Sample Mechanical Transport Means In Or For Automated Analytical System Patents (Class 422/63)
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Patent number: 8790577Abstract: A sample analyzer is disclosed. In one embodiment, the sample analyzer includes an analysis section for analyzing a sample by using a reagent to obtain numerical data and distribution diagram of particles contained in the sample; a display device; an information receiver for receiving an input of reagent information assigned to the reagent; a determination section configured for determining whether or not the reagent satisfies a condition to determine that the reagent is a genuine product based on the reagent information; and a controller that controls the display device to display both the numerical data and the distribution diagram if the reagent satisfies the condition by the determination section and to display the numerical data without displaying the distribution diagram if the reagent does not satisfy the condition by the determination section.Type: GrantFiled: September 12, 2008Date of Patent: July 29, 2014Assignee: Sysmex CorporationInventors: Toru Mizumoto, Ryuichiro Ebi, Keisuke Tsutsumida, Yousuke Tanaka, Junya Inoue
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Publication number: 20140199208Abstract: The invention relates to a device (1) for closing an opening in a container lid, and to the use of said device (1) in a container lid that is provided for covering reagent vessel containers in automatic analysis apparatus. The closure device comprises a fastening element (2), a closure element (20), two levers (14), and a plurality of bearings (18, 16, 24).Type: ApplicationFiled: January 14, 2014Publication date: July 17, 2014Applicant: Siemens Healthcare Diagnostics Products GmbHInventor: Thomas Butz
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Publication number: 20140199772Abstract: Apparatus and processes for automated diagnostic testing may include cuvette dispensing, test sample dispensing, reagent dispensing, incubation, photo-optical measuring, and a control in operative communication with the cuvette dispensing unit, the test sample dispenser, the reagent dispenser, the incubation unit, and the measuring unit. A cuvette removal location, a reagent removal location, a measuring location, and a collection receptacle may be situated along a first common circular arc having first geometric center. A cuvette-moving arm and a reagent-dispensing arm have a common axis of rotation passing through this geometric center. A sampling position, a sample dispensing position, an additional rinsing position, and an additional washing position, may all be provided on a second circular arc having second geometric center that has a second axis of rotation for a rotatable sampling arm of the test sample dispenser.Type: ApplicationFiled: March 14, 2014Publication date: July 17, 2014Applicant: DIAGON Kft.Inventors: Levente Kiss, Kornel Nagy, Matyas Petoe, Laszlo Izsak, Jozsef Antal
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Publication number: 20140199779Abstract: An automatic analyzer is capable of controlling the gap between the tip of the sample nozzle and the bottom surface of the reaction container and restricting the sample attached to the tip of the sample nozzle. A movement distance of an arm is calculated and stored while the tip of the sample nozzle contacts a coordinate measurement stand until a stop position detector detects a stop position detection plate. The sample nozzle is moved toward the bottom surface of the reaction container and is stopped at the time when the stop position detector detects the stop position detection plate. The arm is moved upwardly for the movement distance stored in memory from this position. The sample nozzle can be stopped such that the tip of the sample nozzle is contacted to the bottom surface of the reaction container and the bend (warp) of the sample nozzle is restricted.Type: ApplicationFiled: May 17, 2012Publication date: July 17, 2014Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Akihiro Yasui, Kazuhiro Nakamura, Hitoshi Tokieda
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Patent number: 8778266Abstract: A slide processing apparatus is disclosed. The apparatus comprise a liquid transporter for transporting a staining liquid reserved in a first liquid container and a washing liquid reserved in a second liquid container; a first instruction receiver for receiving a first instruction that instructs to initiate preparation of a slide stained with the staining liquid; a second instruction receiver for receiving a second instruction that instructs to initiate washing of a housing element which accommodates therein a slide to be stained; and a controller. When receiving the first instruction, the controller performs staining of the slide accommodated in the housing element by causing the liquid transporter to transport the staining liquid into the housing element. When receiving the second instruction, the controller performs washing of the housing element by causing the liquid transport to transport the washing liquid into the housing element.Type: GrantFiled: January 31, 2012Date of Patent: July 15, 2014Assignee: Sysmex CorporationInventor: Mitsuo Yamasaki
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Patent number: 8772036Abstract: A method is described for distributing samples within an automated analyzer from a linear arrangement of sample vessels to a processing plate in a two-dimensional n×m arrangement wherein samples are sorted, followed by transfer with a pipetting device with a linear arrangement to a processing vessel in a two-dimensional n×m arrangement and subsequent processing of samples using a second pipetting device which has a two-dimensional n×m arrangement.Type: GrantFiled: June 27, 2011Date of Patent: July 8, 2014Assignee: Roche Molecular Systems, Inc.Inventors: Paul Frank, Andreas Gisler, Robert Huesler, Rolf Knobel, Siegfried Mueller, Urs Schnieper, Heinz Trueeb
