Therapy Patents (Class 378/65)
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Patent number: 10940330Abstract: A method of calculating radiation dose includes dosimetric projection of a collimator geometry. The method includes defining a three-dimensional (3D) geometry of a collimating device which defines an aperture configured to allow a radiation beam passing through, projecting the collimating device along the radiation beam into a two-dimensional (2D) geometry in a plane, calculating dosimetric opacity values of the collimating device at locations adjacent to the aperture based on the 3D geometry of the collimating device, and calculating transport of the radiation beam through the collimating device based on the 2D geometry projected in the plane and using the dosimetric opacity values of the collimating device at the locations adjacent to the aperture.Type: GrantFiled: March 20, 2019Date of Patent: March 9, 2021Assignee: VARIAN MEDICAL SYSTEMS INTERNATIONAL AGInventors: Timo Ikonen, Christopher Boylan, Ari Harju, Petri Hiltunen, Juha Kauppinen, Petri Kokkonen, Viljo Petaja, Marko T Rusanen, Sami P Siljamaki, Tuomas E Torsti, Esa Kuusela, Antti Karjalainen
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Patent number: 10932732Abstract: Provided is a radiation shielding device according to various embodiments. The radiation shielding device includes: a body structure forming a receiving space receiving a user's body part, wherein a through passage penetrating an inside of the body structure is formed in the body structure; a shielding unit positioned to reciprocatively move along the through passage, wherein a shielding pad configured to shield the radiation is included in a portion of the shielding unit; and a driver configured to transfer a driving force to the shielding unit to cause the shielding unit to reciprocatively move.Type: GrantFiled: October 12, 2017Date of Patent: March 2, 2021Assignee: Samsung Life Public Welfare FoundationInventors: Sang Hun Kim, Sung Ryong Kim, Pyoung Jeon, Won Hong Cho
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Patent number: 10926106Abstract: A method and system supports pre-positioning a patient for treatment by radiotherapy or radiosurgery. The disclosed method encompasses comparing an image of a reference structure having a known position relative to an anatomical body part of a patient, such as a live thermal/infrared image of the reference structure, to a predetermined medical image of the reference structure associated with a known position relative to a reference position, such as a known isocenter of a radiotherapy or radiosurgery apparatus. On that basis, it is determined whether the reference structure has moved relative to the reference position. A decision may be made to determine whether the reference structure and therefore the patient has been correctly positioned and/or kept in his desired position relative to a treatment device, and to compensate for any possible positional deviation by moving the patient.Type: GrantFiled: May 4, 2016Date of Patent: February 23, 2021Assignee: BRAINLAB AGInventors: Kajetan Berlinger, Hagen Kaiser
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Patent number: 10929976Abstract: A method and apparatus for assessing image registration. The method comprises obtaining image datasets for the first and second medical images and registration data representing the registration from the first medical image to the second medical image, collating use-case information for the image registration, deriving a set of at least one measurement and assessment criteria therefor based at least partly on the collated use-case information, performing the at least one measurement on at least one of the obtained image datasets and the obtained registration data to derive at least one measurement value, applying the assessment criteria for the at least one measurement to the at least one measurement value to derive at least one assessment result, and outputting an indication of the at least one assessment result.Type: GrantFiled: February 23, 2016Date of Patent: February 23, 2021Assignee: Mirada Medical Limited, LLCInventors: Mark Gooding, Timor Kadir
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Patent number: 10929990Abstract: There are provided a registration apparatus, method, and program capable of performing high-speed registration between three-dimensional images included in imaging series included in different examinations. An accessory information acquisition unit acquires, from each of two examinations including a plurality of imaging series including three-dimensional images each of which is configured to include a plurality of tomographic images, accessory information regarding the three-dimensional images. A series selection unit selects one imaging series from each of the two examinations based on the accessory information. A registration unit performs registration between the three-dimensional images included in the imaging series of the two examinations based on images included in the selected imaging series and acquires a result of the registration as a registration result between the two examinations.Type: GrantFiled: September 11, 2018Date of Patent: February 23, 2021Assignee: FUJIFILM CorporationInventor: Ryoji Sasada
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Patent number: 10922856Abstract: A method for correcting projection images in CT image reconstruction is provided. The method may include obtaining a plurality of projection images of a subject. Each of the plurality of projection images may correspond to one of the plurality of gantry angles. The method may further include correcting a first projection image of the plurality of projection images according to a process for generating a corrected projection image. The process may include performing, based on the first projection image and a second projection image of the plurality of projection images, a first correction on the first projection image to generate a preliminary corrected first projection image. The process may also include performing, based on at least part of the preliminary corrected first projection image, a second correction on the preliminary corrected first projection image to generate a corrected first projection image corresponding to the first gantry angle.Type: GrantFiled: January 21, 2019Date of Patent: February 16, 2021Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Hongcheng Yang, Jianwei Zhu, Haining Sun, Jonathan Maltz
