment target.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: October 19, 2021
    Assignee: Accuray Incorporated
    Inventors: Andrea Cox, Eric Schnarr
  • Patent number: 11141126
    Abstract: A medical apparatus includes an acquirer, an associator, and a display controller. The acquirer acquires information indicating a respiratory waveform of an object and acquires fluoroscopic images of the object captured in time series. The associator associates a tracking value which fluctuates according to a respiratory phase of the object, based on the time-series fluoroscopic images. The display controller causes a display to display the respiratory waveform and a waveform of the tracking value in a comparable form.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: October 12, 2021
    Assignee: Toshiba Energy Systems & Solutions Corporation
    Inventors: Shinichiro Mori, Koki Yanagawa, Ryusuke Hirai, Shinya Fukushima, Keiko Okaya
  • Patent number: 11141609
    Abstract: Techniques for adjusting radiotherapy treatment for a patient in real-time are provided.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: October 12, 2021
    Assignee: Elekta AB (publ)
    Inventors: David Andreas Tilly, Stella Lucie Riad, Peter Kimstrand, Nina Terese Tilly, Klas Mareks von Würtemberg
  • Patent number: 11141079
    Abstract: Methods and systems are provided for profile-based selection of imaging parameters for a clinical context. In one embodiment, a method comprises selecting a profile based on an indication of clinical context for a scan of a patient, selecting one or more sub-profiles based on the profile, selecting imaging settings for the scan based on the profile and the one or more sub-profiles, and performing the scan according to the selected imaging settings. In this way, a scan prescription may be defined more efficiently and personally for a patient while improving quality assurance and managing an x-ray radiation dose of the patient.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: October 12, 2021
    Assignee: General Electric Company
    Inventors: Franco Rupcich, Chelsey Amanda Lewis, Christine Carol Hammond, Dominic Joseph Crotty, Mark Vincent Profio
  • Patent number: 11141606
    Abstract: A magnetic resonance imaging (MRI) and radiation therapy system is described. The system has a magnet gantry, an MRI apparatus, a patient support system and a radiation source head. The magnet gantry is configured to rotate about a magnet gantry axis. The MRI apparatus is coupled to the magnet gantry. The radiation source head is coupled to the MRI apparatus via a radiation source arm. The radiation source head is configured to emit a treatment beam at varying angles with respect to an azimuthal gantry axis. A method for performing stereotactic radiosurgery (SRS) using a magnetic resonance (MR)-SRS is also described.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: October 12, 2021
    Assignee: ALBERTA HEALTH SERVICES
    Inventors: B. Gino Fallone, Brad Murray, Satyapal Rathee
  • Patent number: 11127173
    Abstract: The invention relates to off-center detector 3D X-ray or proton radiography reconstruction. Redundancy weighting with a steep weighting function around the iso-axis typically leads to artifacts in the reconstruction, for example, if inconsistencies between two nominal redundant projections occur, e.g. due to slightly incorrect detector calibration or scatter correction, etc. With the present invention, an approach is presented for overcoming or mitigating these problems.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: September 21, 2021
    Assignee: KONINKLIJKE PHILIPS N. V.
    Inventors: Dirk Schäfer, Peter George Van De Haar, Sebastien Brousmiche
  • Patent number: 11107203
    Abstract: An image processing method and a display apparatus therefor are provided. The display apparatus includes a display, a communicator that communicates with an external device; a memory storing one or more instructions; and a controller including a processor for executing the one or more instructions stored in the memory. The processor is configured to execute the one or more instructions to receive an image from the external device, obtain information about a first distance corresponding to a distance between a front surface of the display apparatus and a wall, and, when the image is displayed on the display, apply a shadow effect to one or more of sides of the image based on the information about the first distance.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: August 31, 2021
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Yunho Lee, Jaeyoung You, Kwansik Yang
  • Patent number: 11097128
    Abstract: Techniques for generating a radiotherapy treatment plan parameter are provided. The techniques include receiving radiotherapy treatment plan information; processing the radiotherapy treatment plan information to estimate one or more radiotherapy treatment plan parameters based on a process that depends on the output of a subprocess that estimates a derivative of a dose calculation; and generating a radiotherapy treatment plan using the estimated one or more radiotherapy treatment plan parameters.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: August 24, 2021
    Assignee: Elekta AB (publ)
    Inventor: Jens Olof Sjölund
  • Patent number: 11077321
    Abstract: A method and system of controlling a multi-leaf collimator, wherein steps of the method includes: receiving treatment data, and the treatment data includes position information of N treatment points, conformal position information of N treatment points and radiation field shapes of N treatment points; controlling a treatment head to a conformal position of a first treatment point, and controlling the multi-leaf collimator to begin to conform to a radiation field shape of the first treatment point so as to start a treatment of the first treatment point; controlling the treatment head to a conformal position of a Kth treatment point, and controlling the multi-leaf collimator to begin to conform to a radiation field shape of the Kth treatment point so as to start a treatment of the Kth treatment point; carrying out the described operations repeatedly until the conformation of the radiation field shape and the treatment of all treatment points are completed.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: August 3, 2021
    Assignee: OUR UNITED CORPORATION
    Inventors: Jinsheng Li, Mengmeng Zhang
  • Patent number: 11071509
    Abstract: The present invention provides a method, including: obtaining a first image from a first imaging modality; identifying on the first image from the first imaging modality obtaining a second image from a second imaging modality; generating a compatible virtual image from the first image from the first imaging modality; mapping planning data on the compatible virtual image; coarse registering of the second image from the second imaging modality to the first image from the first imaging modality; identifying at least one element of the mapped planning data from the compatible virtual image; identifying at least one corresponding element on the second imaging modality; mapping the at least one corresponding element on the second imaging modality; fine registering of the second image from the second imaging modality to the first image from the first imaging modality; generating a third image.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: July 27, 2021
    Assignee: BODY VISION MEDICAL LTD.