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Patent number: 8772037Abstract: In an analysis system having an analysis apparatus using a reagent container having a memory to store reagent information concerning the reagent in the reagent container and a remote computer, the following steps are executed: reading out the reagent information from the memory of the reagent container; judging, based on the read reagent information, whether or not the reagent in the reagent container is usable; when it is judged that the reagent in the reagent container is unusable, writing data representing the reagent is unusable into the memory of the reagent container; and when it is judged that the reagent in the reagent container is unusable, registering the data representing the reagent is unusable, into a reagent database managed by the remote computer in association with identification information to identify the reagent container. Thus, it is possible to automatically identify the reagent, which should not be used, and to manage the reagent not so as to use it for the analysis.Type: GrantFiled: July 22, 2005Date of Patent: July 8, 2014Assignee: Wako Pure Chemical Industries, Ltd.Inventors: Masahiro Satomura, Hishiri Komiyama
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Methods and systems for efficient automatic slide staining in immunohistochemistry sample processing
Patent number: 8765476Abstract: Automated sample processing systems may include onboard efficient high-speed mixing of at least two components with an automatic vertical force fluidic turbulent component mixer of which a mixed component may be aspirated and high-speed dispensed in a mixing vial. Other aspects may include single sweep applying a multi-treatment cleaning cycle to at least one slide. A multi-treatment cleaning cycle may include a washing treatment and a drying treatment. In yet other aspects the present invention may include an automated recovery sample processing system with the capability of detecting at least one immediate condition of a fortuitously terminated automatic sample processing run and perhaps even an automatic terminated sample processing run reconstruction calculator.Type: GrantFiled: December 22, 2009Date of Patent: July 1, 2014Assignee: Biocare Medical, LLCInventors: Saradha Avantsa, Ravishankar Melkote, Thomas Maxwell, Geoffrey Cook -
Patent number: 8765475Abstract: Various embodiments disclose a colorimetric absorbance measurement method and a system for performing the same. The method comprises driving a reaction tray carrying a plurality of reaction cuvettes to rotate at a speed; transferring or rotating filters on a filter wheel to a light path of a light beam, starting from a filter of a first wavelength; and sampling photoelectric data when the light beam has passed through each reaction cuvette in some embodiments. The method ensures consistency in the measurement and synchronization between the calibration and the sample test and reliability of the measurements. Various embodiments simplify data processing and reduce the complexity of the system.Type: GrantFiled: October 23, 2008Date of Patent: July 1, 2014Assignee: Shenzhen Mindray Bio-Medical Eletronics Co., Ltd.Inventors: Lihua Zhou, Zhihong Wang, Yanwen Weng, Feng Li
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Publication number: 20140178979Abstract: An apparatus comprises: a first chromatographic column fluidically coupled to a source of sample and a source of a first chromatographic mobile phase solvent; a second chromatographic column fluidically coupled to the first column; a source of a second mobile phase solvent fluidically coupled between the first and second columns; and a detector, the first chromatographic column being configurable to receive, in a trapping step, the first solvent and sample and to retain a first portion of a plurality of analytes therein and to pass a second portion of the plurality of analytes therethrough, the second chromatographic column being configurable, in the trapping step, to receive the second portion of the plurality of analytes and the first and second solvents and to retain the second portion of the plurality of analytes therein, the detector being arranged to receive the second and first portions in respective first and second elution steps.Type: ApplicationFiled: December 21, 2012Publication date: June 26, 2014Inventors: Joseph HERMAN, Sarah J. FAIR, Dayana ARGOTI
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Patent number: 8757864Abstract: A chemical analyzer supplies a sample and a reagent into a reaction container provided with an opening mixes a fluid which is to be measured and contains the sample and reagent supplied into the reaction container, measures a property of the fluid in the reaction container, and controls the drive for the mixer. The mixer has a vertical drive machine to move the mixing tool up and down. The control unit controls the vertical drive machine to move the mixing tool up and down in the fluid to be measured in the reaction container so as to cause upward and downward flow of the fluid which is to be measured and is positioned below the mixing tool.Type: GrantFiled: May 8, 2007Date of Patent: June 24, 2014Assignee: Hitachi High-Technologies CorporationInventors: Hironobu Yamakawa, Hideo Enoki, Isao Yamazaki, Nobuhiro Tsukada
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Patent number: 8759080Abstract: A biological growth plate scanner includes a multi-color illumination system that illuminates a biological growth plate with different illumination colors. A monochromatic image capture device captures images of the biological growth plate during illumination of the growth plate with each of the illumination colors. A processor combines the images to form a composite multi-color image, and/or individual components of the composite image, and analyzes the composite image to produce an analytical result such as a colony count or a presence/absence result. The biological growth plate scanner may include both front and back illumination components. The back illumination component may include a diffuser element disposed under the biological growth plate. The diffuser element receives light from one or more laterally disposed illumination sources, and distributes the light to illuminate a back side of the biological growth plate.Type: GrantFiled: February 2, 2009Date of Patent: June 24, 2014Assignee: 3M Innovative Properties CompanyInventors: Josef A. Graessle, Stephen B. Schenk, Michael C. Lea