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Patent number: 10912951Abstract: A radiation-treatment plan that comprises a plurality of dose-delivery fractions can be optimized by using fraction dose objectives and at least one other, different dose objective. This use of fraction dose objectives can comprise accumulating doses delivered in previous dose-delivery fractions. The other, different dose objective can comprise a remaining total dose objective, a predictive dose objective, or some other dose objective of choice. An existing radiation-treatment plan having a corresponding resultant quality and that is defined, at least in part, by at least one delivery parameter can be re-optimized by specifying at least one constraint as regards that delivery parameter as a function, at least in part, of that resultant quality and then applying that constraint when re-optimizing the existing radiation-treatment plan.Type: GrantFiled: February 18, 2020Date of Patent: February 9, 2021Assignee: Varian Medical Systems International AGInventors: Janne I. Nord, Jarkko Y. Peltola, Juha Kauppinen
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Patent number: 10898158Abstract: A phantom setup and source-to-surface distance (SSD) verification method uses radiation images. In an exemplary method, a phantom is positioned on a support relative to a radiation source such that a surface of the phantom is horizontally leveled at or approximate to a desired value of SSD. The radiation source is then positioned at a gantry angle predetermined at least based on the desired value of SSD such that a ray of radiation from the radiation source aligns with a horizontal surface located at the desired value of SSD. An image is acquired using radiation from the radiation source at the predetermined gantry angle. Verification is performed to confirm, based on an analysis of the image, if the surface of the phantom is positioned at the desired value of SSD.Type: GrantFiled: May 11, 2017Date of Patent: January 26, 2021Assignee: Varian Medical Systems, Inc.Inventors: Magdalena Constantin, HsinLu Hsu
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Patent number: 10898730Abstract: In various embodiments, a radiation therapy method can include loading a planning image of a target in a human. In addition, the position of the target can be monitored. A computation can be made of an occurrence of substantial alignment between the position of the target and the target of the planning image. Furthermore, after the computing, a beam of radiation is triggered to deliver a dosage to the target in a short period of time (e.g., less than a second).Type: GrantFiled: December 31, 2018Date of Patent: January 26, 2021Assignees: Varian Medical Systems International AG, Varian Medical Systems, IncInventors: Christel Smith, Corey Zankowski, Jan Timmer, Wolfgang Kaissl, Deepak Khuntia, Eric Abel, Josh Star-Lack, Camille Noel
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Patent number: 10894315Abstract: A robot controller comprising a processor that is configured to execute computer-executable instructions so as to controls a robot including an arm capable of moving at least one of a target object and a discharger capable of discharging a discharge object to the target object, wherein the processor is configured to use a first position based on a jig removably attached to the discharger to generate teaching information on a position of the arm.Type: GrantFiled: May 21, 2018Date of Patent: January 19, 2021Inventors: Yoshito Miyamoto, Tsuguya Kojima, Toshiyuki Ishigaki
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Patent number: 10888714Abstract: Magnetic resonance (MR) guided radiation therapy (MRgRT) enables control over the delivery of radiation based on patient motion indicated by MR imaging (MRI) images captured during radiation delivery. A method for MRgRT includes: simultaneously using one or more radiation therapy heads to deliver radiation and an MRI system to perform MRI; using a processor to determine whether one or more gates are triggered based on at least a portion of MRI images captured during the delivery of radiation; and in response to determining that one or more gates are triggered based on at least a portion of the MRI images captured during the delivery of radiation, suspending the delivery of radiation.Type: GrantFiled: October 22, 2018Date of Patent: January 12, 2021Assignee: VIEWRAY TECHNOLOGIES, INC.Inventors: James F. Dempsey, Iwan Kawrykow
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Patent number: 10881877Abstract: An apparatus includes: a processor configured for obtaining a first image that corresponds with a first multi-leaf collimator (MLC) configuration, wherein the first image is generated when the MLC is stationary, obtaining a second image that corresponds with a second MLC configuration, wherein the second image is generated when the MLC and/or another component of a radiation machine is being operated to track a motion, and performing an analysis based at least in part on the first image and the second image to obtain a result; and a non-transitory medium for storing the result.Type: GrantFiled: April 12, 2018Date of Patent: January 5, 2021Inventors: Stefan G. Scheib, Christof Baltes, Kristijan Macek
