Abstract: A composition is provided which comprises an acidic component, generally fulvic acid, having a molecular weight not exceeding 20,000 Daltons and a low content of the elements aluminium, mercury, cadmium, chromium and lead. The acidic component is preferably carbohydrate derived and preferably using a wet oxidation process.

Abstract: Silver-containing particles, and methods of making silver-containing particles are disclosed.

Abstract: The present invention provides a method for inducing Fallopian tube blockage as a means for female contraception. The method comprises contacting the inner surface tissue of a Fallopian tube with a silver nitrate bearing substrate, delivering an amount of silver nitrate to the tissue sufficient to induce blockage of the Fallopian tube. Preferably, the substrate is a bead. In one embodiment, at least one silver nitrate bearing bead is introduced through the uterine opening of the Fallopian tube by use of a catheter or other device suitable for manipulating the bead. Alternatively, a plurality of beads can be introduced into the Fallopian tube. In a preferred embodiment, one or more silver nitrate bearing beads are arranged on a string to facilitate later removal of the beads. The method of the present invention delivers an amount of silver nitrate to the tissue sufficient to cause tissue necrosis and blockage of the Fallopian tube.

Abstract: This invention relates to a non-medicinal food additive that is an animal growth promoter containing 99% pure zeolite partially or totally exchanged with a Cm+ cation, i.e., a synthetic zeolite, having the general formula I below: 1 m ? yC m + ? ( 1 - y ) ? 1 n ? M n + ? AlO 2 ? xSiO 2 in which x is greater than 1 and advantageously between 1 and 15; Mn+ represents an alkaline or alkaline earth exchangeable ion, advantageously Na+, K+, Ca2+ or Li+; n is between 1 and 2; y is the exchange rate and is between 0.001 and 1; Cm+ is a metallic cation chosen from among copper Cu2+, silver Ag+ or zinc Zn2+; m is between 1 and 2; this invention also relates to an additive premix and a supplemented food containing same and a method of improving the growth of animals.

Abstract: A stably-dispersed composite of metal nanoparticles and inorganic clay and a method for producing the composite, in which interlayered charges of the clay are replaced with the metal ions, which are then reduced to metal particles by a reducing agent. The metal particles will not aggregate together and can be stably uniformly dispersed with particle sizes smaller than conventional metal nanoparticles, and therefore have better antibiotic effect, catalytic ability and other advantages. Antibacterials in a solvent containing 0.01 wt % or more of the metal nanoparticles and inorganic clay are prepared and confirmed to be effective.

Abstract: A device or composition comprising an agent for the coagulation of protein-containing fluids, wherein the agent comprises an inorganic component which is soluble in protein-containing fluids. Use of such a device or composition for the coagulation of protein-containing fluids. A coagulum of protein-containing fluid produced using such a device or composition.

Abstract: There is provided a novel chain-end functionalized PEO of formulas (I) to (IV) prepared via living anionic polymerization and chain-end functionalization, as well as a simple method of preparing nano-sized transition metal or metal salt particles using the same, which can be readily stabilized even in an aqueous medium. The water-soluble PEO-based polymers having various functional groups (including a drug group such as vitamin and anti-cancer agent) and the process of preparing nano-sized transition metal or metal salt particles using the same can be advantageously used in the development of new materials for drug delivering system and imaging, e.g., a contrast agent and an anti-cancer agent simultaneously.

Abstract: The inventive pharmaceutical compositions relate to medicine and veterinary sciences, in particular to agents which exhibit a combined anti-tumoral, antibacterial and antiviral activity and can be used for producing medicinal and veterinary formulations. In the first variant, the composition contains in mass %: 0.016-1.6 silver nitrate, 0.07-0.7 alpha-asparaginic acid, 0.07-0.7 nicotinic acid, 0.03-1.4 hexamethylenetetramine, 0.02-5.0 sodium thiosulphate, the rest being water. In the second variant, the composition contains in mass %: 0.016-1.6 silver nitrate, 0.03-1.4 hexamethylenetetramine or imidazol, 0.056-5.6 cis-[Pt(NH3)2Im2]Cl2 or cis-[Pt(NH2OH)2Im2]Cl2, 0.07-0.7 alpha-asparagic acid or asparagin, 0.07-0.7 nicotinic acid, the rest being water. Said pharmaceutical compositions exhibit the anti-tumoral activity, which is greater than that of the known agent, and simultaneously perform antibacterial and antiviral action on an organism.

