Abstract: The invention relates to treatment of a plant with one or more microorganisms for inhibiting a plant pathogen. More particularly, the invention relates to isolated Bacillus strains, and strains having all of the identifying characteristics of these strains, and combinations thereof, for a use comprising the above-mentioned use.

Abstract: The present disclosure relates to an external-use skin preparation composition containing an extract of a fermented product of Red yeast rice. More particularly, it relates to an external-use skin preparation composition capable of providing excellent antioxidant and anti-aging effects by containing, as an active ingredient, an extract of a fermented product of Red yeast rice, which is obtained by further fermenting Red yeast rice, red rice fermented with Monascus purpureus, with yeast.

Abstract: The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.

Abstract: The present invention provides cystobactamides of formula (I): R1—Ar1-L1-Ar2-L2-Ar3-L3-Ar4-L4-Ar5—R2 and the use thereof for the treatment or prophylaxis of bacterial infections.

Abstract: The present invention relates to the fields of malaria and dengue virus. More specifically, the present invention provides compositions and methods useful for the treatment and prevention of malaria and dengue virus. In particular embodiments, a composition comprises mosquito nectar feed and Chromobacterium sp_Panamam (Csp_P).

Abstract: A buffered body fluid expander solution, in which the buffer is a physiologically acceptable buffer that is not an inorganic phosphate buffer, comprises calcium ions and magnesium ions at a concentration ratio of 5:1 to 1:1. The solutions are useful for the manufacture of medicaments and blood volume expanders, for treating hypovolemia or for treating the loss of extracellular and interstitial fluid in subjects suffering with burns, for treating respiratory and/or metabolic acidosis in a subject, for perfusion of the abdominal cavity during peritoneal dialysis of a subject with acute renal failure or an acute toxicity condition, for preventing and/or ameliorating reperfusion injury, and for delivering a therapeutic, test and/or synergistic agent to a subject, including a biological agent, such as at least one stem cell, peptide or genomic derived protein.

Abstract: An anti-tumor traditional Chinese medicine, a preparation method therefor, and uses thereof. This traditional Chinese medicine is prepared by leavening of Pleurotus sp. and Dioscorea bulbifera, pangolin scales, rhubarb, oyster, stiff silkworm, kelp, selfheal, Ligusticum wallichii, barbat skullcap, honeysuckle flower, Oldenlandia diffusa, Radix trichosanthis, Rhizoma anemarrhenae Scutellaria baicalensis, Angelica sinensis, Psoralea corylifolia, Lucid ganoderma, and coix seed.

Abstract: The invention is related to compositions including saponins and saponin-protective agents and related methods. In an embodiment, a composition is included herein. The composition can specifically include a saponin composition comprising saponins and a saponin-protective agent, wherein the saponin-protective agent prevents deglycosylation of the saponins in an aqueous environment containing glycosidase enzymes. Other embodiments are included herein.

Abstract: The present application relates to an anti-microbial system for use in the treatment of microbial infections or control of microbial contamination, which avoids the use of antibiotics. Such infections include mastitis, tuberculosis, cystic fibrosis and the contamination that may result from biofilm formation on medical devices.

Abstract: The present invention provides cystobactamides of formula (I) and the use thereof for the treatment or prophylaxis of bacterial infections.

Abstract: The present invention relates to compositions comprising at least about 8% ?-glucans and/or at least about 8% ?-fucans, which has a prebiotic effect and act as a replacement for in-feed antibiotics. The present invention also relates to extraction methods to obtain such extracts and various uses for the compositions comprising ?-glucans and/or ?-fucans.

Abstract: Disclosed is a Japanese camellia extract, obtained by extracting Camellia japonica flowers by way of a fatty substance or fatty substance mixture, and to a cosmetic composition including one such extract that has, in particular, a skin-moisturizing effect.

Abstract: A method for producing a seed of a plant resistant to seedling diseases is provided which includes contacting a non-pathogenic microbe corresponding to a seed-borne pathogen with a flower part of a host plant around the flowering time and collecting a seed of the host plant colonized by the non-pathogenic microbe obtained thereafter, and a method for controlling seedling diseases using the seed.