    Inventor: Dorian Averbuch
  • Patent number: 11073628
    Abstract: Timing calibration of a positron emission tomography (PET) imaging device (2) uses a radioactive source (20) comprising a positron-emitting radioisotope having a decay path including emission of two oppositely directed 511 keV gamma rays and a cascade gamma ray at a cascade gamma ray energy. A timestamped radiation detection event data set acquired from the radioactive source by the PET imaging device is processed using energy window filtering (32) and time window filtering (36) to generate a coincidence data set (40, 42, 44) including event pairs (40) each consisting of two coincident 511 keV events and cascade event pairs (42) or triplets (44) each consisting of at least one coincident 511 keV event and a coincident cascade event at the cascade gamma ray energy. A timing calibration (12) is generated using the coincidence data set. The timing calibration comprises offset times for PET detectors of the PET imaging device.
    Type: Grant
    Filed: May 4, 2018
    Date of Patent: July 27, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Leonid Romanov, Andriy Andreyev, Thomas Christoher Bulgrin
  • Patent number: 11071877
    Abstract: A method for generating a radiation treatment plan is provided. The method may include determining a set of one or more optimization goals for radiation delivery by a therapeutic radiation delivery apparatus. The method may also include determining a plan for radiation delivery from a radiation source of the therapeutic radiation delivery apparatus. The radiation source may be capable of continuously rotating around a subject. The plan may include a plurality of radiation segments. Each radiation segment may be characterized by at least one parameter selected from a start angle, a stop angle, a two-dimensional segment shape, or a segment MU value such that the plurality of radiation segments satisfy the set of one or more optimization goals by superimposing at least two radiation segments from at least two different rotations into a target volume of the subject.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: July 27, 2021
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Jingjie Zhou, Li Wang, Cheng Ni, Johannes Stahl, Jonathan Maltz
  • Patent number: 11065473
    Abstract: A method of operating a radiotherapy system mounted on a gantry surrounding a magnetic resonance imaging system is provided, the radiotherapy system comprising a radiotherapy beam generator, and a radiotherapy imaging system, wherein the gantry is arranged to rotate the radiotherapy beam generator around the magnetic resonance imaging system.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: July 20, 2021
    Assignee: Elekta Limited
    Inventor: David Anthony Roberts
  • Patent number: 11065471
    Abstract: Systems and methods for automatic, customized radiation treatment plan generation for cancer are disclosed. According to an aspect, a method includes receiving data indicating anatomy information of a patient and radiation beam characteristics of a radiation therapy system. Further, the method includes determining energy levels for application of radiation beams to the patient.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: July 20, 2021
    Assignees: Duke University, The University of North Carolina at Charlotte
    Inventors: Qingrong Jackie Wu, Yaorong Ge, Taoran Li, Fang-Fang Yin, Yang Sheng
  • Patent number: 11058891
    Abstract: A cloud-based radiation therapy treatment planning system (TPS). The TPS changes the clinical workflow of the radiotherapy treatment planning process, by increasing the mobility and computational power of the treatment planning software and hardware architecture. The system is divided into computational components. A user device includes a light and flexible user interface, while the server side entails a hospital relay server, and/or a graphics processing unit cluster server. The TPS computational architecture enables the computational power of a GPU-cluster server on a tablet, laptop, or smartphone.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: July 13, 2021
    Assignee: Board of Regents, The University of Texas System
    Inventors: Vasant P. Kearney, Ko-ay Timmy Siauw, Xun Jia, Steve Bin Jiang, Xuejun Gu
  • Patent number: 11056243
    Abstract: The present disclosure relates to systems, methods, and computer-readable storage devices for radiotherapy treatment planning. For example, a method may generate a treatment plan for a patient. The method may receive training data reflecting radiotherapy treatment data. The training data may include a feature vector and a target vector. The method may further determine a training model based on the feature vector and the target vector. The method may further receive testing data associated with the patient. The testing data may include a descriptive feature vector. The method may further determine a therapy model based on the descriptive feature vector and the training model. The therapy model may be used to generate the treatment plan.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: July 6, 2021
    Assignee: Elekta AB (Publ)
    Inventor: Jens Olof Sjölund
  • Patent number: 11052264
    Abstract: A robustness optimization is disclosed for a broad beam proton therapy plan. A nominal dose distribution (62) is computed, to be delivered to a volume by performing proton therapy on the volume according to a proton therapy plan (50) having parameters (52) defining a range compensator shape and a range band. The parameters of the proton therapy plan are adjusted to reduce a difference between the nominal dose distribution (62) and a perturbed dose distribution calculated to be delivered to the volume modified by an error scenario (64) by performing proton therapy on the volume modified by the error scenario in accordance with the proton therapy plan with the parameters adjusted by the adjusting operation. The adjusting may be repeated serially for each error scenario of a set of error scenarios (44) to produce a proton therapy plan that is robust for any of these error scenarios.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: July 6, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Vaitheeswaran Ranganathan, Gipson Joe Anto, Murali Balasubramanian, Bojarajan Perumal, Reshmi Bhattacharjee