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Patent number: 8758702Abstract: A clinical diagnostic sample analyzer for analyzing a sample of a patient is disclosed. The analyzer includes a telescoping closed-tube sampling assembly with a sample probe concentrically housed within a piercing probe and a venting mechanism. The closed-tube sampling assembly is used for aspirating a sample from a sample tube for analysis by a clinical diagnostic sample analyzer.Type: GrantFiled: May 4, 2006Date of Patent: June 24, 2014Assignee: Instrumentation Laboratory CompanyInventors: Matthew Blouin, Gregory Murphy, Diana Mackenzie, Alan Weeks, Daniel Kobrenski
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Patent number: 8758707Abstract: An apparatus and method for applying reagents to tissue mounted on slides, in the field of histology is disclosed. The apparatus holds a number of slides, in slide trays, which are loaded onto the apparatus. Each slide tray forms a batch of slides, with all the batched forming a group. The apparatus holds a number of reagents, grouped into a first group comprising bulk type reagents, and a second group comprising antibodies or probes, and detection systems, for identifying elements of the tissue. A group fluid dispenser, in the form of a robot arm, dispense reagents to the group of slides. Each batch of slides has its own batch fluid dispenser to dispense reagents onto the batch of slides. In on embodiment, the group fluid dispenser dispense antibodies, probes, detection reagents to all slides depending on the protocol defined for each slide, and the batch dispensers dispense bulk reagent to each batch, thus freeing the group fluid dispense from dispensing bulk reagents to all slides.Type: GrantFiled: June 16, 2009Date of Patent: June 24, 2014Assignee: Leica Biosystems Melbourne Pty LtdInventors: Andrew Watkins, Nathan Ray, David Huang
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Patent number: 8758683Abstract: A system and method for processing, i.e., sampling and tracking, plant material requires the ability to identify each plant in a plurality of plants. Initially, samples are taken from selected plants and are collected in respective storage locations in a magazine. During sampling, the identity of the plant source for each plant sample is stored. Further, the identity of each storage location receiving a plant sample is stored. Subsequently, the samples are transferred from the storage locations and are placed in respective wells of a receiving member for further downstream processing. Again, the identity of each well receiving a plant sample is stored. As a result, a plant sample in a well can be traced back to its plant source.Type: GrantFiled: August 8, 2007Date of Patent: June 24, 2014Assignee: Syngenta Participations AGInventors: William Michael Lafferty, Scott Wayne Beaver, Charles Wilson Tweedy, Elizabeth Ann George, Walter James Frandsen, Jr.
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Patent number: 8758684Abstract: An automatic analysis system, which is capable of quickly performing reinspection, includes a sample rack which holds a sample vessel containing a sample; a sample rack input unit in which the sample rack is input; a carrier line which carries the sample rack; a plurality of automatic analyzers arranged along the carrier line; a sample rack holding unit which holds the sample rack storing an analyzed sample; a sample rack collection unit which collects the sample rack storing an analyzed sample; a carrier line for reinspection which returns the sample rack containing a sample subjected to reinspection depending on analysis results; and a controller for returning the sample rack from the sample rack holding unit through the carrier line for reinspection and controlling any one of automatic analyzers different from one that has previously performed analysis to perform reanalysis of the sample.Type: GrantFiled: August 3, 2007Date of Patent: June 24, 2014Assignee: Hitachi High-Technologies CorporationInventors: Kenichi Yagi, Takayuki Noda, Kenichi Takahashi, Kenji Teshigawara, Atsushi Suzuki
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Patent number: 8758685Abstract: An automatic analyzer is free from limitations on layout of various mechanisms, and thus causing no bottlenecks, for example, in a space-saving design of the automatic analyzer. This invention includes a coaxial planar duplex arrangement of two dilution disks each with annularly disposed dilution cells, and the dilution disks A and B operate independently of each other. Various mechanisms (parent-sample sampling mechanism, diluent delivery mechanism, diluent/sample mixing mechanism, and diluted-sample sampling mechanism) used in a dilution process can each access the two dilution disks. The dilution process for a parent sample, executed on the dilution disks A and B, can be continuously conducted by providing a fixed delay in operational timing between the two dilution disks.Type: GrantFiled: September 9, 2008Date of Patent: June 24, 2014Assignee: Hitachi High-Technologies CorporationInventors: Hidenobu Komatsu, Tetsuya Fujisawa
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Patent number: 8753572Abstract: Stepped portions of a flow channel are reduced by completely fixing the channel that extends to the measuring unit, and reducing connections in the channel, thereby to suppress a disturbance in the flow of the liquid suctioned into the measuring unit. A means is provided so that the reaction solution and reagent suctioned will move towards the channel through which the liquids are suctioned.Type: GrantFiled: January 18, 2010Date of Patent: June 17, 2014Assignee: Hitachi High-Technologies CorporationInventors: Susumu Sakairi, Taku Sakazume, Katsuaki Takahashi