Abstract: A method of treating or preventing bacterial infection in an animal comprises administering an effective amount of degraded date pits. Degraded date pits can be produced by the treatment of date pits with fungi.

Abstract: The present invention relates to the Bacillus sp. strains AT-332 (NITE BP-1095) and AT-79 (NITE BP-1094) isolated from nature; and a plant disease control agent, a nematode control agent and a plant growth promoter containing the strains as active bacteria. The Bacillus sp. strains AT-332 and AT-79 strain are effective in controlling both a wide range of various plant diseases and nematode-damage and capable of promoting the growth of useful plants, due to a culture containing a secondary metabolite of the strains or cultivated and isolated live bacteria of the strains being introduced to a plant body or to the culture soil.

Abstract: Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.

Abstract: The present invention is directed to non-aqueous, non-oil liquid compositions comprising Bacillus amyloliquefaciens and a liquid carrier. The present invention is further directed methods of controlling nematodes comprising applying an effective amount of a non-aqueous, non-oil liquid composition comprising Bacillus amyloliquefaciens and a liquid carrier to an area in need of nematode control.

Abstract: The present invention relates to the cosmetic use of a lysate of a bacterium or bacteria belonging to the Vitreoscilla sp. genus (in particular the species: Vitreoscilla filiformis) in a complete fermentation medium, as an active agent for preventing and/or treating dandruff conditions of the scalp, including dandruff conditions of the scalp associated with a prevalence of pathogenic microorganisms on the scalp and/or an imbalance of the scalp ecoflora.

Abstract: A method for increasing the vigor and/or crop yield of agricultural plants under essentially non-existent pathogen pressure, wherein the plants, the plant propagules, the seed of the plants and/or the locus where the plants are growing or are intended to grow are treated with an effective amount of a composition comprising a) the Bacillus subtilis strain with NRRL Accession No. B-21661 or a cell-free extract thereof, and/or a mutant of this strain or extract having all the identifying characteristics of the respective strain or extract as component (I), and b) optionally at least one chemical compound as component (II), selected from the active compound groups A) to J): A) strobilurins; B) carboxamides; C) azoles; D) heterocyclic compounds; E) carbamates; F) other active substances; G) growth regulators; H) herbicides; J) insecticides.

Abstract: Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of compounds.

Abstract: The present invention relates to methods and compositions for treating pulmonary infection. In particular, the present invention provides nanoemulsion compositions and methods of using the same to treat bacteria associated with biofilms (e.g., found in pulmonary infections). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine), industrial, and research applications.

Abstract: Methods of shortening the duration of anti-infective therapy and increasing the effectiveness of anti-infective drugs in subjects with infection are present. The methods are based on altering the replication rate of a pathogen, which makes the pathogen more susceptible to the actions of the anti-infective drug.

Abstract: The present invention relates to a method for increasing the vigor and/or crop yield of agricultural plants under essentially non-existent pathogen pressure, wherein the plants, the plant propagules, the seed of the plants and/or a locus where the plants are growing or are intended to grow are treated with an effective amount of a composition comprising a Bacillus subtilis strain with NRRL Accession No. B-21661, a mutant of the strain having all the identifying characteristics of the strain, or a cell-free extract thereof; and a compound selected from the group consisting of fosetyl, fosetyl-aluminum, propamocarb, and propamocarb hydrochloride; wherein the vigor and/or crop yield of agricultural plants under essentially non-existent pathogen pressure is increased.

Abstract: Embodiments of the invention provide for treating arsenic contaminants in an in situ environment. In accordance with an embodiment of the invention, a stabilized oxidizing agent can be prepared, for instance a stabilized liquid hydrogen peroxide agent, as can an aqueous chelated iron solution. Both the stabilized oxidizing agent and the aqueous chelated iron solution can be alternately introduced into the in situ environment contaminated with arsenic by way of alternate injection screens into the in situ environment so as to remediate the arsenic contamination of the in situ environment.