Abstract: An aqueous silver-containing solution comprising nano-sized silver particles wherein silver (Ag) particles having a particle diameter of 1 to 20 nm have a concentration of 200 to 100,000 ppm, the pH of the solution is maintained in a range of 6 to 8.5, and based on the weight of the silver-containing solution, an amount of a stabilizer as an impurity is in a range of 0.5 to 1.5% by weight, an amount of anions of a silver salt as another impurity is 1.0% by weight or less and the total amount of the stabilizer and anions of the silver salt is 2.0% by weight or less; an antibacterial resin composition comprising 100 parts by weight of an acrylic, urethane, epoxy or ester resin, 0.

Abstract: Formulations have been developed which assist individuals having an addiction such as smoking to reduce or quit engaging in the addictive behavior. Representative behaviors include smoking, excessive alcohol or food ingestion, drug addiction, and ingestion of caffeine or junk food providing quick “highs”. The formulations assist the smoker to become dissatisfied with smoking, until he or she willingly gives up the habit or at least cuts down on the number of cigarettes smoked per day as an initial step towards quitting in the future. The formulations can also be used in conjunction with other known formulations, such as nicotine gum or patch. The formulations contain hydrophilic polymers, for example, polyethylene glycol (PEG) alone or in combination or polyvinyl pyrrolidone (PVP) (also known as povidone or polyvidone alone or in combination.), sweeteners and/or flavorings, viscosity modifiers/binders, and pH or buffering agents.

Abstract: An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and sponges. The composition includes macrosize or submicron particles of silver, platinum with silver and their salts with parabens, oxide, salicylate, acetate, citrate, benzoate and phosphate along with copper and zinc salts of the same.

Abstract: The invention relates to biologically active nanoparticles of a carbonate-substituted non-stoichiometric hydroxyapatite, having: a) a crystallinity degree CD lower than 40%, the crystallinity degree being defined as CD=(1?X/Y)·100 wherein: Y=height of the diffraction maximum at 2?=33°, X=height of the diffraction background at 2?=33° of the nanoparticles X-ray diffraction pattern; b) a length L ranging from 20 to 200 nm and a width W ranging from 5 to 30 nm; and c) an aspect ratio AR comprised between 2 and 40, the aspect ratio being defined as AR=L/W. The biologically active nanoparticles of the invention find a preferred use in oral or dental hygiene applications and may be formulated as compositions for oral or dental hygiene such as, for example, solutions, suspensions, oils, gels or other solid products.

Abstract: A multi-layer film for reducing microbial contamination on a surface. The multi-layer film can include a core layer having a first surface and a second surface opposite the first surface, an adhesive layer disposed adjacent the first surface of the core layer, and an antimicrobial layer disposed adjacent the second surface. The antimicrobial layer can include a cross-linked matrix and an antimicrobial agent dispersed within the cross-linked matrix, where the cross-linked matrix is derived from a polymerizable precursor comprising a material selected from the group consisting of a polymerizable monomer, a polymerizable polymer having a molecular weight of about 1,000 or less, and combinations thereof.

Abstract: The invention provides a fluid-wicking, antimicrobial fiber formed of a grooved fiber comprising an antimicrobial material. Fabrics and products comprising the fluid-wicking, antimicrobial fiber are also provided. A medical device of the invention, for example a wound dressing, demonstrates antibacterial and optionally antifungal properties, depending on the selection of the antimicrobial material contained therein, with the medical device demonstrating the ability to wick fluids away from the surface of a wound and hold the fluids within an absorbent layer of the device.

Abstract: Silver nanoparticles are mixed with a chitosan solution, to form a chitosan/silver nanoparticle dispersion, which is then subjected to a freeze-drying process, to form a chitosan/silver nanoparticle matrix suitable for use as a wound dressing.

Abstract: The present invention provides compositions and methods for decreasing photosensitivity induced by photodynamic therapy (PDT). The compositions and methods of the present method employ porphyrin complexing molecules as agents for reducing photosensitivity.