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Patent number: 8747746Abstract: An apparatus including at least one of a stainer module and a coverslipper module; an imaging module; a storage module; an automated transport module for transporting at least one slide between at least one of the stainer module and the coverslipper module, the imaging module and the storage module; and a controller. A method including processing at least one slide; determining whether an imaging module is available for imaging of a biological specimen on the at least one slide; transporting the at least one slide to the imaging module using an automated transport module; and transporting the at least one slide to a storage module using the automated transport module when it is determined that the imaging module is not available. A system including a processing module for processing at least one slide including a biological specimen thereon. A machine readable medium.Type: GrantFiled: February 15, 2013Date of Patent: June 10, 2014Assignee: Sakura Finetek U.S.A., Inc.Inventor: Gilles Lefebvre
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Patent number: 8748191Abstract: Analytical systems and methods are provided for simultaneously dispensing metered volumes of fluids at different rates and mixing the fluids to generate a mixed sample having the fluids in proportion to the different rates at which they were dispensed. In some cases two or more of the fluids are premixed prior to mixing with other fluids. In some cases a use composition and diluent are simultaneously dispensed at different rates and premixed to form a diluted sample. One or more reagents may be mixed with the diluted sample and the sample mixture can be analyzed to determine characteristics of the use composition.Type: GrantFiled: August 2, 2010Date of Patent: June 10, 2014Assignee: Ecolab USA Inc.Inventors: Paul R. Kraus, William M. Christensen
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Patent number: 8747745Abstract: An apparatus for analyzing that performs a plurality of treatment operations includes a plurality of treatment units arranged in a vertical direction of the apparatus. The apparatus for analyzing also includes a conveying mechanism configured to convey a sample between the treatment units. The sample is delivered above or in the treatment units. A pipette chip is also delivered above or in the treatment units.Type: GrantFiled: April 8, 2008Date of Patent: June 10, 2014Assignee: Canon Kabushiki KaishaInventor: Atsushi Kitaoka
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Patent number: 8741235Abstract: A two-step method for loading a fluid sample into a disposable fluid analysis cartridge is described. First, capillary action may be used to initially draw a sample through a sample introduction port and into a sample collection reservoir provided in the fluid analysis cartridge. Once the fluid sample has been drawn into the sample collection reservoir by capillary action, a negative pressure may be applied to the cartridge to pull the sample from the sample collection reservoir and into a sample loading channel. A valve may be disposed between the sample collection reservoir and the sample loading channel to prevent backflow of sample into the sample collection reservoir and to retain sample in the sample loading channel.Type: GrantFiled: December 27, 2011Date of Patent: June 3, 2014Assignee: Honeywell International Inc.Inventors: Robert Janisch, Pam Wong, Eric Peltola, Ron Bardell, Mark Kelley
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Patent number: 8741219Abstract: A sample processing system comprising: a transporting apparatus for transporting a sample; a plurality of sample processing apparatuses, arranged along a direction in which the sample is transported by the transporting apparatus, for processing the sample transported by the transporting apparatus; a base on which at least one of the sample processing apparatuses is placed; and a movement restricting section for restricting, on the base, a movement area within which the sample processing apparatus moves, wherein the movement restricting section allows the sample processing apparatus to move on the base so as to change orientation of the sample processing apparatus, is disclosed. A base for a sample processing system and a sample processing apparatus are also disclosed.Type: GrantFiled: December 15, 2009Date of Patent: June 3, 2014Assignee: Sysmex CorporationInventors: Yuichi Hamada, Keisuke Kuwano
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Patent number: 8741655Abstract: A transport system is provided for a sample testing machine. The transport system includes a carrier holding a set of test sample devices and a drive subsystem for moving the carrier through the sample testing machine. The drive subsystem includes a reciprocating motor-driven block engaging the carrier and moving the carrier back and forth in a predetermined longitudinal path extending along a longitudinal axis from an entrance station to a plurality of processing stations in the sample testing machine. The processing stations are accessed as the carrier is moved along the path. The carrier includes features in the form of slots or voids that are detected by strategically placed optical interrupt sensors. As the carrier moves, the slots are detected by the sensors to thereby continuously track the position of the carrier and the test devices as they are moved through the instrument.Type: GrantFiled: March 6, 2008Date of Patent: June 3, 2014Assignee: Biomerieux, IncInventors: Michael James Justin, James Clement Bishop, Stanley Michael Philipak, Mark Joseph Fanning
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Patent number: 8741233Abstract: A disposable blood analysis cartridge for analyzing a blood sample including an optical light scattering measurement channel is described. In use, processed sample may be introduced into a sheath fluid channel at an angle, ?, of approximately 90 degrees, relative to the direction of flow of the sheath fluid. In addition, delivering the sample from the side into the sheath fluid may facilitate better positioning of the core within the hydrodynamic focusing channel for measurement.Type: GrantFiled: December 27, 2011Date of Patent: June 3, 2014Assignee: Honeywell International Inc.Inventors: Ron Bardell, Tzu-Yu Wang, Mark Washa