Abstract: The invention relates to a kit-in-part comprising of a composition for the use as a cleaning and treating of ears of a companion animal and suitable packaging material, wherein the kit-in part additionally consists of components selected from the group of a pharmaceutical composition for use in the treatment of otitis externa, application and dosage information, cannules, cotton swabs, gauzes and information about the cleaning and maintenance ears of a companion animal.

Abstract: The invention relates to compositions comprising abscisic acid, and/or salts, derivatives and analogs thereof, and methods of using the same for improving the health and survival of animal offspring.

Abstract: Dry powder vancomycin compositions and methods for administering and preparing such compositions are provided.

Abstract: The present invention relates to the field of virology. More specifically, the present invention provides methods and compositions useful for treating human cytomegalovirus using Wnt pathway modulators. In a specific embodiment, a method for treating human cytomegalovirus (HCMV) in a patient in need thereof comprises administering an effective amount of Wnt pathway modulator.

Abstract: The present invention relates to a method for enhancing the health of a human comprising administering to the human an effective amount of a composition comprising Bacillus subtilis QST713 or a mutant thereof.

Abstract: Compositions for use in treatment of a variety of tissue diseases include stem cells and stem cell released molecules (SRM's) suspended in an aqueous solution with a cellulosic material or other thickening agent. The stem cells and SRM's can be derived from one or more distinct cell lines. The SRM's can further include one or more mucins, cytokines, or growth factors. Exemplary formulations include stem cells and SRMs derived from epithelial stem cells, corneal limbal stem cells, and fibroblasts. Other compositions and methods for formulation thereof are described.

Abstract: This invention provides a product safe for treating, improving or preventing an inflammatory bowel disease such as ulcerative colitis, and provides a product comprising an insoluble dietary fiber obtained by enzymatic treatment of seeds of a grain plant(s) or germinated young seeds thereof, as well as a food or drink or medicament comprising the product.

Abstract: The invention provides topical compositions and methods for using the compositions. The compositions can be used for the treatment of fibrotic or connective tissue disorders involving scarring, sub-dermal plaque accumulations, or fibrosis of muscle tissue. The disorders can be painlessly treated by the topical application of a composition described herein. One or more calcium channel blocker agents can serve as an active ingredient of the compositions, optionally in combination with, for example, one or more of emu oil and superoxide dismutase. The composition can further include pharmaceutically acceptable carriers that can facilitate the non-invasive transdermal delivery of the active(s) to subdermal sites.

Abstract: Novel actinomycete strain composition and its use.

Abstract: The present invention comprises compositions and methods for enhancing biological processes, such as plant growth or bioremediation. For example, the present invention comprises compositions and methods for effectively remediating chemical and organic wastes and reducing the environmental risk from manure, septic, sewage, oil pollution, and other contaminants.

Abstract: The invention relates to application of 4,4?-diphenylmethane-bis(methyl) carbamates (DPMC) extracted and isolated from Cortex Mori and preparation of medicine for diabetic nephropathy. The pharmaceutical composition is made up of DPMC as active ingredient and the normal drug carriers, and the weight percentage of active ingredient is 0.1-99.5%. For the remarkable effect of prevention and cure for diabetic nephropathy and convenience for use, it will be a new facultative drug for patients.

Abstract: Sensitive skin, mucous membranes and scalps are treated by administering to individuals in need of such treatment, thus effective amounts of at least one extract of a non-photosynthetic and non-fruiting filamentous bacterium cultured in a medium which includes at least one non-sulfurous mineral and/or thermal water, e.g., an extract derived from the bacterium Vitreoscilla filiformis, in particular the strain ATCC 15551, cultured in a medium enriched with water from La Roche Posay.

Abstract: Provided are a feed composition, which can be stored for a long time and is easily produced and adjustable in components, and which can increase the body weight and reduce a feed conversion ratio of farm animals to which the feed composition is fed, and a production method for the feed composition. In the feed composition, a liquid feed additive obtained by fermenting a carbohydrate-containing carbohydrate raw material by Aspergillus is substituted for 5 to 50% on a dry matter basis of a feed raw-material.