  • Patent number: 11049627
    Abstract: A radiation treatment delivery system, includes a linear accelerator (LINAC) and a multileaf collimator (MLC), coupled with the distal end of the LINAC, wherein the MLC has two banks of leaves, organized into a plurality of opposing leaf pairs. The system further includes a processing device, operatively coupled to the LINAC and the MLC, to control the plurality of leaf pairs of the MLC such that for each of a plurality of radiation beam delivery positional sections corresponds to a range of radiation beam positions over a discrete time interval that constrains an overall treatment time and wherein each leaf pair of the plurality of opposing leaf pairs is open to a fixed opening for a fraction of time in the discrete time interval and closed for the remaining fraction of time in the discrete time interval, while a radiation beam of the radiation treatment system is active.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: June 29, 2021
    Assignee: ACCURAY INCORPORATED
    Inventors: Eric Schnarr, Hari Gopalakrishnan, Jari Toivanen, Matthew Orton
  • Patent number: 11049252
    Abstract: The moving object tracking apparatus emphasizes an image with specific size in each of fluoroscopic images derived from two or more paired fluoroscopic radiographic devices, obtains a value indicating certainty degree of detecting a candidate position of the object to be tracked on the image subjected to the emphasizing process, extracts the candidate position based on the value indicating the certainty degree of detection, calculates a value indicating a correlation between the candidate position extracted from images picked up from two or more directions, and a position of the fluoroscopic radiation generator, detects the position of the object to be tracked based on the value indicating the certainty degree of detection, and the value indicating the correlation, and controls irradiation of radiation to an irradiation target based on the detected position of the object to be tracked.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: June 29, 2021
    Assignee: HITACHI, LTD.
    Inventors: Koichi Miyazaki, Toru Umekawa, Yusuke Fujii
  • Patent number: 11045666
    Abstract: A particle therapy system includes a particle accelerator for generating a charged particle beam, a beam delivery device, a beam transport system for transporting the beam from the particle accelerator to the beam delivery device, and a supporting device for supporting a subject. The beam delivery device is rotatable around the target and with respect to the supporting device, so as to be able to deliver the beam to the target according to a plurality of irradiation angles. The system also includes a controller configured to make the beam delivery device rotate at a beam-on speed and meanwhile to irradiate the target with the beam. The controller is configured to make the beam delivery device rotate at at least two different beam-on speeds with respect to the supporting device, a first speed corresponding to a first irradiation angle and a second speed corresponding to a second irradiation angle.
    Type: Grant
    Filed: October 16, 2019
    Date of Patent: June 29, 2021
    Assignee: Ion Beam Applications S.A.
    Inventors: Vincent Bossier, Yves Claereboudt, Guillaume Janssens, Olivier De Wilde, David Vangeenberghe
  • Patent number: 11043142
    Abstract: Methods, systems, and computer instructions for virtual radiation oncology training are provided. The methods can allow for screening of many virtual patients in a clinical setting for radiation oncology training. The methods, system, and computer instructions can include receiving a medical record for a virtual patient, presenting the medical record to a trainee, receiving a treatment plan for the virtual patient from the trainee indicating an area to be treated and dose constraints, and computing one or more comparison metrics for the treatment plan.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: June 22, 2021
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Frank J. Bova, Sanford L. Meeks, Twyla R. Willoughby
  • Patent number: 11033331
    Abstract: Provided are a method of controlling motion pattern for a laser treatment and a laser irradiation apparatus using the same, which can perform the efficient laser treatment.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: June 15, 2021
    Assignee: OH & LEE MEDICAL ROBOT, INC.
    Inventors: Yong Soo Lee, Jung Ho Lee, Jung Woo Heo, Jeong Soo Lim
  • Patent number: 11033760
    Abstract: A radiotherapy system and method for delivering radiotherapy are provided. In some aspects, the radiotherapy system includes beam director comprising a radiation source configured to generate radiation for irradiating a patient, the beam director having at least four degrees of freedom of movement. The radiotherapy system also includes a controller configured to operate the beam director to irradiate the patient in accordance with a radiation treatment plan, wherein the radiation treatment plan is generated based on a solution space determined by the at least four degrees of freedom of movement of the beam director.
    Type: Grant
    Filed: March 24, 2018
    Date of Patent: June 15, 2021
    Assignees: The Regents of the University of California, Radiabeam Systems, LLC
    Inventors: Ke Sheng, Salime M. Boucher