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Patent number: 8741134Abstract: In a preferred embodiment, a sample container storage part for storing a number of sample containers S, a nozzle for dropping a sample component separated and supplied by an LC and an additive liquid such as digestive fluid supplied from another liquid supplying part to the sample container S, a carrying mechanism for carrying and positioning the sample container at an arbitrary position under the nozzle, and a second nozzle, serving as a suction/injection mechanism, for sucking in the fractionated/collected sample component and injecting the sample component to another LC. The carrying mechanism provides a rotation mechanism. The carrying mechanism rotates over 180 degrees and carries the sample container S completed with fractionating/collecting to the position of the second nozzle, and the sample is sucked in by the second nozzle and injected to the LC of next stage.Type: GrantFiled: December 20, 2005Date of Patent: June 3, 2014Assignee: Shimadzu CorporationInventors: Shuzo Maruyama, Yosuke Iwata
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Patent number: 8741234Abstract: A disposable blood analysis cartridge for analyzing a blood sample including an optical absorbance measurement channel is described. The optical absorbance measurement channel includes a plasma separation region and at least one sub channel including a cuvette that is in fluid communication with the plasma separation region and configured to receive a plasma portion of a blood sample that has been passed through the plasma separation region. A negative pressure may be applied to the cartridge to draw the sample through the plasma separation region and into the sub channel including the cuvette.Type: GrantFiled: December 27, 2011Date of Patent: June 3, 2014Assignee: Honeywell International Inc.Inventors: Tzu-Yu Wang, Ron Bardell, Lynn Seifried
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Publication number: 20140147335Abstract: An automatic analyzer enables users to perform working steps easily and reliably by switching a display screen irrespective of a skill level of the user. The automatic analyzer, which determines a consistency of a test item, includes a display/input section to display a plurality of working steps relating to necessary work flow for measurement. The display/input section is adapted to selectively present a maximized workflow display and a reduced workflow display. The maximized workflow display shows a series of operations and works, and further shows a plurality of operations and works in an order that the plurality of operations and works are processed. In a reduced display of the work flow, the reduced workflow display shows details of a specific operation or work, and a position of the specific operation or work in a sequence that the entire series of operations and works are processed.Type: ApplicationFiled: May 22, 2012Publication date: May 29, 2014Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Sayaka Sarwar, Tatsuya Tokunaga, Miki Taki, Toshihide Orihashi, Hiroki Mori, Yoichi Aruga, Takashi Nakasawa
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Patent number: 8734720Abstract: Automated testing system arrangements using a docking station. One system includes a unit including: a) a polygonal base having a plurality of sides, a number of the plurality of sides including a docking station for mating with a mobile equipment carrying cart; and b) a robotic arm having a stationary base positioned on or in the polygonal base and configured to interact with the equipment on each mobile equipment carrying cart.Type: GrantFiled: March 27, 2009Date of Patent: May 27, 2014Inventors: Michael J. Nichols, Louis J. Guarracina
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Patent number: 8734719Abstract: A parts supply device for supplying disposable part selected from a cuvette and pipette tip, comprising: a storage section for storing a plurality of disposable parts; a sort section for sorting the disposable parts supplied from the storage section, the sort section including a push-up plate to be capable of pushing up the disposable part in the supplied parts and a wall section arranged at the downstream side of the push-up plate so as to be adjacent to the push-up plate, wherein the push-up plate is configured to vertically move along the wall section between a first position and a second position that is above the first position; and a transfer section for transferring one by one the disposable part supplied by the push-up plate over the wall section.Type: GrantFiled: March 9, 2007Date of Patent: May 27, 2014Assignee: Sysmex CorporationInventors: Kazunori Mototsu, Masayuki Nakagawa
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Patent number: 8734721Abstract: An analyzer includes, as a cleaning system, a cleanser tank that contains a cleanser; a cleaning-water tank that contains cleaning water; a connection pipe that connects the cleanser tank with the cleaning-water tank; a pump that is provided to the connection pipe and pumps the cleanser out of the cleanser tank to the cleaning-water tank; a valve that is provided to the connection pipe and adjusts a flow of the cleanser from the cleanser tank into the cleaning-water tank; and a control unit that opens the valve and causes the pump to pump the cleanser out of the cleanser tank to the cleaning-water tank via the connection pipe to clean the inside of the cleaning-water tank and the insides of cleaning-water flow-path constituents that form a flow path through which the cleaning water flows from the cleaning-water tank when the specimen is subjected to an analysis process.Type: GrantFiled: March 24, 2010Date of Patent: May 27, 2014Assignee: Beckman Coulter, Inc.Inventor: Shinya Matsuyama