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Patent number: 10881875Abstract: An achievability estimate is computed for an intensity modulated radiation therapy (IMRT) geometry (32) including a target volume, an organ at risk (OAR), and at least one radiation beam. Namely, a geometric complexity (GC) metric is computed for the IMRT geometry that compares a number NT of beamlets of the at least one radiation beam available in the IMRT geometry for irradiating the target volume and a number n of these beamlets that also pass through the OAR. A GC metric ratio is computed of the GC metric for the IMRT geometry and the GC metric for a reference IMRT geometry for which an IMRT plan is achievable. If the clinician is satisfied with this estimate then optimization (38) of an IMRT plan for the IMRT geometry (32) is performed. Alternatively, a reference IMRT geometry is selected by comparing the GC metric with GC metrics of past IMRT plans.Type: GrantFiled: March 1, 2017Date of Patent: January 5, 2021Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Vaitheeswaran Ranganathan, Prashant Kumar, Karl Antonin Bzdusek
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Patent number: 10886026Abstract: This disclosure relates generally to treatment management systems, which may include a clinical database for storing therapeutic protocols. The system may also include a treatment engine operatively connected to the clinical database. The treatment engine may obtain diagnostic information and select a first plurality of therapeutic protocols from the clinical database based on the obtained diagnostic information and reference protocol data. The treatment engine may calculate a treatment efficacy probability for each protocol using the reference protocol data. The treatment engine may develop a first treatment plan and evaluate intermediate data indicating an altered patient state due to the first treatment plan. The treatment engine may select, based on reference protocol data and adaptive protocol data, a second treatment plan using a second plurality of therapeutic protocols.Type: GrantFiled: March 10, 2016Date of Patent: January 5, 2021Assignee: Elekta, Inc.Inventors: Johannes Ferdinand Van Der Koijk, Scot Evan Hogan, Colin Raymond Winfield, Alexis Nicolaas Thomas Jozef Kotte
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Patent number: 10881880Abstract: A computer program product, method, system and device that acquires, by a radiation detector, exit radiation measurement information during delivery of patient treatment. Patient anatomy information is also received and a radiation detector response calibration is determined utilizing at least the exit radiation measurement information, the patient anatomy information, and at least a portion of a radiation treatment plan.Type: GrantFiled: April 10, 2020Date of Patent: January 5, 2021Assignee: SUN NUCLEAR CORPORATIONInventors: Amir Ramezanzadeh Moghadam, Jakub Kozelka
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Patent number: 10881876Abstract: The present disclosure provides a radiation method for radiating a fluence map having a zero-fluence region under a movement of MLC (Multi-Leaf Collimator) includes a determining step of determining at least one basic fluence map from the fluence map. The basic fluence map includes a first non-zero fluence region and a second non-fluence region having the zero-fluence region therebetween. The radiation method includes a first radiating step including radiating the first non-zero fluence region, along with moving a first group of leaf pairs and moving a vertical jaw to shade the first group of leaf pairs, and a second radiating step including radiating the second non-zero fluence region, along with moving a second group of leaf pairs and withdrawing the vertical jaw to expose the second group of leaf pairs.Type: GrantFiled: June 6, 2019Date of Patent: January 5, 2021Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventor: Weiyuan Wang
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Patent number: 10863946Abstract: In nuclear medical imaging, respiratory motion is corrected. Rather than pairwise estimation of motion from projection views, a sequence-based technique is used to jointly estimate parameters for a motion model across many projection views. In one approach, this sequence-based method is iteratively solved with a maximum likelihood objective function incorporating the motion model. A surrogate respiration signal is used to gate for the joint estimation and used to convert gated motion parameters to temporal motion parameters.Type: GrantFiled: July 17, 2019Date of Patent: December 15, 2020Assignee: Siemens Medical Solutions USA, Inc.Inventors: James Chester Sanders, III, Alexander Hans Vija
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Patent number: 10857384Abstract: Streamlined and partially automated methods of setting normal tissue objectives in radiation treatment planning are provided. These methods may be applied to multiple-target cases as well as single-target cases. The methods can impose one or more target-specific dose falloff constraints around each target, taking into account geometric characteristics of each target such as target volume and shape. In some embodiments, methods can also take into account a planner's preferences for target dose homogeneity. In some embodiments, methods can generate additional dose falloff constraints in locations between two targets where dose bridging is likely to occur.Type: GrantFiled: October 17, 2018Date of Patent: December 8, 2020Assignee: Varian Medical Systems International AGInventors: Santtu Ollila, Mikko Vainio, Jarkko Peltola, Janne Nord
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Patent number: 10857392Abstract: To overcome the difficulties inherent in conventional proton therapy systems, new techniques are described herein for synchronizing the application of proton radiation with the periodic movement of a target area. In an embodiment, a method is provided that combines multiple rescans of a spot scanning proton beam while monitoring the periodic motion of the target area, and aligning the applications of the proton beam with parameters of the periodic motion. For example, the direction(s) and frequency of the periodic motion may be monitored, and the timing, dose rate, and/or scanning direction and spot sequence of the beam can be adjusted to align with phases in the periodic motion.Type: GrantFiled: October 17, 2017Date of Patent: December 8, 2020Assignees: Varian Medical Systems, Inc., Varian Medical Systems Particle Therapy GmbHInventors: Markus Bach, Isabel Huth, Juergen Heese, Franko Piskulich, Lei Dong