Abstract: A material for the treatment or prophylaxis of microbial, including bacterial, infections, comprising a metal species and a polymer, wherein the polymer stabilises the metal species. Compositions and devices comprising the material. A method for the treatment or prophylaxis of microbial, including bacterial, infections, comprising the use of such a material, composition or device.

Abstract: There is provided a method for treating a fluid with an anti-microbial agent comprising the steps of: (a) contacting the fluid with a solid material containing an anti-microbial agent; and, (b) abrading an interface of the solid material and removing particles therefrom and exposing an underlying surface of the solid material to the fluid, thereby facilitating release of the antimicrobial agent of the underlying surface of the solid material and/or the removed particles into the fluid. The solid material comprises an anti-microbial agent dispersed and/or embedded in a solid carrier. Typically, the anti-microbial agent is one or more of a metal, metal oxide, metal compound, metal salt, metal-ligand complex or derivatives thereof based on silver, copper and zinc.

Abstract: An occlusive wound dressing for application to wound sites to accelerate the healing process and improve the appearance of the final mature scar including a silicone gel sheet and antimicrobial silver disposed in the silicone gel sheet where the silver may be present in the form of particles or wires and the particles or wires may be disposed in the silicone gel sheet in a grid pattern or as a lattice, and an adhesive may be present on at least one face of the silicone gel sheet. The adhesive may be present in the form of spaced lines with adhesive-free areas between the lines containing the antimicrobial silver. It is preferred that an antibruising agent is also included in the silicone gel.

Abstract: A hemostatic biocidal dressing includes pro-coagulant and biocidal agents providing a physical barrier to bleeding as well as chemical action to promote blood coagulation and thereby arrest coverage. At the same time, biocidal properties of the dressing prevent the introduction of infected agents and the establishment of infection within wounded tissue. A silverized textile provides biocidal action while a granulated hemostatic agent disposed within interstitial regions between polymer fibers provides coagulating action.

Abstract: A two part biocide composition containing metal ions and bromine donor for killing microorganisms in a body of water and a method of killing microorganisms in a body of water by placing both metal ions and a bromine in the body of water to allow use of lower concentrations of bromine than if bromine were used alone as a biocide.

Abstract: A vitreous antimicrobial agent that can exhibit excellent antimicrobial properties when added to various types of resins, that has excellent discoloration resistance and hot water resistance, and that can easily be produced at a commercial scale. The vitreous antimicrobial agent includes, relative to 100 mass % of total glass components, 0.1 to 2 mass % of Ag2O, 40.5 to 49 mass % of ZnO, 6 to 9.5 mass % of SiO2, 30.5 to 39.5 mass % of B2O3, 2 to 10 mass % of an alkaline earth metal oxide, and 6 to 7.5 mass % of Na2O; the vitreous antimicrobial agent comprising, in addition to these, 0.01 to 5 mass % of CeO2 as necessary. An antimicrobial resin composition and an antimicrobial product including the vitreous antimicrobial agent.

Abstract: A tissue adhesive antimicrobial material that is placed into a tooth extraction site for the sustained release of silver for the prevention and treatment of alveolar osteitis. The antimicrobial material is placed into a tooth extraction site via syringe, hand instrument or hand delivery device.

Abstract: A nano silver active material disclosed for use in agriculture. The active material prevents and treats major diseases in agricultural field.

Abstract: The present invention is a quick-kill formulation that is able to kill organisms such as bacteria, viruses, fungi, mold, spore-forming bacteria and combinations thereof. In addition, the formulation contains a residual kill component that is effective for at least one day. The unique formulation is effective without being corrosive. This is an advantage that allows it to be used in a wide range of applications, one application being in the medical field for sterilizing instruments. Another improvement of this formulation over the prior art is that it is stabilized such that, unlike prior art formulations, tap water, as opposed to distilled water, may be used in its manufacture.