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Patent number: 8734735Abstract: An automated machine for handling and embedding tissue samples contained on microtome sectionable supports. The machine includes an input member configured to hold a plurality of the microtome sectionable supports prior to a tissue embedding operation. An output member is configured to hold a plurality of the microtome sectionable supports after the tissue embedding operation. A cooling unit is configured to hold at least one of the microtome sectionable supports during the tissue embedding operation. A motorized carrier assembly is mounted for movement and configured to hold at least one of the microtome sectionable supports. The carrier assembly moves the support from the input member to the cooling unit and, finally, to the output member. A dispensing device dispenses an embedding material onto the microtome sectionable support and at least one tissue sample carried by the microtome sectionable support during the embedding operation.Type: GrantFiled: March 14, 2011Date of Patent: May 27, 2014Assignee: Biopath Automation, L.L.C.Inventors: Warren P. Williamson, IV, Thomas J. Ward, Stephen P. Whitlatch
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Patent number: 8728396Abstract: The present invention is a sample analyzer including: a first and a second measurement unit configured to measure a sample accommodated in a sample container; a rack transport unit configured to transport each of a plurality of sample containers held in a sample rack to either the first or the second measurement unit; and a controller configured to acquire a measurement item information indicating a measurement item of each of samples accommodated in the plurality of sample containers held in the sample rack, determine a sample container to be a transport object and a measurement unit to be a transport destination of the sample container based on the acquired plurality of measurement item information, and control the rack transport unit to transport the sample container determined as the transport object to the measurement unit determined as the transport destination.Type: GrantFiled: March 9, 2011Date of Patent: May 20, 2014Assignee: Sysmex CorporationInventors: Keisuke Kuwano, Daigo Fukuma
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Patent number: 8726944Abstract: A method in a fraction collector for accurate positioning of a dispensing device with respect to wells of a micro plate in which prior to the dispensing a sensing device is moved over the micro plate the sensing device being able to detect the number of walls between the wells in the rows and columns of the micro plate.Type: GrantFiled: April 22, 2009Date of Patent: May 20, 2014Assignee: GE Healthcare Bio-Sciences ABInventors: Johan L. Carlsson, Hakan Frojdh, Pia Liljedahl, Lars Rosengren, Johan Svensson, S. Fredrik Svensson, Bengt Asberg
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Publication number: 20140134748Abstract: The present disclosure provides a biological field effect transistor (BioFET) device testing and processing methods, system and apparatus. A wafer-level bio-sensor processing tool includes a wafer stage, an integrated electro-microfluidic probe card, and a fluid supply and return. The integrated electro-microfluidic probe card includes a fluidic mount that may be transparent, a microfluidic channels in the fluidic mount, at least one microfluidic probe and a number of electronic probe tips at the bottom of the fluidic mount, fluidic and electronic input and output ports on the sides of the fluidic mount, and at least one handle lug on the fluidic mount. The method includes aligning a wafer, mounting the integrated electro-microfluidic probe card, flowing a test fluid, and measuring electrical properties. The tool may also be used for stamping or printing a fluid in the device area on the wafer.Type: ApplicationFiled: November 9, 2012Publication date: May 15, 2014Applicant: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD.Inventors: Yi-Shao LIU, Fei-Lung LAI, Chun-Ren CHENG, Chun-Wen CHENG
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Patent number: 8721964Abstract: An animal blood cell measuring apparatus comprising: a specimen preparation section for preparing a measurement specimen from blood of an animal; a characteristic information obtaining section for obtaining characteristic information indicating a characteristic of the measurement specimen, from the measurement specimen prepared by the specimen preparation section; and a controller configured for performing operations comprising: (a) classifying aggregate reticulocytes contained in the blood from other blood cells, based on the characteristic information obtained by the characteristic information obtaining section; and (b) outputting information regarding a number of the classified aggregate reticulocytes.Type: GrantFiled: March 19, 2010Date of Patent: May 13, 2014Assignee: Sysmex CorporationInventors: Yoichi Nakamura, Hideki Hirayama, Hideaki Matsumoto, Keiko Moriyama
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Patent number: 8721965Abstract: A transporting apparatus for transporting a specimen rack holding a specimen container containing a specimen, comprising: an engage unit capable of engaging with the specimen rack; and a moving mechanism for moving the engage unit in a transport direction of the specimen rack, the transport direction including a first direction and a second direction opposite to the first direction, wherein the engage unit comprises: a pair of engage members, capable of mutually approaching and separating relative to the transport direction, and engaging with the specimen rack gaplessly relative to the transport direction by the approaching operation or the separating operation; and a driver for driving the pair of engage members so as to perform the approaching operation and the separating operation. A specimen analyzing apparatus is also disclosed.Type: GrantFiled: November 16, 2009Date of Patent: May 13, 2014Assignee: Sysmex CorporationInventor: Hiroki Koike