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Patent number: 10857391Abstract: A method may include acquiring a first image including a target point and a first reference point, the target point corresponding to at least one part of a subject, the first reference point corresponding to a first marker disposed on the couch of the medical device; determining a first spatial position of the first marker, the first spatial position corresponding to a first working position of the couch; determining a first spatial position of the at least one part of the subject based on the first image and the first spatial position of the first marker; determining a second spatial position of the first marker, the second spatial position corresponding to a second working position of the couch; determining a second spatial position of the at least one part of the subject based on the second spatial position of the first marker and the first spatial position of the at least one part of the subject.Type: GrantFiled: December 12, 2018Date of Patent: December 8, 2020Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Johannes N Stahl, Supratik Bose, Li Wang
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Patent number: 10850120Abstract: A clinical goal for radiation treatment of a patient is set. A dose prediction model is selected from a number of dose prediction models based on the clinical goal. A radiation treatment plan is then generated for the patient using the dose prediction model that was selected based on the clinical goal.Type: GrantFiled: December 27, 2016Date of Patent: December 1, 2020Assignee: Varian Medical Systems International AGInventors: Hannu Laaksonen, Esa Kuusela, Janne Nord, Joakim Pyyry, Perttu Niemela
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Patent number: 10854339Abstract: Systems and methods are disclosed for associating medical images with a patient. One method includes: receiving two or more medical images of patient anatomy in an electronic storage medium; generating an anatomical model for each of the received medical images; comparing the generated anatomical models; determining a score assessing the likelihood that the two or more medical images belong to the same patient, using the comparison of the generated anatomical models; and outputting the score to an electronic storage medium or display.Type: GrantFiled: April 10, 2019Date of Patent: December 1, 2020Assignee: HeartFlow, Inc.Inventors: Leo Grady, Christopher K. Zarins, Edward Karl Hahn, III, Ying Bai, Sethuraman Sankaran, Peter Kersten Petersen, Michiel Schaap
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Patent number: 10850124Abstract: Radiation treatment planning includes accessing values of parameters such as a number of beams to be directed into sub-volumes in a target, beam directions, and beam energies. Information that specifies limits for the radiation treatment plan are accessed. The limits include a limit on irradiation time for each sub-volume outside the target. Other limits can include a limit on irradiation time for each sub-volume in the target, a limit on dose rate for each sub-volume in the target, and a limit on dose rate for each sub-volume outside the target. The values of the parameters are adjusted until the irradiation time for each sub-volume outside the target satisfies the maximum limit on irradiation time.Type: GrantFiled: September 28, 2018Date of Patent: December 1, 2020Assignees: Varian Medical Systems International, AG, Varian Medical Systems, Inc.Inventors: Reynald Vanderstraeten, Eric Abel, Christel Smith, Anthony Magliari, Timo Koponen, Stanley Mansfield, Charles Adelsheim
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Patent number: 10842456Abstract: A method for determining an alignment between at least two bone parts of an elongated bone system of a patient includes recording a plurality of partially spatially overlapping projection images by a recording system of an x-ray device during a translational movement of the x-ray device or the recording system in a direction of or parallel to a longitudinal axis of the bone system. Tomosynthesis image data of the bone parts is reconstructed from the recorded projection images, and an alignment angle between the at least two bone parts is determined or estimated at least partially based on the reconstructed tomosynthesis image data and/or the plurality of projection images.Type: GrantFiled: October 17, 2018Date of Patent: November 24, 2020Assignee: Siemens Healthcare GmbHInventors: Alexander Gemmel, Gerhard Kleinszig, Björn Kreher, Benedict Swartman, Wei Wei, Markus Weiten, Qiao Yang
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Patent number: 10835764Abstract: A function/process of recording marker position data and spot data is provided. The marker position data includes position information of a marker 29 measured for tumor tracking irradiation and information on time of execution of X-ray imaging. The spot data includes information on time of irradiation of each spot, a delivered irradiation position, and a delivered irradiation amount. The marker position data and the spot data are synchronized based on the time information, and by using the marker position data and the spot data upon spot irradiation, a delivered dose distribution of proton irradiation is calculated. With this configuration, it is possible to take the influence of interplay effect into consideration, and it is possible to support to make more appropriate determination upon replanning of a treatment plan.Type: GrantFiled: March 23, 2017Date of Patent: November 17, 2020Assignees: HITACHI, LTD., NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITYInventors: Yusuke Fujii, Taeko Matsuura, Yuka Matsuzaki, Kikuo Umegaki, Hiroki Shirato, Hidenori Koyano, Takahiro Yamada, Rintarou Fujimoto