Abstract: The present invention is to provide a silver-based inorganic antimicrobial agent that has excellent heat resistance and chemical resistance, that gives little resin coloration, and that has excellent processability. It has been found that the object can be attained by a silver ion-containing zirconium phosphate represented by Formula (1) below by limiting the production conditions to wet synthesis, and the present invention has thus been accomplished. Aga MbZrc(PO4)3.nH2O??(1) In Formula (1), M is at least one type of ion selected from an alkali metal ion, a hydrogen ion, and an ammonium ion, a, b, and c are positive numbers and satisfy 1.5?c?2 and a+b+4c=9, and n is no greater than 2.

Abstract: A delivery vehicle for a silver ion source such as silver nitrate and the like, suitable for use in the treatment of menorrhagia, comprises a plurality of physiologically inert beads bearing a tissue cauterizing amount of a silver ion source. Preferably the beads are made of a physiologically inert polymer, ceramic or stainless steel. The silver ion source preferably is silver nitrate and can be substantially pure silver nitrate, or can comprise silver nitrate in combination with a physiologically tolerable binder or a diluent. Suitable binders include physiologically tolerable synthetic polymeric binders, polysaccharide binders, and the like. Diluents can include other salt materials such as potassium nitrate. The beads are useful in treating menorrhagia of a mammalian uterus. The beads can be delivered to the uterus via a catheter, and are distributed throughout the uterine cavity by uterine massage or like expedient. Silver ions are delivered to the endometrium and cause necrosis of the endometrial tissue.

Abstract: A two part biocide composition containing metal ions and bromine donor for killing microorganisms in a body of water and a method of killing microorganisms in a body of water by placing both metal ions and a bromine in the body of water to allow use of lower concentrations of bromine than if bromine were used alone as a biocide.

Abstract: A wearing article includes an article element and a fastening mechanism. The article element includes at least one pack unit that has a fabric housing and a flexible pad body fitted into the fabric housing and including a thin elastic matrix of an elastic material and a plurality of functional particles dispersed in the matrix and capable of providing at least one of the functions consisting of emitting far-infrared rays, emitting negative ions, and destroying bacteria. The fastening mechanism is secured to the pack unit so as to permit wearing of the pack unit by the human body and abutment of the fabric housing against the human body.

Abstract: The present invention relates to combinations of imazalil, or a salt thereof, and silver compounds which provide an improved biocidal effect. More particularly, the present invention relates to compositions comprising a combination of imazalil, or a salt thereof, together with one or more silver salts selected from silver acetate, silver alginate, silver azide, silver citrate, silver lactate, silver nitrate, silver sulfate, silver chloride, silver thiocyanate, silver-sodium-hydrogen-zirconium phosphate, silver sulfadiazine, silver cyclohexanediacetic acid and disilver 2,5-dichloro-3,6-dihydroxy-2,5-cyclohexadiene-1,4-dione; in respective proportions to provide a synergistic biocidal effect.

Abstract: By providing a therapeutic agent in a mixture with water in combination with at least one selected from the group consisting of surfactants, excipients, thickening agents, and water, a unique, improved, liquid based foam or spray and/or gel producing formulation is realized which is useable for a wide variety of applications. In the preferred embodiment, the improved formulations incorporate one or more therapeutic agents which comprise a silver-based composition. As a result, the formulation is useable for a wide variety of medical applications for preventing, treating, or reducing the spread or transmission of bacteria, virus, infections, and the like.

Abstract: The present invention is drawn to disinfectant or sterilant compositions, which are human safe, e.g., food grade or food safe. In one embodiment, an aqueous disinfectant or sterilant composition can comprise an aqueous vehicle, including water, from 0.001 wt % to 50 wt % of a peracid, and from 0.001 wt % to 25 wt % of a peroxide. Additionally, from 0.001 ppm to 50,000 ppm by weight of a transition metal based on the aqueous vehicle content can also be present. The composition can be substantially free of aldehydes. Alternatively or additionally, the transition metal can be in the form of a colloidal transition metal.

Abstract: The invention enables management of mammalian disease related to decreased energy production in the mitochondria, the powerhouse of the cell. The invention uses the combination of liposomal reduced glutathione and l-arginine to increase the ability weight loss in individuals with excess weight. The mechanism of weight loss appears to be related to improving the inefficient production of energy by the respiratory transport chain of mitochondria, the function of which are influenced positively by the availability of antioxidant nitric oxide in a non-oxidized environment. This invention enables weight loss in individuals who's inability to lose weight is related to inefficiency of the biochemical pathways facilitating mitochondrial function and energy production. The pathways related to inability to lose weight are also related to the phenomenon of the inability to metabolize fats, which results in insulin resistance and diabetes. The invention is useful for the management of the metabolic syndrome.