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Patent number: 8715571Abstract: A system and method for receiving and ejecting a test strip of a fluid testing device. The system includes parallel first and second guide rails defining a rail cavity between the guide rails. A sled includes a sled post and opposed first and second side leg sets each having at least one deflectable leg. Each of the deflectable legs is externally slidably engaged to one of the guide rails limiting the sled to only sliding motion in either a loading direction or an opposite ejection direction. An actuator arm is rotatably connected to a mechanism assembly. The sled post is received in an actuator arm slot. Actuator arm rotation in a loading rotational direction displaces the sled in the loading direction in a sliding motion. Subsequent opposite rotation of the actuator arm in an ejection rotational direction displaces the sled in the ejection direction and ejects the test strip.Type: GrantFiled: June 29, 2012Date of Patent: May 6, 2014Assignee: Roche Diagnostics Operations, Inc.Inventors: James R. Hanson, Derek C. Lotarski, Matthew C. Sauers, Anthony J. Uberta, III
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Patent number: 8709814Abstract: In a computer-controlled, automated method, a nucleic acid amplification procedure is performed within a prescribed incubation temperature range within an instrument that comprises at least one thermal element situated at a first location of the instrument and an amplification incubator situated at a second, spaced-apart location of the instrument. A receptacle and its contents are exposed to the thermal element for a predetermined period of time at the first location, such that the temperature of the contents of the receptacle is adjusted to approximate the incubation temperature. The receptacle is then moved from the first location and into the amplification incubator, and, in the amplification incubator, a nucleic acid contained in the contents of the receptacle is subjected to the nucleic acid amplification procedure.Type: GrantFiled: April 16, 2012Date of Patent: April 29, 2014Assignee: Gen-Probe IncorporatedInventors: Kelly G. Ammann, Robert E. Schneider, Robert J. Smith
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Patent number: 8709345Abstract: To reduce measurement time, it may be considered to quicken reaction or speed up analytic determination. In existing analyzing devices, photometry is performed, typically, about every 15 seconds, so that it has not been possible to secure satisfactory reproducibility. Namely, reducing the measurement time and securing reproducibility have not been compatible. It has therefore been desired to increase the number of times of measurements performed in a short period of time. A cell disk is controlled to stop at a position for photometry during the time after a sample and a reagent are mixed and before measurement is finished and, while the cell disk is stopped, photometry is performed once or plural times thereby increasing the total number of times of measurements.Type: GrantFiled: March 1, 2010Date of Patent: April 29, 2014Assignee: Hitachi High-Technologies CorporationInventors: Sakuichiro Adachi, Akihisa Makino
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Publication number: 20140112829Abstract: A tube strip handling and heating frame having a rectangular outer frame having two spaced longitudinal walls extending in a longitudinal direction, and two spaced lateral walls extending in a lateral direction and extending between respective ends of the longitudinal walls. The outer frame forms an enclosure having an open upper side and an open lower side. The frame also has a number of tube strip wells located inside the outer frame, each tube strip well has a slot elongated in the lateral direction, and each slot is configured to receive a respective tube strip through the open upper side and support the respective tube strip in a vertical direction. The tube strip wells are arranged in a series along the longitudinal direction.Type: ApplicationFiled: October 22, 2012Publication date: April 24, 2014Applicant: QIAGEN GAITHERSBURG, INC.Inventors: BRADLEY SCOTT THOMAS, Carl Theodore Edens, Andrew Leonard, Bert Jungheim, Peter Haviernik, Bowen Cui
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Patent number: 8703492Abstract: An automated sample processing system having a sample input adapted to simultaneously receive a number of sample containers, a reagent input adapted to receive one or more new reagent supplies, a consumable input adapted to receive one or more new consumable supplies, a solid waste output adapted to receive used consumable supplies, a liquid waste output adapted to receive one or more used reagent supplies, and a processing center. The processing center includes a decapper adapted to remove a lid from at least one sample container, an aspirator adapted to remove a specimen from the at least one sample container and transfer the specimen to an output vessel, and a capper adapted to replace the lid on the at least one sample container.Type: GrantFiled: October 9, 2009Date of Patent: April 22, 2014Assignee: Qiagen Gaithersburg, Inc.Inventors: Brian Austin Self, Jonathan Matthew Miller, Carl Theodore Edens
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Patent number: 8703056Abstract: An automated analyzer and a reagent vessel opening/closing device allows reduction of the time period during which reagent vessels are opened unnecessarily. The reagent vessel opening/closing device opens or closes the lids of reagent vessels when the reagent vessels are at a dispensing/stirring position on a reagent vessel transfer device of an automated analyzer. The device for opening/closing the lids of reagent vessels includes a hook base secured to a unit base and a hook-base drive unit for moving the hook base with respect to the unit base in opening/closing directions of the lids of the reagent vessels. A plurality of hooks are attached to the hook base and a plurality of motors are each adapted to slide one of the hooks with respect to the hook base to engage/disengage the hook with/from the lid of a reagent vessel.Type: GrantFiled: December 9, 2010Date of Patent: April 22, 2014Assignees: Hitachi High-Technologies Corporation, F. Hoffman-La Roche AGInventors: Susumu Sakairi, Katsuaki Takahashi, Stephan Sattler, Reinhold Kraemer