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Patent number: 10838077Abstract: A device for determining an ionizing radiation dose deposited by a medical imaging apparatus during a radiological examination of a patient includes at least one measurement probe comprising at least one optical probe defining two exit ends, the optical probe comprising at least one active section made from a scintillator and intended to emit photons under the effect of incident ionizing radiation and at least two transport sections that are placed on either side of the active section and configured to transport the photons emitted by the active section to the exit ends; at least one detection system comprising at least two photodetectors, each photodetector being connected to one respective exit end of the optical probe to receive and count the photons received from the exit end; and at least one processing module configured to determine the deposited dose on the basis of the measurements carried out by the photodetectors.Type: GrantFiled: July 6, 2017Date of Patent: November 17, 2020Assignee: FibermetrixInventors: Mèlodie Munier, Till Sohier, Fayçal Torche, Fanny Carbillet
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Patent number: 10824925Abstract: Implantable transponders comprising no ferromagnetic parts for use in medical implants are disclosed herein. Such transponders may assist in preventing interference of transponders with medical imaging technologies. Such transponders may optionally be of a small size, and may assist in collecting and transmitting data and information regarding implanted medical devices. Methods of using such transponders, readers for detecting such transponders, and methods for using such readers are also described.Type: GrantFiled: December 4, 2018Date of Patent: November 3, 2020Assignee: Establishment Labs S.A.Inventors: Randolph Keith Geissler, Rudy A. Mazzocchi, Juan José Chacón Quirós, Steven A. Lewis
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Patent number: 10825639Abstract: An x-ray device is for creation of high-energy x-ray radiation. In an embodiment, the x-ray device includes a linear accelerator. The linear accelerator, for creation of x-ray radiation, is embodied so as to create an electron beam directed onto a target, of which the kinetic energy per electron amounts to at least 1 MeV. In an embodiment, the x-ray device further includes a beam limiting device, arranged in the beam path of the electron beam between linear accelerator and the target, including an edge region surrounding a beam limiting device opening. A material thickness of the edge region, in a propagation direction of the accelerated electron beam emerging from the linear accelerator, amounting to less than 10% of the average reach of electrons of the created kinetic energy in the material of the edge region.Type: GrantFiled: April 9, 2018Date of Patent: November 3, 2020Assignee: SIEMENS HEALTHCARE GMBHInventors: Martin Koschmieder, Marvin Moeller, Sven Mueller, Stefan Willing
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Patent number: 10814143Abstract: A database stores pre-calculated solutions each of which defines a radiation therapy treatment plan for a treatment volume associated with at least one target and at least one organ-at-risk. The pre-calculated solutions are divided into at least two groups each of which includes at least one pre-calculated solution. The pre-calculated solutions in a given group represent radiation therapy treatment plans which share a common beam configuration. A radiation therapy treatment plan (sc) is established based on the pre-calculated solutions as follows. A first user interface receives operator commands specifying criteria for selecting radiation therapy treatment plans from the database, the criteria defining a set of parameters for the treatment volume. In particular, the operator commands jointly specify criteria for selecting radiation therapy treatment plans from more than one of the at least two groups.Type: GrantFiled: March 30, 2016Date of Patent: October 27, 2020Assignee: RaySearch Laboratories ABInventor: Björn Hårdemark
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Patent number: 10792513Abstract: A radiation therapy treatment method includes providing a patient model, dosimetric constraints, delivery motion constraints, and delivery coordinate space of a radiation delivery device, where the delivery coordinate space is represented as a mesh with vertices connected by edges, where the vertices correspond to directions of a beam eye view (BEV) of the radiation delivery device. BEV region connectivity manifolds are constructed from the patient model, the dosimetric constraints, the delivery coordinate space, and existing beam trajectories, wherein each of the BEV region connectivity manifolds represents connections between contiguous 2D target regions. Beam trajectories are selected based on region connectedness information in the BEV region connectivity manifolds, the dosimetric constraints, the delivery motion constraints, and the existing beam trajectories. Radiation is delivered using the radiation delivery device in accordance with the selected beam trajectories.Type: GrantFiled: March 2, 2020Date of Patent: October 6, 2020Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Karl Bush, Michael J. Hadsell, Christopher Locke, Lei Xing
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Patent number: 10780297Abstract: Disclosed is a method for determining a positional pattern of an irradiation unit for irradiating a patient with treatment radiation. Optimal order data describing an order of the irradiation unit positions for which the statistical value is optimal is determined. The optimal order data is determined based on irradiation unit position data describing irradiation unit positions of the irradiation unit for which the imaging device has a free viewing direction onto the position of the patient, position orders data describing all possible orders of the irradiation unit positions for which the imaging device has a free viewing direction onto the position of the patient, and intersection angle data describing a statistical quantity of the intersection angles between free viewing directions of the imaging unit for irradiation unit positions which are immediately subsequent in the order described by the position orders data.Type: GrantFiled: February 10, 2017Date of Patent: September 22, 2020Assignee: BRAINLAB AGInventors: Kajetan Berlinger, Hagen Kaiser