Abstract: The invention relates to the use of feed material comprising grain and Agaricus Blazei, comprising the Agaricus species in an amount between 10 to 50% by weight on dry matter, and the feed material having a moisture content of less than 10% (relative to dry matter), for administration to chicken for improvement of egg laying, preferably for improving shell quality and/or for extending the egg laying period. The invention further relates to a process for making the feed material, and feed for laying hens comprising the feed material.

Abstract: The present invention relates to a novel monascuspurpurone compound of formula (I): or a pharmaceutically acceptable derivative thereof as described in the specification, the process for preparation of the same, and the composition comprising the same. The uses of a monascuspurpurone compound for promoting adipocyte differentiation, for increasing the activity of PPAR? and/or C/EBP?, for lowering blood glucose, for preventing and/or treating a disease or disorder related to insulin resistance, and for preventing and/or treating metabolic syndrome or its complications are also provided.

Abstract: The invention relates to relatively light and thermally stable granulated, fermentation-broth-based animal feed additives having a high content of L-lysine and to low-loss methods for their production from broths obtained by fermentation.

Abstract: The present invention relates to food for nutritional therapy of AIDS belonging to functional foods. It is made from deep fermentation of Morchella spp and Tricholoma matsutake in traditional Chinese medicine medium extracting from Callicarpa bodinieri. The combination and synergistic effect of the food components could alleviate fear of chill caused by large number of broken erythrocyte in patients with AIDS, improve immunity effectively, ameliorate symptoms and physical signs, promote body activities, further postpone complication occurrence and improve patient's quality of life.

Abstract: Topical compositions comprising grape seed and at least three of folic acid, biotin, Bifidobacterium longum extract and Echinacea purpurea.

Abstract: A method of treating or preventing bacterial infection in an animal comprises administering an effective amount of degraded date pits. Degraded date pits can be produced by the treatment of date pits with fungi.

Abstract: Disclosed is a pharmaceutical natural composition containing both statin compounds (mevinolin and mevinolinic acid) serving as cholesterol biosynthesis inhibitors and coenzyme Q (ubiquinone-10: CoQ10 and ubiquinone-9: CoQ9) compounds which are substances that inhibit factors causing complications such as myalgia involved in long-term use of the statin, prepared using Monascus sp. and natural medicinal substances such as ginseng, mushrooms and cereals.

Abstract: Molecules secreted or derived from probiotic bacteria are provided for use in compositions and methods for the treatment and/or prevention of infection by pathogenic viruses. The isolated secreted molecules can also be used in nutritional or medical food products which provide probiotics to the gastrointestinal tract of a mammal.

Abstract: The present invention relates to skin care compositions, including cosmeceuticals, for topical application, and more particularly, a skin cream, comprising exosomes and cell culture medium conditioned by cells grown in two-dimensional culture. Also included are methods of making and using such compositions and kits comprising the skin cream therein.

Abstract: A composition comprising 4-oxovaleric acid present in an amount of 0.05 to 1% by weight (as supplied) of the composition and leuconostoc/radish root ferment filtrate present at 0.2 to 2% by weight (as supplied) of the composition.

Abstract: A nutritional composition comprising a combination of non-digestible oligosaccharides and a product obtained by incubating an aqueous substrate by bifidobacteria and optionally a product obtained by incubating an aqueous substrate by S. thermophilus. Said combination reduces bacterial translocation and improves the intestinal barrier function.

Abstract: A cleansing composition comprising surfactants comprising decyl glucoside and coco glucoside, wherein the decyl glucoside is present in an amount by weight that is 1.5 to 2.5 times the weight of coco glucoside.

Abstract: The claimed invention is directed to compositions and methods effective in preventing microbial contamination or reducing microbial count associated with a contaminated surface, comprising a biocidal system comprised of a primary biocide, a pH buffer agent, a surfactant, all in an aqueous based carrier, wherein the compositions may be considered environmentally friendly.