Abstract: A deodorant antimicrobial fibrous product containing a cancrinite-like mineral containing an antimicrobial metal, a clay mineral, softwood bleached kraft pulp, and hardwood bleached kraft pulp. The weight ratio of the softwood bleached kraft pulp to hardwood bleached kraft pulp is preferably 95/5 to 50/50. The clay mineral is preferably zeolite, sepiolite or bentonite. The deodorant antimicrobial fibrous product is preferably in the form of a sheet or a broken piece thereof, a granule or a three-dimensional molding.

Abstract: A method for producing a silver-bonded antimicrobial moist wound dressing. A silver-containing compound is added to a 0.1-30% aqueous solution of an alkaline solvent to dissociate silver ions from the silver-containing compound, dissolving CMC in water or an organic solvent to obtain a CMC solution, the silver ion-containing solution is mixed with the CMC solution so that the hydrogen ions (H+) of the hydroxyl groups of the CMC are replaced by the silver ions to prepare a silver-CMC compound, the silver-CMC compound is dispersed and absorbed in a medium, and the medium is dried.

Abstract: The present invention is directed to an antimicrobial composition, comprising pyrithione or a pyrithione complex; and a zinc or copper or silver source selected from the group consisting of zinc or copper or silver salts, oxides, hydroxides, sulfates, chlorides, metals, and combinations thereof; wherein the weight ratio of the zinc or copper or silver source to the pyrithione or the pyrithione complex is in the range from about 1:300 to about 50:1, and wherein the antimicrobial composition has an enhanced biocidal effect against a variety of free-living microorganisms or biofilms. Also disclosed is a method of inhibiting the growth of free-living microorganisms or biofilm utilizing the above antimicrobial composition, as well as use of such antimicrobial compositions in various products including fuels, fluids, lubricants, coatings, adhesives, sealants, elastomers, soaps, cosmetics, plastic or woven or non-woven fibers, pharmaceuticals, and as preservatives for the above products.

Abstract: An antibacterial agent composed of silver-containing aluminum sulfate hydroxide particles represented by the following formula (X-I) or (Y-I). (AgaBb-a)bAlcAx(SO4)y(OH)z.pH2O??(X-I) [AgaBb-a]b[Ti3-cAlc](SO4)y(OH)z.pH2O??(Y-I) The above antibacterial agent of the present invention provides antibacterial molded articles and further antifungal agents, cosmetics, antibacterial paper, antibacterial deodorizing sprays and agricultural chemicals when it is mixed with a resin.

Abstract: A method of disinfecting surfaces said method comprising applying a disinfectant solution to surface to be disinfected and allowing the solvent to evaporate or wiping the excess solution from the surface after a period of time wherein the solution is an antimicrobial metal ion-acid solution.

Abstract: The present invention comprises methods and compositions for antimicrobial devices comprising metal containing compositions which are resistant to heat and light discoloration. The metal containing compositions may comprise salts or complexes of silver, copper or zinc. In one aspect the compositions comprise silver salts. In another aspect, the compositions comprise silver complexes. In one aspect, the metal salts may comprise metal salts of saccharin, acesulfame, long chain fatty acids, and alkyl dicarboxylic acids. The compositions further comprise polymers which form salts or complexes with silver, copper or zinc. The methods of the present invention comprise treating devices with the metal containing compositions, including, but not limited to, such devices as woven wound care materials, catheters, patient care devices, and collagen matrices. The present invention further comprises treatment of humans and animals with the antimicrobial devices described herein.

Abstract: The invention relates to an antimicrobial and preferably non-cytotoxic coating material and to use of said coating material.

Abstract: The invention is an antimicrobial photo-stable coating composition that deters photo-induced discoloration, does not stain tissue and can be applied to the surface of a variety of medical materials. The composition comprises in an aspect silver-PCA complex and dye.