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Patent number: 10773101Abstract: Methods are provided for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject. One such method comprises: determining a dose modification voxel for which it is desired to modify the dose value and a corresponding magnitude of desired dose modification; for each of a plurality of beams: (i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing the projection of the beamlet into space; and (ii) identifying one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel; modifying the intensity values of at least one of the dose-change beamlets; and updating the achievable dose distribution estimate to account for the modified intensity values of the at least one of the dose-change beamlets.Type: GrantFiled: July 9, 2018Date of Patent: September 15, 2020Assignee: Varian Medical Systems International AGInventor: Karl Otto
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Patent number: 10765888Abstract: The present disclosure relates to systems, methods, and computer-readable storage media for radiotherapy. Embodiments of the present disclosure may receive a plurality of training data and determine one or more predictive models based on the training data. The one or more predictive models may be determined based on at least one of a conditional probability density associated with a selected output characteristic given one or more selected input variables or a joint probability density. Embodiments of the present disclosure may also receive patient specific testing data. In addition, embodiments of the present disclosure may predict a probability density associated with a characteristic output based on the one or more predictive models and the patient specific testing data. Moreover, embodiments of the present disclosure may generate a new treatment plan based on the prediction and may use the new treatment plan to validate a previous treatment plan.Type: GrantFiled: July 6, 2018Date of Patent: September 8, 2020Assignees: Elekta AB, Elekta, Inc.Inventors: Jens Olof Sjolund, Xiao Han
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Patent number: 10751546Abstract: Provided are a radiation treatment planning system and a radiation treatment system that are capable of achieving time shortening and labor saving of treatment planning making when a radiation treatment is planned. A predicted DVH calculation portion 4034 of an arithmetic processing device 403 in a radiation treatment planning system 400 anisotropically enlarges a target region 501 in an irradiated body image which is input to the radiation treatment planning system 400, and calculates an overlap volume OV with an organ-at-risk region 502 per the number of times of enlargement. A DVH (Dose Volume Histogram) is predicted from a volume of the calculated OV, and a dose histogram in the OV per the number of times of enlargement which is calculated from a past treatment planning data group, and is displayed on a display device 401.Type: GrantFiled: November 7, 2017Date of Patent: August 25, 2020Assignees: HITACHI, LTD., NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITYInventors: Taisuke Takayanagi, Toru Umekawa, Shinichiro Fujitaka, Seishin Takao
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Patent number: 10751550Abstract: A system for delivering radiation dose, includes a gantry to move about a target to be irradiated and a radiation source mounted to the gantry and directed inward toward the target, The system further includes a collimator mounted to the gantry and in front of the radiation source, the collimator to shape a radiation beam directed at the target, wherein the collimator is to modulate a sub-beam intensity of the radiation beam across a plurality of sub-beams that subdivide a fluence field into a two-dimensional (2D) grid, and wherein a plurality of independent two-dimensional (2D) sub-beam intensity patterns are delivered from a plurality of gantry angles while the gantry moves continuously.Type: GrantFiled: August 6, 2018Date of Patent: August 25, 2020Assignee: ACCURAY INCORPORATEDInventors: Eric Schnarr, Robert O'Connell, Richard Nash, Matthew Orton, Jacob Shea
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Patent number: 10737118Abstract: A method of monitoring a patient includes: obtaining an input image having a plurality of regions of interest by a processing unit; and determining a plurality of positions for the respective plurality of regions of interest by the processing unit; wherein the act of determining the plurality of positions comprises: accessing a plurality of templates; comparing the plurality of templates with respective areas in the input image using a comparator in the processing unit; and determining the plurality of positions based at least in part on a result of the act of comparing.Type: GrantFiled: March 3, 2015Date of Patent: August 11, 2020Assignee: Varian Medical Systems, Inc.Inventor: Hassan Mostafavi
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Patent number: 10737114Abstract: A method and system are provided for converting clinical criteria constraints for a target structure of radiation therapy into a second set of constraints. The method includes selecting, by a hardware processor, a plurality of clusters of voxels in the target structure based on pre-specified criteria. The method further includes assigning, by the hardware processor, each of the plurality of clusters of voxels a respective constraint that specifies one or more bounds on a radiation dose applied to each voxel in a corresponding one of the plurality of clusters of voxels. The method also includes storing, in a memory device, the respective constraint for each of the plurality of clusters of voxels.Type: GrantFiled: December 6, 2016Date of Patent: August 11, 2020Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Anne E. Gattiker, Sani R. Nassif, Tom Osiecki, Chin Ngai Sze