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Patent number: 8703491Abstract: Disclosed herein is a sample supply device that alternates between the supply of samples from one sample line while cleaning a second sample line and then supplying a second sample from the second sample line while cleaning the first sample line. This is repeated in rapid succession to allow greater speed in analyzing a plurality of samples in a shorter amount of time.Type: GrantFiled: November 16, 2012Date of Patent: April 22, 2014Assignee: Vivia Biotech S.L.Inventor: Alex Okun
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Patent number: 8703054Abstract: The present invention relates to analytical apparatus comprising: a passage (45) in which an analytical tool (2) is moved from above to below; and a movement block (51), made capable of reciprocatory movement in the horizontal directions (D1, D2), for moving the analytical tool (2) incoming through the passage (45) in the direction (D1). This analytical apparatus is constructed such that, by erecting the analytical tool (2) on the movement block (51) positioned directly below the outlet (45B) of the passage (45) and causing the movement block (51) to move in the D1 or D2 direction, the analytical tool (2) is tipped over, and the analytical tool (2) is placed in a horizontal condition on the movement block (51).Type: GrantFiled: June 1, 2005Date of Patent: April 22, 2014Assignee: ARKRAY, Inc.Inventor: Hidenari Yamagata
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Patent number: 8701730Abstract: Problems of a conventional cover glass sticking device, in which a slide glass having one end side, where a describing portion is formed, is stored in a storage container and the one end side is always projected from level of a protection liquid therein, are solved by the device of the present invention.Type: GrantFiled: April 21, 2009Date of Patent: April 22, 2014Assignees: Sakura Seiki Co., Ltd., Sakura Finetek Japan Co., Ltd.Inventors: Kohji Naritake, Kiyokazu Iijima, Seiichi Takizawa, Tetsu Nagabayashi
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Patent number: 8697448Abstract: The present invention discloses a user personalized operating method and operating apparatus for use in a chemistry analyzer, the method comprises following steps: initiating the operating software of the chemistry analyzer; loading a profile, the profile comprising at least a database containing combinations of controls for respective users; retrieving configuration information of the function components from the database; and setting display interface and function components by the chemistry analyzer according to the configuration information. The present invention realizes different combinations of controls and display interface by use of the profile and thus operating software of different versions can be provided.Type: GrantFiled: October 19, 2007Date of Patent: April 15, 2014Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.Inventors: Yandong Yin, Yun He, Weizhong Di
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Patent number: 8696990Abstract: A device for the photometric examination of samples has a sample-holder apparatus for at least two sample vessels, and a measuring apparatus and a moveable apparatus. The sample-holder apparatus is designed to be stationary, and the measuring apparatus is arranged on the moveable apparatus such that it can be displaced by means of the moveable apparatus.Type: GrantFiled: September 7, 2010Date of Patent: April 15, 2014Assignee: Siemens Healthcare Diagnostics Products GmbHInventors: Paul Meller, Holger Pufahl
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Patent number: 8691149Abstract: A component of a laboratory automation system that integrates (a) separating a solid magnetic substrate from the liquid contents of a reaction vessel, (b) management of the thermal characteristics of the component of the laboratory automation system, (c) automated loading of multi-well plates and tip combs into the component of the laboratory automation system, (d) automated unloading of multi-well plates and tip combs from the component of the laboratory automation system, and (e) reading of radio frequency identification tags attached to multi-well plates.Type: GrantFiled: October 24, 2008Date of Patent: April 8, 2014Assignee: Abbott LaboratoriesInventors: Patrick P. Fritchie, Gregory E. Gardner, Richard W. Mahoney
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Patent number: 8691147Abstract: The invention provides an apparatus and a method of processing a biological and/or chemical sample in a liquid droplet. The apparatus comprises a processing compartment, which is defined by a reservoir and an immobilization member. The processing compartment is further adapted to accommodate a medium, which is immiscible with the liquid droplet, and of a lower surface energy than the liquid of the liquid droplet. The reservoir is defined by a circumferential wall and a base. The immobilization member is arranged within the reservoir and comprises a surface that is patterned in such a way that it comprises at least one predefined immobilization area. The predefined immobilization area within the patterned surface is of a higher surface energy than the medium. The liquid droplet is disposed onto the predefined immobilization area, whereby the liquid droplet is immobilized thereon via hydrophilic-hydrophilic or hydrophobic-hydrophobic interactions.Type: GrantFiled: November 14, 2007Date of Patent: April 8, 2014Assignee: Agency for Science, Technology and ResearchInventors: Kwong Joo Leck, Nam Yong Kim, Jackie Y. Ying, Li Li, Yong Yeow Lee