Abstract: A new, novel and useful disinfection and purification system comprised of organic compounds in synergistic action with selected metal ions and method of manufacture and use. One of the benefits that is derived from this system is the ability to quickly and easily treat a surface, fluid or medium for disinfection of bacteria, fungi, viruses, algae and protozoans, with a non-toxic, non-chlorinated mixture that effectively kills all such organisms in minutes or hours. The disinfection and purification system remains effective for long periods of time maintaining its disinfection capacity making it highly effective for stored or transported mediums such as potable drinking water. The disinfection and purification system may be incorporated with carbon block or membrane filters to disinfect filtered liquids such as water to render it potable.

Abstract: The present invention provides wood preservative compositions comprising micronized particles. In one embodiment, the composition comprises dispersions of micronized metal or metal compounds. In another embodiment, the wood preservative composition comprises an inorganic component comprising a metal or metal compound and organic biocide. When the composition comprises an inorganic component and an organic biocide, the inorganic component or the organic biocide or both are present as micronized particles. When compositions of the present invention are used for preservation of wood, there is minimal leaching of the metal and biocide from the wood.

Abstract: The present invention relates to a cosmetic pigment composition exhibiting colors in the visible region, which comprises an effective amount of nanoparticles or a mixture of two or more nanoparticles selected from the group consisting of (a) gold nanoparticles exhibiting red color; (b) silver nanoparticles exhibiting yellow color; (c) gold-silver alloy nanoparticles exhibiting flame color; and (d) gold nanoparticles exhibiting blue color, and a color cosmetic composition and a color lotion comprising the pigment composition. According to the present invention, it is possible to prepare pigments exhibiting various colors in the visible region using gold or silver nanoparticles, and a cosmetic pigment composition which can exhibit various colors by mixing the pigments in various compositional ratios, in which precipitation or agglomeration of particles does not occur, and whose color can be maintained for a long time.

Abstract: The invention is related to gel preparations capable of absorbing as well as releasing liquid, and the use of such gel preparations in the treatment of wounds.

Abstract: A delivery means, for example a dressing, for delivering an antibacterial metal, for example silver, comprises the metal in combination with a hydrophilic polymer. The polymer may be cross-linked by a butylidene polymer to define a gel. In the examples, silver nitrate may be reduced to metallic silver, protected using polyvinylalcohol which is cross-linked to define a gel.

Abstract: A method for controlling fire ants is described, which includes applying a silver-containing composition to an area infested by fire ants or threatened by an infestation. The composition is applied to the area and reduces or eliminates the colony within a period of about two to four weeks and prevents fire ant re-infestation for a period of about six months to one year.

Abstract: Anti-microbial sheet, and derived product like tile, in particular for medical application, includes a polymeric base including a support layer and an anti-microbial additive in a cover—or anti-microbial layer of significantly lower thickness as compared to the support. The anti-microbial layer is of a composition including the support material and the microbial additive. Effectiveness is increased by a relatively increased concentration of additive in the cover layer, while product cost is reduced due to minimising the active layer to a superficial thickness, typically in a range of 25 to 100 ?m. Cost is further reduced by using known co-extrusion allowing further enhancement of the product here by addition of glass flakes, in particular solely to the support layer. Using co-extrusion enables continuous manufacture, reducing costs, by cutting the sheet material at exit into sheets, and allowing relatively increased thicknesses, up to 35 mm.

Abstract: The present invention relates to a pharmaceutical composition comprising an effective amount of silver nanoparticles, a method for increasing hair growth by administering the said pharmaceutical composition locally to a host and use thereof.

Abstract: Disclosed herein is a colorless and transparent antibiotic material including silver and a method of preparing the same. Specifically, the current invention pertains to a method of preparing a colorless and transparent antibiotic material including silver (Ag), which includes a) reacting a salt including a silver ion (Ag+) with a salt including a sulfate anion, to prepare a silver (Ag)-sulfate complex; and b) diluting the silver (Ag)-sulfate complex prepared in a) with water, and to an antibiotic material prepared using the method. Further, the current invention pertains to an antibiotic material including silver, which is harmless to the human body and exhibits disinfecting and antibiotic activities, and as well, is colorless and transparent and does not easily form colored oxides, unlike conventional silver-based antibiotic materials, and to a method of preparing such an antibiotic material.