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Patent number: 10737116Abstract: When reducing radiation dose to healthy tissue near a target volume, a 4D motion model (52) of a target volume is generated during CT scan data acquisition. The target volume is tracked, and tracked target volume position information (43) is provided to a motion estimation tool (48). Motion parameter information (60) output from the motion estimation tool is linked to motion phases of the target volume indicated by CT scan data. A dynamic planned target volume (PTV) (64) that covers the target volume in each motion phase is generated and linked to tracked motion parameters for each respective motion phase. A radiation dose is delivered to the PTV for each motion phase using the linked motion parameters and real-time tracking information.Type: GrantFiled: July 29, 2014Date of Patent: August 11, 2020Assignees: KONINKLIJKE PHILIPS N.V., BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Shyam Bharat, Sankara Hari Gopalakrishnan, Amit Ramakant Sawant
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Patent number: 10734118Abstract: Embodiments develop a predictive dose-volume relationships for a radiation therapy treatment is provided. A system includes a memory area for storing data corresponding to a plurality of patients, wherein the data comprises a three-dimensional representation of the planning target volume and one or more organs-at-risk. The data further comprises an amount of radiation delivered to the planning target volume and the one or more organs-at-risk. The system further includes one or more processors programmed to access, from the memory area, the data and to develop a model that predicts dose-volume relationships using the three-dimensional representations of the planning target volume and the one or more organs-at-risk. The model is being derived from correlations between dose-volume relationships and calculated minimum distance vectors between discrete volume elements of the one or more organs-at-risk and a boundary surface of the planning target volume.Type: GrantFiled: May 12, 2017Date of Patent: August 4, 2020Assignee: Washington UniversityInventors: Kevin L. Moore, Sasa Mutic, Ryan Scott Brame, Lindsey Appenzoller
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Patent number: 10735427Abstract: An electronic device and a program management method therefor are provided. The electronic device includes a communication interface, a memory, at least one processor, and a secure circuitry. The secure circuitry is configured to provide a first public key stored in the secure circuitry to the at least one processor. The at least one processor is configured to transmit the first public key to an external device and receive an encrypted secure program encrypted based on the first public key and a second public key generated by the external device, from the external device. The at least one processor is further configured to transmit the second public key and the encrypted secure program to the secure circuitry. The secure circuitry is configured to decrypt the encrypted secure program based on the second public key and a first private key which is symmetrical to the first public key.Type: GrantFiled: November 24, 2017Date of Patent: August 4, 2020Assignee: Samsung Electronics Co., Ltd.Inventors: Eun Young Kwon, Yang Keun Kim, Jong Su Kim, Taeck Ki Lee, Dae Haeng Cho, Chol Seo Park, Da Som Lee
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Patent number: 10722733Abstract: A positioning apparatus and a positioning method has a control element and function 40 includes a radiograph acquisition element 41 that acquires radiograph data detected by two radiography systems selected from a group consisting of a flat panel detector, a DRR (Digital Reconstructed Radiograph) generation element 42 that generates DRR in two different directions by virtually performing fluoroscopic projection relative to the 3-dimensional CT data obtained through the network 17, a positioning element 43 that positions a CT to the X-ray fluoroscopic radiograph obtained from two radiography systems, and a displacement distance calculation element 44 that calculates a displacement distance of the tabletop 31 based on the gap between radiographs for improved positioning.Type: GrantFiled: March 30, 2017Date of Patent: July 28, 2020Assignee: SHIMADZU CORPORATIONInventor: Wataru Takahashi
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Patent number: 10722731Abstract: A system and method for adapting treatment plan are provided. The method may include: obtaining a planning image of a region of interest relating to a first treatment fraction of a first treatment plan; obtaining a first image of the region of interest relating to a first scan of the region of interest with a first dose level; comparing the planning image with the first image to generate a first comparison result; determining whether the first comparison result satisfies a first replanning condition; causing, in response to a determination that the first comparison result satisfies the first replanning condition, one or more scanners to perform a second scan with a second dose level to provide a second image; and generating a second treatment plan according to the second image, wherein the second dose level is higher than the first dose level.Type: GrantFiled: September 30, 2017Date of Patent: July 28, 2020Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventor: Jonathan S. Maltz
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Patent number: 10716496Abstract: A data processing method performed by a computer for determining breathing signal data which represents a breathing cycle of a patient, comprising the steps of: —acquiring image data representing a sequence of training thermal images of at least a part of the surface of the patient's body over time, the sequence covering at least one half breathing cycle and being captured by a thermographic camera; and —tracking at least one tracked point in the image data over the sequence of training thermal images to find a trajectory of the tracked point as the breathing signal data, wherein the tracked point is a point on the surface of the patient's body.Type: GrantFiled: April 28, 2015Date of Patent: July 21, 2020Assignee: BRAINLAB AGInventors: Hagen Kaiser, Kajetan Berlinger
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Patent number: 10716954Abstract: In one embodiment, a method includes receiving treatment information relating to a treatment plan for proton- or ion-beam therapy intended to irradiate a target tissue; receiving machine-limitation information relating to one or more limitations of one or more machines involved in the proton- or ion-beam therapy; determining a time-optimized beam current for a proton or ion beam based on the treatment information and the machine-limitation information, wherein the time-optimized beam current minimizes the time required to deliver a required quantity of monitor units to one of a plurality of spots, wherein each of the plurality of spots is a particular area of the target tissue; and delivering the time-optimized beam current to the particular area.Type: GrantFiled: April 4, 2017Date of Patent: July 21, 2020Assignee: Varian Medical System Particle Therapy GmbHInventors: Holger Goebel, Isabel Huth
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Patent number: 10709610Abstract: Systems and methods for performing laser cataract surgery, for using a biometric system to determine a material property of a structure of the eye, laser pulses in a laser shot pattern having different powers. A therapeutic laser, and laser delivery system having the capability to vary the power of the laser beam.Type: GrantFiled: April 15, 2016Date of Patent: July 14, 2020Assignee: Lensar, Inc.Inventors: Dustin Morley, Gary P. Gray, Richard Ty Olmstead
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Patent number: 10709905Abstract: Applicant presents an improved manner of modeling and calculating the tongue-and-groove effect in multi-leaf collimators in treatment planning systems and processes. The method is based on subtracting an individualized profile area that is determined for each individual model of MLC. The method also includes how to easily obtain the shape of this non-constant profile based on the tests. The method provides better accuracy, particularly for plans using small MLC gaps.Type: GrantFiled: June 29, 2018Date of Patent: July 14, 2020Inventor: Victor Hernandez
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Patent number: 10702708Abstract: A radiation-treatment plan to treat a treatment target in a given patient takes into account imaging-based dosing of that patient by, for example, automatically accounting for radiation dosing of the given patient that results from imaging to determine at least one physical position of the given patient when forming the radiation-treatment plan. These teachings are particularly beneficial when applied in application settings where the aforementioned imaging comprises obtaining images using megavoltage-sourced radiation. By one approach these teachings provide for automatically accounting for radiation dosing of the given patient that results from imaging by, at least in part, automatically adjusting therapeutic dosing of the given patient as a function of the radiation dosing of the given patient that results from such imaging.Type: GrantFiled: September 25, 2015Date of Patent: July 7, 2020Assignees: Varian Medical Systems, Inc., Varian Medical Systems International AGInventors: Mika Miettinen, Stefan J. Thieme-Marti, Jeff Everett, Andres Graf, Joakim Pyyry, Juha Kauppinen
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Patent number: 10695587Abstract: A particle therapy system has an irradiation system attached to a rotary drum of a gantry. A radiation treatment cage disposed in the rotary drum includes a movable floor including a horizontal floor portion. The movable floor includes a number of footboards connected bendably and X-ray transmission plates. The movable floor has a slide member at each end thereof, and the slide member is movably attached to a guide rail that is provided for each of opposite side surfaces of the irradiation system. X-ray sources are disposed outside the rotary drum apart from each other in a circumferential direction of the rotary drum and attached to the outer surface of the rotary drum. The irradiation system includes X-ray detection systems opposite to the X-ray sources.Type: GrantFiled: August 21, 2018Date of Patent: June 30, 2020Assignee: Hitachi, Ltd.Inventors: Tsutomu Yamashita, Tatsuya Fujisawa, Takenori Nishimura
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Patent number: 10687897Abstract: Methods and systems for providing treatment planning information for a neurology procedure, including neurosurgical procedures. A database containing historical data about historical procedures is accessed. Historical data relevant to a neurology procedure is determined, based on a determination of similarity to a set of data characterizing the neurology procedure. Historical instances of procedure parameters relevant to the neurology procedure are determined and displayed.Type: GrantFiled: September 15, 2014Date of Patent: June 23, 2020Assignee: Synaptive Medical (Barbados) Inc.Inventors: Wesley Bryan Hodges, Norman Pyo, Cameron Anthony Piron, Kelly Noel Dyer
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Patent number: 10688320Abstract: Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enough information to determine the location of a target region due to, for example, poor or low contrast and/or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images.Type: GrantFiled: May 30, 2018Date of Patent: June 23, 2020Assignee: RefleXion Medical, Inc.Inventors: Yevgen Voronenko, Peter Demetri Olcott, Debashish Pal, Rostem Bassalow